Flrt3 (fibronectin leucine rich transmembrane protein 3) - Rat Genome Database

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Gene: Flrt3 (fibronectin leucine rich transmembrane protein 3) Rattus norvegicus
Analyze
Symbol: Flrt3
Name: fibronectin leucine rich transmembrane protein 3
RGD ID: 1566005
Description: Predicted to enable chemorepellent activity; fibroblast growth factor receptor binding activity; and protein homodimerization activity. Involved in neuron projection extension and response to axon injury. Acts upstream of or within axon guidance. Located in axon terminus and synaptic membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 21 with or without anosmia. Orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: fibronectin-like domain-containing leucine-rich transmembrane protein 3; leucine-rich repeat transmembrane protein FLRT3; LOC366205; RGD1566005; similar to fibronectin leucine rich transmembrane protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,448,115 - 148,461,458 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3148,439,354 - 148,461,650 (-)EnsemblGRCr8
mRatBN7.23127,994,491 - 128,008,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,994,226 - 128,007,841 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3131,850,711 - 131,863,013 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,434,799 - 140,447,106 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03138,137,914 - 138,150,220 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,684,446 - 134,696,586 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,683,065 - 134,696,654 (-)Ensemblrn6Rnor6.0
Rnor_5.03141,134,890 - 141,147,030 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43128,922,726 - 128,934,866 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3126,621,420 - 126,633,560 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitriptyline  (EXP)
amitrole  (EXP)
amphotericin B  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arotinoid acid  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cocaine  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fluorescein 5-isothiocyanate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gallic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycine betaine  (EXP)
hydrogen peroxide  (ISO)
iron dichloride  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
menadione  (ISO)
methimazole  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mitoxantrone  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
XAV939  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. O'Sullivan ML, etal., Neuron. 2012 Mar 8;73(5):903-10. doi: 10.1016/j.neuron.2012.01.018.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. FLRT3 is expressed in sensory neurons after peripheral nerve injury and regulates neurite outgrowth. Robinson M, etal., Mol Cell Neurosci. 2004 Oct;27(2):202-14.
7. FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. Yamagishi S, etal., EMBO J. 2011 Jun 14;30(14):2920-33. doi: 10.1038/emboj.2011.189.
Additional References at PubMed
PMID:12477932   PMID:14706654   PMID:16872596   PMID:18448090   PMID:24560577   PMID:24613359   PMID:26235030   PMID:31346030  


Genomics

Comparative Map Data
Flrt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,448,115 - 148,461,458 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3148,439,354 - 148,461,650 (-)EnsemblGRCr8
mRatBN7.23127,994,491 - 128,008,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,994,226 - 128,007,841 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3131,850,711 - 131,863,013 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,434,799 - 140,447,106 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03138,137,914 - 138,150,220 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,684,446 - 134,696,586 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,683,065 - 134,696,654 (-)Ensemblrn6Rnor6.0
Rnor_5.03141,134,890 - 141,147,030 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43128,922,726 - 128,934,866 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3126,621,420 - 126,633,560 (-)NCBICelera
Cytogenetic Map3q41NCBI
FLRT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382014,322,985 - 14,337,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2014,322,985 - 14,337,631 (-)Ensemblhg38GRCh38
GRCh372014,303,631 - 14,318,258 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362014,252,643 - 14,266,270 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342014,252,642 - 14,266,270NCBI
Celera2014,379,950 - 14,393,623 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2014,264,895 - 14,278,567 (-)NCBIHuRef
CHM1_12014,304,603 - 14,318,275 (-)NCBICHM1_1
T2T-CHM13v2.02014,372,130 - 14,386,755 (-)NCBIT2T-CHM13v2.0
Flrt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392140,500,118 - 140,513,396 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2140,492,834 - 140,513,389 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382140,658,198 - 140,671,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,650,914 - 140,671,469 (-)Ensemblmm10GRCm38
MGSCv372140,483,934 - 140,497,212 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362140,349,640 - 140,362,910 (-)NCBIMGSCv36mm8
Celera2141,850,226 - 141,863,510 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Flrt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,669,749 - 23,683,235 (-)Ensembl
ChiLan1.0NW_00495541523,669,749 - 23,683,235 (-)NCBIChiLan1.0ChiLan1.0
FLRT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22115,223,313 - 15,238,927 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12015,217,075 - 15,235,719 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02014,294,903 - 14,310,584 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12014,279,967 - 14,293,632 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2014,281,522 - 14,283,471 (-)EnsemblpanPan2panpan1.1
FLRT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,354,151 - 8,367,601 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,364,115 - 8,366,064 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha248,165,848 - 8,179,356 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0248,763,355 - 8,776,862 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl248,763,393 - 8,776,857 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,356,554 - 8,370,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,455,701 - 8,469,207 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0248,810,713 - 8,824,225 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Flrt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364855,532,853 - 5,546,392 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364855,532,554 - 5,547,430 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLRT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,940,492 - 22,954,424 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11722,940,491 - 22,955,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,670,538 - 25,684,556 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FLRT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1243,252,181 - 43,267,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl243,255,347 - 43,257,296 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660543,530,057 - 3,543,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flrt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474115,343,653 - 15,355,727 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474115,343,304 - 15,355,742 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Flrt3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15119,923,154 - 119,936,491 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Flrt3
130 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:65
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000006454
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 36 59 6 297 136 11 142 78 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006454   ⟹   ENSRNOP00000006454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,439,354 - 148,461,573 (-)Ensembl
mRatBN7.2 Ensembl3127,994,226 - 128,007,841 (-)Ensembl
Rnor_6.0 Ensembl3134,683,065 - 134,696,654 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115709   ⟹   ENSRNOP00000089101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,446,399 - 148,461,650 (-)Ensembl
mRatBN7.2 Ensembl3127,994,467 - 128,000,563 (-)Ensembl
RefSeq Acc Id: NM_001126291   ⟹   NP_001119763
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,449,265 - 148,461,405 (-)NCBI
mRatBN7.23127,995,633 - 128,007,773 (-)NCBI
Rnor_6.03134,684,446 - 134,696,586 (-)NCBI
Rnor_5.03141,134,890 - 141,147,030 (-)NCBI
RGSC_v3.43128,922,726 - 128,934,866 (-)RGD
Celera3126,621,420 - 126,633,560 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105601   ⟹   XP_038961529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,448,115 - 148,461,458 (-)NCBI
mRatBN7.23127,994,491 - 128,008,137 (-)NCBI
RefSeq Acc Id: NP_001119763   ⟸   NM_001126291
- Peptide Label: precursor
- UniProtKB: B1H234 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006454   ⟸   ENSRNOT00000006454
RefSeq Acc Id: XP_038961529   ⟸   XM_039105601
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHD5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089101   ⟸   ENSRNOT00000115709
Protein Domains
Fibronectin type-III   LRRCT   LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1H234-F1-model_v2 AlphaFold B1H234 1-649 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692475
Promoter ID:EPDNEW_R2998
Type:initiation region
Name:Flrt3_1
Description:fibronectin leucine rich transmembrane protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03134,696,624 - 134,696,684EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566005 AgrOrtholog
BioCyc Gene G2FUF-47653 BioCyc
Ensembl Genes ENSRNOG00000004874 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006454.7 UniProtKB/Swiss-Prot
  ENSRNOT00000115709 ENTREZGENE
  ENSRNOT00000115709.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:8361648 IMAGE-MGC_LOAD
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
  SLRP UniProtKB/Swiss-Prot
KEGG Report rno:366205 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187569 IMAGE-MGC_LOAD
NCBI Gene 366205 ENTREZGENE
PANTHER AGAP008170-PA UniProtKB/Swiss-Prot
  LRRNT DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam LRR_8 UniProtKB/Swiss-Prot
PhenoGen Flrt3 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  LRR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004874 RatGTEx
SMART LRR_TYP UniProtKB/Swiss-Prot
  LRRCT UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot
UniProt A0A0H2UHD5 ENTREZGENE, UniProtKB/TrEMBL
  B1H234 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Flrt3  fibronectin leucine rich transmembrane protein 3   Flrt3_predicted  fibronectin leucine rich transmembrane protein 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Flrt3_predicted  fibronectin leucine rich transmembrane protein 3 (predicted)  RGD1566005_predicted  similar to fibronectin leucine rich transmembrane protein 3 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1566005_predicted  similar to fibronectin leucine rich transmembrane protein 3 (predicted)  LOC366205  similar to fibronectin leucine rich transmembrane protein 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC366205  similar to fibronectin leucine rich transmembrane protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL