Fgd6 (FYVE, RhoGEF and PH domain containing 6) - Rat Genome Database

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Pathways
Gene: Fgd6 (FYVE, RhoGEF and PH domain containing 6) Rattus norvegicus
Analyze
Symbol: Fgd6
Name: FYVE, RhoGEF and PH domain containing 6
RGD ID: 1565609
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Orthologous to human FGD6 (FYVE, RhoGEF and PH domain containing 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FYVE, RhoGEF and PH domain-containing protein 6; LOC500824; RGD1565609; similar to FYVE, RhoGEF and PH domain containing 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,484,600 - 30,599,898 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl730,484,600 - 30,595,806 (+)EnsemblGRCr8
mRatBN7.2728,597,609 - 28,712,908 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,597,609 - 28,712,456 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx730,595,441 - 30,706,847 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,757,688 - 32,869,096 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0732,528,179 - 32,639,612 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,951,878 - 35,063,006 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,952,011 - 35,063,929 (+)Ensemblrn6Rnor6.0
Rnor_5.0735,009,998 - 35,135,105 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4731,160,021 - 31,286,379 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera725,690,957 - 25,801,895 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
atrazine  (EXP)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
decabromodiphenyl ether  (EXP)
Dibutyl phosphate  (ISO)
dimethylarsinous acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenthion  (ISO)
fluoranthene  (ISO)
FR900359  (ISO)
furan  (EXP)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glycitein  (ISO)
glycitin  (ISO)
inulin  (ISO)
lead(0)  (ISO)
melphalan  (ISO)
methoxychlor  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
vanadyl sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytoskeleton  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Fgd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,484,600 - 30,599,898 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl730,484,600 - 30,595,806 (+)EnsemblGRCr8
mRatBN7.2728,597,609 - 28,712,908 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,597,609 - 28,712,456 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx730,595,441 - 30,706,847 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,757,688 - 32,869,096 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0732,528,179 - 32,639,612 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,951,878 - 35,063,006 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,952,011 - 35,063,929 (+)Ensemblrn6Rnor6.0
Rnor_5.0735,009,998 - 35,135,105 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4731,160,021 - 31,286,379 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera725,690,957 - 25,801,895 (+)NCBICelera
Cytogenetic Map7q13NCBI
FGD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381295,076,749 - 95,217,467 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1295,076,749 - 95,217,482 (-)Ensemblhg38GRCh38
GRCh371295,470,525 - 95,611,243 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361293,994,656 - 94,135,371 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1295,141,807 - 95,282,177 (-)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1292,537,521 - 92,679,789 (-)NCBIHuRef
CHM1_11295,435,464 - 95,576,763 (-)NCBICHM1_1
T2T-CHM13v2.01295,057,451 - 95,198,262 (-)NCBIT2T-CHM13v2.0
Fgd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391093,871,862 - 93,981,201 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1093,871,863 - 93,981,201 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381094,035,979 - 94,145,339 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1094,036,001 - 94,145,339 (+)Ensemblmm10GRCm38
MGSCv371093,498,746 - 93,608,084 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361093,465,800 - 93,571,803 (+)NCBIMGSCv36mm8
Celera1096,010,198 - 96,120,691 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.76NCBI
Fgd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540531,698,963 - 31,801,967 (-)Ensembl
ChiLan1.0NW_00495540531,700,706 - 31,801,992 (-)NCBIChiLan1.0ChiLan1.0
FGD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210103,150,485 - 103,290,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112103,146,876 - 103,286,877 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01292,669,106 - 92,809,002 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11296,065,059 - 96,203,335 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1296,065,059 - 96,203,262 (-)EnsemblpanPan2panpan1.1
FGD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11535,050,993 - 35,162,421 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1535,055,469 - 35,162,224 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1535,437,678 - 35,549,099 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01535,715,346 - 35,826,806 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1535,719,824 - 35,826,617 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11534,988,648 - 35,100,047 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01535,083,820 - 35,194,921 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01535,346,448 - 35,457,712 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fgd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494524,796,915 - 24,909,957 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650711,326,465 - 11,435,219 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650711,325,599 - 11,438,561 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl588,104,899 - 88,221,828 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1588,087,032 - 88,229,807 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2592,455,962 - 92,478,709 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11190,489,879 - 90,622,251 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1190,490,912 - 90,622,295 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037154,545,328 - 154,681,480 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475011,868,463 - 11,969,725 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475011,869,178 - 11,966,668 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fgd6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11173,130,709 - 173,293,607 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fgd6
911 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:40
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000059068
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)72154197735707405Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72092049437412865Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
D7Got19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2728,652,529 - 28,652,715 (+)MAPPERmRatBN7.2
Rnor_6.0735,006,804 - 35,006,989NCBIRnor6.0
Rnor_5.0735,064,533 - 35,064,718UniSTSRnor5.0
RGSC_v3.4731,229,121 - 31,229,307RGDRGSC3.4
RGSC_v3.4731,229,122 - 31,229,307UniSTSRGSC3.4
Celera725,745,564 - 25,745,749UniSTS
RGSC_v3.1731,249,393 - 31,249,578RGD
RH 3.4 Map7196.8UniSTS
RH 3.4 Map7196.8RGD
RH 2.0 Map7190.5RGD
Cytogenetic Map7q13UniSTS
AI231513  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2728,613,951 - 28,614,120 (+)MAPPERmRatBN7.2
Rnor_6.0734,968,221 - 34,968,389NCBIRnor6.0
Rnor_5.0735,026,246 - 35,026,414UniSTSRnor5.0
RGSC_v3.4731,176,364 - 31,176,532UniSTSRGSC3.4
Celera725,707,296 - 25,707,464UniSTS
RH 3.4 Map7193.9UniSTS
Cytogenetic Map7q13UniSTS
BF388111  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2728,656,488 - 28,656,675 (+)MAPPERmRatBN7.2
Rnor_6.0735,010,763 - 35,010,949NCBIRnor6.0
Rnor_5.0735,068,492 - 35,068,678UniSTSRnor5.0
RGSC_v3.4731,233,081 - 31,233,267UniSTSRGSC3.4
Celera725,749,523 - 25,749,709UniSTS
RH 3.4 Map7195.4UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 90 59 6 354 190 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000077666   ⟹   ENSRNOP00000074257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl730,491,897 - 30,593,918 (+)Ensembl
mRatBN7.2 Ensembl728,597,609 - 28,706,927 (+)Ensembl
Rnor_6.0 Ensembl734,952,011 - 35,063,929 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101771   ⟹   ENSRNOP00000081090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl730,484,600 - 30,595,806 (+)Ensembl
mRatBN7.2 Ensembl728,597,609 - 28,708,815 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114664   ⟹   ENSRNOP00000097286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl730,484,600 - 30,595,806 (+)Ensembl
mRatBN7.2 Ensembl728,597,609 - 28,712,456 (+)Ensembl
RefSeq Acc Id: NM_001137645   ⟹   NP_001131117
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,484,600 - 30,595,806 (+)NCBI
mRatBN7.2728,597,609 - 28,708,815 (+)NCBI
Rnor_6.0734,951,878 - 35,063,006 (+)NCBI
Rnor_5.0735,009,998 - 35,135,105 (+)NCBI
RGSC_v3.4731,160,021 - 31,286,379 (+)RGD
Celera725,690,957 - 25,801,895 (+)RGD
Sequence:
RefSeq Acc Id: XM_039079738   ⟹   XP_038935666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,494,286 - 30,599,898 (+)NCBI
mRatBN7.2728,610,349 - 28,712,908 (+)NCBI
RefSeq Acc Id: XM_063264098   ⟹   XP_063120168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,484,642 - 30,587,465 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001131117 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935666 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120168 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM16892 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074257.3
  ENSRNOP00000081090
  ENSRNOP00000081090.1
  ENSRNOP00000097286.2
RefSeq Acc Id: NP_001131117   ⟸   NM_001137645
- UniProtKB: A0A0G2K7L6 (UniProtKB/TrEMBL),   A0A8I6G5H4 (UniProtKB/TrEMBL),   A6IG06 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074257   ⟸   ENSRNOT00000077666
RefSeq Acc Id: XP_038935666   ⟸   XM_039079738
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000097286   ⟸   ENSRNOT00000114664
Ensembl Acc Id: ENSRNOP00000081090   ⟸   ENSRNOT00000101771
RefSeq Acc Id: XP_063120168   ⟸   XM_063264098
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AU60 (UniProtKB/TrEMBL)
Protein Domains
DH   FYVE-type   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7L6-F1-model_v2 AlphaFold A0A0G2K7L6 1-1406 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695153
Promoter ID:EPDNEW_R5677
Type:multiple initiation site
Name:Fgd6_1
Description:FYVE, RhoGEF and PH domain containing 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0734,951,990 - 34,952,050EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565609 AgrOrtholog
BioCyc Gene G2FUF-34373 BioCyc
Ensembl Genes ENSRNOG00000054515 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077666.3 UniProtKB/TrEMBL
  ENSRNOT00000101771 ENTREZGENE
  ENSRNOT00000101771.2 UniProtKB/TrEMBL
  ENSRNOT00000114664.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  FGD6_N_PH UniProtKB/TrEMBL
  FYVE_RhoGEF_PH UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:500824 UniProtKB/TrEMBL
NCBI Gene 500824 ENTREZGENE
PANTHER FACIOGENITAL DYSPLASIA PROTEIN UniProtKB/TrEMBL
  FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PhenoGen Fgd6 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054515 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A0G2K7L6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AU60 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5H4 ENTREZGENE, UniProtKB/TrEMBL
  A6IG06 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Fgd6  FYVE, RhoGEF and PH domain containing 6  RGD1565609_predicted  similar to FYVE, RhoGEF and PH domain containing 6 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565609_predicted  similar to FYVE, RhoGEF and PH domain containing 6 (predicted)  LOC500824  similar to FYVE, RhoGEF and PH domain containing 6  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500824  similar to FYVE, RhoGEF and PH domain containing 6      Symbol and Name status set to provisional 70820 PROVISIONAL