Wdr83os (WD repeat domain 83 opposite strand) - Rat Genome Database

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Gene: Wdr83os (WD repeat domain 83 opposite strand) Rattus norvegicus
Analyze
Symbol: Wdr83os
Name: WD repeat domain 83 opposite strand
RGD ID: 1564058
Description: Orthologous to human WDR83OS (WD repeat domain 83 opposite strand); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC288925; LOC288925; PAT complex subunit Asterix; protein Asterix; RGD1564058; similar to cDNA sequence BC056474; uncharacterized protein LOC288925
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81939,980,247 - 39,981,619 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1939,980,247 - 39,982,737 (-)EnsemblGRCr8
mRatBN7.21923,075,373 - 23,076,745 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,075,376 - 23,076,894 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1929,897,990 - 29,899,362 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,552,354 - 30,553,726 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,775,035 - 32,776,407 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01926,194,336 - 26,195,837 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,194,465 - 26,195,837 (+)Ensemblrn6Rnor6.0
Rnor_5.01937,169,964 - 37,171,460 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41924,731,659 - 24,733,024 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1922,633,343 - 22,634,708 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Wdr83os
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81939,980,247 - 39,981,619 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1939,980,247 - 39,982,737 (-)EnsemblGRCr8
mRatBN7.21923,075,373 - 23,076,745 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,075,376 - 23,076,894 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1929,897,990 - 29,899,362 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,552,354 - 30,553,726 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,775,035 - 32,776,407 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01926,194,336 - 26,195,837 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,194,465 - 26,195,837 (+)Ensemblrn6Rnor6.0
Rnor_5.01937,169,964 - 37,171,460 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41924,731,659 - 24,733,024 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1922,633,343 - 22,634,708 (-)NCBICelera
Cytogenetic Map19q11NCBI
WDR83OS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,668,073 - 12,669,415 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,668,073 - 12,669,430 (-)Ensemblhg38GRCh38
GRCh371912,778,887 - 12,780,229 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,639,887 - 12,641,449 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1912,668,595 - 12,670,179 (-)NCBICelera
Cytogenetic Map19p13.13NCBI
HuRef1912,351,969 - 12,353,553 (-)NCBIHuRef
CHM1_11912,779,386 - 12,780,970 (-)NCBICHM1_1
T2T-CHM13v2.01912,792,571 - 12,793,913 (-)NCBIT2T-CHM13v2.0
Wdr83os
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,807,592 - 85,808,968 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl885,807,369 - 85,808,968 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38885,080,963 - 85,082,339 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,080,740 - 85,082,339 (+)Ensemblmm10GRCm38
MGSCv37887,604,862 - 87,606,238 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36887,971,068 - 87,972,444 (+)NCBIMGSCv36mm8
Celera889,375,429 - 89,376,803 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.55NCBI
Wdr83os
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,772,401 - 31,773,916 (-)Ensembl
ChiLan1.0NW_00495541531,772,401 - 31,773,916 (-)NCBIChiLan1.0ChiLan1.0
WDR83OS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22017,596,982 - 17,598,402 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11916,597,559 - 16,598,979 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01912,230,204 - 12,231,881 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11912,975,314 - 12,976,896 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1912,975,314 - 12,976,896 (-)EnsemblpanPan2panpan1.1
WDR83OS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,443,893 - 49,445,342 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,443,951 - 49,445,330 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2049,317,346 - 49,318,922 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02049,962,443 - 49,964,019 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,962,635 - 49,964,014 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12049,173,239 - 49,174,814 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,599,980 - 49,601,556 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,842,292 - 49,843,868 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wdr83os
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,558,842 - 208,560,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,794,432 - 1,795,788 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,794,430 - 1,795,811 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR83OS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,325,992 - 66,328,004 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1266,312,920 - 66,328,000 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,692,103 - 66,705,732 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR83OS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,356,542 - 11,358,109 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,356,544 - 11,357,884 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660748,439,378 - 8,440,952 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr83os
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624901309,058 - 310,686 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624901309,058 - 310,663 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Wdr83os
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11715,210,051 - 15,211,604 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wdr83os
7 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:95
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000065931
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
MARC_7999-8000:996688236:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81939,980,566 - 39,981,329 (+)Marker Load Pipeline
mRatBN7.21923,075,692 - 23,076,455 (-)MAPPERmRatBN7.2
Rnor_6.01926,194,754 - 26,195,516NCBIRnor6.0
Rnor_5.01937,170,377 - 37,171,139UniSTSRnor5.0
RGSC_v3.41924,731,980 - 24,732,742UniSTSRGSC3.4
Celera1922,633,664 - 22,634,426UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000065931   ⟹   ENSRNOP00000063158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1926,194,472 - 26,195,837 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087627   ⟹   ENSRNOP00000070833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1939,980,247 - 39,981,619 (-)Ensembl
mRatBN7.2 Ensembl1923,075,376 - 23,076,894 (+)Ensembl
Rnor_6.0 Ensembl1926,194,465 - 26,195,835 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158835   ⟹   ENSRNOP00000104626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1939,980,247 - 39,982,737 (-)Ensembl
RefSeq Acc Id: NM_001105947   ⟹   NP_001099417
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,980,247 - 39,981,619 (-)NCBI
mRatBN7.21923,075,373 - 23,076,745 (-)NCBI
Rnor_6.01926,194,472 - 26,195,837 (+)NCBI
Rnor_5.01937,169,964 - 37,171,460 (+)NCBI
RGSC_v3.41924,731,659 - 24,733,024 (-)RGD
Celera1922,633,343 - 22,634,708 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399208   ⟹   NP_001386137
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,980,247 - 39,981,619 (-)NCBI
mRatBN7.21923,075,373 - 23,076,745 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001099417 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386137 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66543 (Get FASTA)   NCBI Sequence Viewer  
  EDL92153 (Get FASTA)   NCBI Sequence Viewer  
  EDL92154 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000104626.1
  ENSRNOP00000108742
  ENSRNOP00000108742.1
RefSeq Acc Id: NP_001099417   ⟸   NM_001105947
- Peptide Label: isoform 2
- UniProtKB: A6IY25 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070833   ⟸   ENSRNOT00000087627
Ensembl Acc Id: ENSRNOP00000063158   ⟸   ENSRNOT00000065931
RefSeq Acc Id: NP_001386137   ⟸   NM_001399208
- Peptide Label: isoform 1
- UniProtKB: B2GV64 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104626   ⟸   ENSRNOT00000158835

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYI4-F1-model_v2 AlphaFold D3ZYI4 1-117 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701042
Promoter ID:EPDNEW_R11565
Type:initiation region
Name:Wdr83os_1
Description:WD repeat domain 83 opposite strand
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01926,194,478 - 26,194,538EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564058 AgrOrtholog
BioCyc Gene G2FUF-6148 BioCyc
Ensembl Genes ENSRNOG00000033611 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000087627 ENTREZGENE
  ENSRNOT00000087627.3 UniProtKB/TrEMBL
  ENSRNOT00000158835.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7300989 IMAGE-MGC_LOAD
InterPro UPF0139 UniProtKB/TrEMBL
KEGG Report rno:288925 UniProtKB/TrEMBL
MGC_CLONE MGC:188141 IMAGE-MGC_LOAD
NCBI Gene 288925 ENTREZGENE
PANTHER PAT COMPLEX SUBUNIT ASTERIX UniProtKB/TrEMBL
  UPF0139 UniProtKB/TrEMBL
Pfam UPF0139 UniProtKB/TrEMBL
PhenoGen Wdr83os PhenoGen
RatGTEx ENSRNOG00000033611 RatGTEx
RNAcentral URS00022B026E RNACentral
UniProt A0ABK0LSP7_RAT UniProtKB/TrEMBL
  A0ABK0M2E3_RAT UniProtKB/TrEMBL
  A6IY25 ENTREZGENE, UniProtKB/TrEMBL
  B2GV64 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-06 Wdr83os  WD repeat domain 83 opposite strand  RGD1564058  similar to cDNA sequence BC056474  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1564058  similar to cDNA sequence BC056474   RGD1564058_predicted  similar to cDNA sequence BC056474 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564058_predicted  similar to cDNA sequence BC056474 (predicted)  LOC288925  similar to cDNA sequence BC056474  Symbol and Name status set to approved 1299863 APPROVED