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Gene: Xpnpep3 (X-prolyl aminopeptidase 3) Rattus norvegicus

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Symbol:

Xpnpep3

Name:

X-prolyl aminopeptidase 3

RGD ID:

1589063

Description:

Predicted to enable manganese ion binding activity; metalloaminopeptidase activity; and protein homodimerization activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within glomerular filtration and protein processing. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nephronophthisis-like nephropathy 1. Orthologous to human XPNPEP3 (X-prolyl aminopeptidase 3); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

aminopeptidase P3; APP3; LOC685823; MGC188876; probable Xaa-Pro aminopeptidase 3; similar to CG9581-PA; X-Pro aminopeptidase 3; X-prolyl aminopeptidase (aminopeptidase P) 3, putative; X-prolyl aminopeptidase 3, mitochondrial; xaa-Pro aminopeptidase 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	XPNPEP3 (X-prolyl aminopeptidase 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Xpnpep3 (X-prolyl aminopeptidase 3, mitochondrial)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Xpnpep3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	XPNPEP3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	XPNPEP3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Xpnpep3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	XPNPEP3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	XPNPEP3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Xpnpep3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Xpnpep3 (X-prolyl aminopeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Xpnpep3 (X-prolyl aminopeptidase 3, mitochondrial)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	XPNPEP3 (X-prolyl aminopeptidase 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	xpnpep3 (X-prolyl aminopeptidase 3, mitochondrial)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ICP55	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ICP55	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9581	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	R119.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	xpnpep3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	xpnpep3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG32454	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	114,806,398 - 114,858,934 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	114,806,357 - 114,855,125 (+)	Ensembl				GRCr8
mRatBN7.2	7	112,926,154 - 112,978,793 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	112,926,248 - 112,974,878 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	114,688,588 - 114,737,270 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	116,912,089 - 116,960,769 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	116,881,498 - 116,930,179 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	122,636,252 - 122,686,983 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	122,636,171 - 122,688,819 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	122,612,798 - 122,661,434 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	119,729,428 - 119,779,023 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	109,245,696 - 109,321,789 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

kidney disease (ISO)

nephronophthisis-like nephropathy 1 (ISO)

Rubinstein-Taybi syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP,ISO)

bortezomib (ISO)

cadmium dichloride (EXP,ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

Cuprizon (EXP)

cypermethrin (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

glycidol (EXP)

hydroquinone (ISO)

lead(0) (ISO)

mercury dibromide (ISO)

methidathion (ISO)

methylmercury chloride (ISO)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

glomerular filtration (ISO)

protein processing (ISO)

proteolysis (IBA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (ISO)

mitochondrion (IBA,IEA,ISO)

Molecular Function

aminopeptidase activity (IBA,IEA,ISO)

hydrolase activity (IEA)

manganese ion binding (IEA,ISO)

metal ion binding (IEA)

metalloaminopeptidase activity (IEA,ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

presequence pathway of mitochondrial protein import (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Processing of mitochondrial presequences.	Mossmann D, etal., Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):1098-106. doi: 10.1016/j.bbagrm.2011.11.007. Epub 2011 Dec 7.
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:14651853	PMID:18614015	PMID:20179356	PMID:23376485	PMID:25609706	PMID:28476889

Genomics

Comparative Map Data

Xpnpep3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	114,806,398 - 114,858,934 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	114,806,357 - 114,855,125 (+)	Ensembl				GRCr8
mRatBN7.2	7	112,926,154 - 112,978,793 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	112,926,248 - 112,974,878 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	114,688,588 - 114,737,270 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	116,912,089 - 116,960,769 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	116,881,498 - 116,930,179 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	122,636,252 - 122,686,983 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	122,636,171 - 122,688,819 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	122,612,798 - 122,661,434 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	119,729,428 - 119,779,023 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	109,245,696 - 109,321,789 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

XPNPEP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	40,857,148 - 40,932,815 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	40,857,077 - 40,932,815 (+)	Ensembl			hg38	GRCh38
GRCh37	22	41,253,152 - 41,328,819 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	39,583,040 - 39,653,829 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	22	25,056,765 - 25,127,557 (+)	NCBI		Celera
Cytogenetic Map	22	q13.2	NCBI
HuRef	22	24,215,119 - 24,290,638 (+)	NCBI		HuRef
CHM1_1	22	41,211,837 - 41,287,590 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	41,329,340 - 41,405,008 (+)	NCBI		T2T-CHM13v2.0

Xpnpep3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	81,284,282 - 81,341,683 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	81,284,339 - 81,341,683 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	81,400,105 - 81,457,482 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	81,400,138 - 81,457,482 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	81,230,618 - 81,285,318 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	81,227,443 - 81,282,143 (+)	NCBI		MGSCv36	mm8
Celera	15	83,518,225 - 83,572,893 (+)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	38.08	NCBI

Xpnpep3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	26,507,860 - 26,566,826 (+)	Ensembl
ChiLan1.0	NW_004955413	26,507,860 - 26,564,105 (+)	NCBI	ChiLan1.0	ChiLan1.0

XPNPEP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	50,687,824 - 50,762,868 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	53,387,709 - 53,462,763 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	21,752,015 - 21,827,146 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	39,848,045 - 39,915,398 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	39,848,077 - 39,915,398 (+)	Ensembl			panPan2	panpan1.1

XPNPEP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	24,304,342 - 24,379,562 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	24,307,091 - 24,379,448 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	24,238,414 - 24,314,015 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	25,051,673 - 25,127,569 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	25,052,064 - 25,127,204 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	24,767,255 - 24,842,815 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	25,087,877 - 25,163,708 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	25,262,479 - 25,338,089 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Xpnpep3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	7,910,924 - 7,966,668 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	919,689 - 976,910 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	919,963 - 976,926 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

XPNPEP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	7,530,999 - 7,582,961 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	7,530,993 - 7,582,981 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

XPNPEP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	23,413,111 - 23,473,293 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	23,413,215 - 23,473,170 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	102,090,595 - 102,161,675 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Xpnpep3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	7,574,920 - 7,634,838 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624752	7,573,399 - 7,634,875 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Xpnpep3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	251,152,601 - 251,200,989 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Xpnpep3
230 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	396
Count of miRNA genes:	221
Interacting mature miRNAs:	256
Transcripts:	ENSRNOT00000068666
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

D7Rat68

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	114,862,235 - 114,862,447 (+)	Marker Load Pipeline
mRatBN7.2	7	112,982,090 - 112,982,302 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,692,089 - 122,692,300	NCBI	Rnor6.0
Rnor_5.0	7	122,668,635 - 122,668,846	UniSTS	Rnor5.0
RGSC_v3.4	7	119,785,294 - 119,785,506	RGD	RGSC3.4
RGSC_v3.4	7	119,785,295 - 119,785,506	UniSTS	RGSC3.4
Celera	7	109,301,425 - 109,301,634	UniSTS
RGSC_v3.1	7	119,819,525 - 119,819,736	RGD
RH 3.4 Map	7	880.5	RGD
RH 3.4 Map	7	880.5	UniSTS
RH 2.0 Map	7	663.9	RGD
SHRSP x BN Map	7	65.7799	RGD
FHH x ACI Map	7	53.38	RGD
Cytogenetic Map	7	q34	UniSTS

RH137490

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	112,996,536 - 112,996,742 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,706,572 - 122,706,777	NCBI	Rnor6.0
Rnor_5.0	7	122,682,583 - 122,682,788	UniSTS	Rnor5.0
RGSC_v3.4	7	119,799,479 - 119,799,684	UniSTS	RGSC3.4
Celera	7	109,315,848 - 109,316,053	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH131226

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	113,000,747 - 113,000,930 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,710,604 - 122,710,786	NCBI	Rnor6.0
Rnor_5.0	7	122,686,773 - 122,686,955	UniSTS	Rnor5.0
RGSC_v3.4	7	119,804,801 - 119,804,983	UniSTS	RGSC3.4
Celera	7	109,319,932 - 109,320,114	UniSTS
RH 3.4 Map	7	878.9	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH142947

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	112,992,368 - 112,992,491 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,702,383 - 122,702,505	NCBI	Rnor6.0
Rnor_5.0	7	122,678,929 - 122,679,051	UniSTS	Rnor5.0
Celera	7	109,311,700 - 109,311,822	UniSTS
RH 3.4 Map	7	880.6	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH137754

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	112,991,861 - 112,992,039 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,701,876 - 122,702,053	NCBI	Rnor6.0
Rnor_5.0	7	122,678,422 - 122,678,599	UniSTS	Rnor5.0
Celera	7	109,311,193 - 109,311,370	UniSTS
Cytogenetic Map	7	q34	UniSTS

AW535011

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	114,854,798 - 114,854,948 (+)	Marker Load Pipeline
mRatBN7.2	7	112,974,653 - 112,974,803 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,684,653 - 122,684,802	NCBI	Rnor6.0
Rnor_5.0	7	122,661,199 - 122,661,348	UniSTS	Rnor5.0
RGSC_v3.4	7	119,777,858 - 119,778,007	UniSTS	RGSC3.4
RH 3.4 Map	7	878.3	UniSTS
Cytogenetic Map	7	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001130582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000068666 ⟹ ENSRNOP00000061709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,806,357 - 114,852,119 (+)	Ensembl
mRatBN7.2 Ensembl	7	112,926,248 - 112,971,974 (+)	Ensembl
Rnor_6.0 Ensembl	7	122,636,171 - 122,688,819 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111293 ⟹ ENSRNOP00000082871

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,806,357 - 114,855,125 (+)	Ensembl
mRatBN7.2 Ensembl	7	112,926,248 - 112,974,878 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115368 ⟹ ENSRNOP00000094221

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,806,357 - 114,855,025 (+)	Ensembl
mRatBN7.2 Ensembl	7	112,926,248 - 112,974,878 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154702 ⟹ ENSRNOP00000105591

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,819,723 - 114,855,025 (+)	Ensembl

RefSeq Acc Id:

NM_001130582 ⟹ NP_001124054

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	114,806,398 - 114,855,034 (+)	NCBI
mRatBN7.2	7	112,926,248 - 112,974,889 (+)	NCBI
Rnor_6.0	7	122,636,252 - 122,684,888 (+)	NCBI
Rnor_5.0	7	122,612,798 - 122,661,434 (+)	NCBI
RGSC_v3.4	7	119,729,428 - 119,779,023 (+)	RGD
Celera	7	109,245,696 - 109,321,789 (+)	NCBI

Sequence:

show sequence

GCTTTCCCCGCAATTTGTACTTTCTCTTCCTGACCAGTGGGTGCTGGCCATGCTGTCTCTGCTC
TCAACCCCCAGGCTGGTTCCCGTTATAGCAAGGCTCCGCGGCCTCTCAGGATGCATGTCATGTT
TACAGCGAAGGTACTCCCTCCAGCCGGTGCCAGTAAAGGAAATTCCAAACCGGTACTTAGGCCA
GCCCAGCCCGGTTACACATCCACACCTCCTCAGACCAGGGGAGGTGACACCAGGGCTATCTCAG
GTGGAATATGCACTTCGAAGACATAAACTTATGGCTCTGGTCCACAAAGAAGCACAAGGGCACA
GTGGGACAGACCACACAGTGGTGGTGCTCTCTAACCCTATACACTATATGAGCAACGACATCCC
CTACACCTTCCACCAAGACAACAGCTTCCTGTATCTTTGTGGATTCCAAGAGCCTGATAGCATT
CTGGTCCTTCAGAGCTGCTCTGGGAAGCAGTTACCATCCCATAAGGCCATGCTTTTTGTGCCTC
GGAGAGATCCTGGTCGAGAATTGTGGGATGGCCCCCGATCTGGCACGGATGGAGCAATAGCCCT
AACTGGAGTGGATGACGCCTACCCGCTGGAAGAATTTCAGCACCTGCTACCCAAACTGAGAGCT
GAGACGAACATGGTTTGGTATGACTGGATGAAGCCTTCTCATGCACAACTTCACTCTGACTACA
TGCAGCCTCTAACTGAAGCCAAAGCCACGAGCAAGAACAAGGTTCGGAGTGTCCAGCACCTGAT
ACAGCACCTGCGGCTAATTAAGTCTCCTGCAGAAATTAAGAGAATGCAGATTGCTGGGAAGCTG
ACATCAGAGGCTTTCATAGAGACCATGTTTGCCAGTAAAGCTCCAGTAGACGAAGCCTTTCTTT
ATGCGAAGTTTGAATTTGAGTGCCGTGCCCGAGGTGCCGACATCTTAGCCTACCCCCCTGTGGT
TGCAGGCGGTAATCGCTCCAACACTCTGCACTATGTGAAAAATAACCAGCTCATCAAGGATGGT
GAAATGGTGCTTCTTGATGGAGGTTGTGAGTCTTCCTGCTATGTGAGTGACATTACCAGGACGT
GGCCCGTCAATGGCAGATTCACCGCACCTCAGGCAGAGCTCTATGAAGCTGTTCTAGAAATCCA
AAAAGCTTGCTTGACACTGTGCTCCCCTGGGACAAGCTTGGAGAACATCTACAGCATGATGCTG
ACACTGATGGGACAGAAGCTTAAGGATCTGGGGATCATAAAGACCAGCAAGGAAAGCGCCTTCA
AGGCTGCTCGAAAATACTGTCCTCATCACGTGGGCCATTACCTCGGGATGGATGTCCATGACAC
TCCAGACATGCCTCGTTCACTCCCTCTGCAGCCTGGTATGGTGATCACGGTTGAACCAGGCATT
TATATCCCAGAGGGTGACACAGATGCCCCAGAGAAGTTTCGAGGTCTCGGAGTTCGGATTGAGG
ATGATGTAGTGGTGACTCAGGACTCACCTCTTATCCTTTCTGCAGACTGTCCCAAGGAGGTGAA
TGACATTGAGCAGATCTGCAGCAGGACCTCCTGACCACAGCTGTAGCACACGTGCTCCCAGGTT
CAAGACTGGCGTCCTTGCCTACTCGAGTCATTAGTGTCTCTGTGGGGATTAGCTACAGCTTCCA
TGGGAACTGCACAGCCAATGAGTGAGGACATTTTCATATTAAGTAGATTTAAATCTGGAAACGT
GGACTCTGGAATAATCTGTTACTAGGACTGTAGTGACGTTAATTCTGAGAAGTTAATGATCCAG
AAAGTTTAACATGTGACTGTAAAGTAAGGGTGCAGTTATGTGCACCCCTGCATTCTGGTTAACA
CATTTCAACAGAAAACTCTCTTCGTCCCTTTCTGCACTTCTGAGATCCACTTAACTTCCTAACA
TGCTTGTGTGAAGCCGCATGTTTAACTTCTCACCAAAGTTTGAGCCTATGCTAAAGGCTACCAG
TTAATGTTTGCGGTGGTCTTACTTACTTGCCATGGCCTCCGCCTCCTGGTCCAAGTTCTCCACA
CCCACTGGGATCTCTTGGGCCTCAGGGAGCACAGGCGTCTCAGCCAGAATACAGCAGCACAGCA
GCACAGCAGCACAGCCCACCAACAAGAGTCTTGGATCTTTCTTGCCGTTTGATTGCCCAGGACC
TGGAAAGTGTCTAGGCTCTTCTAGGGAAGAAAATGAAAGAGAAAGAAAAGTGTCTACGTGTCTC
CACATGTCCAGACCTTGAGCTCTGTTTTCTTCAGTTTAAAGGAGATTTTTTTTTTTAAATGTCC
ACCTTCCTCTCTTTCATAGATTCTTTTCTTAGGAAACATTGTCACTACGTGCCTCAAGTCCTTC
ATAAGTTGCTGTGCTTTGAGAGACAGGATCTTAGGTAGCCCAGGCTGGCCTCAAACTCATTATA
CAAATATTGCTGGGGGGTTGGGGATTTAGCTCAGTGGTAGAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAA

hide sequence

RefSeq Acc Id:

XM_006242121 ⟹ XP_006242183

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	114,820,213 - 114,858,934 (+)	NCBI
mRatBN7.2	7	112,940,068 - 112,978,793 (+)	NCBI
Rnor_6.0	7	122,651,216 - 122,686,983 (+)	NCBI
Rnor_5.0	7	122,612,798 - 122,661,434 (+)	NCBI

Sequence:

show sequence

AATTCCCGCTGGGAAGTCTGCTGACACTCAGGAAATGCAGCTCACCACTGAAACACACAAGAAA
TCAGAGTTTTTCAAAGCTGTAAGGGGAGGTGACACCAGGGCTATCTCAGGTGGAATATGCACTT
CGAAGACATAAACTTATGGCTCTGGTCCACAAAGAAGCACAAGGGCACAGTGGGACAGACCACA
CAGTGGTGGTGCTCTCTAACCCTATACACTATATGAGCAACGACATCCCCTACACCTTCCACCA
AGACAACAGCTTCCTGTATCTTTGTGGATTCCAAGAGCCTGATAGCATTCTGGTCCTTCAGAGC
TGCTCTGGGAAGCAGTTACCATCCCATAAGGCCATGCTTTTTGTGCCTCGGAGAGATCCTGGTC
GAGAATTGTGGGATGGCCCCCGATCTGGCACGGATGGAGCAATAGCCCTAACTGGAGTGGATGA
CGCCTACCCGCTGGAAGAATTTCAGCACCTGCTACCCAAACTGAGAGCTGAGACGAACATGGTT
TGGTATGACTGGATGAAGCCTTCTCATGCACAACTTCACTCTGACTACATGCAGCCTCTAACTG
AAGCCAAAGCCACGAGCAAGAACAAGGTTCGGAGTGTCCAGCACCTGATACAGCACCTGCGGCT
AATTAAGTCTCCTGCAGAAATTAAGAGAATGCAGATTGCTGGGAAGCTGACATCAGAGGCTTTC
ATAGAGACCATGTTTGCCAGTAAAGCTCCAGTAGACGAAGCCTTTCTTTATGCGAAGTTTGAAT
TTGAGTGCCGTGCCCGAGGTGCCGACATCTTAGCCTACCCCCCTGTGGTTGCAGGCGGTAATCG
CTCCAACACTCTGCACTATGTGAAAAATAACCAGCTCATCAAGGATGGTGAAATGGTGCTTCTT
GATGGAGGTTGTGAGTCTTCCTGCTATGTGAGTGACATTACCAGGACGTGGCCCGTCAATGGCA
GATTCACCGCACCTCAGGCAGAGCTCTATGAAGCTGTTCTAGAAATCCAAAAAGCTTGCTTGAC
ACTGTGCTCCCCTGGGACAAGCTTGGAGAACATCTACAGCATGATGCTGACACTGATGGGACAG
AAGCTTAAGGATCTGGGGATCATAAAGACCAGCAAGGAAAGCGCCTTCAAGGCTGCTCGAAAAT
ACTGTCCTCATCACGTGGGCCATTACCTCGGGATGGATGTCCATGACACTCCAGACATGCCTCG
TTCACTCCCTCTGCAGCCTGGTATGGTGATCACGGTTGAACCAGGCATTTATATCCCAGAGGGT
GACACAGATGCCCCAGAGAAGTTTCGAGGTCTCGGAGTTCGGATTGAGGATGATGTAGTGGTGA
CTCAGGACTCACCTCTTATCCTTTCTGCAGACTGTCCCAAGGAGGTGAATGACATTGAGCAGAT
CTGCAGCAGGACCTCCTGACCACAGCTGTAGCACACGTGCTCCCAGGTTCAAGACTGGCGTCCT
TGCCTACTCGAGTCATTAGTGTCTCTGTGGGGATTAGCTACAGCTTCCATGGGAACTGCACAGC
CAATGAGTGAGGACATTTTCATATTAAGTAGATTTAAATCTGGAAACGTGGACTCTGGAATAAT
CTGTTACTAGGACTGTAGTGACGTTAATTCTGAGAAGTTAATGATCCAGAAAGTTTAACATGTG
ACTGTAAAGTAAGGGTGCAGTTATGTGCACCCCTGCATTCTGGTTAACACATTTCAACAGAAAA
CTCTCTTCGTCCCTTTCTGCACTTCTGAGATCCACTTAACTTCCTAACATGCTTGTGTGAAGCC
GCATGTTTAACTTCTCACCAAAGTTTGAGCCTATGCTAAAGGCTACCAGTTAATGTTTGCGGTG
GTCTTACTTACTTGCCATGGCCTCCGCCTCCTGGTCCAAGTTCTCCACACCCACTGGGATCTCT
TGGGCCTCAGGGAGCACAGGCGTCTCAGCCAGAATACAGCAGCACAGCAGCACAGCAGCACAGC
CCACCAACAAGAGTCTTGGATCTTTCTTGCCGTTTGATTGCCCAGGACCTGGAAAGTGTCTAGG
CTCTTCTAGGGAAGAAAATGAAAGAGAAAGAAAAGTGTCTACGTGTCTCCACATGTCCAGACCT
TGAGCTCTGTTTTCTTCAGTTTAAAGGAGATTTTTTTTTTAAATGTCCACCTTCCTCTCTTTCA
TAGATTCTTTTCTTAGGAAACATTGTCACTACGTGCCTCAAGTCCTTCATAAGTTGCTGTGCTT
TGAGAGACAGGATCTTAGGTAGCCCAGGCTGGCCTCAAACTCATTATACAAATATTGCTGGGGG
GTTGGGGATTTAGCTCAGTGGTAGAAAAAAAAAGAAAAAATATTGCTGGCCTCAAAGTATTGAT
CTTCCTGTACCATGGCCAGTTTACTCTGTGCGTGTGCGTTTCTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGTTCTTTTTTTCGGAGCTGGGGACCGAACCCAGG
GCCTTGTGCTTCCTAGGTAAGCGCTCTACCACTGAGCTAAATCCCCAGCCCCACGTGTGTGTTT
CTTAACAAGGTTTCTCTCTGTAGCTCTGGCTATCCTGGAACACGATTTATTGACCAGGTTGGCC
TCAAACTCTCAGAGATCTGTCTCCTTCTGCCTCTCTAAATGTTGGGATTAAAAACATTATCTTC
CACCACTCAGTTCTTTATAGGTCCTTAATCCACATAGCTACTTGCAACCATGTATTGTCAAAAT
CAGTGTGATGCCTCTATTTCCCCTTCTTTTCTTCTCTGCCACCTCCTATGGTGTCTCCCCTGGC
ATGTGGAGAACTCAGTGTGGGCGTGGGGGCTAGTGCCTGTAGCTCAGCATGCTGAGTGCAGAGT
CAGGAATCTTGTCATCAGGTCAAAGCCCAGACCAGCCTGGTCTACATAGCAAGCCATAAGCTAT
CCATGGCTATATGGTGAGGCCCTACGTAAAAATTAAGACAAAACAAAAAGTACTACAAGCTTGT
GTCAGACACCTGTACTACCAATAAAATTAAATATGTGGAGTGCACTCAGCAGTTGTGAGTACCC
TATGGCCCACCTATGGAGTGCACTCTGTAATTGTGAGTACCTTATGGCCCACCTCTGCTCTAAT
GCTAGGGATGGCAAGGCAAGGCAGAGTCATGTTCCTTCCCTAAACACAGCATCAGCTTCAGTTG
TACAGCCCAGATTGCAAGGTGAGCAAGTCAGGGTGAGATTAACACAGATGGTTGATTCAAAAGC
TTGCATGAGCCGGGCCCAGTCCTTTAGCACTTGAAGCAGGCAGATCTCTGAGTTCAAAGCCAGC
CTGATCTTCAGATCGAGTTCCAGAACAGTCAGGACTACACAGAGAAATCTTGTCTCAAAAATAA
AATAAGCTTATATGATAGAGAGAAGCCCTAAGAGCTAGTGTGTTAACTTCTTTTAAATCTGAGT
ATGTGTAGACCCATGATAAACAAAACATGCCAACTATTACAACATGAATTCAAGGGTTTCGTGG
GATCTGCCCCCACCTCCCATGTTTCTGTTACGGAAGTGCAAGCTAGAAGATTAGCAAGCAGTCC
CTGCAGTGCGGGTGGCTGGCACATCTTAGAATTCACAGTACACCTAGAAACCAGCAGGGAACAA
TGGTAGTGTGAGAGGTAAGCACTGGGACACAAATGGCCCTCTGCTTATCCACAGGGCCAGCCTT
ATCCATCTCTCTTGAGGGCTGCTGCAGTGGAGGCTGCCCACCCAGAGTCTGTCCTTTCTGCCTG
CCATCCATCTGGGTCTCAGACCTAACCTACTTTCTAAAGCAGGAAGAATAAATCCATTATCAGG
CTTCTCACCCACCTGACTTCTGTGTACAAACAGCCTTCCCTTGGAGTGACTTTCCTTTCTTTCT
GTAAGTCGTCATCTATAGTTCTCACTACAGACTTCCTAGCTGAAAGTCTGCATTGCTTTTATGT
ATAGCACAGTTGGAGAGGAAACTGACTTCTGCTTACATTACAGTCAAGGTCTGGAGATGTTACT
GATGGTTAGGGTGACTTTGATGGAATTCTGGTGAATTTAGTCCATGGTCCAACATGCTACCCAT
TGAATCCCAGATTAACCTTGGCATCCAGACATTTCGGTTTGACTATTAAAACCATCCAGAAAAC
AATGGAGATGCCTCATCTGCCTCAGTGTGCCAGGCTGACCTCGCTGGGATTATTGGTGCACCAG
CCCGTACAGGAAGACTCATGACCAAGCAGTCACACAGCATAACCACTGTGCACCATGTTTCTAG
AGTCAGTGTTTGTGCACGTGTGCTCTGGTCTTCCCTCTTGAAGTCTTTTCACCTGTCAACCTGC
CATCTGGGGTTTGGTTTGGTTTGGTTTGGTTTGATAGTCTCTCCTGGAATTCACTCTGTAGACC
AGACTGCTCTCATACT

hide sequence

RefSeq Acc Id:

XM_039079904 ⟹ XP_038935832

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	114,820,218 - 114,858,934 (+)	NCBI
mRatBN7.2	7	112,926,154 - 112,978,789 (+)	NCBI

RefSeq Acc Id:

XM_039079905 ⟹ XP_038935833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	114,831,173 - 114,858,934 (+)	NCBI
mRatBN7.2	7	112,951,028 - 112,978,793 (+)	NCBI

RefSeq Acc Id:

XM_063264263 ⟹ XP_063120333

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	114,817,720 - 114,858,934 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001124054	(Get FASTA)	NCBI Sequence Viewer
	XP_006242183	(Get FASTA)	NCBI Sequence Viewer
	XP_038935832	(Get FASTA)	NCBI Sequence Viewer
	XP_038935833	(Get FASTA)	NCBI Sequence Viewer
	XP_063120333	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68759	(Get FASTA)	NCBI Sequence Viewer
	B5DEQ3	(Get FASTA)	NCBI Sequence Viewer
	EDM15723	(Get FASTA)	NCBI Sequence Viewer
	EDM15724	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000082871

RefSeq Acc Id:

NP_001124054 ⟸ NM_001130582

- UniProtKB:

B5DEQ3 (UniProtKB/Swiss-Prot), A0A8I6GA16 (UniProtKB/TrEMBL), A6HSZ7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSLLSTPRLVPVIARLRGLSGCMSCLQRRYSLQPVPVKEIPNRYLGQPSPVTHPHLLRPGEVT
PGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQ
EPDSILVLQSCSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDDAYPLEEFQHLL
PKLRAETNMVWYDWMKPSHAQLHSDYMQPLTEAKATSKNKVRSVQHLIQHLRLIKSPAEIKRMQ
IAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQ
LIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENI
YSMMLTLMGQKLKDLGIIKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVIT
VEPGIYIPEGDTDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEVNDIEQICSRTS

hide sequence

RefSeq Acc Id:	XP_006242183 ⟸ XM_006242121
- Peptide Label:	isoform X2
- UniProtKB:	B5DEQ3 (UniProtKB/Swiss-Prot), A6HSZ9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALVHKEAQGHSGTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQSCSGKQ LPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDDAYPLEEFQHLLPKLRAETNMVWYDWM KPSHAQLHSDYMQPLTEAKATSKNKVRSVQHLIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMF ASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCE SSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMGQKLKDL GIIKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEGDTDAP EKFRGLGVRIEDDVVVTQDSPLILSADCPKEVNDIEQICSRTS hide sequence

Ensembl Acc Id:

ENSRNOP00000061709 ⟸ ENSRNOT00000068666

RefSeq Acc Id:	XP_038935832 ⟸ XM_039079904
- Peptide Label:	isoform X2
- UniProtKB:	B5DEQ3 (UniProtKB/Swiss-Prot), A6HSZ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038935833 ⟸ XM_039079905
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000094221 ⟸ ENSRNOT00000115368

Ensembl Acc Id:

ENSRNOP00000082871 ⟸ ENSRNOT00000111293

RefSeq Acc Id:	XP_063120333 ⟸ XM_063264263
- Peptide Label:	isoform X1
- UniProtKB:	B5DEQ3 (UniProtKB/Swiss-Prot)

Ensembl Acc Id:

ENSRNOP00000105591 ⟸ ENSRNOT00000154702

Protein Domains

Aminopeptidase P N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DEQ3-F1-model_v2	AlphaFold	B5DEQ3	1-506	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695509

Promoter ID:

EPDNEW_R6034

Type:

multiple initiation site

Name:

Xpnpep3_1

Description:

X-prolyl aminopeptidase 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	122,636,275 - 122,636,335	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589063	AgrOrtholog
BioCyc Gene	G2FUF-32679	BioCyc
Ensembl Genes	ENSRNOG00000019196	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000111293	ENTREZGENE
Gene3D-CATH	3.40.350.10	UniProtKB/Swiss-Prot
	3.90.230.10	UniProtKB/Swiss-Prot
InterPro	Aminopep_P_N	UniProtKB/Swiss-Prot
	Creatin/AminoP/Spt16_NTD	UniProtKB/Swiss-Prot
	Creatinase/aminopeptidase-like	UniProtKB/Swiss-Prot
	Pept_M24	UniProtKB/Swiss-Prot
	X-Pro_dipept-like	UniProtKB/Swiss-Prot
KEGG Report	rno:685823	UniProtKB/Swiss-Prot
NCBI Gene	685823	ENTREZGENE
PANTHER	XAA-PRO AMINOPEPTIDASE 3	UniProtKB/Swiss-Prot
	XAA-PRO AMINOPEPTIDASE 3	UniProtKB/Swiss-Prot
Pfam	AMP_N	UniProtKB/Swiss-Prot
	Peptidase_M24	UniProtKB/Swiss-Prot
PhenoGen	Xpnpep3	PhenoGen
RatGTEx	ENSRNOG00000019196	RatGTEx
SMART	AMP_N	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF53092	UniProtKB/Swiss-Prot
	SSF55920	UniProtKB/Swiss-Prot
UniProt	A0A8I6AJ36_RAT	UniProtKB/TrEMBL
	A0A8I6GA16	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L6E7_RAT	UniProtKB/TrEMBL
	A6HSZ7	ENTREZGENE, UniProtKB/TrEMBL
	A6HSZ9	ENTREZGENE, UniProtKB/TrEMBL
	B5DEQ3	ENTREZGENE
	G3V9W4_RAT	UniProtKB/TrEMBL
	XPP3_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-13	Xpnpep3	X-prolyl aminopeptidase 3	Xpnpep3	X-prolyl aminopeptidase 3, mitochondrial	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-02-04	Xpnpep3	X-prolyl aminopeptidase 3, mitochondrial	Xpnpep3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-08	Xpnpep3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative	LOC685823	similar to CG9581-PA	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC685823	similar to CG9581-PA			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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