Tmtc1 (transmembrane O-mannosyltransferase targeting cadherins 1) - Rat Genome Database

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Pathways
Gene: Tmtc1 (transmembrane O-mannosyltransferase targeting cadherins 1) Rattus norvegicus
Analyze
Symbol: Tmtc1
Name: transmembrane O-mannosyltransferase targeting cadherins 1
RGD ID: 1564868
Description: Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in protein O-linked glycosylation via mannose. Predicted to be located in endoplasmic reticulum and membrane. Orthologous to human TMTC1 (transmembrane O-mannosyltransferase targeting cadherins 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362465; RGD1564868; similar to ARG99 homolog; transmembrane and tetratricopeptide repeat containing 1; transmembrane and TPR repeat-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84182,874,350 - 183,089,408 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4182,878,802 - 183,102,532 (-)EnsemblGRCr8
mRatBN7.24181,142,937 - 181,357,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4181,146,251 - 181,359,289 (-)EnsemblmRatBN7.2
Rnor_6.04182,620,132 - 182,845,620 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4182,625,386 - 182,844,291 (-)Ensemblrn6Rnor6.0
Rnor_5.04246,754,566 - 246,980,691 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44185,853,778 - 186,069,316 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4169,634,339 - 169,841,680 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glufosinate  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
leflunomide  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
temozolomide  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18614015   PMID:28973932  


Genomics

Comparative Map Data
Tmtc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84182,874,350 - 183,089,408 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4182,878,802 - 183,102,532 (-)EnsemblGRCr8
mRatBN7.24181,142,937 - 181,357,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4181,146,251 - 181,359,289 (-)EnsemblmRatBN7.2
Rnor_6.04182,620,132 - 182,845,620 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4182,625,386 - 182,844,291 (-)Ensemblrn6Rnor6.0
Rnor_5.04246,754,566 - 246,980,691 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44185,853,778 - 186,069,316 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4169,634,339 - 169,841,680 (-)NCBICelera
Cytogenetic Map4q44NCBI
TMTC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381229,500,813 - 29,784,759 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1229,500,840 - 29,784,759 (-)Ensemblhg38GRCh38
GRCh371229,653,746 - 29,937,692 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361229,545,024 - 29,828,959 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1234,799,099 - 35,083,077 (-)NCBICelera
Cytogenetic Map12p11.22NCBI
HuRef1229,422,040 - 29,706,478 (-)NCBIHuRef
CHM1_11229,618,952 - 29,902,841 (-)NCBICHM1_1
T2T-CHM13v2.01229,372,944 - 29,656,989 (-)NCBIT2T-CHM13v2.0
Tmtc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396148,133,928 - 148,346,222 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6148,133,928 - 148,345,887 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386148,232,430 - 148,444,770 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6148,232,430 - 148,444,389 (-)Ensemblmm10GRCm38
MGSCv376148,180,952 - 148,392,874 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366148,193,842 - 148,401,522 (-)NCBIMGSCv36mm8
Celera6151,264,572 - 151,479,660 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map678.49NCBI
Tmtc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555055,226,550 - 5,449,117 (+)Ensembl
ChiLan1.0NW_0049555055,200,900 - 5,454,785 (+)NCBIChiLan1.0ChiLan1.0
TMTC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21067,019,537 - 67,302,439 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11267,015,260 - 67,303,984 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01256,517,067 - 56,805,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11259,145,232 - 59,430,255 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1259,145,228 - 59,424,231 (+)EnsemblpanPan2panpan1.1
TMTC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12718,252,642 - 18,519,802 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2718,191,118 - 18,518,974 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2727,890,260 - 28,157,025 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02718,440,404 - 18,710,374 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2718,440,180 - 18,705,879 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12718,253,883 - 18,519,964 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02718,279,905 - 18,549,299 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02728,042,107 - 28,312,102 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tmtc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494580,126,963 - 80,380,197 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367601,558,997 - 1,806,386 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367601,558,776 - 1,807,216 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMTC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl543,913,693 - 44,218,049 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1543,913,710 - 44,222,899 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2547,514,487 - 47,533,962 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMTC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11129,207,946 - 29,494,691 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1129,213,956 - 29,493,489 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660695,537,900 - 5,824,854 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmtc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247785,961,692 - 6,208,993 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247785,961,700 - 6,211,525 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tmtc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v165,873,166 - 5,975,697 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:144
Count of miRNA genes:87
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000002535, ENSRNOT00000064320
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
D4Got156  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24181,192,162 - 181,192,354 (+)MAPPERmRatBN7.2
Rnor_6.04182,668,008 - 182,668,199NCBIRnor6.0
Rnor_5.04246,802,436 - 246,802,627UniSTSRnor5.0
RGSC_v3.44185,900,256 - 185,900,447RGDRGSC3.4
RGSC_v3.44185,900,256 - 185,900,447UniSTSRGSC3.4
Celera4169,677,483 - 169,677,674UniSTS
RGSC_v3.14186,145,380 - 186,145,571RGD
RH 3.4 Map41125.62RGD
RH 3.4 Map41125.62UniSTS
RH 2.0 Map41159.0RGD
Cytogenetic Map4q44UniSTS
RH130651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24181,287,548 - 181,287,734 (+)MAPPERmRatBN7.2
Rnor_6.04182,768,410 - 182,768,595NCBIRnor6.0
Rnor_5.04246,903,053 - 246,903,238UniSTSRnor5.0
RGSC_v3.44185,996,108 - 185,996,293UniSTSRGSC3.4
Celera4169,772,583 - 169,772,768UniSTS
RH 3.4 Map41119.1UniSTS
Cytogenetic Map4q44UniSTS
BF402097  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24181,179,816 - 181,179,989 (+)MAPPERmRatBN7.2
Rnor_6.04182,655,662 - 182,655,834NCBIRnor6.0
Rnor_5.04246,790,090 - 246,790,262UniSTSRnor5.0
RGSC_v3.44185,887,910 - 185,888,082UniSTSRGSC3.4
Celera4169,665,136 - 169,665,308UniSTS
RH 3.4 Map41102.8UniSTS
Cytogenetic Map4q44UniSTS
AI104090  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24181,270,223 - 181,270,369 (+)MAPPERmRatBN7.2
Rnor_6.04182,746,165 - 182,746,310NCBIRnor6.0
Rnor_5.04246,880,519 - 246,880,664UniSTSRnor5.0
RGSC_v3.44185,978,112 - 185,978,257UniSTSRGSC3.4
Celera4169,755,259 - 169,755,404UniSTS
RH 3.4 Map2055.73UniSTS
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 52 59 6 316 152 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000064320   ⟹   ENSRNOP00000061944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,878,802 - 183,102,532 (-)Ensembl
mRatBN7.2 Ensembl4181,146,251 - 181,359,289 (-)Ensembl
Rnor_6.0 Ensembl4182,625,386 - 182,844,291 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114970   ⟹   ENSRNOP00000084348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,878,802 - 183,089,418 (-)Ensembl
mRatBN7.2 Ensembl4181,146,251 - 181,359,289 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144032   ⟹   ENSRNOP00000100951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,878,802 - 183,089,418 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000151996   ⟹   ENSRNOP00000107854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,883,865 - 183,089,418 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155280   ⟹   ENSRNOP00000111384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,878,802 - 183,089,418 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158656   ⟹   ENSRNOP00000103955
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,885,464 - 183,089,418 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000160308   ⟹   ENSRNOP00000109563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4182,878,802 - 183,089,418 (-)Ensembl
RefSeq Acc Id: XM_039108899   ⟹   XP_038964827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84182,874,350 - 183,089,408 (-)NCBI
mRatBN7.24181,142,937 - 181,357,979 (-)NCBI
RefSeq Acc Id: XM_039108900   ⟹   XP_038964828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84182,874,350 - 183,089,408 (-)NCBI
mRatBN7.24181,142,937 - 181,357,979 (-)NCBI
RefSeq Acc Id: XM_039108901   ⟹   XP_038964829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84182,891,331 - 183,089,408 (-)NCBI
mRatBN7.24181,160,490 - 181,357,979 (-)NCBI
RefSeq Acc Id: XM_039108902   ⟹   XP_038964830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84182,933,766 - 183,089,408 (-)NCBI
mRatBN7.24181,202,356 - 181,357,979 (-)NCBI
RefSeq Acc Id: XM_063286869   ⟹   XP_063142939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84182,884,545 - 183,089,408 (-)NCBI
RefSeq Acc Id: XM_063286870   ⟹   XP_063142940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84182,874,350 - 183,089,372 (-)NCBI
Ensembl Acc Id: ENSRNOP00000061944   ⟸   ENSRNOT00000064320
RefSeq Acc Id: XP_038964828   ⟸   XM_039108900
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZZ24 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964827   ⟸   XM_039108899
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038964829   ⟸   XM_039108901
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038964830   ⟸   XM_039108902
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000084348   ⟸   ENSRNOT00000114970
RefSeq Acc Id: XP_063142940   ⟸   XM_063286870
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142939   ⟸   XM_063286869
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000111384   ⟸   ENSRNOT00000155280
Ensembl Acc Id: ENSRNOP00000107854   ⟸   ENSRNOT00000151996
Ensembl Acc Id: ENSRNOP00000100951   ⟸   ENSRNOT00000144032
Ensembl Acc Id: ENSRNOP00000103955   ⟸   ENSRNOT00000158656
Ensembl Acc Id: ENSRNOP00000109563   ⟸   ENSRNOT00000160308
Protein Domains
DUF1736

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2M3-F1-model_v2 AlphaFold D4A2M3 1-880 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564868 AgrOrtholog
BioCyc Gene G2FUF-42402 BioCyc
BioCyc Pathway PWY-7922 [protein O-mannosylation II (mammals, core M1 and core M2)] BioCyc
  PWY-7979 [protein O-mannosylation III (mammals, core M3)] BioCyc
BioCyc Pathway Image PWY-7922 BioCyc
  PWY-7979 BioCyc
Ensembl Genes ENSRNOG00000001854 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064320.6 UniProtKB/TrEMBL
  ENSRNOT00000114970 ENTREZGENE
  ENSRNOT00000114970.2 UniProtKB/TrEMBL
  ENSRNOT00000144032 ENTREZGENE
  ENSRNOT00000144032.1 UniProtKB/TrEMBL
  ENSRNOT00000151996.1 UniProtKB/TrEMBL
  ENSRNOT00000155280.1 UniProtKB/TrEMBL
  ENSRNOT00000158656 ENTREZGENE
  ENSRNOT00000158656.1 UniProtKB/TrEMBL
  ENSRNOT00000160308 ENTREZGENE
  ENSRNOT00000160308.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro DUF1736 UniProtKB/TrEMBL
  TMTC_O-mannosyl-trnsfr UniProtKB/TrEMBL
  TPR-like_helical UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene 362465 ENTREZGENE
PANTHER PROTEIN O-MANNOSYL-TRANSFERASE TMTC1 UniProtKB/TrEMBL
  PTHR44809 UniProtKB/TrEMBL
Pfam DUF1736 UniProtKB/TrEMBL
  TPR_11 UniProtKB/TrEMBL
  TPR_12 UniProtKB/TrEMBL
  TPR_16 UniProtKB/TrEMBL
  TPR_19 UniProtKB/TrEMBL
PhenoGen Tmtc1 PhenoGen
PROSITE TPR UniProtKB/TrEMBL
  TPR_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001854 RatGTEx
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8I5ZZ24 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJ67_RAT UniProtKB/TrEMBL
  A0ABK0LKL3_RAT UniProtKB/TrEMBL
  A0ABK0LRI4_RAT UniProtKB/TrEMBL
  A0ABK0LYI6_RAT UniProtKB/TrEMBL
  A0ABK0M0Z1_RAT UniProtKB/TrEMBL
  D4A2M3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Tmtc1  transmembrane O-mannosyltransferase targeting cadherins 1  Tmtc1  transmembrane and tetratricopeptide repeat containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Tmtc1  transmembrane and tetratricopeptide repeat containing 1  RGD1564868_predicted  similar to ARG99 homolog (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564868_predicted  similar to ARG99 homolog (predicted)  LOC362465  similar to ARG99 homolog  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC362465  similar to ARG99 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL