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Gene: Zfp296 (zinc finger protein 296) Rattus norvegicus

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Symbol:

Zfp296

Name:

zinc finger protein 296

RGD ID:

1595818

Description:

Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of dendrite development; regulation of transcription by RNA polymerase II; and spermatogenesis. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF296 (zinc finger protein 296); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC365511; similar to zinc finger protein 296; Znf296

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF296 (zinc finger protein 296)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB
Mus musculus (house mouse):	Zfp296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Znf296 (zinc finger protein 296)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZNF296 (zinc finger protein 296)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp296 (zinc finger protein 296)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	znf296 (zinc finger protein 296)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	88,356,653 - 88,359,841 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	88,352,530 - 88,359,840 (+)	Ensembl				GRCr8
mRatBN7.2	1	79,228,649 - 79,231,866 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	79,228,401 - 79,231,866 (+)	Ensembl				mRatBN7.2
Dahl_SR_JrHsd	1	86,976,437 - 86,979,683 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	92,113,446 - 92,116,692 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	88,653,750 - 88,656,996 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	87,102,391 - 87,105,637 (+)	NCBI		F344_StmMcwi
Rnor_6.0	1	80,487,193 - 80,491,422 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	80,487,938 - 80,491,039 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	81,753,950 - 81,757,459 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	1	73,687,418 - 73,691,647 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

cadmium atom (ISO)

CGP 52608 (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

formaldehyde (ISO)

furan (EXP)

inulin (ISO)

Licochalcone B (ISO)

methimazole (EXP)

methylisothiazolinone (ISO)

niclosamide (ISO)

nitrates (ISO)

ozone (ISO)

paracetamol (EXP)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

PhIP (ISO)

potassium chromate (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

negative regulation of dendrite development (IBA)

regulation of transcription by RNA polymerase II (IBA)

spermatogenesis (IEA,ISO)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

DNA-binding transcription factor activity (IBA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific double-stranded DNA binding (IEA,ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11063263	PMID:24161396

Genomics

Comparative Map Data

Zfp296
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	88,356,653 - 88,359,841 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	88,352,530 - 88,359,840 (+)	Ensembl				GRCr8
mRatBN7.2	1	79,228,649 - 79,231,866 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	79,228,401 - 79,231,866 (+)	Ensembl				mRatBN7.2
Dahl_SR_JrHsd	1	86,976,437 - 86,979,683 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	92,113,446 - 92,116,692 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	88,653,750 - 88,656,996 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	87,102,391 - 87,105,637 (+)	NCBI		F344_StmMcwi
Rnor_6.0	1	80,487,193 - 80,491,422 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	80,487,938 - 80,491,039 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	81,753,950 - 81,757,459 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	1	73,687,418 - 73,691,647 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

ZNF296
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	45,071,500 - 45,076,478 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	45,071,500 - 45,076,478 (-)	Ensembl			hg38	GRCh38
GRCh37	19	45,574,758 - 45,579,736 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	50,266,598 - 50,271,528 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	50,266,598 - 50,271,528	NCBI
Celera	19	42,379,045 - 42,383,975 (-)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	42,004,983 - 42,009,811 (-)	NCBI		HuRef
CHM1_1	19	45,578,088 - 45,583,042 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	47,896,615 - 47,901,608 (-)	NCBI		T2T-CHM13v2.0

Zfp296
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	19,311,212 - 19,314,581 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	19,311,212 - 19,314,581 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	19,577,287 - 19,580,656 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	19,577,287 - 19,580,656 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	20,162,636 - 20,166,005 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	18,736,338 - 18,739,177 (+)	NCBI		MGSCv36	mm8
Celera	7	16,983,052 - 16,986,421 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	9.93	NCBI

Znf296
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955555	2,109,682 - 2,113,922 (-)	Ensembl
ChiLan1.0	NW_004955555	2,109,980 - 2,114,002 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZNF296
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	51,232,109 - 51,238,657 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	53,103,509 - 53,109,428 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	42,019,936 - 42,025,304 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	50,623,782 - 50,630,027 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	50,623,782 - 50,630,027 (-)	Ensembl			panPan2	panpan1.1

ZNF296
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	110,405,643 - 110,411,848 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	110,408,058 - 110,411,744 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	109,887,079 - 109,893,570 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	110,935,757 - 110,942,247 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	110,938,446 - 110,942,245 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	110,611,015 - 110,617,504 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	110,246,181 - 110,252,672 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	111,114,986 - 111,121,478 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znf296
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	17,276,013 - 17,279,796 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936706	1,623,354 - 1,627,140 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936706	1,623,386 - 1,627,068 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF296
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	51,504,388 - 51,508,324 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	51,504,384 - 51,508,284 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ZNF296
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	38,531,046 - 38,536,746 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	38,531,146 - 38,536,235 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	18,121,705 - 18,128,622 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf296
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624907	1,852,995 - 1,857,150 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624907	1,853,118 - 1,857,496 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Znf296
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	171,043,063 - 171,046,754 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Zfp296
13 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	154
Count of miRNA genes:	130
Interacting mature miRNAs:	143
Transcripts:	ENSRNOT00000074579
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	64	159	89	88	57	86	57	6	341	183	11	137	78	92	31	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001075949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_345065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000074579 ⟹ ENSRNOP00000064037

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	88,352,530 - 88,359,840 (+)	Ensembl
mRatBN7.2 Ensembl	1	79,228,401 - 79,231,866 (+)	Ensembl
Rnor_6.0 Ensembl	1	80,487,938 - 80,491,039 (+)	Ensembl

RefSeq Acc Id:

NM_001432364 ⟹ NP_001419293

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Dahl_SR_JrHsd	1	86,976,437 - 86,979,683 (+)	NCBI
Lyon_Normotensive	1	92,113,446 - 92,116,692 (+)	NCBI
Lyon_Hypertensive	1	88,653,750 - 88,656,996 (+)	NCBI
F344_StmMcwi	1	87,102,391 - 87,105,637 (+)	NCBI

RefSeq Acc Id:

XM_345065 ⟹ XP_345066

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	88,356,653 - 88,359,841 (+)	NCBI
mRatBN7.2	1	79,228,649 - 79,231,866 (+)	NCBI
Rnor_6.0	1	80,487,193 - 80,491,422 (+)	NCBI
Rnor_5.0	1	81,753,950 - 81,757,459 (+)	NCBI

Sequence:

show sequence

TGGGCTTGAATTCAGAGAATCCACCTTTCTCTGCCTCCGGAGCATTAGGATTAAAGGCATGCAC
TTTTACAGTCATTTCTATGTGGTGACCACTCCCTCTCACTGCCACCCTCCATCCCCACATTATG
GAATGAAGTCTGGGATGTAGCCCACTGGGTGGAACACTTGACTAGAAGAGTGTCAGAGGTTCTG
AGTTCAATGCCCAGCACCACACAATATAGGTGTAGTGAGGCACCCCTGTAAAACCACCGCTGGA
GAGGGGGAAGAAAATCAAACGAACGAAGCCATCCTCAAACTAGCCGTTACATGGCTAGTTTGAG
CTTAAAAGGCAAAAAAGAAAAAAAGAGGGGGGGTGTTTAAAGCGAAATTTTCTTAGTATACTTC
CCCACTAGTGAGAGATGTCCACCACTTCTCGCTTGGGGGATGAGGGGCTGCATCCCGAGCCTCA
GGTATCACCAGCGCCTAGGGGTGGGAACGAGGGGCACTGGGAATAGCTTTTTTCACTCTCCTGG
GTGAAATCGAGCCCAAGGGAGGAGGGCACAATTTGCGCACTGGTCCCCGGGGCAGCGGGCTGGG
CGGGGAAGGTCGAGTTTGACCGCCGCGACTGGCCCCGAAAAGACCCCGCCCCAGTGGGCGGAGA
CAAGGCAGGACCAGCACGTGTAAAAGGTTCGGCGCGGGTCGCCTAGAGCTACTCACTCACCTGA
GCGCCTGGCCGCTACGCGAATTACCTCTGCGTTCTTGCCCCATGTCCCGCCGCAAGGCCGGCCG
CGTGCCTCGCCGCGTAGACCCGGAGCCCAACGACGACATGGAGATGCCTGATCTCATCATTGAT
GTGAAACCGGACCGCGACCTGGGGTCCTTGGCACAAGGGCCCTGGTCCGCGAGGGACGTGCCCA
TGCCGGGGCTCTTCGATGTGGAGCGTCGCCTCCAAACCGCCTCGCGCCCACTTGGCGCGCCCAG
CACGTGTGCCCCGTGGATGCCTCTGAGTTCTATGTCTTCCGACCGCCAGCCCTGGACCGACAAG
CACCCAGATCTGTTGACCTGCGGCCGCTGCGGGAAGATCTTCCCATTAGGGTCCATCACCGCTT
TTATGGATCACAAAAAGCAAGGCTGTCAGCTCCGTCAAATCTCCGACCCCATCTCAGAATCCAA
AGAGCTGAAGGCTCTGAGCTGCCTCCAATGTGGCAGACAGTACACCAGTGCTTGGAAGTTGCTG
TGCCACGCCCAGTGGGACCATGGGCTATGCATCTACCAGACACAACAATTGGAGACCCCAGAGG
CTCCGTTGCTGGGCCTGGCTGAGGTGGCTGCAGCCATGTCAGCAGTGGCAGTGGTGGGGCCAGT
TGAGGACAAGCCCCCTTCAGTGAGTAGCGCTGCCCGGCGGAGCCCTACCTGCTTCGTGTGTAAG
AAGACCCTCAGCTCTTTCAGCAACCTCAAGGTCCACATGCGTTCCCACACTGGTGAGCGACCCT
ACTCCTGTGACCAGTGTTCCTATTCCTGCGCTCAGAGCAGCAAGCTGAACAGACACAAGAAGAC
CCATCGGCAGCCAACGCCTGGGAGCCCCTCCACTTCTGCCAGTAGCCGCGAAGTCTCCCCAGCA
GCCCCTCCTGAACCAGCTGCCTATGCAGCTGCTCCAGCCAGCACTCCCCCATGCCAGAATGTGG
AGAAGGCTGGAGCTGCCGCCACAGCCGGAATTCAGGAACCTGGGGCCCCTGGCAGTGGGGCTCA
AGAGAGTCCAGGTTTTGGTGGCTGTGGAGCCACTGCCAAAGTAGAGAGGACGGACTCTGTAAAG
ATGGAGAAGACAACACCCAGGAAGAGTCACCGGGCTGGGGGCAAGTGTGAGTTCTGCGGGAAGT
CCTTCACCAACAGCAGCAACCTCACGGTGCATCGGCGATCGCACACTGGCGAGCGGCCCTATAC
CTGTGACCAGTGTTCCTATGCCTGTGCCCAGAGCAGCAAGCTCAACCGCCACCGCCGCACACAC
GGGCTGGGAACTGGCAAGACTGTGTACAAGTGCCCGCACTGCCTCGTACCCTTTGTCCTGCAGG
CCACGCTGGACAAGCACCTGAGGCAGAAGCACCCGGAGATGGCCTGAGATGTTCTGTACAGACA
GGTGTTCCTCAGCAAGAGGACACGGCCAGCACTTAGCCATTCTTTTGTGTAAATAAACCATCTC
CTATTTATTCGTGTGCCTGGACTTGGGCTTTCTTGGGGTGTCTGAGGTGGGATGCTCCCTCCAT
AGTGTGGACAGCTGGACAGACCGGTTTGGAGTGGGGGGTAAGTGCCCTGGGCACTGGAGGACTG
GCACAGAAAGCTGTGCTCCCGGTTCTTGGTGTGGGTGAGGCCAGGGGCAGGGAGAGGCCTGGAC
CTGTCACCAGAGGCTTCTGGGCCCAGTCCAGTCCTATCCCGTCATCCACTGGCCCTGTCCACAC
ATGCCATAGTCTGGGCCTTTGACTGGATTGGCCCCTTCCTCCTGCCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001419293	(Get FASTA)	NCBI Sequence Viewer
	XP_345066	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM08183	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064037
	ENSRNOP00000064037.4

RefSeq Acc Id:

XP_345066 ⟸ XM_345065

- Sequence:

show sequence

MSRRKAGRVPRRVDPEPNDDMEMPDLIIDVKPDRDLGSLAQGPWSARDVPMPGLFDVERRLQTA
SRPLGAPSTCAPWMPLSSMSSDRQPWTDKHPDLLTCGRCGKIFPLGSITAFMDHKKQGCQLRQI
SDPISESKELKALSCLQCGRQYTSAWKLLCHAQWDHGLCIYQTQQLETPEAPLLGLAEVAAAMS
AVAVVGPVEDKPPSVSSAARRSPTCFVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYSCAQSS
KLNRHKKTHRQPTPGSPSTSASSREVSPAAPPEPAAYAAAPASTPPCQNVEKAGAAATAGIQEP
GAPGSGAQESPGFGGCGATAKVERTDSVKMEKTTPRKSHRAGGKCEFCGKSFTNSSNLTVHRRS
HTGERPYTCDQCSYACAQSSKLNRHRRTHGLGTGKTVYKCPHCLVPFVLQATLDKHLRQKHPEM
A

hide sequence

Ensembl Acc Id:

ENSRNOP00000064037 ⟸ ENSRNOT00000074579

RefSeq Acc Id:

NP_001419293 ⟸ NM_001432364

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0R3W4-F1-model_v2	AlphaFold	M0R3W4	1-450	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689785

Promoter ID:

EPDNEW_R298

Type:

single initiation site

Name:

Zfp296_1

Description:

zinc finger protein 296

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	80,487,883 - 80,487,943	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1595818	AgrOrtholog
BioCyc Gene	G2FUF-60495	BioCyc
Ensembl Genes	ENSRNOG00000049605	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000074579	ENTREZGENE
	ENSRNOT00000074579.4	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	BCL-11A_Znf_CCHC	UniProtKB/TrEMBL
	Dev/Hematopoietic_TF	UniProtKB/TrEMBL
	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
KEGG Report	rno:365511	UniProtKB/TrEMBL
NCBI Gene	365511	ENTREZGENE
PANTHER	B-CELL LYMPHOMA/LEUKEMIA 11	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 296	UniProtKB/TrEMBL
Pfam	CCHC_BCL-11A	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PhenoGen	Zfp296	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000049605	RatGTEx
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A6J8Q1	ENTREZGENE, UniProtKB/TrEMBL
	M0R3W4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-07-19	Zfp296	zinc finger protein 296	Znf296	zinc finger protein 296	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Znf296	zinc finger protein 296	Zfp296	zinc finger protein 296	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Zfp296	zinc finger protein 296	LOC365511	similar to zinc finger protein 296	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC365511	similar to zinc finger protein 296			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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