Satl1 (spermidine/spermine N1-acetyl transferase-like 1) - Rat Genome Database

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Gene: Satl1 (spermidine/spermine N1-acetyl transferase-like 1) Rattus norvegicus
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Symbol: Satl1
Name: spermidine/spermine N1-acetyl transferase-like 1
RGD ID: 1565932
Description: Predicted to enable diamine N-acetyltransferase activity and spermidine binding activity. Predicted to be involved in spermidine acetylation. Orthologous to human SATL1 (spermidine/spermine N1-acetyl transferase like 1); INTERACTS WITH bisphenol A; trichloroethene; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC302325; RGD1565932; similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1); similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) (Putrescine acetyltransferase) (Polyamine N-acetyltransferase 1); spermidine/spermine N(1)-acetyltransferase-like protein 1
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X81,645,584 - 81,661,393 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX81,645,454 - 81,661,246 (-)EnsemblGRCr8
mRatBN7.2X77,453,357 - 77,469,100 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX77,453,357 - 77,469,158 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX79,110,705 - 79,126,134 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X82,541,648 - 82,557,097 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X80,129,815 - 80,145,290 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X83,772,526 - 83,788,556 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX83,772,495 - 83,788,325 (-)Ensemblrn6Rnor6.0
Rnor_5.0X83,722,050 - 83,737,843 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X100,989,274 - 101,004,732 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX78,752,966 - 78,768,399 (-)NCBICelera
Cytogenetic MapXq31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Satl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X81,645,584 - 81,661,393 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX81,645,454 - 81,661,246 (-)EnsemblGRCr8
mRatBN7.2X77,453,357 - 77,469,100 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX77,453,357 - 77,469,158 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX79,110,705 - 79,126,134 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X82,541,648 - 82,557,097 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X80,129,815 - 80,145,290 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X83,772,526 - 83,788,556 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX83,772,495 - 83,788,325 (-)Ensemblrn6Rnor6.0
Rnor_5.0X83,722,050 - 83,737,843 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X100,989,274 - 101,004,732 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX78,752,966 - 78,768,399 (-)NCBICelera
Cytogenetic MapXq31NCBI
SATL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X85,092,284 - 85,243,779 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX85,092,284 - 85,243,911 (-)Ensemblhg38GRCh38
GRCh37X84,347,290 - 84,498,785 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X84,233,956 - 84,250,102 (-)NCBIBuild 36Build 36hg18NCBI36
CeleraX84,586,693 - 84,603,357 (-)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX77,920,841 - 77,937,503 (-)NCBIHuRef
CHM1_1X84,241,011 - 84,257,690 (-)NCBICHM1_1
T2T-CHM13v2.0X83,521,243 - 83,672,628 (-)NCBIT2T-CHM13v2.0
Satl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X111,294,002 - 111,316,476 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX111,294,000 - 111,316,476 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X112,384,305 - 112,406,779 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX112,384,303 - 112,406,779 (-)Ensemblmm10GRCm38
MGSCv37X109,497,914 - 109,520,388 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X108,501,249 - 108,523,700 (-)NCBIMGSCv36mm8
CeleraX99,023,402 - 99,045,933 (-)NCBICelera
Cytogenetic MapXE1NCBI
cM MapX48.76NCBI
SATL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X84,571,201 - 84,721,438 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X84,572,478 - 84,725,045 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X74,163,746 - 74,314,004 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X84,273,288 - 84,290,102 (-)NCBIPanPan1.1PanPan1.1panPan2
SATL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X65,955,694 - 65,984,081 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX65,955,743 - 65,983,284 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX56,712,132 - 56,740,615 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X67,284,657 - 67,313,140 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX67,284,706 - 67,312,351 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X64,934,304 - 64,962,785 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X66,566,682 - 66,595,354 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X66,163,060 - 66,191,543 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Satl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X59,540,126 - 59,554,699 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365475,858,120 - 5,874,745 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SATL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X68,356,415 - 68,383,729 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X78,156,763 - 78,182,928 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SATL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X73,930,049 - 73,956,524 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX73,930,156 - 73,955,780 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660676,884,051 - 6,910,526 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Satl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X62,204,183 - 62,217,199 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Satl1
87 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:21
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000037149
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 11 21 51 47 44 15 32 15 6 132 76 38 25 48 29 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000037149   ⟹   ENSRNOP00000034830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX81,645,588 - 81,661,246 (-)Ensembl
mRatBN7.2 EnsemblX77,453,357 - 77,469,158 (-)Ensembl
Rnor_6.0 EnsemblX83,772,495 - 83,788,325 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106441   ⟹   ENSRNOP00000082605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX81,645,588 - 81,661,246 (-)Ensembl
mRatBN7.2 EnsemblX77,453,357 - 77,469,158 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144938   ⟹   ENSRNOP00000100069
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX81,645,454 - 81,661,246 (-)Ensembl
RefSeq Acc Id: NM_001163543   ⟹   NP_001157015
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,645,588 - 81,661,047 (-)NCBI
mRatBN7.2X77,453,357 - 77,468,816 (-)NCBI
Rnor_6.0X83,772,526 - 83,787,983 (-)NCBI
Rnor_5.0X83,722,050 - 83,737,843 (-)NCBI
RGSC_v3.4X100,989,274 - 101,004,732 (-)RGD
CeleraX78,752,966 - 78,768,399 (-)RGD
Sequence:
RefSeq Acc Id: XM_039099582   ⟹   XP_038955510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,645,584 - 81,661,389 (-)NCBI
mRatBN7.2X77,453,487 - 77,467,117 (-)NCBI
RefSeq Acc Id: XM_063279889   ⟹   XP_063135959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,645,584 - 81,661,389 (-)NCBI
RefSeq Acc Id: XM_063279890   ⟹   XP_063135960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,645,584 - 81,661,393 (-)NCBI
RefSeq Acc Id: NP_001157015   ⟸   NM_001163543
- UniProtKB: D3ZA19 (UniProtKB/TrEMBL),   A6IV98 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000034830   ⟸   ENSRNOT00000037149
RefSeq Acc Id: XP_038955510   ⟸   XM_039099582
- Peptide Label: isoform X1
- UniProtKB: A6IV98 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082605   ⟸   ENSRNOT00000106441
RefSeq Acc Id: XP_063135960   ⟸   XM_063279890
- Peptide Label: isoform X3
- UniProtKB: A6IV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135959   ⟸   XM_063279889
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZV75 (UniProtKB/TrEMBL),   A6IV98 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100069   ⟸   ENSRNOT00000144938
Protein Domains
N-acetyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZA19-F1-model_v2 AlphaFold D3ZA19 1-758 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565932 AgrOrtholog
BioCyc Gene G2FUF-1834 BioCyc
Ensembl Genes ENSRNOG00000022476 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037149 ENTREZGENE
  ENSRNOT00000037149.7 UniProtKB/TrEMBL
  ENSRNOT00000106441 ENTREZGENE
  ENSRNOT00000106441.2 UniProtKB/TrEMBL
  ENSRNOT00000144938 ENTREZGENE
  ENSRNOT00000144938.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.30 UniProtKB/TrEMBL
InterPro AcTrfase_GCN5-related UniProtKB/TrEMBL
  Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  Diverse_Substrate_AcTransf UniProtKB/TrEMBL
KEGG Report rno:302325 UniProtKB/TrEMBL
NCBI Gene 302325 ENTREZGENE
PANTHER DIAMINE N-ACETYLTRANSFERASE UniProtKB/TrEMBL
  SPERMIDINE/SPERMINE N(1)-ACETYLTRANSFERASE-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam Acetyltransf_1 UniProtKB/TrEMBL
PhenoGen Satl1 PhenoGen
PROSITE GNAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022476 RatGTEx
Superfamily-SCOP Acyl_CoA_acyltransferase UniProtKB/TrEMBL
UniProt A0A8I5ZV75 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L7K0_RAT UniProtKB/TrEMBL
  A6IV98 ENTREZGENE, UniProtKB/TrEMBL
  D3ZA19 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Satl1  spermidine/spermine N1-acetyl transferase-like 1  RGD1565932_predicted  similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-10 RGD1565932_predicted  similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1) (predicted)    similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) (Putrescine acetyltransferase) (Polyamine N-acetyltransferase 1) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1565932_predicted  similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) (Putrescine acetyltransferase) (Polyamine N-acetyltransferase 1) (predicted)  LOC302325  similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) (Putrescine acetyltransferase) (Polyamine N-acetyltransferase 1)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302325  similar to Diamine acetyltransferase 1 (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) (Putrescine acetyltransferase) (Polyamine N-acetyltransferase 1)      Symbol and Name status set to provisional 70820 PROVISIONAL