Mmut (methylmalonyl-CoA mutase) - Rat Genome Database

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Gene: Mmut (methylmalonyl-CoA mutase) Rattus norvegicus
Analyze
Symbol: Mmut
Name: methylmalonyl-CoA mutase
RGD ID: 1587662
Description: Predicted to enable several functions, including cobalamin binding activity; methylmalonyl-CoA mutase activity; and protein homodimerization activity. Predicted to be involved in homocysteine metabolic process; propionate metabolic process, methylmalonyl pathway; and succinyl-CoA biosynthetic process. Predicted to act upstream of or within post-embryonic development. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency. Orthologous to human MMUT (methylmalonyl-CoA mutase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301276; LOC688517; methylmalonyl CoA mutase; methylmalonyl-CoA mutase, mitochondrial; methylmalonyl-Coenzyme A mutase; Mut; rCG43751-like; similar to Methylmalonyl-CoA mutase, mitochondrial precursor (MCM) (Methylmalonyl-CoA isomerase)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8927,425,935 - 27,454,202 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl927,425,935 - 27,454,342 (-)EnsemblGRCr8
mRatBN7.2919,928,720 - 19,956,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl919,928,727 - 19,957,046 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx928,500,013 - 28,528,223 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0933,574,572 - 33,602,776 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0931,883,366 - 31,911,544 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0923,323,934 - 23,352,144 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl923,323,936 - 23,352,668 (-)Ensemblrn6Rnor6.0
Rnor_5.0922,182,975 - 22,211,162 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4916,065,495 - 16,093,956 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera917,606,384 - 17,634,555 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
(-)-citrinin  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
adefovir  (ISO)
aflatoxin B1  (ISO)
amiodarone  (EXP)
aristolochic acid A  (ISO)
atazanavir sulfate  (ISO)
Azoxymethane  (ISO)
Benoxacor  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
furan  (EXP)
geneticin  (ISO)
gentamycin  (EXP,ISO)
glafenine  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
ivermectin  (ISO)
L-ethionine  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
nefazodone  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
phlorizin  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tartrazine  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
mitochondrial matrix  (IEA,ISO)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Long-term rescue of a lethal murine model of methylmalonic acidemia using adeno-associated viral gene therapy. Chandler RJ and Venditti CP, Mol Ther. 2010 Jan;18(1):11-6. doi: 10.1038/mt.2009.247. Epub 2009 Oct 27.
2. Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle. Chandler RJ, etal., BMC Med Genet. 2007 Oct 15;8:64.
3. Molecular Genetic Characterization of 151 Mut-Type Methylmalonic Aciduria Patients and Identification of 41 Novel Mutations in MUT. Forny P, etal., Hum Mutat. 2016 Aug;37(8):745-54. doi: 10.1002/humu.23013. Epub 2016 May 23.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14555645   PMID:14651853   PMID:18614015   PMID:19699272   PMID:20031578   PMID:20876572   PMID:28101778   PMID:28497574   PMID:31056463  


Genomics

Comparative Map Data
Mmut
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8927,425,935 - 27,454,202 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl927,425,935 - 27,454,342 (-)EnsemblGRCr8
mRatBN7.2919,928,720 - 19,956,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl919,928,727 - 19,957,046 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx928,500,013 - 28,528,223 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0933,574,572 - 33,602,776 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0931,883,366 - 31,911,544 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0923,323,934 - 23,352,144 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl923,323,936 - 23,352,668 (-)Ensemblrn6Rnor6.0
Rnor_5.0922,182,975 - 22,211,162 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4916,065,495 - 16,093,956 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera917,606,384 - 17,634,555 (-)NCBICelera
Cytogenetic Map9q13NCBI
MMUT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38649,430,360 - 49,463,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl649,430,360 - 49,463,321 (-)Ensemblhg38GRCh38
GRCh37649,398,073 - 49,430,966 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36649,506,950 - 49,538,990 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34649,506,956 - 49,538,811NCBI
Celera650,954,278 - 50,987,247 (-)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef649,126,994 - 49,159,962 (-)NCBIHuRef
CHM1_1649,401,109 - 49,434,080 (-)NCBICHM1_1
T2T-CHM13v2.0649,272,390 - 49,305,330 (-)NCBIT2T-CHM13v2.0
Mmut
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391741,245,576 - 41,272,880 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1741,245,576 - 41,272,879 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381740,934,685 - 40,961,990 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1740,934,685 - 40,961,988 (+)Ensemblmm10GRCm38
MGSCv371741,071,634 - 41,098,938 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361740,398,258 - 40,425,133 (+)NCBIMGSCv36mm8
Celera1744,347,903 - 44,375,209 (+)NCBICelera
Cytogenetic Map17B2NCBI
cM Map1719.55NCBI
Mmut
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554118,363,142 - 8,399,216 (+)Ensembl
ChiLan1.0NW_0049554118,363,142 - 8,397,839 (+)NCBIChiLan1.0ChiLan1.0
MMUT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2563,921,672 - 63,954,654 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1659,786,396 - 59,819,418 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0649,007,500 - 49,040,470 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1650,269,644 - 50,302,593 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl650,269,644 - 50,302,593 (-)EnsemblpanPan2panpan1.1
MMUT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11217,306,074 - 17,339,921 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1217,307,522 - 17,339,897 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1217,207,742 - 17,239,948 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01217,803,522 - 17,836,150 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1217,791,961 - 17,836,003 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11217,323,580 - 17,355,905 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01217,428,613 - 17,461,241 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01217,558,439 - 17,590,821 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mmut
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494652,718,554 - 52,751,973 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647611,208,267 - 11,241,648 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647611,208,251 - 11,241,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMUT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl743,597,246 - 43,624,671 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1743,597,313 - 43,624,603 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2750,107,559 - 50,128,711 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMUT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11722,922,262 - 22,957,742 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1722,922,307 - 22,957,879 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604449,420,412 - 49,455,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmut
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479914,404,662 - 14,433,632 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479914,404,873 - 14,433,803 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mmut
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1494,919,182 - 94,944,594 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mmut
192 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:9
Count of miRNA genes:9
Interacting mature miRNAs:9
Transcripts:ENSRNOT00000075279
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)9131250552Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9141763315Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9671488829567695Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)92103143049025574Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000075279   ⟹   ENSRNOP00000064363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl927,425,935 - 27,454,342 (-)Ensembl
mRatBN7.2 Ensembl919,928,727 - 19,957,046 (-)Ensembl
Rnor_6.0 Ensembl923,323,936 - 23,352,668 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097764   ⟹   ENSRNOP00000083975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl927,425,935 - 27,453,360 (-)Ensembl
mRatBN7.2 Ensembl919,928,727 - 19,955,108 (-)Ensembl
RefSeq Acc Id: NM_001399409   ⟹   NP_001386338
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8927,425,935 - 27,454,123 (-)NCBI
mRatBN7.2919,928,720 - 19,956,906 (-)NCBI
RefSeq Acc Id: XM_039084505   ⟹   XP_038940433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8927,425,939 - 27,454,020 (-)NCBI
mRatBN7.2919,929,110 - 19,956,804 (-)NCBI
RefSeq Acc Id: XM_039084506   ⟹   XP_038940434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8927,433,089 - 27,454,202 (-)NCBI
mRatBN7.2919,935,876 - 19,956,985 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001386338 (Get FASTA)   NCBI Sequence Viewer  
  XP_038940433 (Get FASTA)   NCBI Sequence Viewer  
  XP_038940434 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18677 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064363
  ENSRNOP00000064363.2
  ENSRNOP00000083975.2
Ensembl Acc Id: ENSRNOP00000064363   ⟸   ENSRNOT00000075279
RefSeq Acc Id: XP_038940433   ⟸   XM_039084505
- Peptide Label: isoform X1
- UniProtKB: A6JJ55 (UniProtKB/TrEMBL),   A0A8I6A0B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940434   ⟸   XM_039084506
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000083975   ⟸   ENSRNOT00000097764
RefSeq Acc Id: NP_001386338   ⟸   NM_001399409
- UniProtKB: A6JJ55 (UniProtKB/TrEMBL),   A0A8I6A0B2 (UniProtKB/TrEMBL)
Protein Domains
B12-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZKG1-F1-model_v2 AlphaFold D3ZKG1 1-833 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587662 AgrOrtholog
BioCyc Gene G2FUF-28087 BioCyc
BioCyc Pathway PROPIONMET-PWY [propanoyl CoA degradation I] BioCyc
BioCyc Pathway Image PROPIONMET-PWY BioCyc
Ensembl Genes ENSRNOG00000050843 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075279 ENTREZGENE
  ENSRNOT00000075279.4 UniProtKB/TrEMBL
  ENSRNOT00000097764.2 UniProtKB/TrEMBL
Gene3D-CATH Cobalamin-binding domain UniProtKB/TrEMBL
  Methylmalonyl-CoA mutase UniProtKB/TrEMBL
InterPro Acid_CoA_mut_C UniProtKB/TrEMBL
  Cbl-dep_enz_cat UniProtKB/TrEMBL
  Cobalamin-bd UniProtKB/TrEMBL
  Cobalamin-bd_sf UniProtKB/TrEMBL
  MeMalonylCoA_mutase_a/b_cat UniProtKB/TrEMBL
  MMCoA_mutase_a_cat UniProtKB/TrEMBL
NCBI Gene 688517 ENTREZGENE
PANTHER METHYLMALONYL-COA MUTASE, MITOCHONDRIAL UniProtKB/TrEMBL
  METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED UniProtKB/TrEMBL
Pfam B12-binding UniProtKB/TrEMBL
  MM_CoA_mutase UniProtKB/TrEMBL
PhenoGen Mmut PhenoGen
PROSITE B12_BINDING UniProtKB/TrEMBL
  METMALONYL_COA_MUTASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050843 RatGTEx
Superfamily-SCOP Cbl-bd UniProtKB/TrEMBL
  Cbl-dep_enz_cat UniProtKB/TrEMBL
UniProt A0A8I6A0B2 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ55 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKG1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-02 Mmut  methylmalonyl-CoA mutase  Mut  methylmalonyl CoA mutase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Mut  methylmalonyl CoA mutase  LOC100361295  methylmalonyl-Coenzyme A mutase  Data merged from RGD:2320468 1643240 APPROVED
2011-08-02 Mut  methylmalonyl CoA mutase  Mut  methylmalonyl-Coenzyme A mutase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361295  methylmalonyl-Coenzyme A mutase      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-05 Mut  methylmalonyl-Coenzyme A mutase  LOC688517  similar to Methylmalonyl-CoA mutase, mitochondrial precursor (MCM) (Methylmalonyl-CoA isomerase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC688517  similar to Methylmalonyl-CoA mutase, mitochondrial precursor (MCM) (Methylmalonyl-CoA isomerase)  RGD1564912_predicted  similar to Mut protein (predicted)  Data merged from RGD:1564912 1643240 APPROVED
2006-11-19 LOC688517  similar to Methylmalonyl-CoA mutase, mitochondrial precursor (MCM) (Methylmalonyl-CoA isomerase)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1564912_predicted  similar to Mut protein (predicted)  LOC301276  similar to Mut protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC301276  similar to Mut protein      Symbol and Name status set to provisional 70820 PROVISIONAL