Sun3 (Sad1 and UNC84 domain containing 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sun3 (Sad1 and UNC84 domain containing 3) Rattus norvegicus
Analyze
Symbol: Sun3
Name: Sad1 and UNC84 domain containing 3
RGD ID: 1591975
Description: Predicted to enable protein-membrane adaptor activity. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in nuclear envelope. Orthologous to human SUN3 (Sad1 and UNC84 domain containing 3); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498412; Sad1 and UNC84 domain containing 1; similar to Sad1 and UNC84 domain containing 1; SUN domain-containing protein 3; Sunc1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81487,923,891 - 87,962,699 (-)NCBIGRCr8
mRatBN7.21483,710,136 - 83,748,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,710,140 - 83,735,830 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01489,215,386 - 89,253,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1489,215,703 - 89,238,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01489,012,900 - 89,050,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,549,426 - 89,573,888 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1482,746,240 - 82,785,252 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20711465  


Genomics

Comparative Map Data
Sun3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81487,923,891 - 87,962,699 (-)NCBIGRCr8
mRatBN7.21483,710,136 - 83,748,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,710,140 - 83,735,830 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01489,215,386 - 89,253,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1489,215,703 - 89,238,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01489,012,900 - 89,050,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,549,426 - 89,573,888 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1482,746,240 - 82,785,252 (-)NCBICelera
Cytogenetic Map14q21NCBI
SUN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38747,987,148 - 48,035,902 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl747,987,148 - 48,029,119 (-)EnsemblGRCh38hg38GRCh38
GRCh37748,026,745 - 48,068,704 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36747,993,270 - 48,035,241 (-)NCBINCBI36Build 36hg18NCBI36
Build 34747,799,993 - 47,841,944NCBI
Celera748,126,024 - 48,167,993 (-)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef747,912,236 - 47,954,201 (-)NCBIHuRef
CHM1_1748,030,470 - 48,072,418 (-)NCBICHM1_1
T2T-CHM13v2.0748,149,392 - 48,198,144 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2748,066,697 - 48,108,669 (-)NCBI
Sun3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39118,962,704 - 8,998,991 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl118,966,054 - 8,998,991 (-)EnsemblGRCm39 Ensembl
GRCm38119,016,043 - 9,048,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,016,054 - 9,048,991 (-)EnsemblGRCm38mm10GRCm38
MGSCv37118,916,057 - 8,948,994 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36118,916,057 - 8,948,994 (-)NCBIMGSCv36mm8
Celera119,448,424 - 9,486,332 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map115.77NCBI
Sun3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554565,423,920 - 5,445,741 (+)NCBIChiLan1.0ChiLan1.0
SUN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2652,863,884 - 52,964,433 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17101,188,617 - 101,287,849 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0748,629,697 - 48,728,738 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1748,738,436 - 48,779,798 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl748,738,493 - 48,779,798 (-)Ensemblpanpan1.1panPan2
SUN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11837,469 - 73,849 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1836,691 - 73,805 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha184,358 - 40,701 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01870,108 - 106,446 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1883,513 - 106,407 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,001 - 81,339 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01847,762 - 84,126 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.018182,978 - 219,324 (-)NCBIUU_Cfam_GSD_1.0
Sun3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118103,208,901 - 103,247,783 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647822,420,820 - 22,452,780 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647822,420,673 - 22,452,780 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,485,037 - 48,519,230 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,484,700 - 48,519,311 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SUN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12110,769,668 - 10,813,071 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2110,769,884 - 10,812,890 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606211,416,110 - 11,463,121 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sun3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247405,557,581 - 5,585,549 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247405,555,412 - 5,590,876 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sun3
195 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:55
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000006818
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 3 41 54 56 56 35 17 35 6 160 73 40 41 46 21

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001432834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005493415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000006818   ⟹   ENSRNOP00000006818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1483,710,140 - 83,735,830 (-)Ensembl
Rnor_6.0 Ensembl1489,215,703 - 89,238,094 (-)Ensembl
RefSeq Acc Id: XM_006251471   ⟹   XP_006251533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,923,891 - 87,962,699 (-)NCBI
mRatBN7.21483,710,136 - 83,748,982 (-)NCBI
Rnor_6.01489,215,386 - 89,253,585 (-)NCBI
Rnor_5.01489,012,900 - 89,050,968 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770406   ⟹   XP_008768628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,923,891 - 87,949,618 (-)NCBI
mRatBN7.21483,710,136 - 83,734,680 (-)NCBI
Rnor_6.01489,215,386 - 89,243,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599512   ⟹   XP_017455001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,923,891 - 87,947,682 (-)NCBI
mRatBN7.21483,710,136 - 83,733,926 (-)NCBI
Rnor_6.01489,215,386 - 89,239,341 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599513   ⟹   XP_017455002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,923,891 - 87,962,519 (-)NCBI
mRatBN7.21483,710,136 - 83,748,766 (-)NCBI
Rnor_6.01489,215,386 - 89,253,369 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092856   ⟹   XP_038948784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,923,891 - 87,949,618 (-)NCBI
mRatBN7.21483,710,136 - 83,735,866 (-)NCBI
RefSeq Acc Id: XM_039092857   ⟹   XP_038948785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,923,891 - 87,949,618 (-)NCBI
mRatBN7.21483,710,136 - 83,735,882 (-)NCBI
RefSeq Acc Id: XM_063273788   ⟹   XP_063129858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,928,968 - 87,962,699 (-)NCBI
RefSeq Acc Id: XM_063273789   ⟹   XP_063129859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,928,968 - 87,949,618 (-)NCBI
RefSeq Acc Id: XR_005493415
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,925,706 - 87,962,699 (-)NCBI
mRatBN7.21483,710,136 - 83,748,982 (-)NCBI
RefSeq Acc Id: XP_006251533   ⟸   XM_006251471
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008768628   ⟸   XM_008770406
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017455002   ⟸   XM_017599513
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017455001   ⟸   XM_017599512
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000006818   ⟸   ENSRNOT00000006818
RefSeq Acc Id: XP_038948785   ⟸   XM_039092857
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038948784   ⟸   XM_039092856
- Peptide Label: isoform X5
- UniProtKB: A6KJ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129858   ⟸   XM_063273788
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063129859   ⟸   XM_063273789
- Peptide Label: isoform X7
Protein Domains
SUN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LY77-F1-model_v2 AlphaFold F1LY77 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591975 AgrOrtholog
BioCyc Gene G2FUF-15023 BioCyc
Ensembl Genes ENSRNOG00000005105 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006818.6 UniProtKB/TrEMBL
Gene3D-CATH Galactose-binding domain-like UniProtKB/TrEMBL
InterPro Sad1_UNC_C UniProtKB/TrEMBL
  SUN1-5 UniProtKB/TrEMBL
NCBI Gene 498412 ENTREZGENE
PANTHER PTHR12911 UniProtKB/TrEMBL
  PTHR12911:SF24 UniProtKB/TrEMBL
Pfam Sad1_UNC UniProtKB/TrEMBL
PhenoGen Sun3 PhenoGen
PROSITE SUN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005105 RatGTEx
UniProt A6KJ85 ENTREZGENE, UniProtKB/TrEMBL
  F1LY77 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Sun3  Sad1 and UNC84 domain containing 3  Sunc1  Sad1 and UNC84 domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Sunc1  Sad1 and UNC84 domain containing 1  LOC498412  similar to Sad1 and UNC84 domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC498412  similar to Sad1 and UNC84 domain containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL