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Gene: Tcf23 (transcription factor 23) Rattus norvegicus

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Symbol:

Tcf23

Name:

transcription factor 23

RGD ID:

1586500

Description:

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and transcription regulator inhibitor activity. Predicted to be involved in developmental process; negative regulation of muscle cell differentiation; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within decidualization and positive regulation of gene expression. Predicted to be located in euchromatin. Orthologous to human TCF23 (transcription factor 23); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC688600; rCG61335-like; similar to transcription factor 23

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TCF23 (transcription factor 23)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tcf23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tcf23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TCF23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TCF23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tcf23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TCF23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TCF23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tcf23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tcf23 (transcription factor 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SNX9 (sorting nexin 9)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Tcf23 (transcription factor 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TCF23 (transcription factor 23)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tcf23 (transcription factor 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tcf23 (transcription factor 23)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	31,117,839 - 31,126,575 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	31,120,127 - 31,125,878 (-)	Ensembl				GRCr8
mRatBN7.2	6	25,397,889 - 25,406,639 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	25,397,937 - 25,405,880 (-)	Ensembl				mRatBN7.2
Rnor_6.0	6	26,763,159 - 26,772,074 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	26,762,761 - 26,771,164 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	36,578,788 - 36,586,815 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	25,384,001 - 25,388,552 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	24,888,605 - 24,897,506 (-)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (EXP)

carbon nanotube (ISO)

choline (ISO)

chromium(6+) (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP,ISO)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dimethylarsinic acid (ISO)

dioxygen (ISO)

doxorubicin (ISO)

endosulfan (EXP)

folic acid (ISO)

gentamycin (EXP)

glyphosate (EXP)

isoprenaline (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

methylarsonic acid (ISO)

Moniliformin (ISO)

naphthalene (ISO)

ozone (ISO)

paracetamol (EXP)

pirinixic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

titanium dioxide (ISO)

tributylstannane (EXP)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

decidualization (ISO)

negative regulation of muscle cell differentiation (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of gene expression (ISO)

Cellular Component

euchromatin (ISO)

Molecular Function

protein binding (ISO)

protein dimerization activity (IEA)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

transcription regulator inhibitor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:24571987

Genomics

Comparative Map Data

Tcf23
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	31,117,839 - 31,126,575 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	31,120,127 - 31,125,878 (-)	Ensembl				GRCr8
mRatBN7.2	6	25,397,889 - 25,406,639 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	25,397,937 - 25,405,880 (-)	Ensembl				mRatBN7.2
Rnor_6.0	6	26,763,159 - 26,772,074 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	26,762,761 - 26,771,164 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	36,578,788 - 36,586,815 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	25,384,001 - 25,388,552 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	24,888,605 - 24,897,506 (-)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

TCF23
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	27,149,004 - 27,156,974 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	27,149,004 - 27,156,974 (+)	Ensembl			hg38	GRCh38
GRCh37	2	27,371,872 - 27,379,842 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	27,225,506 - 27,229,239 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	27,218,248 - 27,222,122 (+)	NCBI		Celera
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	27,113,796 - 27,117,670 (+)	NCBI		HuRef
CHM1_1	2	27,301,867 - 27,305,741 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	27,190,651 - 27,198,626 (+)	NCBI		T2T-CHM13v2.0

Tcf23
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	31,125,946 - 31,145,406 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	31,126,006 - 31,134,362 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	30,968,602 - 30,988,062 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	30,968,662 - 30,977,018 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	31,271,050 - 31,279,391 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	31,245,258 - 31,253,599 (+)	NCBI		MGSCv36	mm8
Celera	5	28,448,052 - 28,456,393 (+)	NCBI		Celera
Cytogenetic Map	5	B1	NCBI
cM Map	5	16.9	NCBI

Tcf23
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	9,123,987 - 9,127,633 (+)	Ensembl
ChiLan1.0	NW_004955469	9,123,987 - 9,130,728 (+)	NCBI	ChiLan1.0	ChiLan1.0

TCF23
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	99,358,503 - 99,366,443 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	99,362,471 - 99,370,475 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	27,148,122 - 27,152,006 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	27,237,282 - 27,241,149 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	27,237,282 - 27,241,149 (+)	Ensembl			panPan2	panpan1.1

TCF23
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	21,139,408 - 21,145,014 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	21,140,794 - 21,144,053 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	21,032,667 - 21,037,060 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	21,461,572 - 21,465,965 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	21,461,740 - 21,464,999 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	21,148,277 - 21,152,683 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	21,159,382 - 21,163,788 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	21,206,240 - 21,210,647 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tcf23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	65,441,223 - 65,447,315 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	5,395,283 - 5,398,141 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	5,395,222 - 5,398,141 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TCF23
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	111,976,845 - 111,983,790 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	111,976,848 - 111,983,879 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	118,975,334 - 118,982,436 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TCF23
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	80,459,590 - 80,466,272 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	80,461,732 - 80,465,499 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	31,675,387 - 31,681,683 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tcf23
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	9,256,670 - 9,263,332 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624738	9,256,432 - 9,262,894 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tcf23
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	23,108,080 - 23,112,520 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tcf23
13 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	28
Count of miRNA genes:	28
Interacting mature miRNAs:	28
Transcripts:	ENSRNOT00000009090
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1975879	46975879	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
8552910	Pigfal5	Plasma insulin-like growth factor 1 level QTL 5	4.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	22653889	67653889	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	3239989	48239989	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1975879	46975879	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1975879	46975879	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	44788383	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1975879	46975879	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1975879	46975879	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	26618314	86868070	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	3239989	48239989	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	3239989	48239989	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	26618314	86868070	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	1	40163351	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	30937632	75937632	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	14599473	63457687	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	16089372	61967788	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	3239989	48239989	Rat
1359023	Bp272	Blood pressure QTL 272	2.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	22288257	32981219	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	22288257	67288257	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	11	64	149	91	90	59	76	59	6	323	172	9	120	69	92	31	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001067558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003754152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC120639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000009090 ⟹ ENSRNOP00000009090

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	25,397,937 - 25,405,880 (-)	Ensembl
Rnor_6.0 Ensembl	6	26,762,761 - 26,771,164 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000155246 ⟹ ENSRNOP00000102820

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	31,120,127 - 31,125,878 (-)	Ensembl

RefSeq Acc Id:

XM_001067558 ⟹ XP_001067558

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	31,117,839 - 31,126,575 (-)	NCBI
mRatBN7.2	6	25,397,889 - 25,406,639 (-)	NCBI
Rnor_6.0	6	26,763,159 - 26,772,063 (-)	NCBI
Rnor_5.0	6	36,578,788 - 36,586,815 (-)	NCBI
RGSC_v3.4	6	25,384,001 - 25,388,552 (-)	RGD

Sequence:

show sequence

ACTCTGAGAACATACTTAGGCACAGAATCTCTTTCCATGCAGCTACAGTGTGGCTTTAAGATCT
TCTTTTTCCCTAAACTGTGTCCTTCAAGTCAGCGGATCCCACCACAACTTTCTCCTTTCCTGAT
GGGTGAGTTCCTGCAGAGAAAGGACAAGTTCCTGTGGGCTCTTTTGTGTCATCCTTGTAATGCA
AATCTAGCCTCTGCACTGGCCAGATTCAACTTCTAAAGGGCTCTGAACGGATGCTTCTGGAAGA
AGGCCTCTCTGAGACCGAGAACATCATGCTGAGAGCTAAGAGAACTTGTCCCTCATTCCGCGGG
CATCTTACCCTATTTACTGGATTTGACATTGTACTGTAAACTCAACACTTGGGGAACTGAGGCT
AAAGGACTTCCGTGTGTGCAAGGCCAGCAAGTTTCTGGTGGTGGGCGGGGTTAAAGTCCTGTAA
GTGAAACTCAGAGTCCTAAAGATGGCATCTTTCTCCTGGAAGTGTGGGAGGAAGGCCCGAGGGC
ATGGAAAGGCAGAAATTGAAATTGGGAAGCACGTTTGAGGAGTTGGGAGTGCACCCCTTGCATG
TGTTTTGGTGGAAGGAAGAAAGGCTGTAGTGGGATGCATATCGACAGTCTCTGGCACAAGGGCT
GGAGATCCAGAGCCCTAAACCGTGAACTTGAGCCCCAAACTTGAAGGGTTGGTCCATCAGAGGA
TTACTCTGTCAGGGTCGGTCATGGCATGGAAGGGCACTCTCTTCCTAACCGATCTTCCTGCCTT
CTAAGCATGGGCCTTGACCTAGGGCTTGGCCGCTCCCAGCATGCAGTGCCCCCACCCCTCAGCC
GGGACGGGAGGCAGGCGGAGGCTTTTTGCGGGGGCTGTGCTGGGTGGGCAGTTTTCCCAGAGCA
AGGAGTGAAGTAGGACTGAGTTGGCGCCAGCTCCTTCAGATACAGACATTGCTGGCTGGATGGC
CACCCTGTCAGGGCGAGCTTGAGCCCAAGGCTCCCTCGGGTACTGTGTCCCTGCTTTAGGGCCT
ACCGCTCCATACCTCAGGATAGCGGCATGTCACGGGAGGCCACAGAGGCACCAGCAATGCCGGA
AGCAGGGCGTAATAAGCCCAAGGCACGGTTGCTTCTGGGCACTGACAGGAAGAGGAGCCGCCTC
AACAGGACAAGGCAGGACCTGTGGGACGACACTAGCTGGAGCAATCACAGATTGAGCAGAGTCA
CCTCTGCCCCTCGAAGGACCAGAGCTAGGGGGACAGCTCATGGCAGGAGTGAGGCCAGCCCGGA
GAACGCAGCACGGGAACGGACTCGGGTGAAGACACTGCGTCAGGCCTTTCTGGCGCTGCAGGCT
GCTCTGCCTGCAGTACCACCTGACACCAAGCTTTCCAAGTTGGATGTGCTAGTGCTGGCCACAA
GCTACATCGCCCACCTCACCCGAACCCTCGGCCATGAGTTGCCTGGTCCTGCCTGGCCTCCCTT
CCTGCGTGGGCTCCGTTACTTGCACCCTCTTAAGAAGTGGCCCATGCGATCTCGTCTCTATGCA
GGAGGCTTGGGATGCTCTGGCCCGGAGTCCACCACAGCCGATTCCACCACAACCATCGCTACTG
ACCACAGAAGCAGGGATGCACAGCTGGGGTCTCAGGTCTCCGTAGCCACAGATAGCCTCCTTGC
CTCTCCAGTCTCTCCAGCCCTTGGTAACGAATGACCACCACCACTCATCCTGCTCTCTTAGACT
GCGACTCCGCTTAAGGACCTGGATTTTCTGCCCGCTCTGCCTGTCTTCCCCTTGACTCAGCCTT
TGGGTTTGACTCAGGCTCAAGTTTCAAGTTCAGGGTTGGCTTCCGGTAGGCAGAAGAAGCAGCA
GTAAAGACATCAGTGGTAGAGAGTTCCGAGGAGACCCAGGATGGAGTTCACGCTTGGCTCTTCT
ACGGTACTGACGGACGGGAAGTGAAAGAGAAACCGTGTTTGACGTGGTTCAAAGTCAAGTTAGG
GCATCACATCCCCTCCCCTAGGGCTCTTCAAGAAGAACACAAGAAGACAGAAATGGCTGTGCCG
GTACAGCATGGGGCTAGGACCACAGTAGCCCTGGGTGCTCATGGGCATACCAGGGGGCCTGAAG
GGCTTTTGGTAGCAGTAAGTATGAACATGTCTGGGGTCAGGTCACAAAGCCAGAGAGGAAGCTG
GAGAATGGAGTGTGGTTTTTTTCTTTAATTTCCCTACAAGATGTTTATCCAACATCAAAGAGGC
GTAGGCGAGATCAGGGTACTTCTCCCTGGAATACCATCTCACCAGTGGGCCCTCATCACCTCCT
TCCTGCACCAGGGCCCTGCAGCCCTTTCACGTCTTCCCAGCAGATGAAGCCCCAGACTTAGATG
GCTCACAAGCCAGGGACATTTAGCTAGTCCCAGCTATCTAGGGCCAGATCATCTTATCCCACAG
TCAGCTCTGCCTTCACTCAACGAAGCAGCCACTCACAGCCCTGCCTGCAGAGGACCGCAATCTC
CCCAGCTTTATCTCCTCCAAGGGCCTGAGACAGAGCGAGAGCATCTCTCCCGTGGCATAGTAAG
CAGTGTTCTCTCTCTGGTGTGTTAGAAACCTCATCTCAAGGACGTGTAAAACAAGGTGGACTTC
AGCGTGGTTCCTGCACTGTCAGCGATGGGGGCTTTACTGGTTTTGGTATAATCTGAACATTTCT
AAAGGTCAACTCCCAGGCCTGCTTCTCCCCACAGGCAGTGACGTCCCAGGCTTGCCCCAGATCC
TGGTACAAGGTGCCCAAAGTTTCCTAGAGCTTTAGCGACACTCGTCCTTGGCCCTGAAGAAATA
ACTGGAGACAAAGCTTACACTAAGGTGAGCTTCCCAAGCCAGGTCCAGTTTCAGGTTGGCCCCT
GGGTCTTAACATAGGAGGAACTGCCTTCCTCTCAAATTTCAGCAACTGAGGCCAACTAGAGTCC
CAGCAGGGTGCTCATGAGTTGAGTGGACAGGCTGGGAGGGATTGGCATCCAGGAAAAGGAGATG
GTGGGGTGACTCAGCAAGCTGGGGTGGAGATAGAAGGAAGACACAGAACGTCCCAGCCTCAGCT
GCATGTGCTGTGGGGAAGCAGCTGGGCTGTGGCTGAGAGCCATGGCGGACGGCCCCAGCCAAGG
CCAAACCCATAAATCTGCCTGGTCCCACATTTCTCCTGGGGGACCCAGAGAACTTGTGCAGGGC
TGGTCCAGCAGCTGGACGGGGCCAAGCAGGGGCAGAGACCAGGTGTGGGAGGGCAGGAGCAGTC
TTCTTCACACGACCATAAAAGTCCAGCCTGGGTGTTCTATTTTTAAAACCAAATCAACAGCAGC
GTCCCCCCGCCCTCCGTGGAGTTGAAGGGTGGTAAAAAGGAGTGTACATGATTTCTTCCCAGTC
AGTGATATACGATCTGTCTCTGGGCAGGCTGGGGACTGGCTTTGGGTACAAGCTACGAGTCCCC
TCATAGACTAAAGCATCTCCCAGTGATTGAGTAGAGTCTGATGGAGCTTGAAGTGTCCACCCTG
TCTAGACTCAAGCTTTTGCCTCATTTGGCAAACCCTTCACGGCTGACCACATAACACCGCCCTA
ATGGAGAATCTGAGGAGGGAAAAAGAAGATGAAGTTGGTAGAGGGTCAGGTAAAGAAGAACAAG
TCCCACCAGGAGGAGTATCTTGTTTTGGTTTGGTTTGGTTTGGTTTTTTGACATGACTTTCTGT
GTAGGCCAGGCTGGCTTTGAACTTGAAATCCTTCTGCCTTAGCAAGGGTTATGGGCTCACAGGC
CTTTACCACTCTGCCCAATCAGGACAAATTTCTAAATCTGTTGCCAGAGAATCTGTTTTTCCCA
CTGACCAGGCCTGGCACTGTCAAGCTGAGGTTACCTGACTGTGGGGAGGGGAACCAAAGGAAGA
CCCAGGGCATGACTGGAACCTCACTCTCCCTGCCCAGCACAATGCTTCCCTTGAGAAATACCAC
ACTGGAGATGCTGGAGACGCTGGAGATGAGGGTCTGTAAGCCAAGCCCACCCAGGAACGACCCC
TTTTGTTTCCACAGCAGAGAAAGAAAAGCATCTGCTGACTGGGAGATCTATGCTCACCCGCGCT
AGGGGCAAAGTGGTAGGAGCGTTTGGAGGCAGTAGAAGGAGCCGAACTCTGTCTCCAACAACAG
CTCCTGTTCCCTAGGACGGGCACGTACAGGGGAGAGTATGCAAAAGTTAAGGTGCATGGATGGA
CGGTGGTGTGCGGGTGCCCTGGCCCGGGAGTCGGAGGGATGGCTGCACCCTGTGAACCTAGTCC
AGTTTTCTTTCAGTCCCTCTCAAGGTGAGGTGCAGGTAGAGAGGAAGACTTCCCTGTTGCCTCC
CTCCACTCATCTGGCTGTGCTGCAAGAGATCAGTACTGAGGCTTACATGGAGCCCCGGGAGGGC
TCGTCCAGCACAGCGAAGGAGTTCCCCTTTGGAGACTGTGGGAACAGACAATGGCTAATCTTGA
CTGTCAACTTCTTTGGACTGAGAGGTGACGAGGGGGTTAGTAAAGTGGACCTTTGTGTATGAGG
ACTTTTACCTCCTGAATAGCTTAGTCCATGGATGGATTCAAAATAGGCTATTGATAAGCTGGGT
GTGGTGCTATATGCCCTTAATCCCAACATTCAGAAGGCAGAGGCAGGAGGATCTTTGTGAGTTG
AAGACCAGCCAGGCCAACCTAGTGGGTCTCAGTGGAATTGTGGACAGGCTGGAGGGAGGGGGCT
GGGGCCACGTGCTTGAGGCTGTGTATTGTCCCTGACTCTTTCCGTGTAACTGCCGCACTGCTGC
CCCATCTGCCTCGAGAAAAAAGATGTCCCTTCCACATACTCCCGATACCATGATGTTCTGCCCC
TAACCATGACACCAAAAAGCCTGTGGACTGAGCTCTCTGAGACTTTGGACCAAAATAAATCTTT
CCTACTCGACATTGTCTCTATCCAGAATTTGGTTACAGCGGTGTGGACTCTAATAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001419082	(Get FASTA)	NCBI Sequence Viewer
	XP_001067558	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM02954	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000102820
	ENSRNOP00000102820.1

RefSeq Acc Id:

XP_001067558 ⟸ XM_001067558

- Sequence:

show sequence

MSREATEAPAMPEAGRNKPKARLLLGTDRKRSRLNRTRQDLWDDTSWSNHRLSRVTSAPRRTRA
RGTAHGRSEASPENAARERTRVKTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRT
LGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSGPESTTADSTTTIATDHRSRDAQL
GSQVSVATDSLLASPVSPALGNE

hide sequence

Ensembl Acc Id:

ENSRNOP00000009090 ⟸ ENSRNOT00000009090

Ensembl Acc Id:

ENSRNOP00000102820 ⟸ ENSRNOT00000155246

Protein Domains

bHLH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A6W7-F1-model_v2	AlphaFold	D4A6W7	1-215	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1586500	AgrOrtholog
BioCyc Gene	G2FUF-38339	BioCyc
Ensembl Genes	ENSRNOG00000025736	Ensembl
	ENSRNOG00000074829	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000155246	ENTREZGENE
	ENSRNOT00000155246.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	E-box_TF_Regulators	UniProtKB/TrEMBL
	HLH_DNA-bd	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:688600	UniProtKB/TrEMBL
NCBI Gene	688600	ENTREZGENE
PANTHER	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST	UniProtKB/TrEMBL
	TRANSCRIPTION FACTOR 23	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
PhenoGen	Tcf23	PhenoGen
PROSITE	HLH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000025736	RatGTEx
	ENSRNOG00000074829	RatGTEx
SMART	HLH	UniProtKB/TrEMBL
Superfamily-SCOP	HLH_basic	UniProtKB/TrEMBL
UniProt	A0ABK0L2B0_RAT	UniProtKB/TrEMBL
	A6HA99	ENTREZGENE, UniProtKB/TrEMBL
	D4A6W7	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-05-24	Tcf23	transcription factor 23	LOC100364945	rCG61335-like	Data merged from RGD:2320021	1643240	APPROVED
2010-05-05	LOC100364945	rCG61335-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2010-03-09	Tcf23	transcription factor 23	LOC688600	similar to transcription factor 23	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC688600	similar to transcription factor 23	LOC684101	similar to transcription factor 23	Data merged from RGD:1593949	1643240	APPROVED
2006-11-20	LOC684101	similar to transcription factor 23			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC688600	similar to transcription factor 23			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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