Gpr101 (G protein-coupled receptor 101) - Rat Genome Database

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Gene: Gpr101 (G protein-coupled receptor 101) Rattus norvegicus
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Symbol: Gpr101
Name: G protein-coupled receptor 101
RGD ID: 1564196
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and positive regulation of MAPK cascade. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in growth hormone secreting pituitary adenoma 2. Orthologous to human GPR101 (G protein-coupled receptor 101); INTERACTS WITH acrylamide; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC317608; probable G-protein coupled receptor 101; RGD1564196; similar to G protein-coupled receptor 101
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X140,575,818 - 140,579,734 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX140,572,068 - 140,580,369 (-)EnsemblGRCr8
mRatBN7.2X135,540,042 - 135,543,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX135,540,042 - 135,543,958 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX137,735,393 - 137,739,309 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X141,290,573 - 141,294,489 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X138,860,204 - 138,864,120 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X140,296,220 - 140,303,743 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX140,299,770 - 140,303,686 (-)Ensemblrn6Rnor6.0
Rnor_5.0X140,345,513 - 140,350,282 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X142,532,629 - 142,536,545 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX131,694,130 - 131,698,046 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18187126   PMID:23382219  


Genomics

Comparative Map Data
Gpr101
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X140,575,818 - 140,579,734 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX140,572,068 - 140,580,369 (-)EnsemblGRCr8
mRatBN7.2X135,540,042 - 135,543,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX135,540,042 - 135,543,958 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX137,735,393 - 137,739,309 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X141,290,573 - 141,294,489 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X138,860,204 - 138,864,120 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X140,296,220 - 140,303,743 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX140,299,770 - 140,303,686 (-)Ensemblrn6Rnor6.0
Rnor_5.0X140,345,513 - 140,350,282 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X142,532,629 - 142,536,545 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX131,694,130 - 131,698,046 (-)NCBICelera
Cytogenetic MapXq36NCBI
GPR101
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X137,023,929 - 137,033,995 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX137,023,929 - 137,033,995 (-)Ensemblhg38GRCh38
GRCh37X136,106,088 - 136,116,154 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X135,939,973 - 135,941,499 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X135,837,826 - 135,839,353NCBI
CeleraX136,476,405 - 136,477,931 (-)NCBICelera
Cytogenetic MapXq26.3NCBI
HuRefX125,379,125 - 125,380,651 (-)NCBIHuRef
CHM1_1X136,024,015 - 136,025,541 (-)NCBICHM1_1
T2T-CHM13v2.0X135,332,378 - 135,342,444 (-)NCBIT2T-CHM13v2.0
Gpr101
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X56,542,028 - 56,549,117 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX56,542,028 - 56,549,117 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X57,496,668 - 57,503,757 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX57,496,668 - 57,503,757 (-)Ensemblmm10GRCm38
MGSCv37X54,749,845 - 54,756,934 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X53,846,588 - 53,850,485 (-)NCBIMGSCv36mm8
CeleraX43,973,533 - 43,980,649 (-)NCBICelera
Cytogenetic MapXA6NCBI
cM MapX31.93NCBI
Gpr101
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554898,125,763 - 8,127,280 (+)Ensembl
ChiLan1.0NW_0049554898,125,763 - 8,127,280 (+)NCBIChiLan1.0ChiLan1.0
GPR101
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X136,442,598 - 136,452,639 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X136,446,200 - 136,456,239 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X126,149,803 - 126,159,844 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X136,418,522 - 136,420,048 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX136,418,522 - 136,420,048 (-)EnsemblpanPan2panpan1.1
GPR101
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X107,302,200 - 107,304,733 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX107,303,175 - 107,304,689 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX93,130,700 - 93,132,214 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X109,282,734 - 109,284,248 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX109,281,757 - 109,286,423 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X106,422,687 - 106,424,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X108,614,254 - 108,615,768 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X108,257,035 - 108,258,549 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gpr101
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X105,324,248 - 105,334,178 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651310,282,683 - 10,284,206 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651310,282,683 - 10,284,206 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR101
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX112,108,889 - 112,113,652 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X112,109,592 - 112,111,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GPR101
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X112,057,904 - 112,063,298 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX112,058,791 - 112,060,323 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606549,755,493 - 49,759,703 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr101
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248089,951,202 - 9,953,971 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248089,950,331 - 9,960,019 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Gpr101
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X39,210,379 - 39,214,569 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gpr101
12 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:203
Count of miRNA genes:149
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000033219
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X120028026141353710Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X120028026141353710Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
100 5 2 1 99 1 26 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000033219   ⟹   ENSRNOP00000029809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX140,572,068 - 140,580,040 (-)Ensembl
mRatBN7.2 EnsemblX135,540,042 - 135,543,958 (-)Ensembl
Rnor_6.0 EnsemblX140,299,770 - 140,303,686 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155568   ⟹   ENSRNOP00000100263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX140,572,264 - 140,580,369 (-)Ensembl
RefSeq Acc Id: NM_001108258   ⟹   NP_001101728
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X140,575,818 - 140,579,734 (-)NCBI
mRatBN7.2X135,540,042 - 135,543,958 (-)NCBI
Rnor_6.0X140,299,770 - 140,303,686 (-)NCBI
Rnor_5.0X140,345,513 - 140,350,282 (-)NCBI
RGSC_v3.4X142,532,629 - 142,536,545 (-)RGD
CeleraX131,694,130 - 131,698,046 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101728 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86156 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000029809
  ENSRNOP00000029809.4
  ENSRNOP00000100263.1
RefSeq Acc Id: NP_001101728   ⟸   NM_001108258
- UniProtKB: D4ABK4 (UniProtKB/TrEMBL),   A6K4Y8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029809   ⟸   ENSRNOT00000033219
Ensembl Acc Id: ENSRNOP00000100263   ⟸   ENSRNOT00000155568
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ABK4-F1-model_v2 AlphaFold D4ABK4 1-508 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564196 AgrOrtholog
BioCyc Gene G2FUF-900 BioCyc
Ensembl Genes ENSRNOG00000027658 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033219 ENTREZGENE
  ENSRNOT00000033219.6 UniProtKB/TrEMBL
  ENSRNOT00000155568.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
KEGG Report rno:317608 UniProtKB/TrEMBL
NCBI Gene 317608 ENTREZGENE
PANTHER G PROTEIN-COUPLED RECEPTOR UniProtKB/TrEMBL
  G-PROTEIN COUPLED RECEPTOR 101-RELATED UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PhenoGen Gpr101 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027658 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6K4Y8 ENTREZGENE, UniProtKB/TrEMBL
  D4ABK4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Gpr101  G protein-coupled receptor 101   Gpr101_predicted  G protein-coupled receptor 101 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Gpr101_predicted  G protein-coupled receptor 101 (predicted)  RGD1564196_predicted  similar to G protein-coupled receptor 101 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1564196_predicted  similar to G protein-coupled receptor 101 (predicted)  LOC317608  similar to G protein-coupled receptor 101  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317608  similar to G protein-coupled receptor 101      Symbol and Name status set to provisional 70820 PROVISIONAL