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Gene: Nxph2 (neurexophilin 2) Rattus norvegicus

Analyze

Symbol:

Nxph2

Name:

neurexophilin 2

RGD ID:

1598138

Description:

Predicted to enable signaling receptor binding activity. Predicted to be located in extracellular region. Orthologous to human NXPH2 (neurexophilin 2); INTERACTS WITH bisphenol A; 2,2',5,5'-tetrachlorobiphenyl (ortholog); acrylamide (ortholog).

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC679932; neurexophilin-2; similar to neurexophilin 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NXPH2 (neurexophilin 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nxph2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nxph2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NXPH2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NXPH2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nxph2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NXPH2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NXPH2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nxph2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Nxph2 (neurexophilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TAF5L (TATA-box binding protein associated factor 5 like)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Nxph2 (neurexophilin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nxph2 (neurexophilin 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NXPH2 (neurexophilin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Homo sapiens (human):	NXPH2 (neurexophilin 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nxph2b (neurexophilin 2b)	Alliance	DIOPT (OMA\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	nxph2a (neurexophilin 2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nxph2a (neurexophilin 2a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nxph2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nxph2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	26,373,858 - 26,392,392 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	26,153,756 - 26,391,876 (+)	Ensembl				GRCr8
mRatBN7.2	3	5,986,175 - 5,988,525 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	5,756,621 - 5,987,008 (+)	Ensembl				mRatBN7.2
Rnor_6.0	3	67,027 - 309,536 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	307,204 - 307,980 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	287,673 - 305,404 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	1,389,458 - 1,425,644 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	588,303 - 827,274 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ovarian cyst (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',5,5'-tetrachlorobiphenyl (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenous acid (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

clothianidin (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

fenamidone (ISO)

fulvestrant (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

niclosamide (ISO)

phenylmercury acetate (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sunitinib (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

extracellular region (IEA)

Molecular Function

signaling receptor binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Nxph2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	26,373,858 - 26,392,392 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	26,153,756 - 26,391,876 (+)	Ensembl				GRCr8
mRatBN7.2	3	5,986,175 - 5,988,525 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	5,756,621 - 5,987,008 (+)	Ensembl				mRatBN7.2
Rnor_6.0	3	67,027 - 309,536 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	307,204 - 307,980 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	287,673 - 305,404 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	1,389,458 - 1,425,644 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	588,303 - 827,274 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

NXPH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	138,669,157 - 138,780,390 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	138,669,157 - 138,780,390 (-)	Ensembl			hg38	GRCh38
GRCh37	2	139,426,727 - 139,537,960 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	139,144,921 - 139,254,281 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	139,262,182 - 139,371,543	NCBI
Celera	2	133,138,346 - 133,249,419 (-)	NCBI		Celera
Cytogenetic Map	2	q22.1	NCBI
HuRef	2	131,418,025 - 131,528,441 (-)	NCBI		HuRef
CHM1_1	2	139,431,333 - 139,542,431 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	139,114,820 - 139,226,050 (-)	NCBI		T2T-CHM13v2.0

Nxph2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	23,211,258 - 23,291,998 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	23,211,258 - 23,291,985 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	23,321,246 - 23,401,986 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	23,321,246 - 23,401,973 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	23,176,766 - 23,257,493 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	23,143,255 - 23,223,982 (+)	NCBI		MGSCv36	mm8
Celera	2	23,053,318 - 23,134,200 (+)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	15.28	NCBI

Nxph2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	5,699,352 - 5,700,095 (-)	Ensembl
ChiLan1.0	NW_004955440	5,697,702 - 5,700,095 (-)	NCBI	ChiLan1.0	ChiLan1.0

NXPH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	36,145,494 - 36,262,803 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	36,160,460 - 36,272,428 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	21,071,974 - 21,184,767 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	142,743,932 - 142,855,893 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	142,745,699 - 142,751,017 (-)	Ensembl			panPan2	panpan1.1

NXPH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	41,316,391 - 41,321,165 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	41,318,149 - 41,318,904 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	41,569,643 - 41,679,428 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	42,753,113 - 42,862,679 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	42,753,798 - 42,862,858 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	41,414,481 - 41,524,828 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	41,563,886 - 41,673,853 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	42,789,176 - 42,899,197 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nxph2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	104,108,224 - 104,215,767 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	37,402,858 - 37,509,500 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	37,402,071 - 37,509,488 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NXPH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	12,953,195 - 13,073,202 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	12,953,062 - 13,073,208 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	15,096,481 - 15,217,114 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NXPH2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	24,032,797 - 24,145,279 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	24,032,902 - 24,145,130 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	175,201,804 - 175,314,359 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nxph2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	38,433,156 - 38,560,534 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624732	38,433,202 - 38,560,449 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nxph2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	109,760,013 - 109,783,815 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nxph2
191 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	22
Count of miRNA genes:	21
Interacting mature miRNAs:	22
Transcripts:	ENSRNOT00000062080
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450811	Scl73	Serum cholesterol level QTL 73	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat
10450808	Scl72	Serum cholesterol level QTL 72	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
10450806	Scl71	Serum cholesterol level QTL 71	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	6125437	51125437	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	36721849	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	6556347	51556347	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	18	96	12	13	11	1	11	44	19	97	7	35	2	7	7

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008761617	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000062080 ⟹ ENSRNOP00000058783

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	26,311,263 - 26,391,876 (+)	Ensembl
mRatBN7.2 Ensembl	3	5,756,621 - 5,987,008 (+)	Ensembl
Rnor_6.0 Ensembl	3	307,204 - 307,980 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000141026 ⟹ ENSRNOP00000110516

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	26,153,756 - 26,391,876 (+)	Ensembl

RefSeq Acc Id:

XM_008761617 ⟹ XP_008759839

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	26,373,858 - 26,392,392 (+)	NCBI
mRatBN7.2	3	5,986,175 - 5,988,525 (+)	NCBI
Rnor_6.0	3	67,027 - 309,536 (+)	NCBI

Sequence:

show sequence

ACTCTGTGCAAAGCTCCTGAATGAGAGCCTCTAGCTGTGCTGTCGCGATAGTGGTTCCCCAGCC
CTCAAATCCTCGGGCCCCTAGCTGCTCACAACAGAGGCAAGGGGCAGCCTGAGGGAGTGTACTG
AAGTCCTGCTGCGGAGAACGTGGACCACACCTCCTTCCCGCTCCTGCTTCTCGACTCTCTGTCC
ACTGGCCTCTGGGTACCAAACCTCCTCAGCCTTCACCCCAAGTGGAGATGCTCAAGATGCTGGT
AAGGGAGCTCAGCTCCTGAGATCGCGCCAGCTGGCACGATGAGCTTGCGGCCGCTGCCTCTCCT
TGTAGTTCCTGGCTTGCTGCAGCTGCTATTCTGTGACAGTGAAAAAGTGATACGTACCTCAGAG
AGTGTGGACTGGGAAGACAGAACTGTTCCTGGAACGTTGGTTAGAAATGTGGTACATTCAAGGA
TTACCAGTCCTGTGCATCTCTTTGTTAAACAGCCTCTGGGTTCAAAGCCAGCATATGCAGACAA
TTTGGAAAACTTTGGGGATTGGCTGGCAAACAGAACAGAGATTCAAGAGCCACTAGCAAGAACT
AAAAGACGGCCAATAGTGAAGACAGGAAAATTTAAGAAAATGTTTGGGTGGGGTGACTTCCATT
CTAACATTAAAACTGTCAAACTTAACCTGCTCATCACAGGAAAAATTGTTGATCATGGAAATGG
AACATTTAGTGTTTATTTCCGGCACAATTCAACAGGCCTGGGCAATGTTTCAGTGAGCTTGGTA
CCTCCCTCTAAAATAGTAGAATTTGAAGTGTCCACCCAGTCTTCCTTGGAGACTAAGGAATCCA
AATCTTTTAACTGCCATATTGAGTATGAAAAAACAGATCGGGCAAAGAAGACTGCTTTGTGCAA
TTTTGACCCATCCAAAATCTGTTACCAGGAGCAGACTCAAAGTCATGTGTCCTGGTTATGTTCC
AAACCATTTAAAGTCATCTGCATTCACATTGCCTTTTACAGTATTGATTATAAACTTGTACAAA
AGGTTTGTCCTGACTACAATTACCATAGTGAGACACCATACTTAACTTCTGGATAAATCTTTTC
TCAGTAATAGAAATGAAATTTTCATGTCAATTTACCTAGAATGCCAATAAAACAGGCCCAGCTT
TCCCTGACAAAAGACCCTTCTATTTCTGGCAATAGACTGTAATTACTTGTCCATATTTCACATT
AAAATATATATTCAAATGAGAAGTTGATTTATTTTGGTGATATTATCCTTATCTAAAAAGTTAA
ACAGATTGTAAAAAACCATCATTTTCATGTAAGATGGTAACATTCTGGAAATGTTGCTTCTCTG
TAAGAAGCATCAGCAGTAGCCATGTGTAAAAGGAGGAACCAAATTGTGCATGTGATAAGCACTG
TTCTTCAAACAGTTCAATTGTGCATGTGATGAGCCTGTCTTTGATGTGTTTTAGAAAGTTTCAA
AGAGTAGGTTCAGTAAAATAATTGAGAAGATGGTGTTTAAGAGATGGATTGTGTTTCTGGTATT
GAACTGTTTTTTAAAATTACTATCTCTTGATGTCAATTTTAATAGCTACAATGTCACAAGAAAA
TCAAACACAATACTATCTGAGCAGTCTGCATAGACAATGATTGAAGCACTTTACTATTATGATT
CTCATTTGAGTGGTATTGAAACATACCACTTGGGTACTAGATAAGCAAATGTAGGTGTAAGTCA
ACTCAACAATAATGAAGATGATATTTGTAGACACTTCAGTGTTGCAGATTCTTTTTTTTAATTC
TTATTCACATTAAAGTAAGGACTTCAGTCCCATTATTTGATAGTCTGATTTTATATATACATTT
GTGGAACAATTCTGAAATTGAAAGAAAGTATTTCTGGGCAAAACCATTCCACAGTCATGGACTC
ATTATTTGTAGGCCCTCAGATTAGGTTTTCTTTGCATTTGTTATCACCAAAATGAGAATAAGAG
TTCTATGTAGAAATAATTAGTTACATTTGAGTATTTCTAAAAAATAAGTACTGATATTTACAAT
GCCTGTATCACTGACATTTTGAGATTACTTTACTCTCAGTGTCCTCATCTTCGAGAAGAGTTGA
ATGACCATCTTTAGGATGGGTAATGAGACTGAATGAGAACAGATAAAGGGAAGAAGACTGGTAG
GACTCGAGACTTGTAGTTAGTCTCCTCTAATAGATATTAACTTCTACTTAAATACTCATCTGTA
CAGTGTTAAACAAGTAAAATACTTAAATAGGACTCATTTAAGGTAAGTCCTAACCAACAAATGT
ACTCTTATCACATTGTTCAGAAAGCCTACAGCTTTGTTCTGTACTTTACATCTCTATTCTGTCC
TTTTCCTGGAAATACTTATTGTGTCTTACTTTGTCTTTTGTACAAGTTGTGCTGGGCTTGTAAA
TGGTAGACCATGTTTGATATTTCTCCTTTAGATCATTGGGTGCTTGATTTTGTTGTTAGTAAAT
AATATTTTGAGGCATCTTCTATGTTCATCTAGAAACATGAACAAATAGTGTTTGTTGTAAACTA
TGTGTGAACATATATACTTGGAATTTTCTTCACACAAATGAGGTATGTGTACATTTTATGTAAA
TAAAATAAT

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Protein Sequences


Protein RefSeqs	XP_008759839	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL93677	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000058783.5
	ENSRNOP00000110516.1

RefSeq Acc Id:

XP_008759839 ⟸ XM_008761617

- UniProtKB:

A6JSW9 (UniProtKB/TrEMBL), F1LWT9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLRPLPLLVVPGLLQLLFCDSEKVIRTSESVDWEDRTVPGTLVRNVVHSRITSPVHLFVKQPL
GSKPAYADNLENFGDWLANRTEIQEPLARTKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLIT
GKIVDHGNGTFSVYFRHNSTGLGNVSVSLVPPSKIVEFEVSTQSSLETKESKSFNCHIEYEKTD
RAKKTALCNFDPSKICYQEQTQSHVSWLCSKPFKVICIHIAFYSIDYKLVQKVCPDYNYHSETP
YLTSG

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Ensembl Acc Id:

ENSRNOP00000058783 ⟸ ENSRNOT00000062080

Ensembl Acc Id:

ENSRNOP00000110516 ⟸ ENSRNOT00000141026

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LWT9-F1-model_v2	AlphaFold	F1LWT9	1-259	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1598138	AgrOrtholog
BioCyc Gene	G2FUF-50534	BioCyc
Ensembl Genes	ENSRNOG00000040333	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000062080.5	UniProtKB/TrEMBL
	ENSRNOT00000141026.1	UniProtKB/TrEMBL
InterPro	Nxph	UniProtKB/TrEMBL
	NXPH/NXPE	UniProtKB/TrEMBL
KEGG Report	rno:679932	UniProtKB/TrEMBL
NCBI Gene	679932	ENTREZGENE
PANTHER	NEUREXOPHILIN-2	UniProtKB/TrEMBL
	PTHR17103	UniProtKB/TrEMBL
Pfam	Neurexophilin	UniProtKB/TrEMBL
PhenoGen	Nxph2	PhenoGen
PIRSF	Neurexophilin	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000040333	RatGTEx
UniProt	A0ABK0M5T7_RAT	UniProtKB/TrEMBL
	A6JSW9	ENTREZGENE, UniProtKB/TrEMBL
	F1LWT9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-05	Nxph2	neurexophilin 2	LOC679932	similar to neurexophilin 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC679932	similar to neurexophilin 2	LOC687026	similar to neurexophilin 2	Data merged from RGD:1590142	1643240	APPROVED
2006-11-20	LOC679932	similar to neurexophilin 2			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC687026	similar to neurexophilin 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD