Ubl5 (ubiquitin-like 5) - Rat Genome Database

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Gene: Ubl5 (ubiquitin-like 5) Rattus norvegicus
Analyze
Symbol: Ubl5
Name: ubiquitin-like 5
RGD ID: 1564644
Description: Predicted to enable protein tag activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBL5 (ubiquitin like 5); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beacon; LOC500954; Ubiquitin-Like 5 Protein; ubiquitin-like protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,457,738 - 27,461,458 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2819,181,504 - 19,185,224 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,181,615 - 19,185,217 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx823,201,812 - 23,205,536 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,499,651 - 21,503,375 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,411,250 - 19,414,970 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,663,257 - 21,665,049 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,663,325 - 21,665,038 (+)Ensemblrn6Rnor6.0
Rnor_5.0821,719,122 - 21,721,110 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,663,626 - 19,665,339 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,578,802 - 20,580,515 (+)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11161819   PMID:15942675   PMID:16157417   PMID:17097194   PMID:24270810  


Genomics

Comparative Map Data
Ubl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,457,738 - 27,461,458 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2819,181,504 - 19,185,224 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,181,615 - 19,185,217 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx823,201,812 - 23,205,536 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,499,651 - 21,503,375 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,411,250 - 19,414,970 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,663,257 - 21,665,049 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,663,325 - 21,665,038 (+)Ensemblrn6Rnor6.0
Rnor_5.0821,719,122 - 21,721,110 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,663,626 - 19,665,339 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,578,802 - 20,580,515 (+)NCBICelera
Cytogenetic Map8q13NCBI
UBL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,827,918 - 9,830,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,827,892 - 9,830,137 (+)Ensemblhg38GRCh38
GRCh37199,938,594 - 9,940,791 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,799,568 - 9,801,797 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34199,799,613 - 9,801,791NCBI
Celera199,833,993 - 9,836,222 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,519,189 - 9,521,430 (+)NCBIHuRef
CHM1_1199,938,269 - 9,940,510 (+)NCBICHM1_1
T2T-CHM13v2.0199,953,519 - 9,956,279 (+)NCBIT2T-CHM13v2.0
Ubl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,554,013 - 20,558,436 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,554,174 - 20,558,436 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38920,642,717 - 20,647,140 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,642,878 - 20,647,140 (+)Ensemblmm10GRCm38
MGSCv37920,447,762 - 20,451,233 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36920,393,720 - 20,397,191 (+)NCBIMGSCv36mm8
Celera917,913,763 - 17,917,234 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.6NCBI
Ubl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,242,733 - 1,244,238 (+)Ensembl
ChiLan1.0NW_0049554951,242,733 - 1,244,238 (+)NCBIChiLan1.0ChiLan1.0
UBL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22014,746,291 - 14,748,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11913,749,258 - 13,751,463 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,382,423 - 9,384,710 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,045,605 - 10,047,697 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,045,636 - 10,047,697 (+)EnsemblpanPan2panpan1.1
UBL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12051,174,741 - 51,176,401 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2051,174,741 - 51,176,292 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2051,038,534 - 51,040,198 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02051,696,125 - 51,697,789 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,696,125 - 51,697,676 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,903,731 - 50,905,395 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,328,193 - 51,329,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,569,994 - 51,571,658 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ubl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118210,049,581 - 210,051,242 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659303,252 - 305,122 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936659303,279 - 305,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl268,706,197 - 68,708,011 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1268,702,478 - 68,708,012 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,035,905 - 69,037,795 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.168,899,889 - 8,902,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl68,899,970 - 8,902,459 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607411,187,078 - 11,189,647 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,112,794 - 2,114,392 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248282,112,694 - 2,114,392 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ubl5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1816,913,894 - 16,915,708 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ubl5
17 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:79
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000027749
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat

Markers in Region
RH130060  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2819,184,054 - 19,185,164 (+)MAPPERmRatBN7.2
Rnor_6.0821,663,883 - 21,664,992NCBIRnor6.0
Rnor_5.0821,719,944 - 21,721,053UniSTSRnor5.0
RGSC_v3.4819,664,184 - 19,665,293UniSTSRGSC3.4
Celera820,579,360 - 20,580,469UniSTS
Cytogenetic Map8q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027749   ⟹   ENSRNOP00000027749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl821,663,325 - 21,665,038 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101563   ⟹   ENSRNOP00000097218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl819,181,615 - 19,185,217 (+)Ensembl
RefSeq Acc Id: NM_001048243   ⟹   NP_001041708
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,459,665 - 27,461,458 (+)NCBI
mRatBN7.2819,183,431 - 19,185,224 (+)NCBI
Rnor_6.0821,663,325 - 21,665,038 (+)NCBI
Rnor_5.0821,719,122 - 21,721,110 (+)NCBI
RGSC_v3.4819,663,626 - 19,665,339 (+)RGD
Celera820,578,802 - 20,580,515 (+)RGD
Sequence:
RefSeq Acc Id: NM_001393882   ⟹   NP_001380811
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,459,665 - 27,461,458 (+)NCBI
mRatBN7.2819,183,431 - 19,185,224 (+)NCBI
RefSeq Acc Id: NM_001393883   ⟹   NP_001380812
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,457,738 - 27,461,458 (+)NCBI
mRatBN7.2819,181,504 - 19,185,224 (+)NCBI
RefSeq Acc Id: XM_063265961   ⟹   XP_063122031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,459,680 - 27,461,444 (+)NCBI
RefSeq Acc Id: NP_001041708   ⟸   NM_001048243
- UniProtKB: A9UMW0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027749   ⟸   ENSRNOT00000027749
Ensembl Acc Id: ENSRNOP00000097218   ⟸   ENSRNOT00000101563
RefSeq Acc Id: NP_001380812   ⟸   NM_001393883
- UniProtKB: A9UMW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380811   ⟸   NM_001393882
- UniProtKB: A9UMW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122031   ⟸   XM_063265961
- Peptide Label: isoform X1
Protein Domains
Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A9UMW0-F1-model_v2 AlphaFold A9UMW0 1-73 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695760
Promoter ID:EPDNEW_R6285
Type:initiation region
Name:Ubl5_1
Description:ubiquitin-like 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0821,663,290 - 21,663,350EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564644 AgrOrtholog
BioCyc Gene G2FUF-31467 BioCyc
Ensembl Genes ENSRNOG00000020442 Ensembl
  ENSRNOG00000069661 Ensembl
  ENSRNOG00000079775 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000133900.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7936655 IMAGE-MGC_LOAD
InterPro Hub1/Ubl5 UniProtKB/TrEMBL
  Ubiquitin UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:500954 UniProtKB/TrEMBL
MGC_CLONE MGC:188356 IMAGE-MGC_LOAD
NCBI Gene 500954 ENTREZGENE
PANTHER PTHR13042 UniProtKB/TrEMBL
Pfam ubiquitin UniProtKB/TrEMBL
PhenoGen Ubl5 PhenoGen
RatGTEx ENSRNOG00000020442 RatGTEx
  ENSRNOG00000069661 RatGTEx
  ENSRNOG00000079775 RatGTEx
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0ABK0LJN3_RAT UniProtKB/TrEMBL
  A9UMW0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Ubl5  ubiquitin-like 5  LOC500954  Ubiquitin-Like 5 Protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC500954  Ubiquitin-Like 5 Protein      Symbol and Name status set to provisional 70820 PROVISIONAL