Baat (bile acid CoA:amino acid N-acyltransferase) - Rat Genome Database

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Gene: Baat (bile acid CoA:amino acid N-acyltransferase) Rattus norvegicus
Analyze
Symbol: Baat
Name: bile acid CoA:amino acid N-acyltransferase
RGD ID: 2190
Description: Enables glycine N-choloyltransferase activity. Involved in animal organ regeneration; bile acid conjugation; and liver development. Located in cytosol and peroxisome. Human ortholog(s) of this gene implicated in disease of metabolism. Orthologous to human BAAT (bile acid-CoA:amino acid N-acyltransferase); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BACAT; BAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid-CoA thioesterase; bile acid-CoA:amino acid N-acyltransferase; bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase; bile acid-Coenzyme A: amino acid N-acyltransferase; choloyl-CoA hydrolase; glycine N-choloyltransferase; kan-1; long-chain fatty-acyl-CoA hydrolase; MGC108728
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8568,647,166 - 68,656,137 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl568,646,203 - 68,656,181 (-)EnsemblGRCr8
mRatBN7.2563,851,668 - 63,860,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl563,850,705 - 63,860,685 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx565,782,410 - 65,791,367 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0567,601,742 - 67,610,699 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0567,571,122 - 67,580,079 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0564,768,397 - 64,777,368 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl564,768,401 - 64,777,368 (-)Ensemblrn6Rnor6.0
Rnor_5.0569,259,739 - 69,268,710 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4566,245,786 - 66,254,757 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera563,747,341 - 63,756,312 (+)NCBICelera
RGSC_v3.1566,250,741 - 66,259,885 (-)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-chloropropane-1,2-diol  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
8-Epidiosbulbin E acetate  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
atazanavir sulfate  (ISO)
Azoxymethane  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
ciprofibrate  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
deoxycholic acid  (ISO)
dextran sulfate  (ISO)
dibenzofurans  (ISO)
dicrotophos  (ISO)
Diosbulbin B  (ISO)
doxorubicin  (EXP)
endosulfan  (EXP)
flavonoids  (EXP)
flutamide  (EXP)
furan  (EXP)
glafenine  (EXP)
glucose  (ISO)
glycidol  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
GW 4064  (ISO)
imipenem hydrate  (ISO)
indometacin  (EXP)
L-ethionine  (EXP)
lead diacetate  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
lithocholic acid  (ISO)
metacetamol  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nefazodone  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorododecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
quercetin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
senecionine  (EXP,ISO)
sevoflurane  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
streptozocin  (ISO)
tartrazine  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vitamin E  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IDA,IEA,ISO)
peroxisome  (IBA,IDA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Carlton VE, etal., Nat Genet 2003 May;34(1):91-6.
2. Reduced expression of kan-1 (encoding putative bile acid-CoA-amino acid N-acyltransferase) mRNA in livers of rats after partial hepatectomy and during sepsis. Furutani M, etal., Biochem J 1995 Oct 1;311 ( Pt 1):203-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat liver bile acid CoA:amino acid N-acyltransferase: expression, characterization, and peroxisomal localization. He D, etal., J Lipid Res. 2003 Dec;44(12):2242-9. Epub 2003 Sep 1.
6. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
7. Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from rat liver. Killenberg PG and Jordan JT, J Biol Chem. 1978 Feb 25;253(4):1005-10.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: Implications for intracellular bile salt transport. Pellicoro A, etal., Hepatology. 2007 Jan 26;45(2):340-348.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:2037576   PMID:8034703   PMID:9215542   PMID:12239217   PMID:12477932   PMID:12810727   PMID:15489334   PMID:17483744   PMID:19008781   PMID:20178365  


Genomics

Comparative Map Data
Baat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8568,647,166 - 68,656,137 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl568,646,203 - 68,656,181 (-)EnsemblGRCr8
mRatBN7.2563,851,668 - 63,860,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl563,850,705 - 63,860,685 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx565,782,410 - 65,791,367 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0567,601,742 - 67,610,699 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0567,571,122 - 67,580,079 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0564,768,397 - 64,777,368 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl564,768,401 - 64,777,368 (-)Ensemblrn6Rnor6.0
Rnor_5.0569,259,739 - 69,268,710 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4566,245,786 - 66,254,757 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera563,747,341 - 63,756,312 (+)NCBICelera
RGSC_v3.1566,250,741 - 66,259,885 (-)NCBI
Cytogenetic Map5q22NCBI
BAAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389101,360,417 - 101,385,006 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9101,354,182 - 101,385,400 (-)Ensemblhg38GRCh38
GRCh379104,122,699 - 104,147,288 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369103,162,890 - 103,187,108 (-)NCBIBuild 36Build 36hg18NCBI36
Build 349101,202,623 - 101,226,842NCBI
Celera974,636,308 - 74,660,897 (-)NCBICelera
Cytogenetic Map9q31.1NCBI
HuRef973,722,155 - 73,746,742 (-)NCBIHuRef
CHM1_19104,269,127 - 104,293,716 (-)NCBICHM1_1
T2T-CHM13v2.09113,532,396 - 113,556,986 (-)NCBIT2T-CHM13v2.0
Baat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39449,489,416 - 49,507,915 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl449,489,422 - 49,506,557 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38449,489,416 - 49,507,915 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl449,489,422 - 49,506,557 (-)Ensemblmm10GRCm38
MGSCv37449,502,290 - 49,519,430 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36449,510,518 - 49,527,564 (-)NCBIMGSCv36mm8
Celera449,518,587 - 49,535,626 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.51NCBI
Baat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541924,443,172 - 24,520,467 (+)Ensembl
ChiLan1.0NW_00495541924,469,213 - 24,521,728 (+)NCBIChiLan1.0ChiLan1.0
BAAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21137,988,783 - 38,004,070 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1937,991,151 - 38,006,443 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0972,568,002 - 72,593,179 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19100,563,040 - 100,587,634 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9100,563,040 - 100,586,189 (-)EnsemblpanPan2panpan1.1
BAAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11158,102,057 - 58,116,750 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1158,102,592 - 58,109,389 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1156,546,290 - 56,560,084 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01159,237,323 - 59,251,117 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1159,237,858 - 59,244,608 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11157,747,129 - 57,760,914 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01157,760,194 - 57,775,214 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01158,458,799 - 58,472,591 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Baat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947172,975,664 - 173,016,805 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365249,536,010 - 9,545,076 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365249,536,032 - 9,544,901 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110255172
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11243,033,379 - 243,039,795 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
BAAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11238,055,100 - 38,082,969 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1238,073,329 - 38,081,927 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660354,470,691 - 4,501,686 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Baat
78 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:267
Interacting mature miRNAs:319
Transcripts:ENSRNOT00000009777
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 10 50 125 91 90 59 69 59 6 307 147 8 106 80 84 31 3 3

Sequence


Ensembl Acc Id: ENSRNOT00000009777   ⟹   ENSRNOP00000009777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl568,646,203 - 68,656,181 (-)Ensembl
mRatBN7.2 Ensembl563,850,705 - 63,860,685 (-)Ensembl
Rnor_6.0 Ensembl564,768,401 - 64,777,368 (-)Ensembl
RefSeq Acc Id: NM_017300   ⟹   NP_058996
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8568,647,166 - 68,656,137 (-)NCBI
mRatBN7.2563,851,668 - 63,860,641 (-)NCBI
Rnor_6.0564,768,397 - 64,777,368 (-)NCBI
Rnor_5.0569,259,739 - 69,268,710 (-)NCBI
RGSC_v3.4566,245,786 - 66,254,757 (-)RGD
Celera563,747,341 - 63,756,312 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058996 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88153 (Get FASTA)   NCBI Sequence Viewer  
  BAA07901 (Get FASTA)   NCBI Sequence Viewer  
  EDL78183 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009777
  ENSRNOP00000009777.2
GenBank Protein Q63276 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058996   ⟸   NM_017300
- UniProtKB: Q5M8A2 (UniProtKB/Swiss-Prot),   Q63276 (UniProtKB/Swiss-Prot),   A6KJE5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009777   ⟸   ENSRNOT00000009777
Protein Domains
Acyl-CoA thioester hydrolase/bile acid-CoA amino   BAAT/Acyl-CoA thioester hydrolase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63276-F1-model_v2 AlphaFold Q63276 1-420 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693728
Promoter ID:EPDNEW_R4253
Type:initiation region
Name:Baat_1
Description:bile acid CoA:amino acid N-acyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0564,777,383 - 64,777,443EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2190 AgrOrtholog
BioCyc Gene G2FUF-41329 BioCyc
BioCyc Pathway PWY-6061 [bile acid biosynthesis, neutral pathway] BioCyc
BioCyc Pathway Image PWY-6061 BioCyc
Ensembl Genes ENSRNOG00000007395 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009777 ENTREZGENE
  ENSRNOT00000009777.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.2240 UniProtKB/Swiss-Prot
  3.40.50.1820 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7368634 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot
  Acyl-CoA_thioEstase_long-chain UniProtKB/Swiss-Prot
  BAAT_C UniProtKB/Swiss-Prot
  Thio_Ohase/aa_AcTrfase UniProtKB/Swiss-Prot
  Thio_Ohase/BAAT_N UniProtKB/Swiss-Prot
KEGG Report rno:29725 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108728 IMAGE-MGC_LOAD
NCBI Gene 29725 ENTREZGENE
PANTHER ACYL-COENZYME A THIOESTERASE-RELATED UniProtKB/Swiss-Prot
  BILE ACID-COA:AMINO ACID N-ACYLTRANSFERASE UniProtKB/Swiss-Prot
Pfam BAAT_C UniProtKB/Swiss-Prot
  Bile_Hydr_Trans UniProtKB/Swiss-Prot
PhenoGen Baat PhenoGen
PIRSF Acyl-CoA_hydro UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007395 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot
TIGR TC238703
UniProt A6KJE5 ENTREZGENE, UniProtKB/TrEMBL
  BAAT_RAT UniProtKB/Swiss-Prot
  Q5M8A2 ENTREZGENE
  Q63276 ENTREZGENE
UniProt Secondary Q5M8A2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-09 Baat  bile acid CoA:amino acid N-acyltransferase  Baat  bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-28 Baat  bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)  Baat  bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Baat  bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)  Baat  bile acid-Coenzyme A: amino acid N-acyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Baat  bile acid-Coenzyme A: amino acid N-acyltransferase      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in hepatocytes, sinusoidal endothelial cells and the Kupffer cells of the liver 69770
gene_process may play a role in acute-phase reactions 69770
gene_protein 420 amino acids 69770