Spata45 (spermatogenesis associated 45) - Rat Genome Database

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Pathways
Gene: Spata45 (spermatogenesis associated 45) Rattus norvegicus
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Symbol: Spata45
Name: spermatogenesis associated 45
RGD ID: 1593182
Description: Orthologous to human SPATA45 (spermatogenesis associated 45); INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog); 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical LOC498316; hypothetical protein LOC498316; LOC498316; SPATA45l1; spermatogenesis associated 45-like 1; spermatogenesis-associated protein 45; uncharacterized protein LOC498316
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Spata45-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,155,421 - 105,162,321 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13105,158,690 - 105,162,321 (+)EnsemblGRCr8
mRatBN7.213102,624,298 - 102,631,191 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13102,625,273 - 102,631,191 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13105,145,348 - 105,151,266 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013106,529,312 - 106,535,230 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013103,744,297 - 103,750,215 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013109,645,480 - 109,652,233 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13109,646,455 - 109,652,229 (+)Ensemblrn6Rnor6.0
Rnor_5.013114,240,426 - 114,247,156 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera13102,091,408 - 102,097,326 (+)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Spata45
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,155,421 - 105,162,321 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13105,158,690 - 105,162,321 (+)EnsemblGRCr8
mRatBN7.213102,624,298 - 102,631,191 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13102,625,273 - 102,631,191 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13105,145,348 - 105,151,266 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013106,529,312 - 106,535,230 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013103,744,297 - 103,750,215 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013109,645,480 - 109,652,233 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13109,646,455 - 109,652,229 (+)Ensemblrn6Rnor6.0
Rnor_5.013114,240,426 - 114,247,156 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera13102,091,408 - 102,097,326 (+)NCBICelera
Cytogenetic Map13q27NCBI
SPATA45
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,830,141 - 212,847,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1212,830,141 - 212,847,649 (-)Ensemblhg38GRCh38
GRCh371213,003,483 - 213,020,991 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361211,070,106 - 211,087,614 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1186,229,475 - 186,246,986 (-)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1183,680,222 - 183,698,104 (-)NCBIHuRef
T2T-CHM13v2.01212,075,115 - 212,092,629 (-)NCBIT2T-CHM13v2.0
Spata45
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391190,768,106 - 190,775,139 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1190,768,836 - 190,775,139 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381191,035,909 - 191,042,942 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,036,639 - 191,042,942 (+)Ensemblmm10GRCm38
MGSCv371192,860,701 - 192,866,820 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361192,737,437 - 192,743,557 (+)NCBIMGSCv36mm8
Celera1197,961,735 - 197,967,537 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.28NCBI

Variants

.
Variants in Spata45
29 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:35
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000073985
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
2 8 1 82 18 14 4 4 5 45 11 2 72 22 62 10 3 3

Sequence


Ensembl Acc Id: ENSRNOT00000073985   ⟹   ENSRNOP00000065792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13105,158,690 - 105,162,321 (+)Ensembl
mRatBN7.2 Ensembl13102,625,273 - 102,631,191 (+)Ensembl
Rnor_6.0 Ensembl13109,646,455 - 109,652,229 (+)Ensembl
RefSeq Acc Id: NM_001109085   ⟹   NP_001102555
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,156,403 - 105,162,321 (+)NCBI
mRatBN7.213102,625,273 - 102,631,191 (+)NCBI
Rnor_6.013109,646,455 - 109,652,229 (+)NCBI
Rnor_5.013114,240,426 - 114,247,156 (+)NCBI
Celera13102,091,408 - 102,097,326 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250489   ⟹   XP_006250551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,155,421 - 105,162,318 (+)NCBI
mRatBN7.213102,624,298 - 102,631,191 (+)NCBI
Rnor_6.013109,645,480 - 109,652,233 (+)NCBI
Rnor_5.013114,240,426 - 114,247,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090999   ⟹   XP_038946927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,157,068 - 105,162,318 (+)NCBI
mRatBN7.213102,626,151 - 102,631,191 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102555 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250551 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946927 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94988 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065792
  ENSRNOP00000065792.1
RefSeq Acc Id: NP_001102555   ⟸   NM_001109085
- UniProtKB: M0R8J6 (UniProtKB/TrEMBL),   A6JGY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250551   ⟸   XM_006250489
- Peptide Label: isoform X1
- UniProtKB: M0R8J6 (UniProtKB/TrEMBL),   A6JGY2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065792   ⟸   ENSRNOT00000073985
RefSeq Acc Id: XP_038946927   ⟸   XM_039090999
- Peptide Label: isoform X1
- UniProtKB: M0R8J6 (UniProtKB/TrEMBL),   A6JGY2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R8J6-F1-model_v2 AlphaFold M0R8J6 1-97 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699111
Promoter ID:EPDNEW_R9636
Type:initiation region
Name:LOC498316_1
Description:hypothetical LOC498316
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013109,646,457 - 109,646,517EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593182 AgrOrtholog
BioCyc Gene G2FUF-16869 BioCyc
Ensembl Genes ENSRNOG00000048659 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073985 ENTREZGENE
  ENSRNOT00000073985.3 UniProtKB/TrEMBL
InterPro SPATA45 UniProtKB/TrEMBL
KEGG Report rno:498316 UniProtKB/TrEMBL
NCBI Gene 498316 ENTREZGENE
PANTHER PTHR35822 UniProtKB/TrEMBL
  SPERMATOGENESIS-ASSOCIATED PROTEIN 45 UniProtKB/TrEMBL
PhenoGen Spata45 PhenoGen
RatGTEx ENSRNOG00000048659 RatGTEx
UniProt A6JGY2 ENTREZGENE, UniProtKB/TrEMBL
  M0R8J6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-02-03 Spata45    SPATA45  spermatogenesis associated 45  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-03-10 SPATA45  spermatogenesis associated 45  SPATA45l1  spermatogenesis associated 45-like 1  Name and Symbol changed 629549 APPROVED
2021-10-29 SPATA45l1  spermatogenesis associated 45-like 1  LOC498316  hypothetical LOC498316  Name and Symbol changed 629549 APPROVED
2006-11-20 LOC498316  hypothetical LOC498316      Symbol and Name status set to provisional 70820 PROVISIONAL