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Gene: Zfp777 (zinc finger protein 777) Rattus norvegicus

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Symbol:

Zfp777

Name:

zinc finger protein 777

RGD ID:

1566056

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of cell population proliferation; protein heterooligomerization; and regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human ZNF777 (zinc finger protein 777); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC502764; RGD1566056; similar to KIAA1285 protein; Znf777

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF777 (zinc finger protein 777)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Zfp777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Znf777 (zinc finger protein 777)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	COG8 (component of oligomeric golgi complex 8)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ZNF777 (zinc finger protein 777)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp777 (zinc finger protein 777)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ZAP1	Alliance	DIOPT (Hieranoid\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC101731011	Alliance	DIOPT (Hieranoid\|InParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	78,347,315 - 78,377,720 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	78,347,315 - 78,373,357 (-)	Ensembl				GRCr8
mRatBN7.2	4	77,016,377 - 77,044,008 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	77,016,363 - 77,047,020 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	82,228,722 - 82,252,077 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	78,003,044 - 78,026,399 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	76,444,521 - 76,467,876 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	77,684,488 - 77,710,998 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	77,684,488 - 77,706,994 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	142,354,004 - 142,379,586 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	76,142,729 - 76,165,380 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	71,963,928 - 71,986,394 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

deoxynivalenol (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

fenthion (ISO)

GSK-J4 (ISO)

lead(0) (ISO)

nitrates (ISO)

nitrofen (EXP)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

quercetin (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

negative regulation of cell population proliferation (IEA,ISO)

negative regulation of DNA-templated transcription (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA)

protein heterooligomerization (IEA,ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

transcription cis-regulatory region binding (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Zfp777
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	78,347,315 - 78,377,720 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	78,347,315 - 78,373,357 (-)	Ensembl				GRCr8
mRatBN7.2	4	77,016,377 - 77,044,008 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	77,016,363 - 77,047,020 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	82,228,722 - 82,252,077 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	78,003,044 - 78,026,399 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	76,444,521 - 76,467,876 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	77,684,488 - 77,710,998 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	77,684,488 - 77,706,994 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	142,354,004 - 142,379,586 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	76,142,729 - 76,165,380 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	71,963,928 - 71,986,394 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

ZNF777
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	149,431,363 - 149,461,062 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	149,431,363 - 149,461,062 (-)	Ensembl			hg38	GRCh38
GRCh37	7	149,128,454 - 149,158,153 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	148,759,387 - 148,788,986 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	7	143,797,705 - 143,827,305 (-)	NCBI		Celera
Cytogenetic Map	7	q36.1	NCBI
HuRef	7	143,204,999 - 143,234,504 (-)	NCBI		HuRef
CHM1_1	7	149,137,116 - 149,166,634 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	150,613,213 - 150,642,913 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	148,466,512 - 148,496,088 (-)	NCBI

Zfp777
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	47,994,594 - 48,026,963 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	48,001,122 - 48,025,845 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	48,017,660 - 48,050,004 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	48,024,188 - 48,048,911 (-)	Ensembl			mm10	GRCm38
MGSCv37	6	47,974,187 - 47,998,113 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	47,953,774 - 47,979,616 (-)	NCBI		MGSCv36	mm8
Celera	6	48,554,529 - 48,575,038 (-)	NCBI		Celera
Cytogenetic Map	6	B2.3	NCBI
cM Map	6	23.0	NCBI

Znf777
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955491	4,573,465 - 4,596,595 (-)	Ensembl
ChiLan1.0	NW_004955491	4,573,841 - 4,596,610 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZNF777
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	186,019,834 - 186,049,275 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	38,030,098 - 38,059,539 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	141,163,479 - 141,193,859 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	153,639,560 - 153,668,723 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	153,638,402 - 153,668,717 (-)	Ensembl			panPan2	panpan1.1

ZNF777
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	14,365,928 - 14,394,007 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	14,366,062 - 14,388,958 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	14,974,633 - 15,002,711 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	16,080,624 - 16,108,666 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	16,080,631 - 16,107,889 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	14,460,703 - 14,487,944 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	15,041,735 - 15,069,783 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	15,091,744 - 15,119,790 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znf777
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	7,439,233 - 7,462,431 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936527	5,440,568 - 5,464,262 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936527	5,440,584 - 5,467,252 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF777
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	55,614,730 - 55,645,523 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	18	55,614,718 - 55,645,719 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	60,941,509 - 60,971,840 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF777
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	117,990,876 - 118,021,516 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	117,988,783 - 118,019,970 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666072	13,943,293 - 13,973,371 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf777
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624800	6,426,839 - 6,455,289 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624800	6,426,149 - 6,451,041 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Znf777
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	92,837,621 - 92,865,008 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Zfp777
175 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	67
Count of miRNA genes:	58
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000038517
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	39431983	123203361	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	59753119	104753119	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	41400577	86400577	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	44425024	89425024	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
1357342	Bw40	Body weight QTL 40		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	4	74233320	119233320	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	58817672	103817672	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
70167	Bw22	Body weight QTL 22	3.1		body mass (VT:0001259)	body weight (CMO:0000012)	4	74233320	119233320	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58080146	80212111	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	71647492	116647492	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	41400603	86400603	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	75939858	140508796	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	30448961	82336920	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	65060960	127749483	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	45429897	149763204	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	51085655	113588029	Rat
2317588	Eae27	Experimental allergic encephalomyelitis QTL 27			nervous system integrity trait (VT:0010566)	percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)	4	69036742	114036742	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	40490442	117737312	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	57613339	151163960	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	57613242	102613242	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	57613242	102613242	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	35113290	80113290	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	57613242	102613242	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	58079875	82597589	Rat
2306547	Iddm38	Insulin dependent diabetes mellitus QTL 38			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	68353567	113353567	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	74169813	134199155	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	59836842	104836842	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	37269577	82269577	Rat
61406	Scwia1	Streptococcal cell wall induced arthritis QTL 1	2.3		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	4	75939858	140508796	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	45429897	149763204	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	61041057	94638356	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63245026	129846354	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	64209744	109209744	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	41400577	86400577	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	57664252	127749483	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58079875	92690793	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63224393	108224393	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	63900458	88813920	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	33538597	116185060	Rat
631671	Iddm11	Insulin dependent diabetes mellitus QTL 11	3.6	0.0012	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	59603319	80216952	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762913	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038517 ⟹ ENSRNOP00000034825

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	78,347,315 - 78,373,191 (-)	Ensembl
mRatBN7.2 Ensembl	4	77,016,363 - 77,041,205 (-)	Ensembl
Rnor_6.0 Ensembl	4	77,684,488 - 77,706,994 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113218 ⟹ ENSRNOP00000079994

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	78,347,315 - 78,373,357 (-)	Ensembl
mRatBN7.2 Ensembl	4	77,016,363 - 77,047,020 (-)	Ensembl

RefSeq Acc Id:

NM_001109348 ⟹ NP_001102818

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	78,347,315 - 78,373,558 (-)	NCBI
mRatBN7.2	4	77,016,378 - 77,042,621 (-)	NCBI
Rnor_6.0	4	77,684,488 - 77,706,994 (-)	NCBI
Rnor_5.0	4	142,354,004 - 142,379,586 (-)	NCBI
RGSC_v3.4	4	76,142,729 - 76,165,380 (-)	RGD
Celera	4	71,963,928 - 71,986,394 (-)	RGD

Sequence:

show sequence

GTCCAGCAGCTGGACATGGAGGACGACCGCTCATCACCTCTGTCATTCTCCAGAATTCCACACG
AAGAGTCTGTGCATCAGGCCCCTGCCCGGCTCCCTAGAGAAACTGTGTTCTCGTCTTGCATCCT
TCCCCCCAAAGAAATTTCTCCTTTGTCTCCCACTGCTCCCCAGCAAGCTGCCCTGCCCCAGACT
GACAGTCCTCCTAAGCAAGAGACATCCGGCCAGATGTCACATGTTCTCCAGAAAGGACCTTCAC
TCCTGTGTCCTGCCACTTCGGAGCAAGACACACCTCACCAGGTATCCCTGGCTTCCCAGGAAGA
AACTCACTCCCCTCCTTCAGCTGCTGGTCAAGGGATCCCCTTCCTCTCCCACTCCACCCACCAT
CAGGACGCTCCACTCCACTCTCCTGAAGCTCCTGAGAAAGACTCGCTGACTCTGTCACCCACAG
TTCCCGAGACCGACATGGACCCCTTGCTCCAGAGTCCCACTTTACAAAAGGACACTCCCTTCCA
TACCTCTTCTGCAGCCCAGAAGGAACAGCCACTGCCCACCGCAGAGATCACTCGCTTGGCCGTG
TGGGCTGCAGTACAAGCAGTGGAGAGGAAACTGGAGGCCCAGGCCATGCGACTACTGACTCTGG
AGAGCAGGACAGGGACAAATGAGAAGAAGATAGCAGACTGTGAGAGAACAGCTGTGGAGTTCGC
AAATCATCTGGAGAGTAAGTGGGTTGTACTGGGGACCCTGCTGCAGGAGTATGGGCTGCTGCAG
CGGCGCCTGGAGAACATGGAGAATCTGCTAAAAAACAGAAATTTCTGGATCCTGCGGCTACCCC
CAGGCAGCAACGGAGAAGTTCCCAAGGTTCCTGTCACATTTGATGATGTCGCCGTCCATTTCTC
TGAGCAGGAATGGGGAAATCTCTCTGAGTGGCAAAAGGAGCTCTACAAGAATGTAATGAGGGGC
AACTATGAGTCTCTGGTCTCTATGGACTATGCAATATCCAAACCAGACCTGATGTCACAGATGG
AGCGTGGCGAGAGGCCAGCCATGCAGGAGCAAGAGGACTCTGAGGAGGGCGAGACGCCCACGGA
TCCCAGTGCTGCACATGATGGCATCGTGATTAAGATCGAGGTGCAGACCAACGATGAGGGCTCA
GAAGGTCTGGAGACACCAGAGCCGCTGATGGGACAAGTGGAGGAACACGGCTTTCAGGACTCAG
AGCTGGGTGACCCCTGTGGAGAGCAGCCAGACCTGGACATGCAGGACCAAGAGAACGTGCTAGA
GGAGTCCACTGAAGGCTCCAGTGAGTTCAGTGAGCTCAAGCAGATGCTGGTGCAGCAGAGAAAC
TGCACGGAGGGGATCGTGATAAAGACAGAGGAGCAGGAAGAGGATGAGGAAGAGGAAGAGGAGG
ATGAGCTGCCACAGCACTTGCAATCCCTTGGGCAGCTGTCTGGGAGGTACGAGGCCAGTATGTA
CCAGACTCCCCTCCCTGGGGAGATGTCCCCCGAGGGCGAGGAAAGCCCCCCACCCCTGCAATTA
GGCAACCCAGCAGTGAAGAGGCTGGCACCCAGCATTCATGGGCATACACATGGGCATGGGCATG
GTGAGCGGCATCTGGGTGAGAACCGTGGGAACTCCAGCCAGCAGCAGCGAAACCGGCGTGGTGA
GCGGCCCTTCACTTGCATGGAGTGTGGCAAAAGCTTTCGGCTGAAGATTAACCTCATCATCCAC
CAGCGTAACCACATTAAGGAGGGGCCCTATGAGTGTGCCGAGTGTGAGATCAGCTTCCGCCACA
AGCAGCAACTCACGCTGCACCAGCGCATCCACCGAGTACGCAGCGGCTACGCCTCCCCTGAGCG
CGGATCAGCCTTCAATCCCAAGCACTCGCTCAAGCCGCGTCCCAAATCGCCTAGCTCAGGCAGT
GGTGGAGGCCCCAAGCCCTACAAGTGCCCAGAGTGTGACAGCAGCTTCAGCCACAAGTCAAGCC
TGACCAAGCATCAGATCACACACACGGGCGAGAGGCCCTACACATGCCCAGAATGCAAGAAGAG
CTTCCGTTTGCATATCAGCCTGGTGATCCACCAGCGCGTGCATGCTGGCAAGCACGAAGTCTCC
TTCATTTGCAGCCTGTGCGGCAAGAGCTTCAGCCGCCCGTCGCATCTGCTGCGCCACCAGCGGA
CTCATACCGGTGAACGGCCCTTCAAGTGCCCGGAGTGTGAGAAGAGCTTCAGTGAGAAATCTAA
GCTCACTAACCACTGCCGCGTGCACTCGCGCGAACGGCCGCACGCCTGCCCTGAGTGCGGCAAG
AGCTTCATCCGCAAGCACCACCTGCTGGAGCACCGGCGCATCCATACGGGTGAGCGGCCCTACC
ACTGCGCTGAGTGTGGCAAGCGCTTCACACAGAAGCACCACCTGCTGGAGCACCAGCGAGCGCA
CACGGGCGAGCGGCCCTACCCCTGCACGCACTGTGCTAAGTGCTTCCGCTACAAACAGTCCCTC
AAGTACCACCTGCGGACCCACACGGGCGAGTGAGCATGCGCCCCGCCCCTGCCCCGGCCAGATG
CGCAGCCAGGTGCAAGGGTCTAAGGCCCCTGGGACAGGTACCTCGGCTGCCCCCAGACTGAGCT
CAGTGGGCGGGAGCGGGGCGCCCCAAGCCCTTCTGCTGTGAACCCTTCTCCTCTCCCGTCCCTT
CTCCCCAGGACGGGGTAGTGAAACCAGGTCGCTTGTTGCCTGCTTCCCCAGGGCCCCTGGGGGG
AGCGCTTGGGCCTGGGGAACCCCTTCAGGCTGTTAATTTCCTTGACAATAAAATGGATGAAAAC
AATCTGCACGGGGGCAGTGATTTGGCTGCCAGCCACTCGCAGGCGCGATGCAGGGCCATTTAGT
CGGGAATAGAACTTTCTAATTACCTTTTGGATACTGTGGTTCTATTTGATAATAATAGAGTAAT
TTTTAAAAGACGAGTGTTTCCTGTT

hide sequence

RefSeq Acc Id:

XM_063286611 ⟹ XP_063142681

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	78,347,315 - 78,372,543 (-)	NCBI

RefSeq Acc Id:

XM_063286612 ⟹ XP_063142682

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	78,347,315 - 78,373,176 (-)	NCBI

RefSeq Acc Id:

XM_063286613 ⟹ XP_063142683

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	78,347,315 - 78,377,720 (-)	NCBI

RefSeq Acc Id:

XM_063286614 ⟹ XP_063142684

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	78,347,315 - 78,362,993 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102818	(Get FASTA)	NCBI Sequence Viewer
	XP_063142681	(Get FASTA)	NCBI Sequence Viewer
	XP_063142682	(Get FASTA)	NCBI Sequence Viewer
	XP_063142683	(Get FASTA)	NCBI Sequence Viewer
	XP_063142684	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL88280	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034825
	ENSRNOP00000034825.5
	ENSRNOP00000079994
	ENSRNOP00000079994.2

RefSeq Acc Id:

NP_001102818 ⟸ NM_001109348

- UniProtKB:

A0A8I5ZP65 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEDDRSSPLSFSRIPHEESVHQAPARLPRETVFSSCILPPKEISPLSPTAPQQAALPQTDSPPK
QETSGQMSHVLQKGPSLLCPATSEQDTPHQVSLASQEETHSPPSAAGQGIPFLSHSTHHQDAPL
HSPEAPEKDSLTLSPTVPETDMDPLLQSPTLQKDTPFHTSSAAQKEQPLPTAEITRLAVWAAVQ
AVERKLEAQAMRLLTLESRTGTNEKKIADCERTAVEFANHLESKWVVLGTLLQEYGLLQRRLEN
MENLLKNRNFWILRLPPGSNGEVPKVPVTFDDVAVHFSEQEWGNLSEWQKELYKNVMRGNYESL
VSMDYAISKPDLMSQMERGERPAMQEQEDSEEGETPTDPSAAHDGIVIKIEVQTNDEGSEGLET
PEPLMGQVEEHGFQDSELGDPCGEQPDLDMQDQENVLEESTEGSSEFSELKQMLVQQRNCTEGI
VIKTEEQEEDEEEEEEDELPQHLQSLGQLSGRYEASMYQTPLPGEMSPEGEESPPPLQLGNPAV
KRLAPSIHGHTHGHGHGERHLGENRGNSSQQQRNRRGERPFTCMECGKSFRLKINLIIHQRNHI
KEGPYECAECEISFRHKQQLTLHQRIHRVRSGYASPERGSAFNPKHSLKPRPKSPSSGSGGGPK
PYKCPECDSSFSHKSSLTKHQITHTGERPYTCPECKKSFRLHISLVIHQRVHAGKHEVSFICSL
CGKSFSRPSHLLRHQRTHTGERPFKCPECEKSFSEKSKLTNHCRVHSRERPHACPECGKSFIRK
HHLLEHRRIHTGERPYHCAECGKRFTQKHHLLEHQRAHTGERPYPCTHCAKCFRYKQSLKYHLR
THTGE

hide sequence

Ensembl Acc Id:

ENSRNOP00000034825 ⟸ ENSRNOT00000038517

Ensembl Acc Id:

ENSRNOP00000079994 ⟸ ENSRNOT00000113218

RefSeq Acc Id:	XP_063142683 ⟸ XM_063286613
- Peptide Label:	isoform X2
- UniProtKB:	A6K0D8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142682 ⟸ XM_063286612
- Peptide Label:	isoform X2
- UniProtKB:	A6K0D8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142681 ⟸ XM_063286611
- Peptide Label:	isoform X1
- UniProtKB:	F1LV17 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142684 ⟸ XM_063286614
- Peptide Label:	isoform X3

Protein Domains

C2H2-type KRAB KRAB-related

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LV17-F1-model_v2	AlphaFold	F1LV17	1-837	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566056	AgrOrtholog
BioCyc Gene	G2FUF-45000	BioCyc
Ensembl Genes	ENSRNOG00000033639	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038517	ENTREZGENE
	ENSRNOT00000038517.5	UniProtKB/TrEMBL
	ENSRNOT00000113218	ENTREZGENE
	ENSRNOT00000113218.2	UniProtKB/TrEMBL
Gene3D-CATH	6.10.140.140	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	GLI_C2H2-zinc-finger	UniProtKB/TrEMBL
	KRAB_dom_sf	UniProtKB/TrEMBL
	Krueppel-associated_box	UniProtKB/TrEMBL
	Krueppel-associated_box-rel	UniProtKB/TrEMBL
	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
KEGG Report	rno:502764	UniProtKB/TrEMBL
NCBI Gene	502764	ENTREZGENE
PANTHER	C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN ZIC AND GLI	UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PhenoGen	Zfp777	PhenoGen
PROSITE	KRAB	UniProtKB/TrEMBL
	KRAB_RELATED	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000033639	RatGTEx
SMART	KRAB	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	Krueppel-associated_box	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A0A8I5ZP65	ENTREZGENE, UniProtKB/TrEMBL
	A6K0D8	ENTREZGENE, UniProtKB/TrEMBL
	F1LV17	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-07-19	Zfp777	zinc finger protein 777	Znf777	zinc finger protein 777	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Znf777	zinc finger protein 777	Zfp777	zinc finger protein 777	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Zfp777	zinc finger protein 777	RGD1566056_predicted	similar to KIAA1285 protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1566056_predicted	similar to KIAA1285 protein (predicted)	LOC502764	similar to KIAA1285 protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC502764	similar to KIAA1285 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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