Gpr165 (G protein-coupled receptor 165) - Rat Genome Database

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Gene: Gpr165 (G protein-coupled receptor 165) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Gpr165
Name: G protein-coupled receptor 165
RGD ID: 1564566
Description: Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane; INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296866; RGD1564566; similar to G protein-coupled receptor 83
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X65,553,383 - 65,559,168 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX65,553,408 - 65,561,686 (+)EnsemblGRCr8
mRatBN7.2X61,543,906 - 61,549,691 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX61,543,906 - 61,549,691 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX63,004,007 - 63,009,789 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X66,504,549 - 66,510,331 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X64,067,864 - 64,073,644 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X65,796,359 - 65,802,144 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,796,429 - 65,804,591 (+)Ensemblrn6Rnor6.0
Rnor_5.0X66,627,493 - 66,633,278 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X84,285,430 - 84,291,215 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX61,952,227 - 61,958,012 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gpr165
28 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:584
Count of miRNA genes:246
Interacting mature miRNAs:297
Transcripts:ENSRNOT00000067298
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6103585667175160Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 11 43 142 37 36 9 9 9 5 134 81 6 120 28 84 27 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000067298   ⟹   ENSRNOP00000061124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX65,553,408 - 65,561,686 (+)Ensembl
mRatBN7.2 EnsemblX61,543,906 - 61,549,691 (+)Ensembl
Rnor_6.0 EnsemblX65,796,429 - 65,804,591 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076029   ⟹   ENSRNOP00000067962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX65,796,787 - 65,802,063 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076428   ⟹   ENSRNOP00000068295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX65,800,059 - 65,801,435 (+)Ensembl
RefSeq Acc Id: NM_001106582   ⟹   NP_001100052
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X65,553,383 - 65,559,168 (+)NCBI
mRatBN7.2X61,543,906 - 61,549,691 (+)NCBI
Rnor_6.0X65,796,359 - 65,802,144 (+)NCBI
Rnor_5.0X66,627,493 - 66,633,278 (+)NCBI
RGSC_v3.4X84,285,430 - 84,291,215 (+)RGD
CeleraX61,952,227 - 61,958,012 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100052 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL95965 (Get FASTA)   NCBI Sequence Viewer  
  EDL95966 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061124
  ENSRNOP00000061124.1
RefSeq Acc Id: NP_001100052   ⟸   NM_001106582
- UniProtKB: D4A9K0 (UniProtKB/TrEMBL),   A6IQ47 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061124   ⟸   ENSRNOT00000067298
Ensembl Acc Id: ENSRNOP00000067962   ⟸   ENSRNOT00000076029
Ensembl Acc Id: ENSRNOP00000068295   ⟸   ENSRNOT00000076428
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9K0-F1-model_v2 AlphaFold D4A9K0 1-462 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564566 AgrOrtholog
BioCyc Gene G2FUF-2179 BioCyc
Ensembl Genes ENSRNOG00000012995 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067298 ENTREZGENE
  ENSRNOT00000067298.5 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
KEGG Report rno:296866 UniProtKB/TrEMBL
NCBI Gene 296866 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  G-PROTEIN COUPLED RECEPTOR 165 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PhenoGen Gpr165 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012995 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6IQ47 ENTREZGENE, UniProtKB/TrEMBL
  D4A9K0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Gpr165  G protein-coupled receptor 165  RGD1564566_predicted  similar to G protein-coupled receptor 83 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564566_predicted  similar to G protein-coupled receptor 83 (predicted)  LOC296866  similar to G protein-coupled receptor 83  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC296866  similar to G protein-coupled receptor 83      Symbol and Name status set to provisional 70820 PROVISIONAL