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Gene: Spag16 (sperm associated antigen 16) Rattus norvegicus

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Symbol:

Spag16

Name:

sperm associated antigen 16

RGD ID:

1565062

Description:

Predicted to enable protein kinase binding activity. Predicted to be involved in axoneme assembly. Predicted to act upstream of or within cerebrospinal fluid circulation; mucociliary clearance; and sperm axoneme assembly. Predicted to be located in axoneme and sperm flagellum. Predicted to be active in axonemal central apparatus. Orthologous to human SPAG16 (sperm associated antigen 16); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cadmium atom.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC501158; MGC187457; RGD1565062; similar to PF20; sperm-associated antigen 16 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SPAG16 (sperm associated antigen 16)	HGNC	Ensembl, HomoloGene, OrthoDB
Mus musculus (house mouse):	Spag16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Spag16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SPAG16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SPAG16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Spag16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SPAG16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SPAG16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Spag16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Spag16 (sperm associated antigen 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SPAG16 (sperm associated antigen 16)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SPAG16 (sperm associated antigen 16)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Spag16 (sperm associated antigen 16)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Spag16 (sperm associated antigen 16)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	spag16	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	spag16	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	78,782,596 - 79,702,265 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	78,782,614 - 78,877,630 (+)	Ensembl				GRCr8
mRatBN7.2	9	71,333,005 - 72,252,772 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	71,332,992 - 72,252,708 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	79,825,538 - 80,732,229 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	84,954,409 - 85,861,111 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	83,345,271 - 84,247,181 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	77,027,626 - 77,833,476 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	77,320,726 - 77,833,281 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	76,807,090 - 77,608,492 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	68,853,232 - 69,738,268 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	68,899,031 - 69,691,040 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

fetal akinesia deformation sequence syndrome 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-hexachlorocyclohexane (ISO)

bisphenol A (EXP)

cadmium atom (EXP)

cadmium dichloride (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

dicrotophos (ISO)

folic acid (ISO)

genistein (ISO)

glufosinate (ISO)

lead diacetate (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

methapyrilene (ISO)

N-acetyl-1,4-benzoquinone imine (ISO)

okadaic acid (ISO)

paracetamol (ISO)

phenobarbital (ISO)

potassium chromate (ISO)

quercetin (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axoneme assembly (ISO)

cell motility in response to calcium ion (ISO)

cerebrospinal fluid circulation (ISO)

cilium assembly (ISO)

cilium movement involved in cell motility (ISO)

microtubule sliding (ISO)

mucociliary clearance (ISO)

sperm axoneme assembly (ISO)

Cellular Component

axonemal central apparatus (ISO)

axoneme (ISO)

cytoplasm (ISO)

extracellular region (IEA)

manchette (ISO)

nucleus (ISO)

sperm flagellum (ISO)

Molecular Function

protein binding (ISO)

protein kinase binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12391165	PMID:12477932	PMID:15328412	PMID:16382026	PMID:17699735	PMID:18367677	PMID:19305393	PMID:20042536	PMID:27682589

Genomics

Comparative Map Data

Spag16
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	78,782,596 - 79,702,265 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	78,782,614 - 78,877,630 (+)	Ensembl				GRCr8
mRatBN7.2	9	71,333,005 - 72,252,772 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	71,332,992 - 72,252,708 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	79,825,538 - 80,732,229 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	84,954,409 - 85,861,111 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	83,345,271 - 84,247,181 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	77,027,626 - 77,833,476 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	77,320,726 - 77,833,281 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	76,807,090 - 77,608,492 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	68,853,232 - 69,738,268 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	68,899,031 - 69,691,040 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

SPAG16
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	213,284,464 - 214,410,501 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	213,284,389 - 214,410,501 (+)	Ensembl			hg38	GRCh38
GRCh37	2	214,149,188 - 215,275,225 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	213,857,361 - 214,983,470 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	213,974,671 - 215,100,728	NCBI
Celera	2	207,912,975 - 209,043,467 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI
HuRef	2	206,000,485 - 207,131,268 (+)	NCBI		HuRef
CHM1_1	2	214,155,231 - 215,281,740 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	213,765,296 - 214,894,995 (+)	NCBI		T2T-CHM13v2.0

Spag16
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	69,866,031 - 70,764,291 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	69,866,129 - 70,764,291 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	69,826,872 - 70,725,132 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	69,826,970 - 70,725,132 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	69,873,562 - 70,771,706 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	69,760,196 - 70,658,340 (+)	NCBI		MGSCv36	mm8
Celera	1	70,384,754 - 71,280,888 (+)	NCBI		Celera
Cytogenetic Map	1	C3	NCBI
cM Map	1	35.04	NCBI

Spag16
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	2,399,898 - 2,492,729 (-)	Ensembl
ChiLan1.0	NW_004955457	1,543,946 - 2,492,686 (-)	NCBI	ChiLan1.0	ChiLan1.0

SPAG16
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	115,905,940 - 117,032,765 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	115,920,901 - 117,047,727 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	100,539,441 - 101,666,204 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	219,014,837 - 220,139,499 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	219,014,837 - 220,139,314 (+)	Ensembl			panPan2	panpan1.1

SPAG16
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	20,782,855 - 21,690,523 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	20,782,867 - 21,690,333 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	21,661,941 - 21,681,718 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
Dog10K_Boxer_Tasha	37	21,711,108 - 22,448,683 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	20,775,567 - 21,698,785 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	20,775,576 - 21,698,595 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	20,681,773 - 21,588,806 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	20,630,489 - 21,539,329 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	20,648,305 - 21,556,000 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Spag16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	169,218,001 - 170,086,786 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936586	3,264,953 - 3,407,823 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPAG16
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	115,809,187 - 116,761,791 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	115,809,152 - 116,760,976 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	128,757,040 - 128,897,379 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SPAG16
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	99,044,097 - 100,215,884 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	100,301,727 - 100,360,834 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Spag16
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624765	2,548,748 - 2,886,134 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Spag16
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	143,567,906 - 144,091,516 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Spag16
5871 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	21
Count of miRNA genes:	20
Interacting mature miRNAs:	21
Transcripts:	ENSRNOT00000068450
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56047863	101047863	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	40029925	85029925	Rat
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	63376862	108376862	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	44458256	99506504	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	65657365	108376720	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	44458256	85262605	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	29567664	83835942	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	41720295	86720295	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	64220169	109220169	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	44458256	121768150	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	64220169	109220169	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	64220169	109220169	Rat
1581517	Bp284	Blood pressure QTL 284			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	39220186	84220186	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	68875497	121768150	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	48718864	108376862	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	40029925	85029925	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	54506504	99506504	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	64220169	109220169	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	34960590	79960590	Rat

Markers in Region

D9Rat114

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	79,578,067 - 79,578,300 (+)	Marker Load Pipeline
mRatBN7.2	9	72,128,565 - 72,128,798 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	77,708,311 - 77,708,543	NCBI	Rnor6.0
Rnor_5.0	9	77,483,053 - 77,483,285	UniSTS	Rnor5.0
RGSC_v3.4	9	69,613,562 - 69,613,795	RGD	RGSC3.4
RGSC_v3.4	9	69,613,563 - 69,613,795	UniSTS	RGSC3.4
Celera	9	69,567,009 - 69,567,241	UniSTS
RGSC_v3.1	9	69,760,533 - 69,760,986	RGD
SHRSP x BN Map	9	48.9699	UniSTS
SHRSP x BN Map	9	48.9699	RGD
Cytogenetic Map	9	q32	UniSTS

AU048609

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	72,111,216 - 72,111,514 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	77,691,448 - 77,691,743	NCBI	Rnor6.0
Rnor_5.0	9	77,466,190 - 77,466,485	UniSTS	Rnor5.0
RGSC_v3.4	9	69,596,218 - 69,596,513	UniSTS	RGSC3.4
Celera	9	69,549,262 - 69,549,557	UniSTS
Cytogenetic Map	9	q32	UniSTS

AU049395

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	71,653,131 - 71,653,381 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	77,231,336 - 77,231,585	NCBI	Rnor6.0
Rnor_5.0	9	77,011,102 - 77,011,351	UniSTS	Rnor5.0
RGSC_v3.4	9	69,059,045 - 69,059,294	UniSTS	RGSC3.4
Cytogenetic Map	9	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
1	1	7	93	12	23	4	8	4	47	18	1	90	23	49	19	8	8

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005488954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005488955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000068450 ⟹ ENSRNOP00000063278

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	71,332,992 - 72,252,708 (+)	Ensembl
Rnor_6.0 Ensembl	9	77,320,726 - 77,833,281 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000089203 ⟹ ENSRNOP00000075031

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	78,782,614 - 78,877,630 (+)	Ensembl
mRatBN7.2 Ensembl	9	71,332,992 - 71,428,036 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110164 ⟹ ENSRNOP00000091568

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	71,333,084 - 71,743,649 (+)	Ensembl

RefSeq Acc Id:

NM_001134728 ⟹ NP_001128200

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,898,473 - 79,702,265 (+)	NCBI
mRatBN7.2	9	71,448,879 - 72,252,772 (+)	NCBI
Rnor_6.0	9	77,027,626 - 77,833,476 (+)	NCBI
Rnor_5.0	9	76,807,090 - 77,608,492 (+)	NCBI
RGSC_v3.4	9	68,853,232 - 69,738,268 (+)	RGD
Celera	9	68,899,031 - 69,691,040 (+)	RGD

Sequence:

show sequence

CTTGAGCTCACAGATCAGTCTTTATTATTCTGTGTGAGATGCGATGGTCCATCCCCAGTCAATG
ATCTTCAATGATCCTGCCCTTCTCCAGGGCATCTATTTAAACCCTAGGTTTTGATTCTTGATGG
TATGGGCCTCTTTTGCCAGTTGGCCAAGGGGGAGCGTGAAGGCTCGAGCTGAGATTTAAAATCA
TCTCAACTGCCTATCTTCCTCCTGGATGTTTACACCGCCTATCTTCCTCCTGGATGCTTACTCT
GACGCCATGAGTATCGTCAGCCTGTGAATGTCGCCGAAGCGGTTGTTGAAAAGCTTGAACTCAG
CCCTTCGGGCTCTGTACGCATATACTCCATGTTTGTACTTTCCCAGAGACCAACTGTCTGCTTG
AGGAGGACTCAGAATTTCCTGTAGATATGCAACCTGATCCAAACTTGACTGCATGTACAGAGAG
CCTTCCGACTGCAAAATTTGACTACAGGCTAAACAACATTTTCAGACTTCATGAACTCCCAGTG
AGCTGTATCGTCATGCACCCCTTCAGAGACTATCTGGTCTCCTGTAGTGAGGATCGTCTCTGGA
AGATGGTGGGCCTCCCAAAGGGCAATGTAATTCTTACGGGATCTGGCCACAGTGACTGGCTGTC
CGACTGCTGTTTCCATCCGAGTGGCAGCAAATTGGCTACCTCAAGTGGTGACAGCACAATTAAA
CTGTGGGATCTCTCAAAAGGTGAATGCATCTTGACCTTCGCAGGACACAACCATGCCATATGGT
CCTGCACATGGCACTCTTGTGGTGATTTCGTGGCTTCTGCCTCACTGGATATGACAAGTAAAAT
CTGGGATGTTAATAGTGAGCGGTGCAGATATACTTTGTATGGACACACGGACTCTGTGAACAGC
ATTGAGTTTTTCCCTTTCTCCAACACTCTTCTCACGGCTTCTGCAGACAAGACCTTGTCTGTGT
GGGATGCACGAACAGGTAAATGTGAGCAGTCTCTGTATGGCCACATGCACTCCGTCAATGATGC
CACCTTCACACCTAGGGGTCACATACTAGCATCCTGTGATTCCCGTGGAGTTATAAAGCTATGG
GACTTCCGGAAGCTCATTCCAATCGTGTCCATTGATGTGGGTCCAAGTCCTGGCAACGAGGTGA
ATTTTGACCCATCAGGTCGAGTTTTAGCTCAGGCGAGTGCCAACGGGATTATCCATTTGCTGGA
TCTTAAATCTGGGCAAATTCACAAACTGGTGGGCCATGAGAGTGAAGTGCACACTGTGATATTT
TCCCACCGTGCAGAGAATCTGTACTCTGGTGGTTCTGACGGCACCATTCGGTTGTGGCTCTGAT
CAGCAAAAGCATACCCTGATGCAAAGGGCATTCCCTCCACAGCTCAAAAATGCTCCATACAGTC
TGCTTACAAGCCAGCAACTAGCTGGATATAACGACCAATAAATAAAATATTTGTTTTGAAACAA
GCTTTGGGTGAATACTATATAACCCCTACTGTTACAAATAAAAATTATAACTTTTTCTTCATTA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001401616 ⟹ NP_001388545

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,616 - 79,702,232 (+)	NCBI
mRatBN7.2	9	71,333,014 - 72,252,739 (+)	NCBI

RefSeq Acc Id:

XM_039084101 ⟹ XP_038940029

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,702,263 (+)	NCBI
mRatBN7.2	9	71,333,013 - 72,252,740 (+)	NCBI

RefSeq Acc Id:

XM_039084102 ⟹ XP_038940030

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,702,263 (+)	NCBI
mRatBN7.2	9	71,333,012 - 72,252,740 (+)	NCBI

RefSeq Acc Id:

XM_039084103 ⟹ XP_038940031

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,702,263 (+)	NCBI
mRatBN7.2	9	71,333,011 - 72,252,741 (+)	NCBI

RefSeq Acc Id:

XM_039084104 ⟹ XP_038940032

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,374,044 (+)	NCBI
mRatBN7.2	9	71,333,012 - 71,925,317 (+)	NCBI

RefSeq Acc Id:

XM_063267621 ⟹ XP_063123691

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,702,263 (+)	NCBI

RefSeq Acc Id:

XM_063267623 ⟹ XP_063123693

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 78,986,700 (+)	NCBI

RefSeq Acc Id:

XM_063267624 ⟹ XP_063123694

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	79,088,686 - 79,702,263 (+)	NCBI

RefSeq Acc Id:

XR_005488954

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,241,820 (+)	NCBI
mRatBN7.2	9	71,333,010 - 71,792,237 (+)	NCBI

RefSeq Acc Id:

XR_005488955

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,193,238 (+)	NCBI
mRatBN7.2	9	71,333,010 - 71,743,655 (+)	NCBI

RefSeq Acc Id:

XR_010054628

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	78,782,596 - 79,000,201 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001128200	(Get FASTA)	NCBI Sequence Viewer
	NP_001388545	(Get FASTA)	NCBI Sequence Viewer
	XP_038940029	(Get FASTA)	NCBI Sequence Viewer
	XP_038940030	(Get FASTA)	NCBI Sequence Viewer
	XP_038940031	(Get FASTA)	NCBI Sequence Viewer
	XP_038940032	(Get FASTA)	NCBI Sequence Viewer
	XP_063123691	(Get FASTA)	NCBI Sequence Viewer
	XP_063123693	(Get FASTA)	NCBI Sequence Viewer
	XP_063123694	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58603	(Get FASTA)	NCBI Sequence Viewer
	EDL75271	(Get FASTA)	NCBI Sequence Viewer
	EDL75272	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063278
	ENSRNOP00000063278.5
	ENSRNOP00000075031.1

RefSeq Acc Id:	NP_001128200 ⟸ NM_001134728
- Peptide Label:	isoform 2
- UniProtKB:	B0BMX7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQPDPNLTACTESLPTAKFDYRLNNIFRLHELPVSCIVMHPFRDYLVSCSEDRLWKMVGLPKGN VILTGSGHSDWLSDCCFHPSGSKLATSSGDSTIKLWDLSKGECILTFAGHNHAIWSCTWHSCGD FVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNTLLTASADKTLSVWDARTGKCE QSLYGHMHSVNDATFTPRGHILASCDSRGVIKLWDFRKLIPIVSIDVGPSPGNEVNFDPSGRVL AQASANGIIHLLDLKSGQIHKLVGHESEVHTVIFSHRAENLYSGGSDGTIRLWL hide sequence

Ensembl Acc Id:

ENSRNOP00000063278 ⟸ ENSRNOT00000068450

RefSeq Acc Id:	XP_038940031 ⟸ XM_039084103
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038940030 ⟸ XM_039084102
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038940032 ⟸ XM_039084104
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038940029 ⟸ XM_039084101
- Peptide Label:	isoform X2

RefSeq Acc Id:	NP_001388545 ⟸ NM_001401616
- Peptide Label:	isoform 1
- UniProtKB:	F1M3E0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000075031 ⟸ ENSRNOT00000089203

Ensembl Acc Id:

ENSRNOP00000091568 ⟸ ENSRNOT00000110164

RefSeq Acc Id:	XP_063123691 ⟸ XM_063267621
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063123693 ⟸ XM_063267623
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6AFW5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063123694 ⟸ XM_063267624
- Peptide Label:	isoform X7

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M3E0-F1-model_v2	AlphaFold	F1M3E0	1-274	view protein structure
AF-A0A0G2K9K6-F1-model_v2	AlphaFold	A0A0G2K9K6	1-406	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565062	AgrOrtholog
BioCyc Gene	G2FUF-27264	BioCyc
Ensembl Genes	ENSRNOG00000042609	Ensembl
	ENSRNOG00000054475	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000075101	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000068450	ENTREZGENE
	ENSRNOT00000068450.5	UniProtKB/TrEMBL
	ENSRNOT00000089203	ENTREZGENE
	ENSRNOT00000089203.3	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7133303	IMAGE-MGC_LOAD
InterPro	G-protein_beta_WD-40_rep	UniProtKB/TrEMBL
	WD-F-box_domain-protein	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
MGC_CLONE	MGC:187457	IMAGE-MGC_LOAD
NCBI Gene	501158	ENTREZGENE
PANTHER	SPERM-ASSOCIATED ANTIGEN 16 PROTEIN	UniProtKB/TrEMBL
	WD40 REPEAT PF20	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PhenoGen	Spag16	PhenoGen
PRINTS	GPROTEINBRPT	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_1	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000042609	RatGTEx
	ENSRNOG00000054475	RatGTEx
	ENSRNOG00000075101	RatGTEx
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	A0A0G2K9K6_RAT	UniProtKB/TrEMBL
	A0A8I6AFW5	ENTREZGENE
	B0BMX7	ENTREZGENE, UniProtKB/TrEMBL
	F1M3E0	ENTREZGENE
UniProt Secondary	F1M3E0	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Spag16	sperm associated antigen 16	RGD1565062_predicted	similar to PF20 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565062_predicted	similar to PF20 (predicted)	LOC501158	similar to PF20	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC501158	similar to PF20			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar