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Gene: Gpkow (G patch domain and KOW motifs) Rattus norvegicus

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Symbol:

Gpkow

Name:

G patch domain and KOW motifs

RGD ID:

1583600

Description:

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Orthologous to human GPKOW (G-patch domain and KOW motifs); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; glafenine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

G patch domain and KOW motifs-containing protein; LOC679890; similar to G patch domain and KOW motifs

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPKOW (G-patch domain and KOW motifs)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Gpkow (G patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpkow (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPKOW (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPKOW (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpkow (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPKOW (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPKOW (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpkow (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gpkow (G-patch domain and KOW motifs)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GPKOW (G-patch domain and KOW motifs)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpkow (G patch domain and KOW motifs)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpkow (G patch domain and KOW motifs)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10324	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SPP2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	SPP2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gkow-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gkow-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gpkow	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	17,463,521 - 17,478,298 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	17,463,525 - 17,478,298 (-)	Ensembl				GRCr8
mRatBN7.2	X	14,791,601 - 14,806,384 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	14,791,610 - 14,806,384 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	19,605,743 - 19,620,476 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	20,462,644 - 20,477,377 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	16,727,810 - 16,742,543 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	15,636,567 - 15,651,332 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	15,636,563 - 15,651,332 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	16,418,016 - 16,433,060 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	26,832,382 - 26,846,629 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	14,875,812 - 14,890,681 (-)	NCBI		Celera
Cytogenetic Map	X	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

X-linked Microhydranencephaly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

5-azacytidine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bucladesine (ISO)

caffeine (ISO)

cobalt dichloride (ISO)

Cuprizon (ISO)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

folic acid (ISO)

fonofos (ISO)

FR900359 (ISO)

fulvestrant (ISO)

glafenine (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

medroxyprogesterone acetate (ISO)

methyl methanesulfonate (ISO)

N-ethyl-N-nitrosourea (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

selenium atom (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

terbufos (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

Triptolide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA processing (IEA)

mRNA splicing, via spliceosome (IBA,IEA,ISO)

RNA splicing (IEA)

Cellular Component

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

spliceosomal complex (IBA,IEA,ISO)

Molecular Function

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:21880142	PMID:25296192

Genomics

Comparative Map Data

Gpkow
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	17,463,521 - 17,478,298 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	17,463,525 - 17,478,298 (-)	Ensembl				GRCr8
mRatBN7.2	X	14,791,601 - 14,806,384 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	14,791,610 - 14,806,384 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	19,605,743 - 19,620,476 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	20,462,644 - 20,477,377 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	16,727,810 - 16,742,543 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	15,636,567 - 15,651,332 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	15,636,563 - 15,651,332 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	16,418,016 - 16,433,060 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	26,832,382 - 26,846,629 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	14,875,812 - 14,890,681 (-)	NCBI		Celera
Cytogenetic Map	X	q12	NCBI

GPKOW
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	49,113,407 - 49,123,735 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	49,113,396 - 49,123,746 (-)	Ensembl			hg38	GRCh38
GRCh37	X	48,970,345 - 48,980,085 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	48,857,289 - 48,867,023 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	48,726,594 - 48,736,328	NCBI
Celera	X	52,684,416 - 52,695,473 (+)	NCBI		Celera
Cytogenetic Map	X	p11.23	NCBI
HuRef	X	46,625,773 - 46,637,258 (-)	NCBI		HuRef
CHM1_1	X	49,001,472 - 49,012,544 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	48,525,155 - 48,536,289 (-)	NCBI		T2T-CHM13v2.0

Gpkow
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	7,563,373 - 7,576,500 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	7,563,370 - 7,576,501 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	7,697,134 - 7,710,261 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	7,697,131 - 7,710,262 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	7,274,260 - 7,287,387 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	6,854,172 - 6,867,216 (+)	NCBI		MGSCv36	mm8
Celera	X	3,760,344 - 3,773,449 (-)	NCBI		Celera
Cytogenetic Map	X	A1.1	NCBI
cM Map	X	3.47	NCBI

Gpkow
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955543	620,608 - 633,025 (-)	Ensembl
ChiLan1.0	NW_004955543	625,247 - 633,065 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPKOW
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	50,604,902 - 50,616,027 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	50,600,117 - 50,618,950 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	41,413,165 - 41,423,780 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	49,267,657 - 49,278,495 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	49,267,657 - 49,278,495 (-)	Ensembl			panPan2	panpan1.1

GPKOW
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	42,248,121 - 42,266,747 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	42,248,611 - 42,257,286 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	16,624,278 - 16,642,670 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha

Gpkow
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	34,773,387 - 34,790,689 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936721	1,011,492 - 1,031,440 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936721	1,013,776 - 1,031,018 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPKOW
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	43,177,272 - 43,191,830 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	43,177,264 - 43,192,021 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	48,025,071 - 48,039,785 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPKOW
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	46,212,415 - 46,227,315 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	46,209,373 - 46,227,250 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666076	11,779,954 - 11,790,503 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpkow
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624893	871,355 - 879,674 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624893	871,163 - 879,709 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gpkow
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	14,419,994 - 14,432,083 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gpkow
38 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	564
Count of miRNA genes:	289
Interacting mature miRNAs:	374
Transcripts:	ENSRNOT00000039000
Prediction methods:	Miranda, Pita, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	4001493	44939387	Rat
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1970440	46970440	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	8111486	53111486	Rat
634325	Bw13	Body weight QTL 13	0		body mass (VT:0001259)	body weight (CMO:0000012)	X	4001493	24470521	Rat

Markers in Region

BF397094

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	14,793,006 - 14,793,154 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	15,637,964 - 15,638,111	NCBI	Rnor6.0
Rnor_5.0	X	16,419,413 - 16,419,560	UniSTS	Rnor5.0
RGSC_v3.4	X	26,833,779 - 26,833,926	UniSTS	RGSC3.4
Celera	X	14,877,209 - 14,877,356	UniSTS
RH 3.4 Map	X	157.3	UniSTS
Cytogenetic Map	X	q13	UniSTS

RH143131

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	14,793,973 - 14,794,166 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	15,638,931 - 15,639,123	NCBI	Rnor6.0
Rnor_5.0	X	16,420,380 - 16,420,572	UniSTS	Rnor5.0
RGSC_v3.4	X	26,834,746 - 26,834,938	UniSTS	RGSC3.4
Celera	X	14,878,175 - 14,878,367	UniSTS
RH 3.4 Map	X	165.3	UniSTS
Cytogenetic Map	X	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000039000 ⟹ ENSRNOP00000031422

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	17,463,525 - 17,478,298 (-)	Ensembl
mRatBN7.2 Ensembl	X	14,791,610 - 14,806,384 (-)	Ensembl
Rnor_6.0 Ensembl	X	15,636,563 - 15,651,332 (-)	Ensembl

RefSeq Acc Id:

NM_001109381 ⟹ NP_001102851

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	17,463,525 - 17,478,298 (-)	NCBI
mRatBN7.2	X	14,791,610 - 14,806,384 (-)	NCBI
Rnor_6.0	X	15,636,567 - 15,651,332 (-)	NCBI
Rnor_5.0	X	16,418,016 - 16,433,060 (-)	NCBI
RGSC_v3.4	X	26,832,382 - 26,846,629 (-)	RGD
Celera	X	14,875,812 - 14,890,681 (-)	RGD

Sequence:

show sequence

ATTCTGGGATAGATTCTGGCGTTCCTGGGCGGCCCTTAAGGTACTAGAGTTAAACTTCCCAGCA
GGCAGAGCGCTCGCCTGGGACTCGAGCCAAGATGGCGGGCCGTGAGAGTCCGCCACCGGCTGCC
GCGTCCACAGCTCCGATTTCTTTCGGTTTCACTCGCACATCTGTCCGGAGGCGACTGGCAGACC
TCGGAGACAGCGAAGGACAGGCCCCAGAGAAGAAAGATTTCTTGGCGACTGTGGAAGGGAGGGA
GCTGCAGAGTGTGAACCCTCCAGAAGCTCCAAAGGAGCTGGTTATCCCATTGATCCAGAATGGC
TCTCGCAGGCAACTGCTGTCCAAGAACCCTAAGCCCTCAGAAACAAGCACCGTGTTGACGTCAG
ATGGTGTGTTGTCCCAGGCTGTGAAGGAACTCATTGAGGAATCCAAGAAGTCTCTGGAGGAGAG
GGAGAATGCAGGTGTTGACCCCACGCTCACTATCCCCATGATCCAGAAAGGATGTACTCCCATT
GGGGAAGGAACATACAGCGAACCTCAGGCTGAGACAGTGCCGGAAGAAGCCGACTATGAGGCAG
TGCCTGTGGAGGCCTATGGGCTGGCCATGTTGCGGGGCATGGGCTGGAAACCTGGCAAGGGCAT
CGGCAATACATTCAGTCAGGTAGTGAAGCCCCGAGTCAACTCTATAAGGCCAAAGGGCTTAGGG
CTGGGTGCCAACCTGATGGAGACTCAGGCCTTGGCCTCCACTGGCTCTCACCACCCACCAAGAC
CAGATGGGGATCGTGAGAAGGATAAGGAAGGCCAACCTCAAGGGCTGATGCATGGAGGAGCTGT
GGTGGTCCTTTCTGGCCCTTACCGGGGCCTCTATGGGAAGGTAGAAGGCCTAGATCCTGACAAT
GTACGAGCCATGGTTCGGCTGGCAGTAGGCAACCGCGTTGTGAATGTTAGTGAGTATTGCCTGC
GGCCTGTTTCCCAGCAGGAGTTTGATAGCCACACGTCGAAGCCAGGCCATGTGAGCAAAACTTC
CACAGAGCAGCAGCACAGAGCAACTGGAACAGCCTCATCAGTGAAGGCCCTACAGAATCAGGAA
GACTCAAAGAGGAGGCAGAAGGATTCAGAGAAGAAGCGGAAACACTCTCCTGACCGACGGGATG
GACCTGTGCCCAAGACTGAGAAAGCGGCGCCTAGAAACAAGCACTGGTTACACAGGGACCTACG
TGTGCGGTTCATTGACAAAGTGCACAAGGGTGGCCGCTATTATAACACCAAGATGACAATTGAA
GATGTCCTGAGCCCAGGTACTTGTGTGTGTCGGACGGATGAAGGCCGAGTTCTAGAAGGTGTGA
AAGAAGGCATGCTGGAGACCCTGGTTCCCAGGGGAGAGGGCCACCGCGTGATGGTGGTACTGGG
ACCACATGCTGGAAAGGTGGGACTTCTTCTGCGTCGGGACAGAGCACAGAGTCACGCTATGGTC
CAGCTTGGGAGAGAGAATCAGGTGGTGGAGCTCCACTATGATGCCATCTGCCAGTACATGGGCC
CCGGTGACTCAGATGAAGACTGACACATGGACCATTGCCCGTCACTCAGGCTGTCACTACTTTT
GTTACAATTTATAACATGCCAGAGGAAGATGGGAAATAATTGTTTGAGATGCAAAGATGGGGAT
GTGACTAGATAGAACAGGCTATTTACCAAAATTTAGAGCATAATAAAAACCATTTTCAATGGTG
AAAGGTTGAAATCAAAACCAGTATGTGAACTGTAAATTTGGGTGGGAACTGAGATAACAGAAGT
AGAAATACTTCGTTTCTTAACCTCATTTCCCTGCTGAAGGTGCAGGGCAAGTTAGATTACCCAC
TCAATACATAGCTCACCCTTGGAACTTAAGAACTATGAAGTCTATCCCCAAACACTATCGAATC
TGCAATGCCACATCTCAGAACAACTTCCTGAGTTTGGGTCTTGAATGGCCTTCAAAGGCCCATA
TCTTTTTTTTATAAGATTTATTGTATGTTGCTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGC
TTTATGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACTGTGAATATAAATGAAT
GCTTTCAGAGACCATGAGTGTTGAGTTCCCCTAGAGTCGAAGTTATAGGCAATTGCAAGCTGCC
TAGCATGGGTGCTAGGAACCAAACTGAGGTCCTTTGGAAGCGCAGTAAGCACTCTTAACCACTG
AGCTACCTCCCCAGCTCATATGCCACATGGTAAAGGATTTGTGCTCAAGACTGTACTACTAGCA
TATACTTTTGACCTTTGAAAAATAAAGGCCTGGGGGAGATTACTTAGGTCATGACTTAGAACCT
CTAAAACTGATCCAAATAATACCTTTCCTCCTTATAATTTAATTACGGCTGGAAGTTTGTCAGA
GGAAGGGGAAAGTAACTCTTATTCCCATTGACAACTCTAGTAGGAACATCTGTTTCATCCTTGA
TCCAGGGAAGACCTCCAGGATTGTCCCCGAGCTGATGATGCACTGAAGAGAAAGGGATACTTCT
GCCCACGAATATGATGGGTTAGTTCCAGTTTCCAAAGGAGCTAGTCACTTTAGTCCAGAACACT
GCTCAGGTTAAAGGTATTTCTGACTTATGCAGTTTCTCTGCTTACCCTAGGTACATTCTTAAAA
AAGAAAAAAAGGGGGTTGGGGATTTAGGTCAGTGGTAGAGCGCTTGCCTAGCAAACACAAGGCC
CTGGGTTCGGTCCCCAGCTCCGAAAAAAAAAAAAGGTTATTGTTGAGAATCCTGAACCTTTTTC
CTGTTCAATGGTTAGAGAAGAAAAGTCAGAGACTTAGACACAATTGTTTCTAAATCATCTCTAA
ATCATATACATACAGATGGATGATACTTGACTTAGATCTGGGCCACAGGTAAAAAGTTACCTAA
CTTGTCAGACTGTGGCACACACTAAAAACACTGAAAAGAATCGAAACACTGCAGAACAGGATGG
TACTGGTAAATGTGGCTATTGCTGGAGCTCAGTATTGGTACATTTGCCTAGCATATGTAAATCC
CTGGGTTCCACATTAGGGGGCGGGGGAGGAAATTGCTGTCTCTGTTGAACAAGGCAAACTGAAC
TCTCTGGTCAAAATGAACAGACAGAAAGATGTGAGTCACACCGAGTGCAGTGGCCCATGTCAGG
AATCTAGCACTTGAGAAGCTGAGACAGGAAAGTCTGAGCTTCACTGCCCTTTCATCAAAACCTA
AAAGGAAATGTGCTAAGTGTAGTAGCACACACCTTTGATCCTAGCACTCAGGAGACAGAAGTAG
GCAGACCTCCATAAGTGCAAAGCCAGCCTGGTTTACACAAGCTCCGGTCCAGCCAGAACTCATT
GGAAGAACCTGTCTCAAAGAAGAAATAGGAATGTGTGGCTTTTTTCCTTCCTCTTGTCCCTTTT
ATGTCTCTCTCTTACCTAATTGCTACATCTAAGACTTTGATACTGTATCACATAAGATAGGGGA
GAGTGGACATCTTGTTACTGATTTCAGAGAAAATGCTCAGTGTGTCTATATATAATATAATGTT
GGCTATAGATTTATTGTATATAGCCATTATTATTTTGACATATTTCCATGTATTCCAACAGTTT
CCAGAGCTTTTATCACAAAAATATGTTGAACTTTGTAAATGGGTTTTCAGCATTCACTGAACTA
ATTCATGCTTTTCTGTTCGTGAGTTTGTTTATATGCTGTATTCCATTTGCTGATTTATGTAAGT
TGAAACACCTTTGCCTTTTGGGAATGATGCGTACTTGGTCATAATGTGTAATCTTCCTAATATA
TTCCTAGATTCAGTTTGTAAGCATTTTGTTAGGAATTTTTTTAACGTAACATTTTTATTAACTC
TGCAGGAATTTCACATTATGCACCCTGATCACACTTCCCAGTCCTTCCATGTCGTCCCCCACCC
TACTTTGTGACCTCCCCACCAAAACAAGTTAAAATAAAAAAAATAATAACTAAAAATTAGAAAA
T

hide sequence

RefSeq Acc Id:

XM_063280299 ⟹ XP_063136369

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	17,463,521 - 17,476,914 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102851	(Get FASTA)	NCBI Sequence Viewer
	XP_063136369	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66817	(Get FASTA)	NCBI Sequence Viewer
	EDL83835	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031422
	ENSRNOP00000031422.4

RefSeq Acc Id:

NP_001102851 ⟸ NM_001109381

- UniProtKB:

G3V8Z3 (UniProtKB/TrEMBL), A6KP87 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGRESPPPAAASTAPISFGFTRTSVRRRLADLGDSEGQAPEKKDFLATVEGRELQSVNPPEAP
KELVIPLIQNGSRRQLLSKNPKPSETSTVLTSDGVLSQAVKELIEESKKSLEERENAGVDPTLT
IPMIQKGCTPIGEGTYSEPQAETVPEEADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKP
RVNSIRPKGLGLGANLMETQALASTGSHHPPRPDGDREKDKEGQPQGLMHGGAVVVLSGPYRGL
YGKVEGLDPDNVRAMVRLAVGNRVVNVSEYCLRPVSQQEFDSHTSKPGHVSKTSTEQQHRATGT
ASSVKALQNQEDSKRRQKDSEKKRKHSPDRRDGPVPKTEKAAPRNKHWLHRDLRVRFIDKVHKG
GRYYNTKMTIEDVLSPGTCVCRTDEGRVLEGVKEGMLETLVPRGEGHRVMVVLGPHAGKVGLLL
RRDRAQSHAMVQLGRENQVVELHYDAICQYMGPGDSDED

hide sequence

Ensembl Acc Id:

ENSRNOP00000031422 ⟸ ENSRNOT00000039000

RefSeq Acc Id:	XP_063136369 ⟸ XM_063280299
- Peptide Label:	isoform X1
- UniProtKB:	B2RYL0 (UniProtKB/TrEMBL)

Protein Domains

G-patch

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V8Z3-F1-model_v2	AlphaFold	G3V8Z3	1-487	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701746

Promoter ID:

EPDNEW_R12270

Type:

multiple initiation site

Name:

Gpkow_1

Description:

G patch domain and KOW motifs

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	15,651,249 - 15,651,309	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1583600	AgrOrtholog
BioCyc Gene	G2FUF-2913	BioCyc
Ensembl Genes	ENSRNOG00000022939	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000039000	ENTREZGENE
	ENSRNOT00000039000.7	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.30	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8365193	IMAGE-MGC_LOAD
InterPro	G_patch	UniProtKB/TrEMBL
	GPKOW_KOW1	UniProtKB/TrEMBL
	GPKOW_KOW2	UniProtKB/TrEMBL
	KOW	UniProtKB/TrEMBL
	Rib_L2_dom2	UniProtKB/TrEMBL
	Spp2-like	UniProtKB/TrEMBL
	Spp2/MOS2_G-patch	UniProtKB/TrEMBL
	Translation_prot_SH3-like_sf	UniProtKB/TrEMBL
KEGG Report	rno:679890	UniProtKB/TrEMBL
MGC_CLONE	MGC:188683	IMAGE-MGC_LOAD
NCBI Gene	679890	ENTREZGENE
PANTHER	G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN	UniProtKB/TrEMBL
	PTHR15818	UniProtKB/TrEMBL
Pfam	G-patch_2	UniProtKB/TrEMBL
	GPKOW_C	UniProtKB/TrEMBL
	KOW	UniProtKB/TrEMBL
PhenoGen	Gpkow	PhenoGen
PROSITE	G_PATCH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000022939	RatGTEx
SMART	G_patch	UniProtKB/TrEMBL
	KOW	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50104	UniProtKB/TrEMBL
UniProt	A6KP87	ENTREZGENE, UniProtKB/TrEMBL
	B2RYL0	ENTREZGENE, UniProtKB/TrEMBL
	G3V8Z3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-05	Gpkow	G patch domain and KOW motifs	LOC679890	similar to G patch domain and KOW motifs	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC679890	similar to G patch domain and KOW motifs	LOC682436	similar to G patch domain and KOW motifs	Data merged from RGD:1583456	1643240	APPROVED
2006-11-19	LOC679890	similar to G patch domain and KOW motifs			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC682436	similar to G patch domain and KOW motifs			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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