Advanced Search (OLGA)

Gene: Mboat4 (membrane bound ghrelin O-acyltransferase MBOAT4) Rattus norvegicus

Analyze

Symbol:

Mboat4

Name:

membrane bound ghrelin O-acyltransferase MBOAT4 (Ensembl:membrane bound O-acyltransferase domain containing 4)

RGD ID:

1566335

Description:

Enables serine O-acyltransferase activity. Involved in peptidyl-serine octanoylation. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human MBOAT4 (membrane bound O-acyltransferase domain containing 4); INTERACTS WITH amphetamine; bisphenol A; copper atom.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ghrelin O-acyltransferase; LOC306515; membrane bound O-acyltransferase domain containing 4; membrane-bound ghrelin O-acyltransferase MBOAT4; membrane-bound O-acyltransferase domain-containing protein 4; RGD1566335; similar to FKSG89

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	64,765,151 - 64,780,545 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	64,767,350 - 64,776,370 (-)	Ensembl				GRCr8
mRatBN7.2	16	58,064,178 - 58,077,523 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	58,064,840 - 58,073,139 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	63,405,256 - 63,413,553 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	66,818,911 - 66,827,210 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	62,039,520 - 62,047,820 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	61,782,699 - 61,795,414 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	61,782,797 - 61,791,091 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	61,448,445 - 61,461,147 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	61,792,310 - 61,800,604 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	56,102,887 - 56,111,181 (-)	NCBI		Celera
Cytogenetic Map	16	q12.2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloroethane (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

copper atom (EXP)

copper(0) (EXP)

dicrotophos (ISO)

lipopolysaccharide (ISO)

okadaic acid (ISO)

PCB138 (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

trichloroethene (EXP)

triptonide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid modification (IBA)

peptidyl-serine octanoylation (IDA,ISO)

protein acylation (ISO)

protein decanoylation (ISO)

protein octanoylation (ISO)

Cellular Component

endoplasmic reticulum (IEA,ISO,ISS)

endoplasmic reticulum membrane (IBA,IEA,ISO,ISS)

Golgi apparatus (IEA,ISO)

Molecular Function

acyltransferase activity (IEA)

acyltransferase activity, transferring groups other than amino-acyl groups (IEA,ISO)

O-acyltransferase activity (IEA)

serine O-acyltransferase activity (IBA,IDA,IEA,ISO)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Ghrelin octanoylation mediated by an orphan lipid transferase.	Gutierrez JA, etal., Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6320-5. doi: 10.1073/pnas.0800708105. Epub 2008 Apr 28.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18267071	PMID:18835978	PMID:19628676	PMID:20059966	PMID:20149910	PMID:21063108	PMID:26028164	PMID:29063591	PMID:35180934

Genomics

Comparative Map Data

Mboat4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	64,765,151 - 64,780,545 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	64,767,350 - 64,776,370 (-)	Ensembl				GRCr8
mRatBN7.2	16	58,064,178 - 58,077,523 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	58,064,840 - 58,073,139 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	63,405,256 - 63,413,553 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	66,818,911 - 66,827,210 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	62,039,520 - 62,047,820 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	61,782,699 - 61,795,414 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	61,782,797 - 61,791,091 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	61,448,445 - 61,461,147 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	61,792,310 - 61,800,604 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	56,102,887 - 56,111,181 (-)	NCBI		Celera
Cytogenetic Map	16	q12.2	NCBI

MBOAT4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	30,131,671 - 30,144,665 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	30,131,671 - 30,144,665 (-)	Ensembl			hg38	GRCh38
GRCh37	8	29,989,187 - 30,002,181 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	30,109,001 - 30,121,966 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	8	28,948,589 - 28,961,567 (-)	NCBI		Celera
Cytogenetic Map	8	p12	NCBI
HuRef	8	28,533,968 - 28,546,944 (-)	NCBI		HuRef
CHM1_1	8	30,191,520 - 30,204,491 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	30,410,588 - 30,423,543 (-)	NCBI		T2T-CHM13v2.0

Mboat4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	34,575,032 - 34,592,336 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	34,582,184 - 34,592,336 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	34,106,712 - 34,125,185 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	34,115,030 - 34,125,182 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	35,178,084 - 35,188,239 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	35,583,338 - 35,593,235 (+)	NCBI		MGSCv36	mm8
Celera	8	36,732,665 - 36,743,845 (+)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	20.9	NCBI

Mboat4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	6,598,667 - 6,606,277 (-)	Ensembl
ChiLan1.0	NW_004955463	6,598,667 - 6,606,277 (-)	NCBI	ChiLan1.0	ChiLan1.0

MBOAT4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	48,692,885 - 48,707,508 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	24,408,311 - 24,422,251 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	29,433,177 - 29,446,809 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	26,623,469 - 26,636,419 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	26,623,469 - 26,636,419 (-)	Ensembl			panPan2	panpan1.1

MBOAT4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	34,150,192 - 34,157,117 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	34,150,192 - 34,157,117 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	34,612,732 - 34,619,645 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	36,179,941 - 36,186,858 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	36,179,941 - 36,187,318 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	34,278,450 - 34,285,364 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	34,847,247 - 34,854,155 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	34,967,739 - 34,974,653 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mboat4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	57,297,628 - 57,305,339 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936792	59,230 - 65,945 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936792	59,230 - 65,945 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MBOAT4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	54,902,513 - 54,910,614 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	54,902,513 - 54,911,249 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	62,252,432 - 62,261,192 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MBOAT4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	28,233,302 - 28,250,810 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	28,233,429 - 28,250,325 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666052	13,857,458 - 13,871,881 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mboat4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624839	6,770,429 - 6,777,587 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624839	6,770,820 - 6,778,879 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mboat4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	52,906,060 - 52,914,245 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mboat4
150 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	107
Count of miRNA genes:	93
Interacting mature miRNAs:	95
Transcripts:	ENSRNOT00000042003
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	36928782	81928782	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	28468701	73468701	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	62414464	75736480	Rat
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	32361043	77361043	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	31058039	76058039	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	59428714	91442908	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	34398294	79398294	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	31885271	76885271	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	59428714	91442908	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	59428714	91442908	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	7	45	122	46	49	32	35	32	6	176	95	3	112	29	85	17	10	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU518497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000042003 ⟹ ENSRNOP00000046106

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	64,767,350 - 64,776,370 (-)	Ensembl
mRatBN7.2 Ensembl	16	58,064,840 - 58,073,139 (-)	Ensembl
Rnor_6.0 Ensembl	16	61,782,797 - 61,791,091 (-)	Ensembl

RefSeq Acc Id:

NM_001107317 ⟹ NP_001100787

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	64,767,350 - 64,776,370 (-)	NCBI
mRatBN7.2	16	58,064,178 - 58,073,203 (-)	NCBI
Rnor_6.0	16	61,782,797 - 61,791,091 (-)	NCBI
Rnor_5.0	16	61,448,445 - 61,461,147 (-)	NCBI
RGSC_v3.4	16	61,792,310 - 61,800,604 (-)	RGD
Celera	16	56,102,887 - 56,111,181 (-)	RGD

Sequence:

show sequence

ATGGATTGGCTCCAGTTCTTCTTTCTCCATCCTGTATCACTTTATCAAGGGGCTGCTTTCCCCT
TCGCGCTTCTGTTTAATTATCTCTGCATCACGGAATCCTTTCCCACCCGGGCCAGGTACCTCTT
TCTCCTGGCTGGAGGAGGTGTCCTGGCTTTGGCCGCCATGGGTCCCTACGCTCTGCTCATTTTC
ATCCCTGCTCTCTGTGCCGTGGCTATGATCTCCTCCCTCAGTCCACAGGAAGTCCATGGGCTGA
CTTTCTTCTTTCAGATGGGTTGGCAAACCCTGTGCCACCTGGGTCTTCACTACAAGGAGTACTA
CCTGTGTGAGCCTCCCCCTGTGAGGTTCTACATCACTCTTTCTTCCCTCATGCTCTTGACGCAG
AGAGTCACGTCTCTCTCCCTGGACATTTCTGAAGGGAAGGTGGAGGCAGCGTGGAGGGGCACCA
GGAGCAGGAGTTCTTTGTGTGAGCACCTGTGGGATGCTCTACCCTATATCAGCTATTTGCTCTT
TTTCCCTGCACTCCTGGGAGGCTCCCTGTGTTCCTTTCAGAGATTTCAGGCTTGCGTTCAAAGA
CCAAGGTCTTTGTATCCCAGTATCTCTTTCTGGGCTCTGACCTGGAGGGGTCTGCAGATCCTTG
GGCTGGAGTGCCTCAAGGTGGCGCTGAGGAGGGTGGTGAGTGCTGGCGCTGGACTGGATGATTG
CCAGCGACTGGAGTGCATCTACATCATGTGGTCCACCGCTGGGCTCTTTAAACTCACCTACTAC
TCCCACTGGATCCTGGACGACTCTCTCCTTCACGCGGCGGGCTTTGGATCTGAGGCTGGCCAGA
GGCCTGGAGAGGAGAGATACGTCCCGGATGTGGACATTTGGACATTGGAAACTACCCACAGGAT
CTCCCTGTTCGCGAGGCAGTGGAACCGAAGCACAGCTCAGTGGCTCAAGAGGCTTGTCTTCCAG
AGGAGCCGGCGCTGGCCCGTGCTGCAGACTTTTGCCTTCTCTGCCTGGTGGCACGGACTCCACC
CAGGACAGGTGTTTGGCTTCCTGTGCTGGTCTGTGATGGTGAAAGCCGACTATCTGATCCACAC
TTTTGCCAATGGATGTATCAGATCCTGGCCCCTGCGGCTGCTTTATAGATCCCTCACTTGGGCC
CACACTCAGATCATCATTGCTTACGTAATGCTGGCCGTGGAGGGCCGGAGCTTTTCCTCTCTCT
GCCGGCTGTGCTGTTCTTACAACAGTATCTTCCCTGTAACGTACTGCCTTTTGCTTTTTCTATT
AGCGAGGAGAAAACACAAGTGTAACTGA

hide sequence

RefSeq Acc Id:

XM_017600133 ⟹ XP_017455622

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	64,765,151 - 64,780,545 (-)	NCBI
mRatBN7.2	16	58,064,664 - 58,077,523 (-)	NCBI
Rnor_6.0	16	61,782,699 - 61,795,414 (-)	NCBI

Sequence:

show sequence

TCACCTGTGGGTCCTGCCGCCCTGCCTCCTGGGAAATCATTTTTTCCACTTGTCAGTGTTTACT
GCATCAAGTCTACCCTTACCCCAGCAGCCCTAACCCTCATCGTTAGTTCGCTCTACGTTTAACC
TCTAGAATCACCTTCCTCCCTAAGCCTCATCCATGGCGTTTCTTGTCAAAATCTCTTTTGAACA
TCAAATCCAGTTTTTAAACTTCTCATTACAAGCCTTTCTACGCCACATAAAAAGGCTCCGGAGA
GCCGGGGTGTGACTTCCCTAGCACAAGGGCACCACCTAGGAACTCTAGGAAGGACAGTGCGTTC
CGGTTCCGTAATGGATTGGCTCCAGTTCTTCTTTCTCCATCCTGTATCACTTTATCAAGGGGCT
GCTTTCCCCTTCGCGCTTCTGTTTAATTATCTCTGCATCACGGAATCCTTTCCCACCCGGGCCA
GGTACCTCTTTCTCCTGGCTGGAGGAGGTGTCCTGGCTTTGGCCGCCATGGGTCCCTACGCTCT
GCTCATTTTCATCCCTGCTCTCTGTGCCGTGGCTATGATCTCCTCCCTCAGTCCACAGGAAGTC
CATGGGCTGACTTTCTTCTTTCAGATGGGTTGGCAAACCCTGTGCCACCTGGGTCTTCACTACA
AGGAGTACTACCTGTGTGAGCCTCCCCCTGTGAGGTTCTACATCACTCTTTCTTCCCTCATGCT
CTTGACGCAGAGAGTCACGTCTCTCTCCCTGGACATTTCTGAAGGGAAGGTGGAGGCAGCGTGG
AGGGGCACCAGGAGCAGGAGTTCTTTGTGTGAGCACCTGTGGGATGCTCTACCCTATATCAGCT
ATTTGCTCTTTTTCCCTGCACTCCTGGGAGGCTCCCTGTGTTCCTTTCAGAGATTTCAGGCTTG
CGTTCAAAGACCAAGGTCTTTGTATCCCAGTATCTCTTTCTGGGCTCTGACCTGGAGGGGTCTG
CAGATCCTTGGGCTGGAGTGCCTCAAGGTGGCGCTGAGGAGGGTGGTGAGTGCTGGCGCTGGAC
TGGATGATTGCCAGCGACTGGAGTGCATCTACATCATGTGGTCCACCGCTGGGCTCTTTAAACT
CACCTACTACTCCCACTGGATCCTGGACGACTCTCTCCTTCACGCGGCGGGCTTTGGATCTGAG
GCTGGCCAGAGGCCTGGAGAGGAGAGATACGTCCCGGATGTGGACATTTGGACATTGGAAACTA
CCCACAGGATCTCCCTGTTCGCGAGGCAGTGGAACCGAAGCACAGCTCAGTGGCTCAAGAGGCT
TGTCTTCCAGAGGAGCCGGCGCTGGCCCGTGCTGCAGACTTTTGCCTTCTCTGCCTGGTGGCAC
GGACTCCACCCAGGACAGGTGTTTGGCTTCCTGTGCTGGTCTGTGATGGTGAAAGCCGACTATC
TGATCCACACTTTTGCCAATGGATGTATCAGATCCTGGCCCCTGCGGCTGCTTTATAGATCCCT
CACTTGGGCCCACACTCAGATCATCATTGCTTACGTAATGCTGGCCGTGGAGGGCCGGAGCTTT
TCCTCTCTCTGCCGGCTGTGCTGTTCTTACAACAGTATCTTCCCTGTAACGTACTGCCTTTTGC
TTTTTCTATTAGCGAGGAGAAAACACAAGTGTAACTGAGAGCTTTCCCTGCCCTTCATCCCTCC
CAGGCATTAAACGCTGCTTAGAAAATACCAGAGGATGCCTTGTTGAATAACGTATTTAATTTTT
TTCTTTTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100787	(Get FASTA)	NCBI Sequence Viewer
	XP_017455622	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACB05875	(Get FASTA)	NCBI Sequence Viewer
	B1Q005	(Get FASTA)	NCBI Sequence Viewer
	EDM09175	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000046106
	ENSRNOP00000046106.3

RefSeq Acc Id:

NP_001100787 ⟸ NM_001107317

- UniProtKB:

B1Q005 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MDWLQFFFLHPVSLYQGAAFPFALLFNYLCITESFPTRARYLFLLAGGGVLALAAMGPYALLIF
IPALCAVAMISSLSPQEVHGLTFFFQMGWQTLCHLGLHYKEYYLCEPPPVRFYITLSSLMLLTQ
RVTSLSLDISEGKVEAAWRGTRSRSSLCEHLWDALPYISYLLFFPALLGGSLCSFQRFQACVQR
PRSLYPSISFWALTWRGLQILGLECLKVALRRVVSAGAGLDDCQRLECIYIMWSTAGLFKLTYY
SHWILDDSLLHAAGFGSEAGQRPGEERYVPDVDIWTLETTHRISLFARQWNRSTAQWLKRLVFQ
RSRRWPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHTFANGCIRSWPLRLLYRSLTWA
HTQIIIAYVMLAVEGRSFSSLCRLCCSYNSIFPVTYCLLLFLLARRKHKCN

hide sequence

RefSeq Acc Id:	XP_017455622 ⟸ XM_017600133
- Peptide Label:	isoform X1
- UniProtKB:	B1Q005 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MDWLQFFFLHPVSLYQGAAFPFALLFNYLCITESFPTRARYLFLLAGGGVLALAAMGPYALLIF IPALCAVAMISSLSPQEVHGLTFFFQMGWQTLCHLGLHYKEYYLCEPPPVRFYITLSSLMLLTQ RVTSLSLDISEGKVEAAWRGTRSRSSLCEHLWDALPYISYLLFFPALLGGSLCSFQRFQACVQR PRSLYPSISFWALTWRGLQILGLECLKVALRRVVSAGAGLDDCQRLECIYIMWSTAGLFKLTYY SHWILDDSLLHAAGFGSEAGQRPGEERYVPDVDIWTLETTHRISLFARQWNRSTAQWLKRLVFQ RSRRWPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHTFANGCIRSWPLRLLYRSLTWA HTQIIIAYVMLAVEGRSFSSLCRLCCSYNSIFPVTYCLLLFLLARRKHKCN hide sequence

Ensembl Acc Id:

ENSRNOP00000046106 ⟸ ENSRNOT00000042003

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1Q005-F1-model_v2	AlphaFold	B1Q005	1-435	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566335	AgrOrtholog
BioCyc Gene	G2FUF-11139	BioCyc
Ensembl Genes	ENSRNOG00000030102	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000042003	ENTREZGENE
	ENSRNOT00000042003.4	UniProtKB/Swiss-Prot
InterPro	LPLAT_7/PORCN-like	UniProtKB/Swiss-Prot
	MBOAT_fam	UniProtKB/Swiss-Prot
KEGG Report	rno:306515	UniProtKB/Swiss-Prot
NCBI Gene	306515	ENTREZGENE
PANTHER	GHRELIN O-ACYLTRANSFERASE	UniProtKB/Swiss-Prot
	PORCUPINE	UniProtKB/Swiss-Prot
Pfam	MBOAT	UniProtKB/Swiss-Prot
PhenoGen	Mboat4	PhenoGen
RatGTEx	ENSRNOG00000030102	RatGTEx
UniProt	B1Q005	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Mboat4	membrane bound ghrelin O-acyltransferase MBOAT4	Mboat4	membrane bound O-acyltransferase domain containing 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Mboat4	membrane bound O-acyltransferase domain containing 4	RGD1566335_predicted	similar to FKSG89 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1566335_predicted	similar to FKSG89 (predicted)	LOC306515	similar to FKSG89	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC306515	similar to FKSG89			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message