Galnt4 (polypeptide N-acetylgalactosaminyltransferase 4) - Rat Genome Database

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Gene: Galnt4 (polypeptide N-acetylgalactosaminyltransferase 4) Rattus norvegicus
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Symbol: Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
RGD ID: 1564589
Description: Orthologous to human GALNT4 (polypeptide N-acetylgalactosaminyltransferase 4); PARTICIPATES IN O-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC125173; polypeptide GalNAc transferase-T4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
RGD Orthologs
Human
Mouse
Chinchilla
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8735,811,904 - 35,814,445 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2733,925,229 - 33,927,770 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx735,914,463 - 35,917,004 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0738,096,228 - 38,098,769 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0737,829,311 - 37,831,852 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0741,305,437 - 41,309,621 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0741,341,613 - 41,347,240 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4736,684,516 - 36,687,057 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera730,941,312 - 30,943,853 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9804815   PMID:12506059   PMID:19199708   PMID:29208955  


Genomics

Comparative Map Data
Galnt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8735,811,904 - 35,814,445 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2733,925,229 - 33,927,770 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx735,914,463 - 35,917,004 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0738,096,228 - 38,098,769 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0737,829,311 - 37,831,852 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0741,305,437 - 41,309,621 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0741,341,613 - 41,347,240 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4736,684,516 - 36,687,057 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera730,941,312 - 30,943,853 (+)NCBICelera
Cytogenetic Map7q13NCBI
GALNT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381289,519,412 - 89,524,796 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1289,519,412 - 89,524,796 (-)Ensemblhg38GRCh38
GRCh371289,913,189 - 89,918,573 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361288,437,320 - 88,442,666 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341288,415,659 - 88,421,003NCBI
Celera1289,584,860 - 89,590,206 (-)NCBICelera
Cytogenetic Map12q21.33NCBI
HuRef1286,979,065 - 86,984,460 (-)NCBIHuRef
CHM1_11289,878,213 - 89,883,608 (-)NCBICHM1_1
T2T-CHM13v2.01289,501,268 - 89,506,652 (-)NCBIT2T-CHM13v2.0
Galnt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391098,943,997 - 98,949,109 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1098,944,021 - 98,949,109 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381099,108,135 - 99,113,247 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1099,108,159 - 99,113,247 (+)Ensemblmm10GRCm38
MGSCv371098,570,769 - 98,575,881 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361098,537,826 - 98,542,935 (+)NCBIMGSCv36mm8
Celera10101,080,064 - 101,085,176 (+)NCBICelera
Cytogenetic Map10C3NCBI
cM Map1051.06NCBI
Galnt4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049566661,955 - 3,520 (-)Ensembl
ChiLan1.0NW_00495666667 - 3,521 (-)NCBIChiLan1.0ChiLan1.0
GALNT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl593,132,675 - 93,135,709 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1593,133,008 - 93,138,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Galnt4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475017,203,991 - 17,208,304 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Galnt4
18 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72092049437412865Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 49 66 136 94 11 48 35 32 17 17

Sequence


RefSeq Acc Id: NM_001025053   ⟹   NP_001020224
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8735,811,904 - 35,814,445 (+)NCBI
mRatBN7.2733,925,229 - 33,927,770 (+)NCBI
Rnor_6.0741,305,807 - 41,308,348 (+)NCBI
Rnor_5.0741,341,613 - 41,347,240 (+)NCBI
RGSC_v3.4736,684,516 - 36,687,057 (+)RGD
Celera730,941,312 - 30,943,853 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001020224 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI05819 (Get FASTA)   NCBI Sequence Viewer  
  BAD93348 (Get FASTA)   NCBI Sequence Viewer  
  EDM16819 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020224   ⟸   NM_001025053
- UniProtKB: Q3KR95 (UniProtKB/TrEMBL),   Q58A68 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Ricin B lectin


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564589 AgrOrtholog
BioCyc Gene G2FUF-34272 BioCyc
BioCyc Pathway PWY-7433 [mucin core 1 and core 2 O-glycosylation] BioCyc
  PWY-7435 [mucin core 3 and core 4 O-glycosylation] BioCyc
BioCyc Pathway Image PWY-7433 BioCyc
  PWY-7435 BioCyc
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
  Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368805 IMAGE-MGC_LOAD
InterPro GalNAc-T UniProtKB/TrEMBL
  Glyco_trans_2 UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
  Ricin_B-like_lectins UniProtKB/TrEMBL
  Ricin_B_lectin UniProtKB/TrEMBL
KEGG Report rno:500826 UniProtKB/TrEMBL
MGC_CLONE MGC:125173 IMAGE-MGC_LOAD
NCBI Gene 500826 ENTREZGENE
PANTHER N-ACETYLGALACTOSAMINYLTRANSFERASE UniProtKB/TrEMBL
  POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 4 UniProtKB/TrEMBL
Pfam Glycos_transf_2 UniProtKB/TrEMBL
  Ricin_B_lectin UniProtKB/TrEMBL
PhenoGen Galnt4 PhenoGen
PROSITE RICIN_B_LECTIN UniProtKB/TrEMBL
SMART RICIN UniProtKB/TrEMBL
Superfamily-SCOP RicinB_like UniProtKB/TrEMBL
  SSF53448 UniProtKB/TrEMBL
UniProt Q3KR95 ENTREZGENE, UniProtKB/TrEMBL
  Q58A68 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-30 Galnt4  polypeptide N-acetylgalactosaminyltransferase 4  Galnt4  UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Galnt4  UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)  Galnt4  UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Galnt4  UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4  Galnt4  UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Galnt4  UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)      Symbol and Name status set to provisional 70820 PROVISIONAL