Rpph1 (ribonuclease P RNA component H1) - Rat Genome Database

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Gene: Rpph1 (ribonuclease P RNA component H1) Rattus norvegicus
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Symbol: Rpph1
Name: ribonuclease P RNA component H1
RGD ID: 3580
Description: Predicted to enable ribonuclease P activity. Predicted to be involved in tRNA processing. Predicted to be part of ribonuclease P complex. Orthologous to human RPPH1 (ribonuclease P RNA component H1); INTERACTS WITH 3-chloropropane-1,2-diol; acetamide; bisphenol A.
Type: ncrna (Ensembl: ribozyme)
RefSeq Status: PROVISIONAL
Previously known as: Rmrp; Rmrp1; RNA component of mitochondrial RNA processing endoribonuclease; RNA component of mitochondrial RNAase P; RNA component of mitochondrial RNAase P, 1; RNA component of RNAase MRP 1
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,507,232 - 26,507,488 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1526,507,215 - 26,507,512 (-)EnsemblGRCr8
mRatBN7.21524,033,679 - 24,033,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,033,662 - 24,033,959 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1526,804,873 - 26,805,129 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,763,609 - 27,763,865 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,013,411 - 26,013,667 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,738,989 - 27,739,245 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,738,972 - 27,739,269 (-)Ensemblrn6Rnor6.0
Rnor_5.01531,571,414 - 31,571,670 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41526,789,869 - 26,790,125 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1524,353,170 - 24,353,426 (-)NCBICelera
RGSC_v3.11526,805,568 - 26,805,824 (-)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Nucleotide sequences of the RNA subunit of RNase P from several mammals. Altman S, etal., Genomics 1993 Nov;18(2):418-22.
2. Long noncoding RNA dysregulation in ischemic heart failure. Greco S, etal., J Transl Med. 2016 Jun 18;14(1):183. doi: 10.1186/s12967-016-0926-5.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:35416722  


Genomics

Comparative Map Data
Rpph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,507,232 - 26,507,488 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1526,507,215 - 26,507,512 (-)EnsemblGRCr8
mRatBN7.21524,033,679 - 24,033,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,033,662 - 24,033,959 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1526,804,873 - 26,805,129 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,763,609 - 27,763,865 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,013,411 - 26,013,667 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,738,989 - 27,739,245 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,738,972 - 27,739,269 (-)Ensemblrn6Rnor6.0
Rnor_5.01531,571,414 - 31,571,670 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41526,789,869 - 26,790,125 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1524,353,170 - 24,353,426 (-)NCBICelera
RGSC_v3.11526,805,568 - 26,805,824 (-)NCBI
Cytogenetic Map15p14NCBI
RPPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,343,071 - 20,343,411 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,343,075 - 20,343,407 (-)Ensemblhg38GRCh38
GRCh371420,811,230 - 20,811,570 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,881,070 - 19,881,410 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341419,881,069 - 19,881,407NCBI
Celera14672,376 - 672,716 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef14933,073 - 933,413 (-)NCBIHuRef
CHM1_11420,812,656 - 20,812,996 (-)NCBICHM1_1
T2T-CHM13v2.01414,539,966 - 14,540,306 (-)NCBIT2T-CHM13v2.0
Rpph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,044,904 - 51,045,228 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,044,906 - 51,045,224 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381450,807,447 - 50,807,771 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,807,449 - 50,807,767 (-)Ensemblmm10GRCm38
MGSCv371451,427,122 - 51,427,446 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361449,729,398 - 49,729,722 (+)NCBIMGSCv36mm8
Celera1447,098,555 - 47,098,858 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.25NCBI

Variants

.
Variants in Rpph1
28 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
UniSTS:492996  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21524,033,659 - 24,033,963 (+)MAPPERmRatBN7.2
Rnor_6.01527,738,970 - 27,739,273NCBIRnor6.0
Rnor_5.01531,571,395 - 31,571,698UniSTSRnor5.0
RGSC_v3.41526,789,850 - 26,790,153UniSTSRGSC3.4
Celera1524,353,151 - 24,353,454UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 59 145 91 90 59 79 59 6 326 162 1 130 81 80 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000080198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1526,507,215 - 26,507,512 (-)Ensembl
mRatBN7.2 Ensembl1524,033,662 - 24,033,959 (-)Ensembl
Rnor_6.0 Ensembl1527,738,972 - 27,739,269 (-)Ensembl
RefSeq Acc Id: NR_002703
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,507,232 - 26,507,488 (-)NCBI
mRatBN7.21524,033,679 - 24,033,935 (-)NCBI
Rnor_6.01527,738,989 - 27,739,245 (-)NCBI
Rnor_5.01531,571,414 - 31,571,670 (-)NCBI
RGSC_v3.41526,789,869 - 26,790,125 (-)RGD
Celera1524,353,170 - 24,353,426 (-)RGD
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3580 AgrOrtholog
BioCyc Gene G2FUF-14058 BioCyc
Ensembl Genes ENSRNOG00000054493 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000080198 ENTREZGENE
NCBI Gene 29536 ENTREZGENE
PhenoGen Rpph1 PhenoGen
RatGTEx ENSRNOG00000054493 RatGTEx
RNAcentral URS000063DB53 RNACentral
  URS0000654455 RNACentral
  URS0000B2DAA6 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-26 Rpph1  ribonuclease P RNA component H1  Rmrp  RNA component of mitochondrial RNA processing endoribonuclease  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Rmrp  RNA component of mitochondrial RNA processing endoribonuclease  Rmrp  RNA component of mitochondrial RNAase P  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Rmrp  RNA component of mitochondrial RNAase P  Rmrp1  RNA component of mitochondrial RNAase P, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Rmrp1  RNA component of mitochondrial RNAase P, 1  Rmrp  RNA component of mitochondrial RNAase P   Symbol and Name updated 629477 APPROVED
2002-06-10 Rmrp  RNA component of mitochondrial RNAase P       Name updated 70584 APPROVED