C9h2orf66 (similar to human chromosome 2 open reading frame 66) - Rat Genome Database

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Gene: C9h2orf66 (similar to human chromosome 2 open reading frame 66) Rattus norvegicus
Analyze
Symbol: C9h2orf66
Name: similar to human chromosome 2 open reading frame 66
RGD ID: 1586666
Description: Orthologous to human C2orf66 (chromosome 2 open reading frame 66); INTERACTS WITH 1-Hydroxypyrene (ortholog); acrylamide (ortholog); aristolochic acid A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC100365551; hypothetical protein LOC686030; LOC686030; uncharacterized protein C2orf66 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8963,440,494 - 63,444,210 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl963,442,741 - 63,444,089 (-)EnsemblGRCr8
mRatBN7.2955,945,806 - 55,949,855 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,948,303 - 55,949,643 (-)EnsemblmRatBN7.2
Rnor_6.0961,036,435 - 61,040,225 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0960,722,946 - 60,738,461 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4953,225,166 - 53,226,502 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera953,435,638 - 53,439,428 (-)NCBICelera
Cytogenetic Map9q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C9h2orf66
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8963,440,494 - 63,444,210 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl963,442,741 - 63,444,089 (-)EnsemblGRCr8
mRatBN7.2955,945,806 - 55,949,855 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,948,303 - 55,949,643 (-)EnsemblmRatBN7.2
Rnor_6.0961,036,435 - 61,040,225 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0960,722,946 - 60,738,461 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4953,225,166 - 53,226,502 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera953,435,638 - 53,439,428 (-)NCBICelera
Cytogenetic Map9q31NCBI
C2orf66
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382196,804,417 - 196,832,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2196,804,417 - 196,809,355 (-)Ensemblhg38GRCh38
GRCh372197,669,141 - 197,674,079 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362197,378,254 - 197,383,245 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2191,425,877 - 191,430,868 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2189,521,761 - 189,527,630 (-)NCBIHuRef
CHM1_12197,674,991 - 197,680,852 (-)NCBICHM1_1
T2T-CHM13v2.02197,288,090 - 197,315,820 (-)NCBIT2T-CHM13v2.0
Gm34066
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39154,481,731 - 54,495,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl154,482,563 - 54,495,922 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38154,442,572 - 54,456,786 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl154,443,404 - 54,456,763 (-)Ensemblmm10GRCm38
MGSCv37154,501,638 - 54,503,022 (-)MERGEMGSCv37MGSCv37mm9NCBIm37
Celera154,967,465 - 54,981,716 (-)NCBICelera
Cytogenetic Map1C1.2NCBI
CUNH2orf66
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554033,600,567 - 3,604,378 (+)NCBIChiLan1.0ChiLan1.0
C13H2orf66
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21399,424,004 - 99,439,884 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B99,438,995 - 99,448,905 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B84,048,089 - 84,055,991 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B201,949,363 - 201,951,884 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B201,949,363 - 201,951,310 (-)EnsemblpanPan2panpan1.1
C37H2orf66
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1376,403,572 - 6,407,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl376,403,548 - 6,407,323 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha377,350,789 - 7,356,240 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0376,293,422 - 6,298,868 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl376,295,814 - 6,297,663 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1376,293,023 - 6,298,472 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0376,262,642 - 6,265,833 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0376,284,397 - 6,287,994 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH2orf66
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303154,502,516 - 154,507,591 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365062,323,711 - 2,333,346 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C15H2orf66
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15100,704,641 - 100,713,581 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115100,704,142 - 100,708,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215111,764,058 - 111,768,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C10H2orf66
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11082,327,616 - 82,332,630 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1082,327,626 - 82,334,450 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040117,105,614 - 117,128,820 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in C9h2orf66
25 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
3 1 1 29 19 32 23 4 32 6 19 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000098126   ⟹   ENSRNOP00000088114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl963,442,741 - 63,444,089 (-)Ensembl
mRatBN7.2 Ensembl955,948,303 - 55,949,643 (-)Ensembl
RefSeq Acc Id: XM_063268122   ⟹   XP_063124192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8963,440,494 - 63,444,210 (-)NCBI
RefSeq Acc Id: XR_005489144
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8963,440,494 - 63,441,795 (-)NCBI
mRatBN7.2955,945,806 - 55,949,007 (-)NCBI
RefSeq Acc Id: XR_010054984
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8963,440,494 - 63,441,799 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001420272 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124192 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088114.1
Ensembl Acc Id: ENSRNOP00000088114   ⟸   ENSRNOT00000098126
RefSeq Acc Id: XP_063124192   ⟸   XM_063268122

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586666 AgrOrtholog
BioCyc Gene G2FUF-27543 BioCyc
Ensembl Genes ENSRNOG00000067303 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098126.2 UniProtKB/TrEMBL
InterPro DUF4720 UniProtKB/TrEMBL
NCBI Gene 686030 ENTREZGENE
PANTHER GENE, 34066-RELATED UniProtKB/TrEMBL
  PTHR47620 UniProtKB/TrEMBL
Pfam DUF4720 UniProtKB/TrEMBL
PhenoGen C9h2orf66 PhenoGen
RatGTEx ENSRNOG00000067303 RatGTEx
UniProt A0A8I6A4F4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C9h2orf66  similar to human chromosome 2 open reading frame 66  LOC686030  hypothetical protein LOC686030  Symbol and Name Changed 1299863 APPROVED
2013-05-24 LOC686030  hypothetical protein LOC686030  LOC100365551  hypothetical protein LOC100365551  Data merged from RGD:2318831 1643240 APPROVED
2010-05-05 LOC100365551  hypothetical protein LOC100365551      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC686030  hypothetical protein LOC686030  LOC683525  hypothetical protein LOC683525  Data merged from RGD:1585668 1643240 APPROVED
2006-11-19 LOC686030  hypothetical protein LOC686030      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683525  hypothetical protein LOC683525      Symbol and Name status set to provisional 70820 PROVISIONAL