Cisd2 (CDGSH iron sulfur domain 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cisd2 (CDGSH iron sulfur domain 2) Rattus norvegicus
Analyze
Symbol: Cisd2
Name: CDGSH iron sulfur domain 2
RGD ID: 1566242
Description: Predicted to enable 2 iron, 2 sulfur cluster binding activity and protein homodimerization activity. Predicted to be involved in autophagy of mitochondrion and regulation of autophagy. Predicted to be located in endoplasmic reticulum membrane and perinuclear endoplasmic reticulum. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Wolfram syndrome 2. Orthologous to human CISD2 (CDGSH iron sulfur domain 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDGSH iron sulfur domain-containing protein 2; CDGSH iron-sulfur domain-containing protein 2; LOC295457; RGD1566242; similar to RIKEN cDNA 1500009M05
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82226,502,517 - 226,527,325 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2226,502,517 - 226,540,080 (-)EnsemblGRCr8
mRatBN7.22223,828,937 - 223,853,768 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2223,828,937 - 223,868,946 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2231,554,428 - 231,579,029 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02229,454,165 - 229,478,768 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02224,318,946 - 224,343,554 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02240,586,754 - 240,611,560 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2240,586,754 - 240,611,560 (-)Ensemblrn6Rnor6.0
Rnor_5.02259,106,753 - 259,130,712 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42232,902,533 - 232,927,338 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2216,041,027 - 216,061,932 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2. Amr S, etal., Am J Hum Genet. 2007 Oct;81(4):673-83. Epub 2007 Aug 20.
2. Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice. Chen YF, etal., Genes Dev. 2009 May 15;23(10):1183-94. doi: 10.1101/gad.1779509.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:17376863   PMID:19580816   PMID:19946888   PMID:20010695   PMID:22658674   PMID:34740104  


Genomics

Comparative Map Data
Cisd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82226,502,517 - 226,527,325 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2226,502,517 - 226,540,080 (-)EnsemblGRCr8
mRatBN7.22223,828,937 - 223,853,768 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2223,828,937 - 223,868,946 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2231,554,428 - 231,579,029 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02229,454,165 - 229,478,768 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02224,318,946 - 224,343,554 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02240,586,754 - 240,611,560 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2240,586,754 - 240,611,560 (-)Ensemblrn6Rnor6.0
Rnor_5.02259,106,753 - 259,130,712 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42232,902,533 - 232,927,338 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2216,041,027 - 216,061,932 (-)NCBICelera
Cytogenetic Map2q43NCBI
CISD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384102,868,992 - 102,892,807 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4102,868,971 - 102,892,807 (+)Ensemblhg38GRCh38
GRCh374103,790,149 - 103,813,964 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364104,009,649 - 104,029,164 (+)NCBIBuild 36Build 36hg18NCBI36
Celera4101,089,752 - 101,113,582 (+)NCBICelera
Cytogenetic Map4q24NCBI
HuRef499,526,316 - 99,550,157 (+)NCBIHuRef
CHM1_14103,766,606 - 103,790,436 (+)NCBICHM1_1
T2T-CHM13v2.04106,183,319 - 106,207,145 (+)NCBIT2T-CHM13v2.0
Cisd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393135,112,173 - 135,129,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3135,112,173 - 135,129,686 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383135,406,412 - 135,424,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3135,406,412 - 135,423,925 (-)Ensemblmm10GRCm38
MGSCv373135,069,376 - 135,086,397 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363135,343,801 - 135,360,820 (-)NCBIMGSCv36mm8
Celera3141,820,762 - 141,837,774 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map362.55NCBI
Cisd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554965,656,686 - 5,673,529 (-)Ensembl
ChiLan1.0NW_0049554965,656,686 - 5,672,888 (-)NCBIChiLan1.0ChiLan1.0
CISD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23100,912,006 - 100,972,687 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14101,239,467 - 101,259,790 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0495,251,920 - 95,313,404 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14105,954,880 - 105,974,469 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4105,954,880 - 105,975,142 (+)EnsemblpanPan2panpan1.1
CISD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13224,257,909 - 24,274,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3224,257,994 - 24,274,064 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3217,749,212 - 17,766,034 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03224,477,615 - 24,494,434 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3224,477,713 - 24,494,855 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13224,494,845 - 24,511,655 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03224,238,087 - 24,254,903 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03215,607,865 - 15,624,939 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cisd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530117,171,568 - 17,184,110 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936520514,448 - 527,682 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936520514,747 - 527,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CISD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8118,152,227 - 118,164,689 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18118,152,580 - 118,164,695 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28127,126,872 - 127,138,883 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CISD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1750,968,061 - 50,988,725 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl750,968,111 - 50,988,714 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603729,479,400 - 29,500,029 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cisd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248305,173,411 - 5,188,098 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248305,173,410 - 5,188,123 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cisd2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1323,664,731 - 23,683,523 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cisd2
502 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:295
Count of miRNA genes:178
Interacting mature miRNAs:220
Transcripts:ENSRNOT00000074632
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2212145502231732847Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2202029709236904960Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
8693697Alc36Alcohol consumption QTL 3620.592drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2219814164239320906Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2214404877251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2214404877251712708Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2218051934251712708Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
1302789Stl26Serum triglyceride level QTL 263.10.0035blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)2206613059226891081Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2214404877251712708Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2214404877251712708Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2221088977243501206Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2203664411248664411Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2214404877251712708Rat
8693622Alc26Alcohol consumption QTL 262.40.667drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2223810546243965570Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2221270493228950743Rat

Markers in Region
RH133566  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22223,828,934 - 223,829,138 (+)MAPPERmRatBN7.2
Rnor_6.02240,586,752 - 240,586,955NCBIRnor6.0
Rnor_5.02259,106,751 - 259,106,954UniSTSRnor5.0
RGSC_v3.42232,902,531 - 232,902,734UniSTSRGSC3.4
Celera2216,041,025 - 216,041,228UniSTS
RH 3.4 Map21567.3UniSTS
Cytogenetic Map2q43UniSTS
RH137154  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22223,854,978 - 223,855,158 (+)MAPPERmRatBN7.2
Rnor_6.02240,612,766 - 240,612,945NCBIRnor6.0
Rnor_5.02259,131,918 - 259,132,097UniSTSRnor5.0
RGSC_v3.42232,928,544 - 232,928,723UniSTSRGSC3.4
Celera2216,063,138 - 216,063,317UniSTS
RH 3.4 Map21564.3UniSTS
Cytogenetic Map2q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000074632   ⟹   ENSRNOP00000066613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2226,502,517 - 226,540,080 (-)Ensembl
mRatBN7.2 Ensembl2223,828,937 - 223,868,946 (-)Ensembl
Rnor_6.0 Ensembl2240,586,754 - 240,611,560 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137682   ⟹   ENSRNOP00000105412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2226,502,517 - 226,536,744 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165513   ⟹   ENSRNOP00000102562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2226,502,517 - 226,527,325 (-)Ensembl
RefSeq Acc Id: NM_001191608   ⟹   NP_001178537
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82226,502,517 - 226,527,325 (-)NCBI
mRatBN7.22223,828,937 - 223,853,768 (-)NCBI
Rnor_6.02240,586,754 - 240,611,560 (-)NCBI
Rnor_5.02259,106,753 - 259,130,712 (-)NCBI
Celera2216,041,027 - 216,061,932 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178537 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL82257 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066613.3
  ENSRNOP00000102562
  ENSRNOP00000102562.1
  ENSRNOP00000105412.1
RefSeq Acc Id: NP_001178537   ⟸   NM_001191608
- UniProtKB: A6HVX1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066613   ⟸   ENSRNOT00000074632
Ensembl Acc Id: ENSRNOP00000105412   ⟸   ENSRNOT00000137682
Ensembl Acc Id: ENSRNOP00000102562   ⟸   ENSRNOT00000165513
Protein Domains
Iron-binding zinc finger CDGSH type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAE9-F1-model_v2 AlphaFold D4AAE9 1-135 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691769
Promoter ID:EPDNEW_R2294
Type:initiation region
Name:Cisd2_1
Description:CDGSH iron sulfur domain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02240,611,567 - 240,611,627EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566242 AgrOrtholog
BioCyc Gene G2FUF-51136 BioCyc
Ensembl Genes ENSRNOG00000048258 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074632.3 UniProtKB/TrEMBL
  ENSRNOT00000137682.1 UniProtKB/TrEMBL
  ENSRNOT00000165513 ENTREZGENE
  ENSRNOT00000165513.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.5.90 UniProtKB/TrEMBL
InterPro CISD1/2 UniProtKB/TrEMBL
  FeS-contain_CDGSH-typ UniProtKB/TrEMBL
  FeS-contain_mitoNEET_C UniProtKB/TrEMBL
  FeS-contain_mitoNEET_N UniProtKB/TrEMBL
KEGG Report rno:295457 UniProtKB/TrEMBL
NCBI Gene 295457 ENTREZGENE
PANTHER CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR13680 UniProtKB/TrEMBL
Pfam MitoNEET_N UniProtKB/TrEMBL
  zf-CDGSH UniProtKB/TrEMBL
PhenoGen Cisd2 PhenoGen
RatGTEx ENSRNOG00000048258 RatGTEx
SMART ZnF_CDGSH UniProtKB/TrEMBL
UniProt A0ABK0LB68_RAT UniProtKB/TrEMBL
  A0ABK0LTC3_RAT UniProtKB/TrEMBL
  A6HVX1 ENTREZGENE, UniProtKB/TrEMBL
  D4AAE9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Cisd2  CDGSH iron sulfur domain 2  RGD1566242_predicted  similar to RIKEN cDNA 1500009M05 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1566242_predicted  similar to RIKEN cDNA 1500009M05 (predicted)  LOC295457  similar to RIKEN cDNA 1500009M05  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC295457  similar to RIKEN cDNA 1500009M05      Symbol and Name status set to provisional 70820 PROVISIONAL