Ugt3a1 (UDP glycosyltransferase family 3 member A1) - Rat Genome Database

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Gene: Ugt3a1 (UDP glycosyltransferase family 3 member A1) Rattus norvegicus
Analyze
Symbol: Ugt3a1
Name: UDP glycosyltransferase family 3 member A1
RGD ID: 1564365
Description: Predicted to enable glucuronosyltransferase activity. Predicted to act upstream of or within cellular response to genistein. Predicted to be located in membrane. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Orthologous to human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2); INTERACTS WITH bisphenol A; (1->4)-beta-D-glucan (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC294793; RGD1564365; similar to Hypothetical protein MGC37820; UDP glycosyltransferase 3 family, polypeptide A2; UDP glycosyltransferases 3 family, polypeptide A2; UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferase 3A2; Ugt3a2
RGD Orthologs
Human
Mouse
Bonobo
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8260,062,257 - 60,077,354 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl260,061,775 - 60,077,354 (+)EnsemblGRCr8
mRatBN7.2258,327,058 - 58,350,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl258,334,603 - 58,350,186 (+)EnsemblmRatBN7.2
Rnor_6.0258,666,337 - 58,682,212 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl258,668,157 - 58,681,747 (+)Ensemblrn6Rnor6.0
Rnor_5.0277,756,134 - 77,775,205 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4258,955,159 - 58,997,290 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera253,936,376 - 53,959,955 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22621930  


Genomics

Comparative Map Data
Ugt3a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8260,062,257 - 60,077,354 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl260,061,775 - 60,077,354 (+)EnsemblGRCr8
mRatBN7.2258,327,058 - 58,350,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl258,334,603 - 58,350,186 (+)EnsemblmRatBN7.2
Rnor_6.0258,666,337 - 58,682,212 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl258,668,157 - 58,681,747 (+)Ensemblrn6Rnor6.0
Rnor_5.0277,756,134 - 77,775,205 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4258,955,159 - 58,997,290 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera253,936,376 - 53,959,955 (+)NCBICelera
Cytogenetic Map2q16NCBI
UGT3A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38535,951,006 - 36,001,022 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl535,951,006 - 36,001,028 (-)Ensemblhg38GRCh38
GRCh37535,951,108 - 36,001,124 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36535,988,967 - 36,027,256 (-)NCBIBuild 36Build 36hg18NCBI36
Celera535,838,879 - 35,886,819 (-)NCBICelera
Cytogenetic Map5p13.2NCBI
HuRef535,903,464 - 35,951,406 (-)NCBIHuRef
CHM1_1535,955,886 - 36,003,836 (-)NCBICHM1_1
T2T-CHM13v2.0536,199,267 - 36,249,286 (-)NCBIT2T-CHM13v2.0
Ugt3a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,335,670 - 9,370,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,335,636 - 9,371,041 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38159,335,551 - 9,370,955 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,335,550 - 9,370,955 (+)Ensemblmm10GRCm38
MGSCv37159,265,353 - 9,300,625 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36159,267,771 - 9,315,584 (+)NCBIMGSCv36mm8
Celera159,136,088 - 9,171,085 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map154.01NCBI
UGT3A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2474,338,368 - 74,383,960 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1572,485,235 - 72,537,592 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0574,372,175 - 74,415,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1579,653,148 - 79,696,582 (+)NCBIPanPan1.1PanPan1.1panPan2
LOC103215128
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1434,799,857 - 34,841,195 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl434,795,751 - 34,839,803 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607125,120,691 - 25,161,211 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugt3a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475918,972,089 - 18,991,063 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ugt3a1
74 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:177
Count of miRNA genes:140
Interacting mature miRNAs:149
Transcripts:ENSRNOT00000033513, ENSRNOT00000074076
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6480225Gdil1Gastrointestinal dilation QTL 1enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)25838820177302351Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 12 6 23 23 21 7 21 48 20 6 6 8 2

Sequence


Ensembl Acc Id: ENSRNOT00000081192   ⟹   ENSRNOP00000073140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl260,061,775 - 60,077,354 (+)Ensembl
mRatBN7.2 Ensembl258,334,603 - 58,350,186 (+)Ensembl
Rnor_6.0 Ensembl258,668,157 - 58,681,747 (+)Ensembl
RefSeq Acc Id: XM_039103898   ⟹   XP_038959826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8260,062,257 - 60,077,354 (+)NCBI
mRatBN7.2258,327,058 - 58,350,186 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038959826 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073140
  ENSRNOP00000073140.2
Ensembl Acc Id: ENSRNOP00000073140   ⟸   ENSRNOT00000081192
RefSeq Acc Id: XP_038959826   ⟸   XM_039103898
- UniProtKB: A0A0G2K4R2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4R2-F1-model_v2 AlphaFold A0A0G2K4R2 1-424 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564365 AgrOrtholog
BioCyc Gene G2FUF-54100 BioCyc
Ensembl Genes ENSRNOG00000059568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081192 ENTREZGENE
  ENSRNOT00000081192.3 UniProtKB/TrEMBL
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/TrEMBL
InterPro UDP-glycosyltransferase UniProtKB/TrEMBL
  UDP_glucos_trans UniProtKB/TrEMBL
NCBI Gene 294793 ENTREZGENE
PANTHER EG:EG0003.4 PROTEIN-RELATED UniProtKB/TrEMBL
  UDP-GLUCURONOSYLTRANSFERASE 3A2 UniProtKB/TrEMBL
Pfam UDPGT UniProtKB/TrEMBL
PhenoGen Ugt3a1 PhenoGen
RatGTEx ENSRNOG00000059568 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/TrEMBL
UniProt A0A0G2K4R2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-12 Ugt3a1  UDP glycosyltransferase family 3 member A1  Ugt3a2  UDP glycosyltransferase 3 family, polypeptide A2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-07 Ugt3a2  UDP glycosyltransferase 3 family, polypeptide A2  Ugt3a2  UDP glycosyltransferases 3 family, polypeptide A2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Ugt3a2  UDP glycosyltransferases 3 family, polypeptide A2  RGD1564365_predicted  similar to Hypothetical protein MGC37820 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564365_predicted  similar to Hypothetical protein MGC37820 (predicted)  LOC294793  similar to Hypothetical protein MGC37820  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC294793  similar to Hypothetical protein MGC37820      Symbol and Name status set to provisional 70820 PROVISIONAL