Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dpm2 | Rat | congenital disorder of glycosylation Iu | | ISO | DPM2 (Homo sapiens) | 7240710 | | OMIM | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dpm2 | Rat | congenital disorder of glycosylation Iu | | ISO | DPM2 (Homo sapiens) | 7240710 | | OMIM | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. | Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 3. | DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate. | Maeda Y, etal., EMBO J 1998 Sep 1;17(17):4920-9. |
| 4. | Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3. | Maeda Y, etal., EMBO J. 2000 Jun 1;19(11):2475-82. |
| 5. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 6. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 7. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
| 8. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 9. | GOA pipeline | RGD automated data pipeline |
| 10. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 11. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 12. | Tentative Sequence Identification Numbers | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
| Dpm2 (Rattus norvegicus - Norway rat) |
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| DPM2 (Homo sapiens - human) |
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| Dpm2 (Mus musculus - house mouse) |
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| Dpm2 (Chinchilla lanigera - long-tailed chinchilla) |
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| DPM2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DPM2 (Canis lupus familiaris - dog) |
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| Dpm2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DPM2 (Sus scrofa - pig) |
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| DPM2 (Chlorocebus sabaeus - green monkey) |
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| Dpm2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Dpm2
11 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| RH133303 |
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| RH142191 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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| 16 | 12 | 67 | 163 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 142 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_019252 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_063283414 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063283415 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AB013359 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| BC070512 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474001 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000003 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000071505 ⟹ ENSRNOP00000065111 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000109105 ⟹ ENSRNOP00000092836 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_019252 ⟹ NP_062125 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_063283414 ⟹ XP_063139484 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063283415 ⟹ XP_063139485 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_062125 | (Get FASTA) | NCBI Sequence Viewer |
| XP_063139484 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063139485 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | BAA33972 | (Get FASTA) | NCBI Sequence Viewer |
| EDL93229 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000104528 | ||
| GenBank Protein | Q9Z325 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_062125 ⟸ NM_019252 |
| - UniProtKB: | Q9Z325 (UniProtKB/Swiss-Prot), A0A8I6AHS9 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000065111 ⟸ ENSRNOT00000071505 |
| Ensembl Acc Id: | ENSRNOP00000092836 ⟸ ENSRNOT00000109105 |
| RefSeq Acc Id: | XP_063139484 ⟸ XM_063283414 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063139485 ⟸ XM_063283415 |
| - Peptide Label: | isoform X2 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-Q9Z325-F1-model_v2 | AlphaFold | Q9Z325 | 1-84 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:2514 | AgrOrtholog |
| BioCyc Gene | G2FUF-50133 | BioCyc |
| Ensembl Genes | ENSRNOG00000049110 | Ensembl |
| ENSRNOG00000070298 | Ensembl | |
| ENSRNOG00000084654 | ENTREZGENE | |
| Ensembl Transcript | ENSRNOT00000131121 | ENTREZGENE |
| IMAGE_CLONE | IMAGE:7096306 | IMAGE-MGC_LOAD |
| InterPro | DPM2 | UniProtKB/Swiss-Prot |
| KEGG Report | rno:29640 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:91720 | IMAGE-MGC_LOAD |
| NCBI Gene | 29640 | ENTREZGENE |
| PANTHER | DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN | UniProtKB/Swiss-Prot |
| PTHR15039 | UniProtKB/Swiss-Prot | |
| Pfam | DPM2 | UniProtKB/Swiss-Prot |
| PhenoGen | Dpm2 | PhenoGen |
| RatGTEx | ENSRNOG00000049110 | RatGTEx |
| ENSRNOG00000070298 | RatGTEx | |
| ENSRNOG00000084654 | RatGTEx | |
| TIGR | TC217775 | |
| UniProt | A0A8I6AHS9 | ENTREZGENE, UniProtKB/TrEMBL |
| A0ABK0L5H1_RAT | UniProtKB/TrEMBL | |
| A0ABK0L6M0_RAT | UniProtKB/TrEMBL | |
| A6JU68_RAT | UniProtKB/TrEMBL | |
| DPM2_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2022-06-02 | Dpm2 | dolichyl-phosphate mannosyltransferase subunit 2, regulatory | ENSRNOG00000070298 | Data merged from RGD:150343128 | 737654 | PROVISIONAL | |
| 2021-08-31 | ENSRNOG00000070298 | Symbol and Name status set to provisional | 45752 | PROVISIONAL | |||
| 2016-07-27 | Dpm2 | dolichyl-phosphate mannosyltransferase subunit 2, regulatory | Dpm2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-11-11 | Dpm2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | Dpm2 | dolichol-phosphate (beta-D) mannosyltransferase 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-11-17 | Dpm2 | dolichol-phosphate (beta-D) mannosyltransferase 2 | dolichol-phosphate mannosyltransferase 2 | Name updated | 1299863 | APPROVED | |
| 2002-06-10 | Dpm2 | dolichol-phosphate mannosyltransferase 2 | Name updated | 70584 | APPROVED |
| Note Type | Note | Reference |
|---|---|---|
| gene_expression | expressed in ER membrane | 69827 |
| gene_physical_interaction | binds to DPM1 | 69827 |
| gene_process | essential for the ER membrane localization and the stable protein expression of DPM1 | 69827 |
| gene_process | regulates biosynthesis of dolichol phosphate-mannose (DPM) | 69827 |
| gene_protein | enhances binding of dolichol phosphate (Dol-P) to DPM synthase | 69827 |