C17h10orf67 (similar to human chromosome 10 open reading frame 67) - Rat Genome Database

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Pathways
Gene: C17h10orf67 (similar to human chromosome 10 open reading frame 67) Rattus norvegicus
Analyze
Symbol: C17h10orf67
Name: similar to human chromosome 10 open reading frame 67
RGD ID: 1598031
Description: Orthologous to human C10orf67 (chromosome 10 open reading frame 67); INTERACTS WITH aflatoxin B1 (ortholog); arsane (ortholog); arsenic atom (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC681241; LOC681241; uncharacterized protein C10orf67 homolog, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,970,801 - 87,082,723 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1786,980,186 - 87,082,700 (-)EnsemblGRCr8
mRatBN7.21782,062,461 - 82,174,401 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1782,071,838 - 82,174,353 (-)EnsemblmRatBN7.2
Rnor_6.01786,227,106 - 86,322,177 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1786,239,087 - 86,322,144 (-)Ensemblrn6Rnor6.0
Rnor_5.01787,915,286 - 88,032,655 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41793,515,546 - 93,620,296 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1781,351,127 - 81,446,290 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C17h10orf67
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,970,801 - 87,082,723 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1786,980,186 - 87,082,700 (-)EnsemblGRCr8
mRatBN7.21782,062,461 - 82,174,401 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1782,071,838 - 82,174,353 (-)EnsemblmRatBN7.2
Rnor_6.01786,227,106 - 86,322,177 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1786,239,087 - 86,322,144 (-)Ensemblrn6Rnor6.0
Rnor_5.01787,915,286 - 88,032,655 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41793,515,546 - 93,620,296 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1781,351,127 - 81,446,290 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
C10orf67
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381023,201,916 - 23,344,797 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1023,202,696 - 23,344,845 (-)Ensemblhg38GRCh38
GRCh371023,490,845 - 23,633,726 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361023,645,526 - 23,673,778 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341023,645,526 - 23,673,778NCBI
Celera1023,293,123 - 23,322,454 (-)NCBICelera
Cytogenetic Map10p12.2NCBI
HuRef1023,265,648 - 23,294,689 (-)NCBIHuRef
CHM1_11023,606,039 - 23,634,174 (-)NCBICHM1_1
T2T-CHM13v2.01023,220,910 - 23,364,923 (-)NCBIT2T-CHM13v2.0
4921504E06Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39219,467,648 - 19,558,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl219,467,648 - 19,558,725 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38219,462,837 - 19,553,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl219,462,837 - 19,553,914 (-)Ensemblmm10GRCm38
MGSCv37219,384,464 - 19,475,537 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36219,380,591 - 19,471,664 (-)NCBIMGSCv36mm8
Celera219,361,899 - 19,453,082 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map213.4NCBI
LOC102011029
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554295,674,076 - 5,798,289 (+)NCBIChiLan1.0ChiLan1.0
C8H10orf67
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2835,884,421 - 36,040,147 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11035,889,751 - 36,046,368 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01023,366,945 - 23,516,413 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11023,808,475 - 23,889,194 (-)NCBIPanPan1.1PanPan1.1panPan2
C2H10orf67
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.129,864,753 - 10,061,384 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl29,900,035 - 10,067,876 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha28,556,863 - 8,753,198 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.028,067,182 - 8,257,543 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl28,102,265 - 8,256,114 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.127,433,695 - 7,622,939 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.027,517,150 - 7,705,529 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.027,684,439 - 7,874,235 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH10orf67
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934422,990,835 - 23,123,127 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365204,837,373 - 4,950,732 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365204,837,373 - 4,968,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C10H10orf67
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1051,683,329 - 51,812,646 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11051,683,170 - 51,812,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21057,337,683 - 57,470,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C9H10orf67
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1922,975,457 - 23,085,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605128,739,338 - 28,874,524 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH10orf67
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247965,423,959 - 5,466,321 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C14H10orf67
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1144,504,192 - 4,641,480 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:139
Count of miRNA genes:107
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000034474
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat

Markers in Region
D17Rat177  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81786,995,153 - 86,995,367 (+)Marker Load Pipeline
mRatBN7.21782,086,813 - 82,087,027 (+)MAPPERmRatBN7.2
Rnor_6.01786,234,442 - 86,234,655NCBIRnor6.0
Rnor_5.01787,945,994 - 87,946,207UniSTSRnor5.0
RGSC_v3.41793,530,221 - 93,530,435RGDRGSC3.4
RGSC_v3.41793,530,222 - 93,530,435UniSTSRGSC3.4
Celera1781,359,177 - 81,359,390UniSTS
RGSC_v3.11793,541,054 - 93,541,268RGD
SHRSP x BN Map1747.5999UniSTS
SHRSP x BN Map1747.5999RGD
Cytogenetic Map17q12.3UniSTS
D17Got109  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21782,156,496 - 82,156,663 (+)MAPPERmRatBN7.2
Rnor_6.01786,304,573 - 86,304,739NCBIRnor6.0
Rnor_5.01788,014,963 - 88,015,129UniSTSRnor5.0
RGSC_v3.41793,601,999 - 93,602,166RGDRGSC3.4
RGSC_v3.41793,602,000 - 93,602,166UniSTSRGSC3.4
Celera1781,428,535 - 81,428,705UniSTS
RGSC_v3.11793,612,833 - 93,612,999RGD
RH 3.4 Map17835.8UniSTS
RH 3.4 Map17835.8RGD
RH 2.0 Map17721.6RGD
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 3 20 115 47 46 15 30 15 6 128 75 6 93 30 57 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000034474   ⟹   ENSRNOP00000029728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1786,980,186 - 87,082,700 (-)Ensembl
mRatBN7.2 Ensembl1782,071,838 - 82,174,353 (-)Ensembl
Rnor_6.0 Ensembl1786,239,087 - 86,322,144 (-)Ensembl
RefSeq Acc Id: NM_001419562   ⟹   NP_001406491
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,980,186 - 87,082,700 (-)NCBI
mRatBN7.21782,071,846 - 82,174,358 (-)NCBI
RefSeq Acc Id: XM_008771933   ⟹   XP_008770155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,983,591 - 87,082,723 (-)NCBI
mRatBN7.21782,078,657 - 82,174,401 (-)NCBI
Rnor_6.01786,227,106 - 86,322,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096205   ⟹   XP_038952133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,970,801 - 87,082,723 (-)NCBI
mRatBN7.21782,062,461 - 82,174,401 (-)NCBI
RefSeq Acc Id: XM_039096207   ⟹   XP_038952135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,974,503 - 87,082,723 (-)NCBI
mRatBN7.21782,073,422 - 82,174,401 (-)NCBI
RefSeq Acc Id: XM_039096208   ⟹   XP_038952136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,983,591 - 87,065,628 (-)NCBI
mRatBN7.21782,078,657 - 82,157,183 (-)NCBI
RefSeq Acc Id: XM_063276741   ⟹   XP_063132811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,998,941 - 87,082,723 (-)NCBI
RefSeq Acc Id: XM_063276742   ⟹   XP_063132812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,970,801 - 87,065,627 (-)NCBI
RefSeq Acc Id: XM_063276743   ⟹   XP_063132813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,974,503 - 87,065,627 (-)NCBI
RefSeq Acc Id: XM_063276744   ⟹   XP_063132814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,974,503 - 87,065,627 (-)NCBI
RefSeq Acc Id: XM_063276745   ⟹   XP_063132815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,999,338 - 87,065,628 (-)NCBI
RefSeq Acc Id: XR_005495400
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,974,503 - 87,082,723 (-)NCBI
mRatBN7.21782,073,422 - 82,174,401 (-)NCBI
RefSeq Acc Id: XR_010058939
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,974,503 - 87,082,723 (-)NCBI
RefSeq Acc Id: XP_008770155   ⟸   XM_008771933
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000029728   ⟸   ENSRNOT00000034474
RefSeq Acc Id: XP_038952133   ⟸   XM_039096205
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952135   ⟸   XM_039096207
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038952136   ⟸   XM_039096208
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001406491   ⟸   NM_001419562
- UniProtKB: D4ADD9 (UniProtKB/TrEMBL),   A6JMA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132812   ⟸   XM_063276742
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063132813   ⟸   XM_063276743
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132814   ⟸   XM_063276744
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063132811   ⟸   XM_063276741
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063132815   ⟸   XM_063276745
- Peptide Label: isoform X9
Protein Domains
DUF4709   DUF4724

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADD9-F1-model_v2 AlphaFold D4ADD9 1-494 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1598031 AgrOrtholog
BioCyc Gene G2FUF-8527 BioCyc
Ensembl Genes ENSRNOG00000021898 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034474 ENTREZGENE
  ENSRNOT00000034474.8 UniProtKB/TrEMBL
InterPro C10orf67-like UniProtKB/TrEMBL
  DUF4709 UniProtKB/TrEMBL
  DUF4724 UniProtKB/TrEMBL
NCBI Gene 681241 ENTREZGENE
PANTHER PTHR22382 UniProtKB/TrEMBL
  RIKEN CDNA 4921504E06 GENE UniProtKB/TrEMBL
Pfam DUF4709 UniProtKB/TrEMBL
  DUF4724 UniProtKB/TrEMBL
PhenoGen C17h10orf67 PhenoGen
RatGTEx ENSRNOG00000021898 RatGTEx
UniProt A6JMA5 ENTREZGENE, UniProtKB/TrEMBL
  D4ADD9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C17h10orf67  similar to human chromosome 10 open reading frame 67  LOC681241  hypothetical protein LOC681241  Symbol and Name Changed 1299863 APPROVED
2006-11-20 LOC681241  hypothetical protein LOC681241      Symbol and Name status set to provisional 70820 PROVISIONAL