Tns3 (tensin 3) - Rat Genome Database

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Gene: Tns3 (tensin 3) Rattus norvegicus
Analyze
Symbol: Tns3
Name: tensin 3
RGD ID: 1564174
Description: Predicted to enable metal ion binding activity and phosphoprotein phosphatase activity. Predicted to be involved in positive regulation of Rac protein signal transduction. Predicted to act upstream of or within several processes, including bone resorption; negative regulation of Rho protein signal transduction; and podosome assembly. Predicted to be located in podosome. Predicted to be active in focal adhesion. Orthologous to human TNS3 (tensin 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360980; LOC498410; RGD1564174; similar to novel protein similar to Tensin Tns; tensin-3; tensin3; TSN3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81487,387,441 - 87,619,457 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1487,387,441 - 87,619,712 (-)EnsemblGRCr8
mRatBN7.21483,173,649 - 83,405,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,173,649 - 83,405,998 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1487,562,787 - 87,733,800 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01488,802,650 - 88,973,675 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01485,270,263 - 85,440,878 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01488,673,922 - 88,907,874 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1488,673,881 - 88,886,198 (-)Ensemblrn6Rnor6.0
Rnor_5.01488,471,109 - 88,707,006 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41488,999,003 - 89,182,348 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1482,216,888 - 82,385,811 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butan-1-ol  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
coumarin  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
diuron  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
lead(0)  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triacsin C  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell projection  (IEA)
focal adhesion  (IBA,IEA,ISO)
podosome  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:12947022   PMID:15140944   PMID:15733665   PMID:21423176  


Genomics

Comparative Map Data
Tns3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81487,387,441 - 87,619,457 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1487,387,441 - 87,619,712 (-)EnsemblGRCr8
mRatBN7.21483,173,649 - 83,405,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,173,649 - 83,405,998 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1487,562,787 - 87,733,800 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01488,802,650 - 88,973,675 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01485,270,263 - 85,440,878 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01488,673,922 - 88,907,874 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1488,673,881 - 88,886,198 (-)Ensemblrn6Rnor6.0
Rnor_5.01488,471,109 - 88,707,006 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41488,999,003 - 89,182,348 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1482,216,888 - 82,385,811 (-)NCBICelera
Cytogenetic Map14q21NCBI
TNS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38747,275,154 - 47,582,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl747,275,154 - 47,582,558 (-)Ensemblhg38GRCh38
GRCh37747,314,752 - 47,622,184 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36747,281,277 - 47,545,724 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34747,087,993 - 47,224,622NCBI
Celera747,415,102 - 47,679,562 (-)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef747,288,963 - 47,506,850 (-)NCBIHuRef
HuRef747,200,591 - 47,271,824 (-)NCBIHuRef
CHM1_1747,317,875 - 47,625,490 (-)NCBICHM1_1
T2T-CHM13v2.0747,436,453 - 47,744,868 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2747,354,555 - 47,661,993 (-)NCBI
Tns3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39118,381,652 - 8,614,758 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl118,381,652 - 8,614,681 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38118,431,652 - 8,664,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl118,431,652 - 8,664,681 (-)Ensemblmm10GRCm38
MGSCv37118,331,655 - 8,564,538 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36118,331,655 - 8,564,667 (-)NCBIMGSCv36mm8
Celera118,889,366 - 9,121,641 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.99NCBI
Tns3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554565,717,142 - 5,812,291 (+)Ensembl
ChiLan1.0NW_0049554565,671,688 - 5,812,039 (+)NCBIChiLan1.0ChiLan1.0
TNS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2652,149,624 - 52,457,354 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17100,474,361 - 100,782,091 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0747,915,668 - 48,223,267 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1748,025,720 - 48,333,780 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl748,025,720 - 48,221,437 (-)EnsemblpanPan2panpan1.1
TNS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.116279,468 - 432,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl16278,957 - 431,704 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha161,052,090 - 1,207,662 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.016261,024 - 417,278 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl16259,747 - 417,245 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.116252,349 - 408,320 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.016199,965 - 344,181 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.016830,727 - 909,142 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tns3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118102,573,624 - 102,712,527 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647821,786,120 - 21,924,221 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647821,784,486 - 21,924,240 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,997,217 - 49,192,433 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11848,960,938 - 49,192,434 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,753,535 - 53,889,976 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12111,248,003 - 11,554,903 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2111,292,788 - 11,554,933 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236661317,067 - 198,637 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tns3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247405,824,510 - 5,930,478 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247405,776,883 - 5,928,434 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tns3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11177,543,250 - 77,673,969 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tns3
1827 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:335
Count of miRNA genes:203
Interacting mature miRNAs:251
Transcripts:ENSRNOT00000012661
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
RH143114  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21483,292,626 - 83,292,820 (+)MAPPERmRatBN7.2
Rnor_6.01488,795,180 - 88,795,373NCBIRnor6.0
Rnor_5.01488,594,149 - 88,594,342UniSTSRnor5.0
RGSC_v3.41489,116,282 - 89,116,475UniSTSRGSC3.4
Celera1482,333,937 - 82,334,130UniSTS
RH 3.4 Map14616.9UniSTS
Cytogenetic Map14q21UniSTS
RH139945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21483,175,672 - 83,175,878 (+)MAPPERmRatBN7.2
Rnor_6.01488,675,946 - 88,676,151NCBIRnor6.0
Rnor_5.01488,473,133 - 88,473,338UniSTSRnor5.0
RGSC_v3.41489,001,027 - 89,001,232UniSTSRGSC3.4
Celera1482,218,912 - 82,219,117UniSTS
RH 3.4 Map14608.4UniSTS
Cytogenetic Map14q21UniSTS
AA891734  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21483,174,103 - 83,174,294 (+)MAPPERmRatBN7.2
Rnor_6.01488,674,377 - 88,674,567NCBIRnor6.0
Rnor_5.01488,471,564 - 88,471,754UniSTSRnor5.0
RGSC_v3.41488,999,458 - 88,999,648UniSTSRGSC3.4
Celera1482,217,343 - 82,217,533UniSTS
RH 3.4 Map14635.09UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001170459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB510354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC160892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF555576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI303719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF110833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK478259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO384022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO556724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM131608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000012661   ⟹   ENSRNOP00000012661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,619,441 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,405,998 (-)Ensembl
Rnor_6.0 Ensembl1488,673,881 - 88,886,198 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095500   ⟹   ENSRNOP00000092700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,558,772 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,332,690 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100195   ⟹   ENSRNOP00000084226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,571,876 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,358,192 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100927   ⟹   ENSRNOP00000092570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,515,703 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,306,106 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108654   ⟹   ENSRNOP00000086044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,619,712 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,405,998 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110382   ⟹   ENSRNOP00000089828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,579,393 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,365,698 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115367   ⟹   ENSRNOP00000081446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,619,441 (-)Ensembl
mRatBN7.2 Ensembl1483,173,649 - 83,405,998 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000153659   ⟹   ENSRNOP00000110716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,597,094 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155100   ⟹   ENSRNOP00000104075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,618,927 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000173768   ⟹   ENSRNOP00000108233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1487,387,441 - 87,590,394 (-)Ensembl
RefSeq Acc Id: NM_001170459   ⟹   NP_001163930
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,619,386 (-)NCBI
mRatBN7.21483,173,649 - 83,405,605 (-)NCBI
Rnor_6.01488,673,922 - 88,846,871 (-)NCBI
Rnor_5.01488,471,109 - 88,707,006 (-)NCBI
Celera1482,216,888 - 82,385,811 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251460   ⟹   XP_006251522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,619,457 (-)NCBI
mRatBN7.21483,173,649 - 83,405,671 (-)NCBI
Rnor_6.01488,673,922 - 88,907,874 (-)NCBI
Rnor_5.01488,471,109 - 88,707,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251462   ⟹   XP_006251524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,579,680 (-)NCBI
mRatBN7.21483,173,649 - 83,365,923 (-)NCBI
Rnor_6.01488,673,922 - 88,868,663 (-)NCBI
Rnor_5.01488,471,109 - 88,707,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251467   ⟹   XP_006251529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,618,832 (-)NCBI
mRatBN7.21483,173,649 - 83,405,381 (-)NCBI
Rnor_6.01488,673,922 - 88,907,352 (-)NCBI
Rnor_5.01488,471,109 - 88,707,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770335   ⟹   XP_008768557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,618,957 (-)NCBI
mRatBN7.21483,173,649 - 83,405,381 (-)NCBI
Rnor_6.01488,673,922 - 88,907,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770336   ⟹   XP_008768558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,516,870 (-)NCBI
mRatBN7.21483,173,649 - 83,302,912 (-)NCBI
Rnor_6.01488,673,922 - 88,805,507 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092228   ⟹   XP_038948156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,461,148 (-)NCBI
mRatBN7.21483,173,649 - 83,247,384 (-)NCBI
RefSeq Acc Id: XM_039092229   ⟹   XP_038948157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,457,961 (-)NCBI
mRatBN7.21483,173,649 - 83,244,172 (-)NCBI
RefSeq Acc Id: XM_063273400   ⟹   XP_063129470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,619,397 (-)NCBI
RefSeq Acc Id: XM_063273401   ⟹   XP_063129471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,618,957 (-)NCBI
RefSeq Acc Id: XM_063273403   ⟹   XP_063129473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,578,528 (-)NCBI
RefSeq Acc Id: XM_063273404   ⟹   XP_063129474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81487,387,441 - 87,612,638 (-)NCBI
RefSeq Acc Id: NP_001163930   ⟸   NM_001170459
- UniProtKB: C5NTX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251522   ⟸   XM_006251460
- Peptide Label: isoform X1
- UniProtKB: C5NTX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251529   ⟸   XM_006251467
- Peptide Label: isoform X6
- UniProtKB: C5NTX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251524   ⟸   XM_006251462
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ADB6 (UniProtKB/TrEMBL),   A0A8I6A0U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768557   ⟸   XM_008770335
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZST1 (UniProtKB/TrEMBL),   A0A8I6A0U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768558   ⟸   XM_008770336
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AHA2 (UniProtKB/TrEMBL),   A0A8I6AI66 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012661   ⟸   ENSRNOT00000012661
RefSeq Acc Id: XP_038948156   ⟸   XM_039092228
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038948157   ⟸   XM_039092229
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000081446   ⟸   ENSRNOT00000115367
Ensembl Acc Id: ENSRNOP00000084226   ⟸   ENSRNOT00000100195
Ensembl Acc Id: ENSRNOP00000092700   ⟸   ENSRNOT00000095500
Ensembl Acc Id: ENSRNOP00000092570   ⟸   ENSRNOT00000100927
Ensembl Acc Id: ENSRNOP00000089828   ⟸   ENSRNOT00000110382
Ensembl Acc Id: ENSRNOP00000086044   ⟸   ENSRNOT00000108654
RefSeq Acc Id: XP_063129470   ⟸   XM_063273400
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZST1 (UniProtKB/TrEMBL),   A0A8I6A0U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129471   ⟸   XM_063273401
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A0U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129474   ⟸   XM_063273404
- Peptide Label: isoform X6
- UniProtKB: C5NTX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129473   ⟸   XM_063273403
- Peptide Label: isoform X6
- UniProtKB: C5NTX8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110716   ⟸   ENSRNOT00000153659
Ensembl Acc Id: ENSRNOP00000104075   ⟸   ENSRNOT00000155100
Ensembl Acc Id: ENSRNOP00000108233   ⟸   ENSRNOT00000173768
Protein Domains
C2 tensin-type   Phorbol-ester/DAG-type   Phosphatase tensin-type   SH2   Tyrosine specific protein phosphatases

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LN91-F1-model_v2 AlphaFold F1LN91 1-1526 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564174 AgrOrtholog
BioCyc Gene G2FUF-15033 BioCyc
Ensembl Genes ENSRNOG00000025695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012661.9 UniProtKB/TrEMBL
  ENSRNOT00000095500 ENTREZGENE
  ENSRNOT00000095500.2 UniProtKB/TrEMBL
  ENSRNOT00000100195.2 UniProtKB/TrEMBL
  ENSRNOT00000100927 ENTREZGENE
  ENSRNOT00000100927.2 UniProtKB/TrEMBL
  ENSRNOT00000108654 ENTREZGENE
  ENSRNOT00000108654.2 UniProtKB/TrEMBL
  ENSRNOT00000110382 ENTREZGENE
  ENSRNOT00000110382.2 UniProtKB/TrEMBL
  ENSRNOT00000115367 ENTREZGENE
  ENSRNOT00000115367.2 UniProtKB/TrEMBL
  ENSRNOT00000153659.1 UniProtKB/TrEMBL
  ENSRNOT00000155100 ENTREZGENE
  ENSRNOT00000155100.1 UniProtKB/TrEMBL
  ENSRNOT00000173768.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.1110 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7443268 IMAGE-MGC_LOAD
InterPro C1-like_sf UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTB UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  Tensin_like_SH2 UniProtKB/TrEMBL
  Tensin_lipid_phosphatase_dom UniProtKB/TrEMBL
  Tensin_phosphatase_C2-dom UniProtKB/TrEMBL
  Tensin_PTB UniProtKB/TrEMBL
  Tensin_PTEN_phosphatase UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
MGC_CLONE MGC:188320 IMAGE-MGC_LOAD
NCBI Gene 360980 ENTREZGENE
PANTHER TENSIN UniProtKB/TrEMBL
  TENSIN-3 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  PTB UniProtKB/TrEMBL
  PTEN_C2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PhenoGen Tns3 PhenoGen
PROSITE C2_TENSIN UniProtKB/TrEMBL
  PPASE_TENSIN UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025695 RatGTEx
SMART PTB UniProtKB/TrEMBL
  PTEN_C2 UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A8I5ZST1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0U4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A502_RAT UniProtKB/TrEMBL
  A0A8I6ADB6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AI66 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LF62_RAT UniProtKB/TrEMBL
  A0ABK0LIJ9_RAT UniProtKB/TrEMBL
  A0ABK0LTN4_RAT UniProtKB/TrEMBL
  C5NTX8 ENTREZGENE, UniProtKB/TrEMBL
  F1LN91_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 RGD1564174  similar to novel protein similar to Tensin Tns   RGD1564174_predicted  similar to novel protein similar to Tensin Tns (predicted)  'predicted' is removed 2292626 APPROVED
2008-01-09 RGD1564174_predicted  similar to novel protein similar to Tensin Tns (predicted)  RGD1564930_predicted  similar to novel protein similar to Tensin Tns (predicted)  Data merged from RGD:1564930 1643240 APPROVED
2006-03-07 RGD1564174_predicted  similar to novel protein similar to Tensin Tns (predicted)  LOC360980  similar to novel protein similar to Tensin Tns  Symbol and Name status set to approved 1299863 APPROVED
2006-03-07 RGD1564930_predicted  similar to novel protein similar to Tensin Tns (predicted)  LOC498410  similar to novel protein similar to Tensin Tns  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC360980  similar to novel protein similar to Tensin Tns      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC498410  similar to novel protein similar to Tensin Tns      Symbol and Name status set to provisional 70820 PROVISIONAL