Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fgd6 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FGD6 mRNA | CTD | PMID:22079256 | Fgd6 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Fgd6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of FGD6 mRNA | CTD | PMID:36331819 | Fgd6 | Rat | 1,1-dichloroethene | increases expression | ISO | Fgd6 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of FGD6 mRNA | CTD | PMID:26682919 | Fgd6 | Rat | 17beta-estradiol | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [ESR2 protein affects the expression of FGD6 mRNA] | CTD | PMID:20404318 | Fgd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGD6 mRNA | CTD | PMID:15328365 | Fgd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGD6 mRNA | CTD | PMID:32109520 | Fgd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGD6 mRNA | CTD | PMID:20106945|PMID:21632981 | Fgd6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fgd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGD6 mRNA | CTD | PMID:21570461 | Fgd6 | Rat | 2-hydroxypropanoic acid | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of FGD6 mRNA | CTD | PMID:30851411 | Fgd6 | Rat | 2-palmitoylglycerol | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of FGD6 mRNA | CTD | PMID:37199045 | Fgd6 | Rat | 5-fluorouracil | affects response to substance | ISO | FGD6 (Homo sapiens) | 6480464 | FGD6 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | Fgd6 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FGD6 mRNA | CTD | PMID:31881176 | Fgd6 | Rat | aflatoxin B1 | increases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of FGD6 mRNA | CTD | PMID:19770486 | Fgd6 | Rat | aflatoxin B1 | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of FGD6 mRNA | CTD | PMID:22100608|PMID:27153756 | Fgd6 | Rat | aflatoxin B1 | increases methylation | ISO | FGD6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of FGD6 exon; Aflatoxin B1 results in increased methylation more ... | CTD | PMID:27153756|PMID:30157460 | Fgd6 | Rat | all-trans-retinoic acid | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of FGD6 mRNA | CTD | PMID:23724009|PMID:23830798 | Fgd6 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of FGD6 mRNA | CTD | PMID:35163327 | Fgd6 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of FGD6 gene | CTD | PMID:28931070 | Fgd6 | Rat | avobenzone | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | avobenzone results in increased expression of FGD6 mRNA | CTD | PMID:31016361 | Fgd6 | Rat | benzo[a]pyrene | increases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of FGD6 mRNA | CTD | PMID:22228805 | Fgd6 | Rat | benzo[a]pyrene | affects methylation | ISO | FGD6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FGD6 3' UTR | CTD | PMID:27901495 | Fgd6 | Rat | benzo[a]pyrene | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of FGD6 mRNA | CTD | PMID:20064835|PMID:21632981 | Fgd6 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of FGD6 mRNA | CTD | PMID:25181051 | Fgd6 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FGD6 mRNA | CTD | PMID:34947998 | Fgd6 | Rat | Butylbenzyl phthalate | decreases methylation | ISO | Fgd6 (Mus musculus) | 6480464 | butylbenzyl phthalate results in decreased methylation of FGD6 intron | CTD | PMID:28392331 | Fgd6 | Rat | cadmium dichloride | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of FGD6 mRNA | CTD | PMID:38568856 | Fgd6 | Rat | caffeine | decreases phosphorylation | ISO | FGD6 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of FGD6 protein | CTD | PMID:35688186 | Fgd6 | Rat | chlorpyrifos | decreases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of FGD6 mRNA | CTD | PMID:37019170 | Fgd6 | Rat | chromium(6+) | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | chromium hexavalent ion results in decreased expression of FGD6 mRNA | CTD | PMID:30690063 | Fgd6 | Rat | clofibrate | decreases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of FGD6 mRNA | CTD | PMID:23811191 | Fgd6 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of FGD6 mRNA | CTD | PMID:26033743 | Fgd6 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of FGD6 mRNA | CTD | PMID:26033743 | Fgd6 | Rat | copper(II) sulfate | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of FGD6 mRNA | CTD | PMID:19549813 | Fgd6 | Rat | daidzein | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with more ... | CTD | PMID:27424125 | Fgd6 | Rat | daidzein 7-O-beta-D-glucoside | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with more ... | CTD | PMID:27424125 | Fgd6 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of FGD6 mRNA | CTD | PMID:23914054 | Fgd6 | Rat | Dibutyl phosphate | affects expression | ISO | FGD6 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of FGD6 mRNA | CTD | PMID:37042841 | Fgd6 | Rat | dimethylarsinous acid | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | dimethylarsinous acid results in increased expression of FGD6 mRNA | CTD | PMID:23487506 | Fgd6 | Rat | dorsomorphin | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Fgd6 | Rat | doxorubicin | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of FGD6 mRNA | CTD | PMID:29803840 | Fgd6 | Rat | ethanol | increases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Ethanol results in increased expression of FGD6 mRNA | CTD | PMID:30319688 | Fgd6 | Rat | fenthion | decreases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Fenthion results in decreased expression of FGD6 mRNA | CTD | PMID:34813904 | Fgd6 | Rat | fluoranthene | multiple interactions | ISO | Fgd6 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of FGD6 mRNA | CTD | PMID:28329830 | Fgd6 | Rat | FR900359 | decreases phosphorylation | ISO | FGD6 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FGD6 protein | CTD | PMID:37730182 | Fgd6 | Rat | furan | decreases methylation | EXP | | 6480464 | furan results in decreased methylation of FGD6 gene | CTD | PMID:27387713 | Fgd6 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of FGD6 mRNA | CTD | PMID:27387713 | Fgd6 | Rat | genistein | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with more ... | CTD | PMID:27424125 | Fgd6 | Rat | genistein 7-O-beta-D-glucoside | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with more ... | CTD | PMID:27424125 | Fgd6 | Rat | glycitein | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with more ... | CTD | PMID:27424125 | Fgd6 | Rat | glycitin | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with more ... | CTD | PMID:27424125 | Fgd6 | Rat | inulin | multiple interactions | ISO | Fgd6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of FGD6 mRNA | CTD | PMID:36331819 | Fgd6 | Rat | lead(0) | affects expression | ISO | FGD6 (Homo sapiens) | 6480464 | Lead affects the expression of FGD6 mRNA | CTD | PMID:28903495 | Fgd6 | Rat | melphalan | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Melphalan results in decreased expression of FGD6 mRNA | CTD | PMID:22363485 | Fgd6 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of FGD6 gene | CTD | PMID:35440735 | Fgd6 | Rat | okadaic acid | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of FGD6 mRNA | CTD | PMID:38832940 | Fgd6 | Rat | paracetamol | affects expression | ISO | Fgd6 (Mus musculus) | 6480464 | Acetaminophen affects the expression of FGD6 mRNA | CTD | PMID:17562736 | Fgd6 | Rat | paracetamol | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of FGD6 mRNA | CTD | PMID:26690555 | Fgd6 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Fgd6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of FGD6 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Fgd6 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of FGD6 mRNA | CTD | PMID:35163327 | Fgd6 | Rat | phenylmercury acetate | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of FGD6 mRNA | CTD | PMID:26272509 | Fgd6 | Rat | phenylmercury acetate | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Fgd6 | Rat | potassium chromate | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FGD6 mRNA | CTD | PMID:22079256 | Fgd6 | Rat | potassium chromate | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FGD6 mRNA | CTD | PMID:22079256|PMID:22714537 | Fgd6 | Rat | quercetin | affects expression | ISO | FGD6 (Homo sapiens) | 6480464 | Quercetin affects the expression of FGD6 mRNA | CTD | PMID:21632981 | Fgd6 | Rat | rac-lactic acid | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of FGD6 mRNA | CTD | PMID:30851411 | Fgd6 | Rat | raloxifene | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA | CTD | PMID:19059307 | Fgd6 | Rat | SB 431542 | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Fgd6 | Rat | silicon dioxide | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of FGD6 mRNA | CTD | PMID:25351596 | Fgd6 | Rat | sulforaphane | decreases expression | ISO | Fgd6 (Mus musculus) | 6480464 | sulforaphane results in decreased expression of FGD6 mRNA | CTD | PMID:30529165 | Fgd6 | Rat | sunitinib | decreases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of FGD6 mRNA | CTD | PMID:31533062 | Fgd6 | Rat | tamoxifen | multiple interactions | ISO | FGD6 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA | CTD | PMID:19059307 | Fgd6 | Rat | tetrachloromethane | increases expression | ISO | Fgd6 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of FGD6 mRNA | CTD | PMID:17484886|PMID:31919559 | Fgd6 | Rat | tetraphene | decreases expression | ISO | Fgd6 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of FGD6 mRNA | CTD | PMID:26377693 | Fgd6 | Rat | thimerosal | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Thimerosal results in increased expression of FGD6 mRNA | CTD | PMID:27188386 | Fgd6 | Rat | titanium dioxide | decreases methylation | ISO | Fgd6 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FGD6 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Fgd6 | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of FGD6 gene | CTD | PMID:27618143 | Fgd6 | Rat | trichostatin A | affects expression | ISO | FGD6 (Homo sapiens) | 6480464 | trichostatin A affects the expression of FGD6 mRNA | CTD | PMID:28542535 | Fgd6 | Rat | troglitazone | decreases expression | ISO | Fgd6 (Mus musculus) | 6480464 | troglitazone results in decreased expression of FGD6 mRNA | CTD | PMID:28973697 | Fgd6 | Rat | urethane | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | Urethane results in increased expression of FGD6 mRNA | CTD | PMID:28818685 | Fgd6 | Rat | vanadyl sulfate | increases expression | ISO | FGD6 (Homo sapiens) | 6480464 | vanadyl sulfate results in increased expression of FGD6 mRNA | CTD | PMID:16330358 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















