Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nipal2 | Rat | 1,1-dichloroethene | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of NIPAL2 mRNA | CTD | PMID:26682919 | Nipal2 | Rat | 1,2-dichloroethane | increases expression | ISO | Nipal2 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of NIPAL2 mRNA | CTD | PMID:28960355 | Nipal2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of NIPAL2 mRNA | CTD | PMID:22206623 | Nipal2 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of NIPAL2 mRNA | CTD | PMID:25380136 | Nipal2 | Rat | 17beta-estradiol | affects expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Estradiol affects the expression of NIPAL2 mRNA | CTD | PMID:22574217 | Nipal2 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | increases expression | EXP | | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of NIPAL2 mRNA | CTD | PMID:20959002 | Nipal2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of NIPAL2 mRNA | CTD | PMID:31826744 | Nipal2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NIPAL2 mRNA | CTD | PMID:20959002|PMID:21215274|PMID:33387578 | Nipal2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of NIPAL2 mRNA | CTD | PMID:34747641 | Nipal2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NIPAL2 mRNA | CTD | PMID:21296121 | Nipal2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NIPAL2 mRNA | CTD | PMID:21354282 | Nipal2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nipal2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NIPAL2 mRNA | CTD | PMID:21570461 | Nipal2 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Nipal2 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of NIPAL2 mRNA | CTD | PMID:38648751 | Nipal2 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NIPAL2 mRNA | CTD | PMID:30851411 | Nipal2 | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NIPAL2 mRNA | CTD | PMID:20959002 | Nipal2 | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of NIPAL2 mRNA | CTD | PMID:25380136 | Nipal2 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Nipal2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of NIPAL2 mRNA | CTD | PMID:28973697 | Nipal2 | Rat | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of NIPAL2 mRNA | CTD | PMID:31881176 | Nipal2 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of NIPAL2 mRNA | CTD | PMID:28959563 | Nipal2 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of NIPAL2 mRNA | CTD | PMID:23630614|PMID:25378103 | Nipal2 | Rat | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of NIPAL2 mRNA | CTD | PMID:30779732 | Nipal2 | Rat | aristolochic acid A | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NIPAL2 mRNA | CTD | PMID:33212167 | Nipal2 | Rat | belinostat | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | belinostat results in decreased expression of NIPAL2 mRNA | CTD | PMID:27188386 | Nipal2 | Rat | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | benzo[a]pyrene | decreases methylation | ISO | NIPAL2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of NIPAL2 promoter | CTD | PMID:27901495 | Nipal2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of NIPAL2 mRNA | CTD | PMID:20382639 | Nipal2 | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of NIPAL2 mRNA | CTD | PMID:26377693 | Nipal2 | Rat | bisphenol A | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NIPAL2 mRNA | CTD | PMID:26063408 | Nipal2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NIPAL2 mRNA | CTD | PMID:32145629 | Nipal2 | Rat | bisphenol A | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of NIPAL2 mRNA | CTD | PMID:31715268 | Nipal2 | Rat | calcitriol | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of NIPAL2 mRNA | CTD | PMID:16002434 | Nipal2 | Rat | carbon nanotube | increases expression | ISO | Nipal2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of NIPAL2 mRNA | CTD | PMID:25554681 | Nipal2 | Rat | cisplatin | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of NIPAL2 mRNA | CTD | PMID:27392435 | Nipal2 | Rat | cisplatin | multiple interactions | ISO | NIPAL2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of NIPAL2 mRNA | CTD | PMID:27392435 | Nipal2 | Rat | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of NIPAL2 mRNA | CTD | PMID:21266533 | Nipal2 | Rat | dorsomorphin | multiple interactions | ISO | NIPAL2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Nipal2 | Rat | doxorubicin | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NIPAL2 mRNA | CTD | PMID:29803840 | Nipal2 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of NIPAL2 mRNA | CTD | PMID:25539665|PMID:27387713 | Nipal2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of NIPAL2 mRNA | CTD | PMID:33387578 | Nipal2 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of NIPAL2 mRNA | CTD | PMID:21396975 | Nipal2 | Rat | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NIPAL2 mRNA | CTD | PMID:22129741 | Nipal2 | Rat | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | mercury dibromide | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of NIPAL2 mRNA | CTD | PMID:26272509 | Nipal2 | Rat | mercury dibromide | multiple interactions | ISO | NIPAL2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Nipal2 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of NIPAL2 gene | CTD | PMID:35440735 | Nipal2 | Rat | Moniliformin | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | moniliformin results in decreased expression of NIPAL2 mRNA | CTD | PMID:39984025 | Nipal2 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of NIPAL2 gene | CTD | PMID:33148267 | Nipal2 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NIPAL2 mRNA | CTD | PMID:22129741 | Nipal2 | Rat | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of NIPAL2 mRNA | CTD | PMID:23665939 | Nipal2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of NIPAL2 mRNA | CTD | PMID:25729387 | Nipal2 | Rat | panobinostat | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | panobinostat results in increased expression of NIPAL2 mRNA | CTD | PMID:26272509 | Nipal2 | Rat | panobinostat | multiple interactions | ISO | NIPAL2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Nipal2 | Rat | paracetamol | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NIPAL2 mRNA | CTD | PMID:21420995 | Nipal2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NIPAL2 mRNA | CTD | PMID:33387578 | Nipal2 | Rat | paracetamol | multiple interactions | ISO | Nipal2 (Mus musculus) | 6480464 | MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of NIPAL2 mRNA] | CTD | PMID:18700144 | Nipal2 | Rat | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of NIPAL2 mRNA | CTD | PMID:19162173 | Nipal2 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of NIPAL2 gene | CTD | PMID:33148267 | Nipal2 | Rat | phenylmercury acetate | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of NIPAL2 mRNA | CTD | PMID:26272509 | Nipal2 | Rat | phenylmercury acetate | multiple interactions | ISO | NIPAL2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Nipal2 | Rat | pirinixic acid | increases expression | ISO | Nipal2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NIPAL2 mRNA | CTD | PMID:20813756 | Nipal2 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of NIPAL2 mRNA | CTD | PMID:19162173|PMID:22484513 | Nipal2 | Rat | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | potassium dichromate | increases expression | ISO | Nipal2 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of NIPAL2 mRNA | CTD | PMID:23608068 | Nipal2 | Rat | rac-lactic acid | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NIPAL2 mRNA | CTD | PMID:30851411 | Nipal2 | Rat | SB 431542 | multiple interactions | ISO | NIPAL2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Nipal2 | Rat | silicon dioxide | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of NIPAL2 mRNA | CTD | PMID:25351596 | Nipal2 | Rat | sodium arsenite | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of NIPAL2 mRNA | CTD | PMID:38568856 | Nipal2 | Rat | sodium arsenite | decreases expression | ISO | Nipal2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NIPAL2 mRNA | CTD | PMID:37682722 | Nipal2 | Rat | sodium arsenite | decreases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NIPAL2 mRNA | CTD | PMID:34032870 | Nipal2 | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of NIPAL2 mRNA | CTD | PMID:19483382 | Nipal2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NIPAL2 mRNA | CTD | PMID:23411599 | Nipal2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of NIPAL2 mRNA | CTD | PMID:25729387 | Nipal2 | Rat | tributylstannane | increases expression | EXP | | 6480464 | tributyltin results in increased expression of NIPAL2 mRNA | CTD | PMID:21683754 | Nipal2 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of NIPAL2 mRNA | CTD | PMID:33387578 | Nipal2 | Rat | trichostatin A | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of NIPAL2 mRNA | CTD | PMID:24935251 | Nipal2 | Rat | valproic acid | decreases methylation | ISO | NIPAL2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NIPAL2 gene | CTD | PMID:29154799 | Nipal2 | Rat | valproic acid | increases expression | ISO | NIPAL2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NIPAL2 mRNA | CTD | PMID:28001369 | Nipal2 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of NIPAL2 mRNA | CTD | PMID:19015723 | Nipal2 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of NIPAL2 mRNA | CTD | PMID:23034163 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















