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Gene: Zfp354a (zinc finger protein 354A) Rattus norvegicus

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Symbol:

Zfp354a

Name:

zinc finger protein 354A

RGD ID:

2967

Description:

Enables DNA-binding transcription factor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nucleolus organization; and response to folic acid. Predicted to be active in nucleus. Orthologous to human ZNF354A (zinc finger protein 354A); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Kid1; Kidney 1; kidney, ischemia, and developmentally-regulated protein 1; renal transcription factor Kid-1; TCF-17; Tcf17; transcription factor 17; Znf354a

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF354A (zinc finger protein 354A)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB
Mus musculus (house mouse):	Zfp354a (zinc finger protein 354A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF354A (zinc finger protein 354A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF354A (zinc finger protein 354A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf354a (zinc finger protein 354A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF354B (zinc finger protein 354B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF354A (zinc finger protein 354A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF354B (zinc finger protein 354B)	HGNC	OrthoDB, Treefam
Homo sapiens (human):	ZNF599 (zinc finger protein 599)	HGNC	PhylomeDB
Alliance orthologs ³
Mus musculus (house mouse):	Zfp354a (zinc finger protein 354A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ZNF354A (zinc finger protein 354A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ZNF354A (zinc finger protein 354A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ZAP1	Alliance	DIOPT (Hieranoid\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	znf484	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	znf665	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	znf665	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	znf470	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	LOC116406477	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	LOC101732725	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	LOC101734939	Alliance	DIOPT (Ensembl Compara\|OMA)
Xenopus tropicalis (tropical clawed frog):	LOC101731927	Alliance	DIOPT (Ensembl Compara\|OMA)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	35,897,217 - 35,909,063 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	35,897,228 - 35,909,510 (+)	Ensembl				GRCr8
mRatBN7.2	10	35,396,242 - 35,408,069 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	35,396,231 - 35,408,068 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	40,090,257 - 40,102,066 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	39,580,564 - 39,592,373 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	35,083,940 - 35,095,749 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	36,586,495 - 36,600,172 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	36,589,181 - 36,600,469 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	36,356,854 - 36,370,682 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	36,654,406 - 36,665,659 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	34,753,775 - 34,765,028 (+)	NCBI		Celera
RGSC_v3.1	10	36,655,454 - 36,666,708 (+)	NCBI
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

in situ carcinoma (ISO)

Reperfusion Injury (IEP)

seminoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,4,7,8-Pentachlorodibenzofuran (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

Actein (EXP)

aflatoxin M1 (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP)

bisphenol F (EXP)

bromobenzene (EXP)

buspirone (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

chlorpyrifos (ISO)

cobalt dichloride (EXP)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

epoxiconazole (ISO)

erythromycin estolate (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

flavonoids (EXP)

formaldehyde (ISO)

furan (EXP)

gamma-hexachlorocyclohexane (EXP)

genistein (EXP)

geraniol (ISO)

hydrogen peroxide (ISO)

isoflurane (ISO)

levofloxacin (EXP)

mercury dichloride (EXP)

metformin (EXP)

methamphetamine (EXP)

methapyrilene (EXP)

methimazole (EXP)

methotrexate (EXP)

mono(2-ethylhexyl) phthalate (ISO)

Muraglitazar (EXP)

N-nitrosodiethylamine (EXP)

orphenadrine (EXP)

oxycodone (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenformin (EXP)

phenobarbital (EXP,ISO)

pirinixic acid (EXP,ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

resveratrol (EXP)

sevoflurane (EXP)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sulindac (ISO)

tamoxifen (ISO)

Tesaglitazar (EXP)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (EXP,ISO)

triptonide (ISO)

troglitazone (EXP)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

kidney development (IEP)

negative regulation of transcription by RNA polymerase II (IEA,IMP)

nucleolus organization (IMP)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

response to folic acid (IEP)

response to hypoxia (IEP)

Cellular Component

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity (IEA,IMP)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

metal ion binding (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Expression of the transcriptional repressor protein Kid-1 leads to the disintegration of the nucleolus.	Huang Z, etal., J Biol Chem 1999 Mar 19;274(12):7640-8.
4.	Differential expression of the zinc finger gene TCF17 in testicular tumors.	Przyborski SA, etal., Cancer Res. 1998 Oct 15;58(20):4598-601.
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus.	Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10.	Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury.	Witzgall R, etal., Mol Cell Biol 1993 Mar;13(3):1933-42.

Additional References at PubMed

PMID:8020966	PMID:19519174	PMID:21630459	PMID:23665872

Genomics

Comparative Map Data

Zfp354a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	35,897,217 - 35,909,063 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	35,897,228 - 35,909,510 (+)	Ensembl				GRCr8
mRatBN7.2	10	35,396,242 - 35,408,069 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	35,396,231 - 35,408,068 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	40,090,257 - 40,102,066 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	39,580,564 - 39,592,373 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	35,083,940 - 35,095,749 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	36,586,495 - 36,600,172 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	36,589,181 - 36,600,469 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	36,356,854 - 36,370,682 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	36,654,406 - 36,665,659 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	34,753,775 - 34,765,028 (+)	NCBI		Celera
RGSC_v3.1	10	36,655,454 - 36,666,708 (+)	NCBI
Cytogenetic Map	10	q22	NCBI

ZNF354A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	178,711,512 - 178,730,659 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	178,711,512 - 178,732,381 (-)	Ensembl			hg38	GRCh38
GRCh37	5	178,138,513 - 178,157,660 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	178,071,128 - 178,090,309 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	178,071,127 - 178,090,309	NCBI
Celera	5	173,765,092 - 173,784,470 (-)	NCBI		Celera
Cytogenetic Map	5	q35.3	NCBI
HuRef	5	172,864,540 - 172,883,740 (-)	NCBI		HuRef
CHM1_1	5	177,570,885 - 177,590,072 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	179,263,543 - 179,282,761 (-)	NCBI		T2T-CHM13v2.0

Zfp354a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	50,950,052 - 50,963,626 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	50,950,084 - 50,963,626 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	51,059,225 - 51,072,799 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	51,059,257 - 51,072,799 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	50,872,759 - 50,886,301 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	50,902,680 - 50,914,687 (+)	NCBI		MGSCv36	mm8
Celera	11	55,618,339 - 55,632,502 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	30.97	NCBI

ZNF354A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	173,652,871 - 173,716,286 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	171,792,413 - 171,855,824 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	173,869,993 - 173,931,852 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	181,126,400 - 181,145,294 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	181,126,400 - 181,141,632 (-)	Ensembl			panPan2	panpan1.1

ZNF354A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	2,897,998 - 2,918,304 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	2,898,234 - 2,917,725 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	3,041,879 - 3,062,266 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	2,874,551 - 2,894,729 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	2,767,184 - 2,894,724 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	2,845,270 - 2,865,424 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	2,923,862 - 2,944,209 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	3,164,893 - 3,185,279 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znf354a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	113,011,386 - 113,015,649 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	15,966 - 17,935 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936647	16,233 - 18,411 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF354B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	79,579,753 - 79,601,137 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	79,579,737 - 79,602,080 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	81,245,570 - 81,272,296 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF354A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	80,407,134 - 80,425,920 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	80,407,085 - 80,423,055 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666075	11,722,320 - 11,741,404 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Zfp354a
15 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	357
Count of miRNA genes:	223
Interacting mature miRNAs:	254
Transcripts:	ENSRNOT00000045596
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35893451	64140567	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31796281	76796281	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28950353	73950353	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35893263	64653589	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29800910	64653589	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2298480	Eau7	Experimental allergic uveoretinitis QTL 7		0.0049	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	35509383	80509383	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35893263	52293000	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
2289985	Bp305	Blood pressure QTL 305			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	29076978	74076978	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	29377046	52699134	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31129113	76129113	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	35509383	88177745	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Markers in Region

RH137320

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	35,407,774 - 35,407,957 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	36,599,878 - 36,600,060	NCBI	Rnor6.0
Rnor_5.0	10	36,370,388 - 36,370,570	UniSTS	Rnor5.0
RGSC_v3.4	10	36,665,412 - 36,665,594	UniSTS	RGSC3.4
Celera	10	34,764,781 - 34,764,963	UniSTS
RH 3.4 Map	10	385.0	UniSTS
Cytogenetic Map	10	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	91	59	6	355	191	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_052798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M96548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000045596 ⟹ ENSRNOP00000049437

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	35,897,228 - 35,909,510 (+)	Ensembl
mRatBN7.2 Ensembl	10	35,396,278 - 35,407,610 (+)	Ensembl
Rnor_6.0 Ensembl	10	36,589,181 - 36,599,618 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085203 ⟹ ENSRNOP00000070798

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	35,897,962 - 35,909,063 (+)	Ensembl
mRatBN7.2 Ensembl	10	35,396,968 - 35,408,068 (+)	Ensembl
Rnor_6.0 Ensembl	10	36,590,325 - 36,600,469 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097835 ⟹ ENSRNOP00000092943

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	35,897,228 - 35,909,057 (+)	Ensembl
mRatBN7.2 Ensembl	10	35,396,231 - 35,408,068 (+)	Ensembl

RefSeq Acc Id:

NM_052798 ⟹ NP_434685

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	35,897,263 - 35,909,063 (+)	NCBI
mRatBN7.2	10	35,396,269 - 35,408,069 (+)	NCBI
Rnor_6.0	10	36,588,872 - 36,600,125 (+)	NCBI
Rnor_5.0	10	36,356,854 - 36,370,682 (+)	NCBI
RGSC_v3.4	10	36,654,406 - 36,665,659 (+)	RGD
Celera	10	34,753,775 - 34,765,028 (+)	RGD

Sequence:

show sequence

GAACAGTCTAAGGGTGTTCACTTTGGGGACTCAGTGAGTCCCCCTCTGTTATGGAGTACAGTGT
CTCTTGAATCTTACTTCTGGAAATCCACGGACAAGAAGACTGGTGACCTATCGATTTTGTGATG
CCCACCCCTGGCTCCTGGTTCCCTCTCTAGAGGCAGAAGAGCCAGGCGCAGCTAATGGGACGCT
TTCGGAGATGCTGCGTCTGACAGGTGCGAAGCAACATGTGCAACTCCTTTCTTCTTCCTCCCCT
CAGATCCTCCTCCATCTTCACCCATCTTTAGAGGAAGAGCCTACAGAAAGAAGATGGCTCCTGA
GCAAAGAGAAGGGGCCTCTCAGGTGTCAGTGACATTTGAAGATGTGGCTGTGCTCTTTACTCGG
GACGAGTGGAAGAAGCTGGATCTGTCTCAGAGAAGCCTGTACCGTGAGGTGATGCTGGAGAATT
ACAGCAACCTGGCCTCCATGGCAGGATTCCTGTTTACCAAACCAAAGGTGATCTCCCTGTTGCA
GCAAGGAGAGGATCCCTGGCAGGTGGAGAAAGAGGGCCCCAGATACTTCTCTCTCGGATTGAAG
TGCAGTCATAGAACCACTAAGTCAACTCAAACACAAGACTCTTCATTTCAGGAACTGATTGTAA
GAAAATCTAAAAGAACCTTTGCCTTCGAACCTTTGAACATGAAGTCAGAAAATCTTTTCATACA
TGAAGGCAAATTAGAGGAAAAGTGGGATAAGAATACTTTGACTGTAGAAAGAAGCCATAAAAAC
AATGAATTTAGCCCAAAGTCCCATAGAGAAAAACGGTCCTCAGAATGTAAAAAGCAGATATCTT
ATTTATCTAACCCACCAGGAATCACACCGGATAAACGCTATAAATGTAGCATGTGTGAGAAAAC
CTTCATTAACACCTCATCTCTTCGCAAACATGAGAAAAACCATAGTGGAGAGAAATTATTTAAA
TGTAAAGAATGTTCAAAAGCCTTCAGCCAAAGTTCAGCCCTTATTCAACATCAAATAACTCACA
CTGGAGAGAAGCCTTACGTATGTAAAGAATGTGGGAAGGCCTTCACTCTCAGTACGTCCCTGTA
TAAACATCTCAGAACCCACACTGTGGAGAAATCCTACAGATGTAAGGAATGTGGTAAATCCTTT
GGCCAAAGGTCAGGTCTTTTTATACACCAGAAGATCCATGCCCGAGAAAACCCTCATAGATATA
ACCCAGGAAGGAAGGCATCCGCTTCCCTCTCTGGATGCCAGAGAGCTCATTCCAGGAAGAAGAC
CTACTTGTGTAATGAATGTGGCAACACCTTCAAGTCTAGCTCCTCCCTCCGTTACCATCAGAGA
ATCCACACCGGAGAGAAACCTTTCAGATGTAGCGAATGCGGCAGAGCCTTCAGTCAGAGCGCAT
CACTTATTCAGCACGAAAGAATCCACACGGGAGAAAAGCCCTACAGGTGTGGCGAGTGTGGGAA
AGGCTTCACTTCTATCTCAAGACTCAATAGACACCGGATAATTCATACAGGAGAGAAATTGTAT
AATTGCAATGAGTGTGGCAAAGCCTTAAGTTCCCACTCAACTCTTATTATTCACGAACGAATCC
ACACTGGAGAGAAACCGTGTAAATGTAAAGTTTGTGGGAAAGCCTTCAGACAGAGTTCAGCTCT
GATCCAACATCAGAGAATGCACACTGGGGAAAGACCCTATAAATGTAATGAGTGCGGGAAAACA
TTCAGGTGTAACTCATCCCTAAGTAACCACCAGCGAATCCACACTGGAGAGAAACCTTATCAAT
GTATAGAATGTGGGATGTCGTTTGGACAAAGTTCTGCTCTTATTCAGCACCGAAGGATTCACAC
GGGAGAGAAACCGTTTAAATGTAACACATGCGGAAAGACCTTTAGGCAGAGCTCCTCACGTATA
GCACATCAGCGAATTCATACTGGGGAGAAACCCTACGAATGTAACACGTGTGGGAAACTTTTCA
ACTATAGGTCATCCCTTACCAATCATTATAAAATCCATGTGGATGAGGACCCTTAAAAAGTAAA
TTTGCATGTAAAAAAGCCTTAAACCAAAGCTCTTCAGAGAATGGGCTTGAGAGCTGTAATAAAC
ATACTATGGCGTCCCTGTAGTCATTTAGTTACTGTCAACTAAATTCCATGGATAAATCCTGTGT
AACAGGTAGGAGTGAAATATTCATGCCTGTCCAACACTTTAAAAAAATTGCTTGAAATCCGGTG
GTTATGTGTAGTCCTGGCTACCGGGGACCCTGAGGATTGCTTGACTCCACAAGTTTGAAGAGCA
AATGTTATGGAGCTTTCCATCTCAGAAGATTAGTGACCTGAAATGAAGAATTCACAGCTGAAGG
CCTTGACTTCAGGTATTTGGAAAATGGTGCTTTTCTCTCTGCAACAGTGTGTGCTAGATACAAT
TGTAATCATAGGCATCTAAGTGAACAGAGGAGTGGGATGGACTTAGCAAAACACAAAACTCTAC
TGTTGTGATACTTTTATACTATTTTAATAATATCCAAAAGGGATCAACACAAATCAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_008767660 ⟹ XP_008765882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	35,897,217 - 35,909,059 (+)	NCBI
mRatBN7.2	10	35,396,242 - 35,408,065 (+)	NCBI
Rnor_6.0	10	36,587,889 - 36,600,172 (+)	NCBI

Sequence:

show sequence

GAAAAGAAGTTTAAAGACATTTATTGTTTGTGTATATGAAATGAGTGTGTATGAGCATGGAATG
TATGCACTGACCTGAGATGCCAGAAGGGGATGTTGGAACCCAGGCGCTGCAGTTACAGGCCATT
GTGAGCAACCTGATATGGGTAGTGGGGATTGAACCTAAGTCCTCAGCAAGAACAGTAAGGATTC
TTAACCGCTGAGCACTTCTTCAGTCCTACTAATACCTCATAATAAAGCTCTTCTGAAGGGCACT
TCGTGTCAGCTTCCTTTCCACGAACCTGCGACATCGTTTATTATTTACCTACCAAGCAGGTGTT
CAGTTACTAGTGTCCACTCTCAGCTTCCAAGCAATCTGTGCATAAGAAGAGTCCCAGACAAACC
GAAGAACTTCAAATCCCAGAATCCCTGGGTCTCAGAGTGGACTACATTTCCCAGAGGCCTCCTC
AGTCATTACCCTCGAACCTCAAGTTCTGAGCCCCCGTGAGCCTTCGCGGATCATAGGGAGTCTG
TGGCACCGCTAGAGACTCGGGGCCAAGGTCCTAAGACAGACTTCTCACAGGCGCGGAGGTTCAG
AGCGTATGTGAGGTGCGGCGGGAGCCGGGGAAAAGATCCTCCTCCATCTTCACCCATCTTTAGA
GGAAGAGCCTACAGAAAGAAGATGGCTCCTGAGCAAAGAGAAGGGGCCTCTCAGGTGTCAGTGA
CATTTGAAGATGTGGCTGTGCTCTTTACTCGGGACGAGTGGAAGAAGCTGGATCTGTCTCAGAG
AAGCCTGTACCGTGAGGTGATGCTGGAGAATTACAGCAACCTGGCCTCCATGGGATTCCTGTTT
ACCAAACCAAAGGTGATCTCCCTGTTGCAGCAAGGAGAGGATCCCTGGCAGGTGGAGAAAGAGG
GCCCCAGATACTTCTCTCTCGGATTGAAGTGCAGTCATAGAACCACTAAGTCAACTCAAACACA
AGACTCTTCATTTCAGGAACTGATTGTAAGAAAATCTAAAAGAACCTTTGCCTTCGAACCTTTG
AACATGAAGTCAGAAAATCTTTTCATACATGAAGGCAAATTAGAGGAAAAGTGGGATAAGAATA
CTTTGACTGTAGAAAGAAGCCATAAAAACAATGAATTTAGCCCAAAGTCCCATAGAGAAAAACG
GTCCTCAGAATGTAAAAAGCAGATATCTTATTTATCTAACCCACCAGGAATCACACCGGATAAA
CGCTATAAATGTAGCATGTGTGAGAAAACCTTCATTAACACCTCATCTCTTCGCAAACATGAGA
AAAACCATAGTGGAGAGAAATTATTTAAATGTAAAGAATGTTCAAAAGCCTTCAGCCAAAGTTC
AGCCCTTATTCAACATCAAATAACTCACACTGGAGAGAAGCCTTACGTATGTAAAGAATGTGGG
AAGGCCTTCACTCTCAGTACGTCCCTGTATAAACATCTCAGAACCCACACTGTGGAGAAATCCT
ACAGATGTAAGGAATGTGGTAAATCCTTTGGCCAAAGGTCAGGTCTTTTTATACACCAGAAGAT
CCATGCCCGAGAAAACCCTCATAGATATAACCCAGGAAGGAAGGCATCCGCTTCCCTCTCTGGA
TGCCAGAGAGCTCATTCCAGGAAGAAGACCTACTTGTGTAATGAATGTGGCAACACCTTCAAGT
CTAGCTCCTCCCTCCGTTACCATCAGAGAATCCACACCGGAGAGAAACCTTTCAGATGTAGCGA
ATGCGGCAGAGCCTTCAGTCAGAGCGCATCACTTATTCAGCACGAAAGAATCCACACGGGAGAA
AAGCCCTACAGGTGTGGCGAGTGTGGGAAAGGCTTCACTTCTATCTCAAGACTCAATAGACACC
GGATAATTCATACAGGAGAGAAATTGTATAATTGCAATGAGTGTGGCAAAGCCTTAAGTTCCCA
CTCAACTCTTATTATTCACGAACGAATCCACACTGGAGAGAAACCGTGTAAATGTAAAGTTTGT
GGGAAAGCCTTCAGACAGAGTTCAGCTCTGATCCAACATCAGAGAATGCACACTGGGGAAAGAC
CCTATAAATGTAATGAGTGCGGGAAAACATTCAGGTGTAACTCATCCCTAAGTAACCACCAGCG
AATCCACACTGGAGAGAAACCTTATCAATGTATAGAATGTGGGATGTCGTTTGGACAAAGTTCT
GCTCTTATTCAGCACCGAAGGATTCACACGGGAGAGAAACCGTTTAAATGTAACACATGCGGAA
AGACCTTTAGGCAGAGCTCCTCACGTATAGCACATCAGCGAATTCATACTGGGGAGAAACCCTA
CGAATGTAACACGTGTGGGAAACTTTTCAACTATAGGTCATCCCTTACCAATCATTATAAAATC
CATGTGGATGAGGACCCTTAAAAAGTAAATTTGCATGTAAAAAAGCCTTAAACCAAAGCTCTTC
AGAGAATGGGCTTGAGAGCTGTAATAAACATACTATGGCGTCCCTGTAGTCATTTAGTTACTGT
CAACTAAATTCCATGGATAAATCCTGTGTAACAGGTAGGAGTGAAATATTCATGCCTGTCCAAC
ACTTTAAAAAAATTGCTTGAAATCCGGTGGTTATGTGTAGTCCTGGCTACCGGGGACCCTGAGG
ATTGCTTGACTCCACAAGTTTGAAGAGCAAATGTTATGGAGCTTTCCATCTCAGAAGATTAGTG
ACCTGAAATGAAGAATTCACAGCTGAAGGCCTTGACTTCAGGTATTTGGAAAATGGTGCTTTTC
TCTCTGCAACAGTGTGTGCTAGATACAATTGTAATCATAGGCATCTAAGTGAACAGAGGAGTGG
GATGGACTTAGCAAAACACAAAACTCTACTGTTGTGATACTTTTATACTATTTTAATAATATCC
AAAAGGGATCAACACATTTAAAAAAAAAAGCCGAAATAAAAGATTTAAATGAACTGTAATCTA

hide sequence

RefSeq Acc Id:

XM_039085190 ⟹ XP_038941118

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	35,897,217 - 35,909,059 (+)	NCBI
mRatBN7.2	10	35,396,242 - 35,408,065 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001416828	(Get FASTA)	NCBI Sequence Viewer
	NP_001416829	(Get FASTA)	NCBI Sequence Viewer
	NP_001416830	(Get FASTA)	NCBI Sequence Viewer
	NP_001416831	(Get FASTA)	NCBI Sequence Viewer
	NP_001416832	(Get FASTA)	NCBI Sequence Viewer
	NP_434685	(Get FASTA)	NCBI Sequence Viewer
	XP_008765882	(Get FASTA)	NCBI Sequence Viewer
	XP_038941118	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB07673	(Get FASTA)	NCBI Sequence Viewer
	AAH78777	(Get FASTA)	NCBI Sequence Viewer
	EDM04296	(Get FASTA)	NCBI Sequence Viewer
	EDM04298	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000049437
	ENSRNOP00000070798
	ENSRNOP00000092943
GenBank Protein	Q02975	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_434685 ⟸ NM_052798

- UniProtKB:

Q02975 (UniProtKB/Swiss-Prot), A6HE43 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPEQREGASQVSVTFEDVAVLFTRDEWKKLDLSQRSLYREVMLENYSNLASMAGFLFTKPKVI
SLLQQGEDPWQVEKEGPRYFSLGLKCSHRTTKSTQTQDSSFQELIVRKSKRTFAFEPLNMKSEN
LFIHEGKLEEKWDKNTLTVERSHKNNEFSPKSHREKRSSECKKQISYLSNPPGITPDKRYKCSM
CEKTFINTSSLRKHEKNHSGEKLFKCKECSKAFSQSSALIQHQITHTGEKPYVCKECGKAFTLS
TSLYKHLRTHTVEKSYRCKECGKSFGQRSGLFIHQKIHARENPHRYNPGRKASASLSGCQRAHS
RKKTYLCNECGNTFKSSSSLRYHQRIHTGEKPFRCSECGRAFSQSASLIQHERIHTGEKPYRCG
ECGKGFTSISRLNRHRIIHTGEKLYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQ
SSALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRIHTGEKPYQCIECGMSFGQSSALIQHR
RIHTGEKPFKCNTCGKTFRQSSSRIAHQRIHTGEKPYECNTCGKLFNYRSSLTNHYKIHVDEDP

hide sequence

RefSeq Acc Id:

XP_008765882 ⟸ XM_008767660

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAPEQREGASQVSVTFEDVAVLFTRDEWKKLDLSQRSLYREVMLENYSNLASMGFLFTKPKVIS
LLQQGEDPWQVEKEGPRYFSLGLKCSHRTTKSTQTQDSSFQELIVRKSKRTFAFEPLNMKSENL
FIHEGKLEEKWDKNTLTVERSHKNNEFSPKSHREKRSSECKKQISYLSNPPGITPDKRYKCSMC
EKTFINTSSLRKHEKNHSGEKLFKCKECSKAFSQSSALIQHQITHTGEKPYVCKECGKAFTLST
SLYKHLRTHTVEKSYRCKECGKSFGQRSGLFIHQKIHARENPHRYNPGRKASASLSGCQRAHSR
KKTYLCNECGNTFKSSSSLRYHQRIHTGEKPFRCSECGRAFSQSASLIQHERIHTGEKPYRCGE
CGKGFTSISRLNRHRIIHTGEKLYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQS
SALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRIHTGEKPYQCIECGMSFGQSSALIQHRR
IHTGEKPFKCNTCGKTFRQSSSRIAHQRIHTGEKPYECNTCGKLFNYRSSLTNHYKIHVDEDP

hide sequence

Ensembl Acc Id:

ENSRNOP00000049437 ⟸ ENSRNOT00000045596

Ensembl Acc Id:

ENSRNOP00000070798 ⟸ ENSRNOT00000085203

RefSeq Acc Id:	XP_038941118 ⟸ XM_039085190
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000092943 ⟸ ENSRNOT00000097835

Protein Domains

C2H2-type KRAB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q02975-F1-model_v2	AlphaFold	Q02975	1-576	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2967	AgrOrtholog
BioCyc Gene	G2FUF-25210	BioCyc
Ensembl Genes	ENSRNOG00000003634	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000045596	ENTREZGENE
	ENSRNOT00000085203	ENTREZGENE
	ENSRNOT00000097835	ENTREZGENE
Gene3D-CATH	6.10.140.140	UniProtKB/Swiss-Prot
	Classic Zinc Finger	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7127868	IMAGE-MGC_LOAD
InterPro	KRAB	UniProtKB/Swiss-Prot
	KRAB_dom_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_type	UniProtKB/Swiss-Prot
KEGG Report	rno:24522	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93316	IMAGE-MGC_LOAD
NCBI Gene	24522	ENTREZGENE
PANTHER	ZFP14 ZINC FINGER PROTEIN-RELATED	UniProtKB/Swiss-Prot
	ZINC FINGER AND BTB DOMAIN-CONTAINING	UniProtKB/Swiss-Prot
Pfam	KRAB	UniProtKB/Swiss-Prot
	zf-C2H2	UniProtKB/Swiss-Prot
PhenoGen	Zfp354a	PhenoGen
PROSITE	KRAB	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003634	RatGTEx
SMART	KRAB	UniProtKB/Swiss-Prot
	ZnF_C2H2	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF109640	UniProtKB/Swiss-Prot
	SSF57667	UniProtKB/Swiss-Prot
UniProt	A0A0G2JYU9_RAT	UniProtKB/TrEMBL
	A0A8I6AIY2_RAT	UniProtKB/TrEMBL
	A0A8L2QNR3	ENTREZGENE, UniProtKB/TrEMBL
	A6HE43	ENTREZGENE, UniProtKB/TrEMBL
	Q02975	ENTREZGENE
	Q6AZ27	ENTREZGENE, UniProtKB/TrEMBL
	Z354A_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Zfp354a	zinc finger protein 354A			Symbol updated	1299863	APPROVED
2002-02-20	Znf354a	zinc finger protein 354A			Symbol and Name updated to reflect Human and Mouse nomenclature	70282	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed predominantly in the kidney	1300202
gene_expression	mRNA accumulates with age in postnatal renal development	1300202

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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