Gene: Eif4ebp3 (eukaryotic translation initiation factor 4E binding protein 3) Rattus norvegicus
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Symbol:
Eif4ebp3 (Ensembl: Ankhd1)
Name:
eukaryotic translation initiation factor 4E binding protein 3 (Ensembl:ankyrin repeat and KH domain containing 1)
RGD ID:
2324556
Description:
Predicted to be involved in innate immune response. Predicted to be active in cytoplasm. Orthologous to several human genes including ANKHD1-EIF4EBP3 (ANKHD1-EIF4EBP3 readthrough) and ANKHD1 (ankyrin repeat and KH domain containing 1); INTERACTS WITH 17beta-estradiol; bisphenol A; chlorohydrocarbon.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
eukaryotic translation initiation factor 4E binding protein 3-like; eukaryotic translation initiation factor 4E-binding protein 3; LOC100365872
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 18 28,540,324 - 28,542,070 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 18 28,540,058 - 28,542,061 (+) Ensembl GRCr8 mRatBN7.2 18 28,263,089 - 28,268,033 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 18 28,162,311 - 28,268,024 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 18 28,393,432 - 28,395,178 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 18 29,155,523 - 29,157,269 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 18 28,490,761 - 28,492,507 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 18 28,757,969 - 28,759,715 (+) NCBI Dahl_SR_JrHsd Lyon_Normotensive 18 28,341,190 - 28,342,936 (+) NCBI Lyon_Normotensive Lyon_Hypertensive 18 28,355,429 - 28,357,175 (+) NCBI Lyon_Hypertensive F344_StmMcwi 18 28,399,373 - 28,401,119 (+) NCBI F344_StmMcwi Rnor_6.0 18 29,490,981 - 29,492,727 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 18 29,386,809 - 29,492,718 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 18 29,196,055 - 29,197,801 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 Celera 18 27,993,461 - 27,995,207 (+) NCBI Celera Cytogenetic Map 18 p11 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Eif4ebp3 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Eif4ebp3 Rat 1,2-dimethylhydrazine multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4EBP3 mRNA CTD PMID:22206623 Eif4ebp3 Rat 1,2-dimethylhydrazine decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of EIF4EBP3 mRNA CTD PMID:22206623 Eif4ebp3 Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of EIF4EBP3 mRNA CTD PMID:32145629 Eif4ebp3 Rat 17beta-estradiol increases expression ISO Eif4ebp3 (Mus musculus) 6480464 Estradiol results in increased expression of EIF4EBP3 mRNA CTD PMID:39298647 Eif4ebp3 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Eif4ebp3 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Eif4ebp3 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Eif4ebp3 Rat 4,4'-sulfonyldiphenol increases expression ISO Eif4ebp3 (Mus musculus) 6480464 bisphenol S results in increased expression of EIF4EBP3 mRNA CTD PMID:39298647 Eif4ebp3 Rat arachidonic acid multiple interactions ISO EIF4EBP3 (Homo sapiens) 6480464 Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of EIF4EBP3 protein] CTD PMID:20551291 Eif4ebp3 Rat arsenite(3-) increases methylation ISO EIF4EBP3 (Homo sapiens) 6480464 arsenite results in increased methylation of EIF4EBP3 promoter CTD PMID:23974009 Eif4ebp3 Rat atrazine increases expression ISO EIF4EBP3 (Homo sapiens) 6480464 Atrazine results in increased expression of EIF4EBP3 mRNA CTD PMID:22378314 Eif4ebp3 Rat benzo[a]pyrene increases methylation ISO EIF4EBP3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of EIF4EBP3 exon; Benzo(a)pyrene results in increased methylation of EIF4EBP3 more ... CTD PMID:27901495 Eif4ebp3 Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of EIF4EBP3 mRNA] CTD PMID:19850644 Eif4ebp3 Rat bis(2-ethylhexyl) phthalate increases phosphorylation ISO EIF4EBP3 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of EIF4EBP3 protein CTD PMID:31163220 Eif4ebp3 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of EIF4EBP3 mRNA CTD PMID:19850644 Eif4ebp3 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EIF4EBP3 mRNA CTD PMID:25181051 Eif4ebp3 Rat bisphenol A decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 bisphenol A results in decreased expression of EIF4EBP3 mRNA CTD PMID:32156529 Eif4ebp3 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EIF4EBP3 mRNA CTD PMID:32145629 Eif4ebp3 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EIF4EBP3 mRNA CTD PMID:30903817 Eif4ebp3 Rat Bisphenol Z increases expression ISO EIF4EBP3 (Homo sapiens) 6480464 bisphenol Z results in increased expression of EIF4EBP3 mRNA CTD PMID:32387340 Eif4ebp3 Rat cadmium atom multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of EIF4EBP3 more ... CTD PMID:37236586 Eif4ebp3 Rat cadmium dichloride decreases expression ISO EIF4EBP3 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of EIF4EBP3 mRNA CTD PMID:38568856 Eif4ebp3 Rat cadmium dichloride multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of EIF4EBP3 more ... CTD PMID:37236586 Eif4ebp3 Rat carbon nanotube increases expression ISO Eif4ebp3 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of EIF4EBP3 mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25620056 Eif4ebp3 Rat chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of more ... CTD PMID:30744511 Eif4ebp3 Rat chlorpyrifos decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of EIF4EBP3 mRNA CTD PMID:37019170 Eif4ebp3 Rat chrysene increases expression ISO Eif4ebp3 (Mus musculus) 6480464 chrysene results in increased expression of EIF4EBP3 mRNA CTD PMID:26377693 Eif4ebp3 Rat ciguatoxin CTX1B affects expression ISO Eif4ebp3 (Mus musculus) 6480464 Ciguatoxins affects the expression of EIF4EBP3 mRNA CTD PMID:18353800 Eif4ebp3 Rat Dibutyl phosphate affects expression ISO EIF4EBP3 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of EIF4EBP3 mRNA CTD PMID:37042841 Eif4ebp3 Rat dichloroacetic acid decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 Dichloroacetic Acid results in decreased expression of EIF4EBP3 mRNA CTD PMID:28962523 Eif4ebp3 Rat diquat increases expression ISO Eif4ebp3 (Mus musculus) 6480464 Diquat results in increased expression of EIF4EBP3 mRNA CTD PMID:36851058 Eif4ebp3 Rat folic acid multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4EBP3 mRNA CTD PMID:22206623 Eif4ebp3 Rat FR900359 increases phosphorylation ISO EIF4EBP3 (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of EIF4EBP3 protein CTD PMID:37730182 Eif4ebp3 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of EIF4EBP3 mRNA CTD PMID:33387578 Eif4ebp3 Rat gold atom multiple interactions ISO EIF4EBP3 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein CTD PMID:27470402 Eif4ebp3 Rat gold(0) multiple interactions ISO EIF4EBP3 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein CTD PMID:27470402 Eif4ebp3 Rat graphene oxide increases expression ISO Eif4ebp3 (Mus musculus) 6480464 graphene oxide results in increased expression of EIF4EBP3 mRNA CTD PMID:33227293 Eif4ebp3 Rat methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of EIF4EBP3 mRNA CTD PMID:30467583 Eif4ebp3 Rat methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of more ... CTD PMID:30744511 Eif4ebp3 Rat PCB138 multiple interactions ISO Eif4ebp3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Eif4ebp3 Rat perfluorononanoic acid increases expression ISO EIF4EBP3 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of EIF4EBP3 mRNA CTD PMID:32588087 Eif4ebp3 Rat pirinixic acid decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 pirinixic acid results in decreased expression of EIF4EBP3 mRNA CTD PMID:20813756 Eif4ebp3 Rat pregnenolone 16alpha-carbonitrile increases expression ISO Eif4ebp3 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of EIF4EBP3 mRNA CTD PMID:28903501 Eif4ebp3 Rat quercetin multiple interactions ISO EIF4EBP3 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein; Arachidonic Acid more ... CTD PMID:20551291|PMID:27470402 Eif4ebp3 Rat quercetin decreases phosphorylation ISO EIF4EBP3 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of EIF4EBP3 protein CTD PMID:20551291 Eif4ebp3 Rat sodium arsenite decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 sodium arsenite results in decreased expression of EIF4EBP3 mRNA CTD PMID:37682722 Eif4ebp3 Rat sunitinib increases expression ISO EIF4EBP3 (Homo sapiens) 6480464 Sunitinib results in increased expression of EIF4EBP3 mRNA CTD PMID:31533062 Eif4ebp3 Rat tetrachloromethane affects expression ISO Eif4ebp3 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of EIF4EBP3 mRNA CTD PMID:31919559 Eif4ebp3 Rat thiram decreases expression ISO EIF4EBP3 (Homo sapiens) 6480464 Thiram results in decreased expression of EIF4EBP3 mRNA CTD PMID:38568856 Eif4ebp3 Rat triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of EIF4EBP3 mRNA CTD PMID:30589522 Eif4ebp3 Rat triphenyl phosphate affects expression ISO EIF4EBP3 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of EIF4EBP3 mRNA CTD PMID:37042841 Eif4ebp3 Rat Triptolide decreases expression ISO Eif4ebp3 (Mus musculus) 6480464 triptolide results in decreased expression of EIF4EBP3 mRNA CTD PMID:32835833 Eif4ebp3 Rat urethane increases expression ISO EIF4EBP3 (Homo sapiens) 6480464 Urethane results in increased expression of EIF4EBP3 mRNA CTD PMID:28818685 Eif4ebp3 Rat valproic acid increases expression ISO EIF4EBP3 (Homo sapiens) 6480464 Valproic Acid results in increased expression of EIF4EBP3 mRNA CTD PMID:19101580