Sstr5 (somatostatin receptor 5) - Rat Genome Database

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Gene: Sstr5 (somatostatin receptor 5) Rattus norvegicus
Analyze
Symbol: Sstr5
Name: somatostatin receptor 5
RGD ID: 3765
Description: Enables somatostatin receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and cellular response to glucocorticoid stimulus. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in bipolar disorder. Orthologous to human SSTR5 (somatostatin receptor 5); PARTICIPATES IN bipolar disorder pathway; INTERACTS WITH (+)-pilocarpine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Smstr5; SOMATO; Somatostatin receptor subtype 5; somatostatin receptor type 5; SS-5-R; SS5-R; SS5R
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,010,209 - 15,017,469 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,011,391 - 15,017,469 (-)EnsemblGRCr8
mRatBN7.21014,506,868 - 14,512,946 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,506,868 - 14,512,946 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1019,247,393 - 19,253,474 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,736,266 - 18,742,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,235,447 - 14,241,528 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,847,749 - 14,853,827 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,847,749 - 14,853,827 (-)Ensemblrn6Rnor6.0
Rnor_5.01014,664,005 - 14,670,083 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41014,740,991 - 14,747,069 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1014,177,783 - 14,183,861 (-)NCBICelera
RGSC_v3.11014,740,990 - 14,747,069 (-)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
neuron projection  (IBA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat. Bruno JF, etal., Endocrinology. 1994 Nov;135(5):1787-92.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy. Kumar U, etal., Endocrinology. 1997 Oct;138(10):4473-6.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Novel polymorphisms in the somatostatin receptor 5 (SSTR5) gene associated with bipolar affective disorder. Nyegaard M, etal., Mol Psychiatry 2002;7(7):745-54.
8. Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28. O'Carroll AM, etal., Mol Pharmacol 1992 Dec;42(6):939-46.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Role of glucocorticoids in the regulation of pituitary somatostatin receptor subtype (sst1-sst5) mRNA levels: evidence for direct and somatostatin-mediated effects. Park S, etal., Neuroendocrinology. 2003 Sep;78(3):163-75.
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:7908405   PMID:15919085   PMID:17156933   PMID:17617126   PMID:18566118   PMID:21820437   PMID:22872212   PMID:22888021   PMID:23112170   PMID:24699281   PMID:24846611   PMID:25926390  
PMID:27984180  


Genomics

Comparative Map Data
Sstr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,010,209 - 15,017,469 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,011,391 - 15,017,469 (-)EnsemblGRCr8
mRatBN7.21014,506,868 - 14,512,946 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,506,868 - 14,512,946 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1019,247,393 - 19,253,474 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,736,266 - 18,742,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,235,447 - 14,241,528 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,847,749 - 14,853,827 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,847,749 - 14,853,827 (-)Ensemblrn6Rnor6.0
Rnor_5.01014,664,005 - 14,670,083 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41014,740,991 - 14,747,069 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1014,177,783 - 14,183,861 (-)NCBICelera
RGSC_v3.11014,740,990 - 14,747,069 (-)NCBI
Cytogenetic Map10q12NCBI
SSTR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,072,747 - 1,081,454 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,063,867 - 1,081,467 (+)Ensemblhg38GRCh38
GRCh37161,122,747 - 1,131,454 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,068,870 - 1,069,964 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34161,068,869 - 1,069,964NCBI
Celera161,337,406 - 1,346,174 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,054,012 - 1,062,283 (+)NCBIHuRef
CHM1_1161,122,700 - 1,131,395 (+)NCBICHM1_1
T2T-CHM13v2.0161,084,408 - 1,093,211 (+)NCBIT2T-CHM13v2.0
Sstr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,708,849 - 25,716,262 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,708,847 - 25,733,577 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381725,489,875 - 25,497,288 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,489,875 - 25,497,288 (-)Ensemblmm10GRCm38
MGSCv371725,626,820 - 25,634,198 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361725,217,475 - 25,224,853 (-)NCBIMGSCv36mm8
Celera1726,022,519 - 26,029,900 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.62NCBI
Sstr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,168,941 - 16,176,203 (-)Ensembl
ChiLan1.0NW_00495544216,169,069 - 16,176,054 (-)NCBIChiLan1.0ChiLan1.0
SSTR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,317,330 - 1,334,043 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,099,251 - 5,116,128 (+)NCBINHGRI_mPanPan1
SSTR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,608,813 - 39,610,138 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,874,995 - 40,876,320 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0639,953,430 - 39,954,755 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,952,401 - 39,958,911 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,629,880 - 39,631,205 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,602,521 - 39,603,846 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,081,232 - 40,082,557 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sstr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,962,956 - 111,970,071 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650162,031 - 63,122 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650160,812 - 63,149 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSTR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,756,457 - 40,762,895 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1340,756,465 - 40,758,111 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SSTR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15967,785 - 976,353 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5973,791 - 974,885 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606830,139,411 - 30,155,185 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sstr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,825,435 - 1,832,501 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249131,812,539 - 1,832,566 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sstr5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v192,753,678 - 2,760,566 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sstr5
49 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:45
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000025451
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
RH94731  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21014,512,830 - 14,512,939 (+)MAPPERmRatBN7.2
Rnor_6.01014,853,712 - 14,853,820NCBIRnor6.0
Rnor_5.01014,669,968 - 14,670,076UniSTSRnor5.0
RGSC_v3.41014,746,954 - 14,747,062UniSTSRGSC3.4
Celera1014,183,746 - 14,183,854UniSTS
Cytogenetic Map10q12UniSTS
G67509  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21014,507,317 - 14,507,737 (+)MAPPERmRatBN7.2
Rnor_6.01014,848,199 - 14,848,618NCBIRnor6.0
Rnor_5.01014,664,455 - 14,664,874UniSTSRnor5.0
RGSC_v3.41014,741,441 - 14,741,860UniSTSRGSC3.4
Celera1014,178,233 - 14,178,652UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 45 4 1 1 13 2 1 44 1 27 1 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000025451   ⟹   ENSRNOP00000025451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,011,391 - 15,017,469 (-)Ensembl
mRatBN7.2 Ensembl1014,506,868 - 14,512,946 (-)Ensembl
Rnor_6.0 Ensembl1014,847,749 - 14,853,827 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080944   ⟹   ENSRNOP00000072638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1014,847,818 - 14,848,967 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133850   ⟹   ENSRNOP00000109656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,011,596 - 15,017,351 (-)Ensembl
RefSeq Acc Id: NM_012882   ⟹   NP_037014
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,011,391 - 15,017,469 (-)NCBI
mRatBN7.21014,506,868 - 14,512,946 (-)NCBI
Rnor_6.01014,847,749 - 14,853,827 (-)NCBI
Rnor_5.01014,664,005 - 14,670,083 (-)NCBI
RGSC_v3.41014,740,991 - 14,747,069 (-)RGD
Celera1014,177,783 - 14,183,861 (-)RGD
Sequence:
RefSeq Acc Id: XM_063268457   ⟹   XP_063124527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,010,209 - 15,017,432 (-)NCBI
RefSeq Acc Id: NP_037014   ⟸   NM_012882
- UniProtKB: P30938 (UniProtKB/Swiss-Prot),   G3V8G3 (UniProtKB/TrEMBL),   A6HD30 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072638   ⟸   ENSRNOT00000080944
Ensembl Acc Id: ENSRNOP00000025451   ⟸   ENSRNOT00000025451
RefSeq Acc Id: XP_063124527   ⟸   XM_063268457
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000109656   ⟸   ENSRNOT00000133850
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30938-F1-model_v2 AlphaFold P30938 1-363 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3765 AgrOrtholog
BioCyc Gene G2FUF-25776 BioCyc
Ensembl Genes ENSRNOG00000018834 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000025451 ENTREZGENE
  ENSRNOT00000133850 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Somatstn_rcpt UniProtKB/Swiss-Prot
  Somatstn_rcpt_5 UniProtKB/Swiss-Prot
NCBI Gene 25354 ENTREZGENE
PANTHER NEUROPEPTIDES RECEPTOR UniProtKB/Swiss-Prot
  SOMATOSTATIN RECEPTOR TYPE 5 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Sstr5 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  SOMATOSTATNR UniProtKB/Swiss-Prot
  SOMATOSTTN5R UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018834 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
TIGR TC224605
UniProt A0ABK0LU18_RAT UniProtKB/TrEMBL
  A6HD30 ENTREZGENE, UniProtKB/TrEMBL
  G3V8G3 ENTREZGENE, UniProtKB/TrEMBL
  P30938 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Sstr5  somatostatin receptor 5    Somatostatin receptor subtype 5  Symbol and Name updated 629477 APPROVED
2002-06-10 Sstr5  Somatostatin receptor subtype 5      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed only in pituitary 727545
gene_physical_interaction highest affinity for somatostatin 28 727545
gene_process activation results in a decrease of intracellular cAMP levels 727545
gene_process activates inhibitory G-proteins 727545
gene_product member of the seven transmembrane domain superfamily of G-protein coupled receptors 727545