Advanced Search (OLGA)

Gene: Scube2 (signal peptide, CUB domain and EGF like domain containing 2) Rattus norvegicus

Analyze

Symbol:

Scube2

Name:

signal peptide, CUB domain and EGF like domain containing 2

RGD ID:

1563998

Description:

Predicted to enable hedgehog family protein binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within several processes, including chondrocyte differentiation involved in endochondral bone morphogenesis; positive regulation of chondrocyte proliferation; and positive regulation of osteoblast differentiation. Predicted to be located in extracellular region. Predicted to be active in cell surface and extracellular space. Orthologous to human SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; dimethylarsinic acid; endosulfan.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC499241; RGD1563998; Scube2-ps1; signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain, EGF-like 2; signal peptide, CUB domain, EGF-like 2, pseudogene 1; similar to Cegp1 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	173,264,862 - 173,341,323 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	173,264,865 - 173,334,372 (-)	Ensembl				GRCr8
mRatBN7.2	1	163,831,876 - 163,899,925 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	163,832,015 - 163,899,393 (-)	Ensembl				mRatBN7.2
Rnor_6.0	1	174,428,056 - 174,495,356 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	174,428,699 - 174,495,258 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	181,412,988 - 181,479,843 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	167,423,473 - 167,490,273 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	161,729,792 - 161,797,481 (-)	NCBI		Celera
Cytogenetic Map	1	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

calcitriol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

copper(II) sulfate (ISO)

cyclophosphamide (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dimethylarsinic acid (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

folic acid (ISO)

gentamycin (EXP)

indometacin (ISO)

isoprenaline (ISO)

mercury dibromide (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-ethyl-N-nitrosourea (ISO)

nickel atom (ISO)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paclitaxel (ISO)

panobinostat (ISO)

paraquat (EXP)

phenylmercury acetate (ISO)

potassium dichromate (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

testosterone (ISO)

Tetrachlorobisphenol A (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chondrocyte differentiation involved in endochondral bone morphogenesis (ISO)

positive regulation of chondrocyte proliferation (ISO)

positive regulation of ossification (ISO)

positive regulation of osteoblast differentiation (ISO)

positive regulation of smoothened signaling pathway (IEA,ISO)

signal transduction (IBA)

Cellular Component

cell surface (IBA,IEA)

extracellular region (IEA)

extracellular space (IBA,ISO)

Molecular Function

calcium ion binding (IEA)

hedgehog family protein binding (ISO)

lipid binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:25639508	PMID:31734396

Genomics

Comparative Map Data

Scube2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	173,264,862 - 173,341,323 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	173,264,865 - 173,334,372 (-)	Ensembl				GRCr8
mRatBN7.2	1	163,831,876 - 163,899,925 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	163,832,015 - 163,899,393 (-)	Ensembl				mRatBN7.2
Rnor_6.0	1	174,428,056 - 174,495,356 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	174,428,699 - 174,495,258 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	181,412,988 - 181,479,843 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	167,423,473 - 167,490,273 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	161,729,792 - 161,797,481 (-)	NCBI		Celera
Cytogenetic Map	1	q33	NCBI

SCUBE2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	9,019,476 - 9,091,599 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	9,019,476 - 9,138,114 (-)	Ensembl			hg38	GRCh38
GRCh37	11	9,041,023 - 9,113,146 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	8,998,511 - 9,069,731 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	8,998,510 - 9,069,731	NCBI
Celera	11	9,160,716 - 9,235,000 (-)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	8,711,371 - 8,785,710 (-)	NCBI		HuRef
CHM1_1	11	9,040,008 - 9,112,061 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	9,103,686 - 9,176,371 (-)	NCBI		T2T-CHM13v2.0

Scube2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	109,397,897 - 109,464,886 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	109,397,883 - 109,464,886 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	109,798,690 - 109,865,679 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	109,798,676 - 109,865,679 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	116,942,204 - 117,009,193 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	109,589,826 - 109,656,831 (-)	NCBI		MGSCv36	mm8
Celera	7	109,772,842 - 109,839,829 (-)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	57.53	NCBI

Scube2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	24,752,629 - 24,818,336 (-)	Ensembl
ChiLan1.0	NW_004955414	24,751,134 - 24,818,338 (-)	NCBI	ChiLan1.0	ChiLan1.0

SCUBE2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	11,454,241 - 11,526,231 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	11,412,582 - 11,484,448 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	9,146,533 - 9,219,816 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	8,887,127 - 8,959,669 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	8,888,668 - 8,959,677 (-)	Ensembl			panPan2	panpan1.1

SCUBE2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	32,370,361 - 32,435,608 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	32,370,913 - 32,574,588 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	31,939,474 - 32,003,782 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	33,244,992 - 33,309,462 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	33,244,992 - 33,309,419 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	32,514,102 - 32,578,016 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	32,680,598 - 32,744,570 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	32,974,398 - 33,038,307 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Scube2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	52,947,103 - 53,025,364 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936528	8,981,077 - 9,061,261 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936528	8,981,079 - 9,060,033 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCUBE2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	389,806 - 457,651 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	458,802 - 520,456 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCUBE2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	55,719,578 - 55,792,950 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	55,722,250 - 55,791,371 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	153,407,435 - 153,480,897 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Scube2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	1,151,793 - 1,241,774 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624766	1,158,607 - 1,241,797 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Scube2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	91,604,628 - 91,669,696 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Scube2
374 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	36
Count of miRNA genes:	34
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000052377
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	131179947	176179947	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	153679879	198679879	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	153679879	205813246	Rat
8694166	Bw147	Body weight QTL 147	6.83	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	1	153788989	198788989	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	160573753	210707719	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	160573753	210707719	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	165278545	210278545	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	161077990	206077990	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	168063662	213063662	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	159894717	207261263	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	163992710	208992710	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	155359438	194575574	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	131243790	176243790	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	129182274	174182274	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	162753891	207753891	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	153680016	182383862	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	153680016	183564652	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	172718770	228180370	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
1582204	Livw1	Liver weight QTL 1	3.6	0.0003	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	1	170078537	182384005	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	178317588	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	210707719	Rat
8693608	Alc24	Alcohol consumption QTL 24	2.3	0.74	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	1	159863716	177663210	Rat
1576310	Schws2	Schwannoma susceptibility QTL 2		0.029	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	1	153788989	198788989	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	165707719	210707719	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
7411599	Foco11	Food consumption QTL 11	18.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	1	153788989	198788989	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	210707719	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	12	67	160	87	86	55	82	55	6	333	182	11	139	77	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003753330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000052377 ⟹ ENSRNOP00000045001

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	173,264,865 - 173,334,234 (-)	Ensembl
mRatBN7.2 Ensembl	1	163,832,015 - 163,899,393 (-)	Ensembl
Rnor_6.0 Ensembl	1	174,428,699 - 174,495,258 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086349 ⟹ ENSRNOP00000069415

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	173,264,865 - 173,334,372 (-)	Ensembl
mRatBN7.2 Ensembl	1	163,832,015 - 163,899,393 (-)	Ensembl
Rnor_6.0 Ensembl	1	174,428,702 - 174,495,258 (-)	Ensembl

RefSeq Acc Id:

NM_001427604 ⟹ NP_001414533

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	173,264,865 - 173,334,234 (-)	NCBI

RefSeq Acc Id:

XM_006230005 ⟹ XP_006230067

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	173,264,862 - 173,341,320 (-)	NCBI
mRatBN7.2	1	163,831,876 - 163,899,919 (-)	NCBI
Rnor_6.0	1	174,428,056 - 174,495,356 (-)	NCBI
Rnor_5.0	1	181,412,988 - 181,479,843 (-)	NCBI

Sequence:

show sequence

CCGGGGGTGTCCGCGGGCGCAGAAGCCGGGAGCCCGCACACGCCTCCCCGCGCCGCTACCGCCG
CCGGCTCTCCGCCGCTCCGCGCGCTGCGGCTGCCATGGGGGTCGCGGGCTGCGGTCGGCCTTCG
GAGGCCCGGGCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCGCCGCTGCCGCTGCTGGCCT
CTGCCGTCCCACCCGACCAGGGTCGCACCAACGGGCCGCCCGAGGACATGGATGAATGTGACAA
TGCTCTCAATGGAGGCTGTGTCCACGACTGTTTAAACATCCCAGGCAACTATCGCTGCACCTGT
TTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTGTCTTGATGTGGATGAATGCTTGGAGA
ACAATGGCGGCTGCCAGCACACCTGCACCAACGTCATGGGGAGCTATGAGTGTCGCTGCAAAGA
AGGTTTCTTTCTAAGTGACAATCAGCACACTTGCATTCACCGCTCAGAAGAGGGCCTGAGCTGT
ATGAACAAGGATCATGGCTGTGCTCACATCTGCAAAGAGGCCCCGAGAGGCAGCATTGCCTGTG
AATGCAGGCCTGGTTTTGAACTGGCCAAAAACCAGAGAGACTGCATCTTGACCTGTAACCATGG
AAATGGTGGGTGTCAGCACTCCTGTGAAGATACTGCAGAAGGCCCCGAGTGTAGCTGCCATCCA
CACTACAGGTTGCATGCTGATGGGAGAAGCTGCCTAGAGCAAGAGGGTACCATGCTGGAGGGGA
CGGAGAGCAATGCCACGTCAGTGGCAGATGGAGATAAACGGGTGAAGCGGCGGCTGCTCATGGA
AACGTGTGCTGTCAACAATGGAGGCTGCGACCGCACCTGTAAGGACACGTCAACAGGCGTCCAC
TGCAGTTGTCCCTCTGGATTCACTCTCCAGTTGGATGGGAAGACATGTAAAGATATCGATGAGT
GCCAGACCCGGAATGGAGGTTGTAATCATTTCTGCAAAAACACTGTGGGCAGTTTTGACTGCAG
CTGCAGAAAAGGATTTAAATTACTAACAGACGAGAAGTCTTGCCAAGATGTGGATGAATGTTCT
TTGGAAAGGACCTGTGACCACAGCTGCATCAACCACCCTGGTACATTTACGTGTGCCTGCAATA
GAGGATACACTCTCTATAGCTTCACCCACTGTGGAGACACCAACGAGTGCAGCGTCAACAACGG
AGGCTGCCAGCAAGTTTGCGTCAACACAGTGGGTGGCTATGAGTGCCAGTGTCATCCAGGGTAC
AAGCTCCACTGGAATAAAAAAGACTGTGTGGAAGTAAAGGGCGTCCTGCCCACTAGCACGACAC
CCCGTGTGTCCCTGCACTGTGGTAAAAGTGGTGGAGGAGACAGGTGCTTCCTAAGATGCCATTC
TGGCATTCACCTCTCGTCAGGACTGCAAGAGGCTTACTCTGTCACCTGCGGCTCTCCCTCTCTC
AGAAGCAGACAGCAAAAATCAAATGACTCTGCTTTTGGGGATGTCGTCACCGTCAGGACAAGTG
TAACCTTTAAGCTAAACGAAGGCAAGTGTAGTTTGCAAAAGGCCAAGCTGTCTCCCGAGGGCCT
GCGACCAGCATTACCAGAGAGGCACAGCTCAGTAAAAGAGAGCTTCCACTACGCAAACCTTACA
TGCAGCCCTGGCAAGCAAGTCCTGGGAGCCCTTGGCCGACCGAACGCCCCTAAGGAAATGTTTA
TCACGGTTGAGTTTGAACGGGAAACTTACCAAAAGGAGGTGACAGCTTCCTGCAATCTGAGCTG
CGTGGTGAAGCGAACAGAGAAGAGGCTGCGGAAAGCTGTGCGCACACTCAAGAAGGCTGCCCAC
AGGGAACAGTTTCACCTGCAGCTCTCAGGCACGGACCTCGATGTGGCTAAAAAGTTTCCCCGAG
TGTCGGGACAGCAGGAGGAGACCTGTGGAGTGGGCCAGGGTCGTGAAGAAAGCCAGTGTGGCCT
TTGTCAGCCGGGTGAATATTCAGCAGATGGATTTGCCCCTTGCCAGCCCTGTGCCCTGGGCACC
TTTCAGCCTGATGTGGGCCGTACATCTTGCCTCCCGTGTGGAGGAGGTCTTCCTACTAAGCATC
TGGGAGCCACTTCCTTCCATGATTGTGAAACCAGAGTTCAATGTTCGCCTGGGCATTTCTACAA
CACCACCACACACCGATGTATCCGTTGCCCACTGGGAACATACCAGCCTGAATTTGGAAAAAAT
AATTGTGTTTCCTGCCCGGGAAATACTACCACCGACTTTGACGGCTCCACCAACATAACACAGT
GTAAAAACAGAAAGTGTGGAGGGGAGCTGGGGGATTTCACAGGGTACATTGAATCCCCAAACTA
CCCTGGGAACTACCCAGCCAACTCAGAGTGCACCTGGACCATTAACCCACCCCCCAAACGCCGG
ATCCTGATTGTGGTCCCTGAGATCTTCCTGCCCATAGAGGATGACTGCGGTGACTACCTGGTGA
TGCGGAAAACCTCTTCATCAAATTCTGTGACCACATATGAAACCTGCCAGACCTATGAACGCCC
CATCGCCTTCACCTCCAGATCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGGAACAGT
GCCCGAGGATTCCAGGTTCCCTATGTGACATACGATGAAGACTACCAGGAGCTCATTGAAGACA
TAGTCCGAGATGGCAGGCTCTATGCGTCTGAGAACCACCAGGAAATACTGAAGGATAAGAAACT
GATCAAGGCTCTGTTTGATGTCCTGGCACATCCCCAGAACTATTTCAAGTACACAGCCCAGGAG
TCCCGGGAGATGTTTCCAAGATCTTTCATCCGATTGCTACGTTCCAAAGTGTCAAGGTTTCTGA
GGCCTTACAAATGACTCTTCCCACATACCACCCTGAACAGGGTCCTACTGTGGGCTCAGTGGGC
TGCAGCCGTCTCCCCTCCACACGCCGGCCTGCCATCGGATCATTGCCACGCCCAGTATCAGTGA
CTGGTCAGAGTTCAGTTTTTATAGACAGCACAGATATCTTGGTAAACTGAACTTGGGTTTTCTC
TCCCAGTATTTCAGATGTGGACTGCATACATCTTGAGCAGCACTGTGTGGGCGCATGCCCTGGA
TGTCCTGAGGGCTGGCTGGACTGGCCTCCCCTTGGGTTCTCACTCCTTCAACTGTCTGTAGTGG
AAAGGAGGCCACTCTAGCTGCATCTCCATTTCCTCCTGGCCGGTCCTCTCCCAGGGAGCATCTG
TACTCATCAGAGTGACCAGGCCAAAGAGGCAAGCAGGAGGGGAGGACAAGCACTCCAGGAGACT
CCCGGGCCTTCTGAGTCAGGGGAAGACTCAGGTCCTCCCGGGCTTCTGCAGCCTCTGCAATGCC
AGTTTAATCCTAACCGAGTGGGTCCTAAGCAGTGATTTTTTTTTTAAAGACCAGAAAGAATTAG
AAATAAAAAGGCCCCCCTGGAGGCATGAATAGCACGCACATGCACATGCACACGTGTACACACA
CACACACACACACACAC

hide sequence

RefSeq Acc Id:

XM_006230006 ⟹ XP_006230068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	173,264,862 - 173,341,320 (-)	NCBI
mRatBN7.2	1	163,831,876 - 163,899,919 (-)	NCBI
Rnor_6.0	1	174,428,056 - 174,495,356 (-)	NCBI
Rnor_5.0	1	181,412,988 - 181,479,843 (-)	NCBI

Sequence:

show sequence

CCGGGGGTGTCCGCGGGCGCAGAAGCCGGGAGCCCGCACACGCCTCCCCGCGCCGCTACCGCCG
CCGGCTCTCCGCCGCTCCGCGCGCTGCGGCTGCCATGGGGGTCGCGGGCTGCGGTCGGCCTTCG
GAGGCCCGGGCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCGCCGCTGCCGCTGCTGGCCT
CTGCCGTCCCACCCGACCAGGGTCGCACCAACGGGCCGCCCGAGGATGTGGATGAGTGTGCCCA
AGGGCTGGATGACTGCCATGCTGATGCACTGTGTCAAAACACACCCACTTCCTACAAGTGCTCT
TGTAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATGGATGAATGTGACAATGCTC
TCAATGGAGGCTGTGTCCACGACTGTTTAAACATCCCAGGCAACTATCGCTGCACCTGTTTTGA
TGGCTTCATGTTGGCTCATGACGGTCATAATTGTCTTGATGTGGATGAATGCTTGGAGAACAAT
GGCGGCTGCCAGCACACCTGCACCAACGTCATGGGGAGCTATGAGTGTCGCTGCAAAGAAGGTT
TCTTTCTAAGTGACAATCAGCACACTTGCATTCACCGCTCAGAAGAGGGCCTGAGCTGTATGAA
CAAGGATCATGGCTGTGCTCACATCTGCAAAGAGGCCCCGAGAGGCAGCATTGCCTGTGAATGC
AGGCCTGGTTTTGAACTGGCCAAAAACCAGAGAGACTGCATCTTGACCTGTAACCATGGAAATG
GTGGGTGTCAGCACTCCTGTGAAGATACTGCAGAAGGCCCCGAGTGTAGCTGCCATCCACACTA
CAGGTTGCATGCTGATGGGAGAAGCTGCCTAGAGCAAGAGGGTACCATGCTGGAGGGGACGGAG
AGCAATGCCACGTCAGTGGCAGATGGAGATAAACGGGTGAAGCGGCGGCTGCTCATGGAAACGT
GTGCTGTCAACAATGGAGGCTGCGACCGCACCTGTAAGGACACGTCAACAGGCGTCCACTGCAG
TTGTCCCTCTGGATTCACTCTCCAGTTGGATGGGAAGACATGTAAAGATATCGATGAGTGCCAG
ACCCGGAATGGAGGTTGTAATCATTTCTGCAAAAACACTGTGGGCAGTTTTGACTGCAGCTGCA
GAAAAGGATTTAAATTACTAACAGACGAGAAGTCTTGCCAAGATGTGGATGAATGTTCTTTGGA
AAGGACCTGTGACCACAGCTGCATCAACCACCCTGGTACATTTACGTGTGCCTGCAATAGAGGA
TACACTCTCTATAGCTTCACCCACTGTGGAGACACCAACGAGTGCAGCGTCAACAACGGAGGCT
GCCAGCAAGTTTGCGTCAACACAGTGGGTGGCTATGAGTGCCAGTGTCATCCAGGGTACAAGCT
CCACTGGAATAAAAAAGACTGTGTGGCTTCCTGCAATCTGAGCTGCGTGGTGAAGCGAACAGAG
AAGAGGCTGCGGAAAGCTGTGCGCACACTCAAGAAGGCTGCCCACAGGGAACAGTTTCACCTGC
AGCTCTCAGGCACGGACCTCGATGTGGCTAAAAAGTTTCCCCGAGTGTCGGGACAGCAGGAGGA
GACCTGTGGAGTGGGCCAGGGTCGTGAAGAAAGCCAGTGTGGCCTTTGTCAGCCGGGTGAATAT
TCAGCAGATGGATTTGCCCCTTGCCAGCCCTGTGCCCTGGGCACCTTTCAGCCTGATGTGGGCC
GTACATCTTGCCTCCCGTGTGGAGGAGGTCTTCCTACTAAGCATCTGGGAGCCACTTCCTTCCA
TGATTGTGAAACCAGAGTTCAATGTTCGCCTGGGCATTTCTACAACACCACCACACACCGATGT
ATCCGTTGCCCACTGGGAACATACCAGCCTGAATTTGGAAAAAATAATTGTGTTTCCTGCCCGG
GAAATACTACCACCGACTTTGACGGCTCCACCAACATAACACAGTGTAAAAACAGAAAGTGTGG
AGGGGAGCTGGGGGATTTCACAGGGTACATTGAATCCCCAAACTACCCTGGGAACTACCCAGCC
AACTCAGAGTGCACCTGGACCATTAACCCACCCCCCAAACGCCGGATCCTGATTGTGGTCCCTG
AGATCTTCCTGCCCATAGAGGATGACTGCGGTGACTACCTGGTGATGCGGAAAACCTCTTCATC
AAATTCTGTGACCACATATGAAACCTGCCAGACCTATGAACGCCCCATCGCCTTCACCTCCAGA
TCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGGAACAGTGCCCGAGGATTCCAGGTTC
CCTATGTGACATACGATGAAGACTACCAGGAGCTCATTGAAGACATAGTCCGAGATGGCAGGCT
CTATGCGTCTGAGAACCACCAGGAAATACTGAAGGATAAGAAACTGATCAAGGCTCTGTTTGAT
GTCCTGGCACATCCCCAGAACTATTTCAAGTACACAGCCCAGGAGTCCCGGGAGATGTTTCCAA
GATCTTTCATCCGATTGCTACGTTCCAAAGTGTCAAGGTTTCTGAGGCCTTACAAATGACTCTT
CCCACATACCACCCTGAACAGGGTCCTACTGTGGGCTCAGTGGGCTGCAGCCGTCTCCCCTCCA
CACGCCGGCCTGCCATCGGATCATTGCCACGCCCAGTATCAGTGACTGGTCAGAGTTCAGTTTT
TATAGACAGCACAGATATCTTGGTAAACTGAACTTGGGTTTTCTCTCCCAGTATTTCAGATGTG
GACTGCATACATCTTGAGCAGCACTGTGTGGGCGCATGCCCTGGATGTCCTGAGGGCTGGCTGG
ACTGGCCTCCCCTTGGGTTCTCACTCCTTCAACTGTCTGTAGTGGAAAGGAGGCCACTCTAGCT
GCATCTCCATTTCCTCCTGGCCGGTCCTCTCCCAGGGAGCATCTGTACTCATCAGAGTGACCAG
GCCAAAGAGGCAAGCAGGAGGGGAGGACAAGCACTCCAGGAGACTCCCGGGCCTTCTGAGTCAG
GGGAAGACTCAGGTCCTCCCGGGCTTCTGCAGCCTCTGCAATGCCAGTTTAATCCTAACCGAGT
GGGTCCTAAGCAGTGATTTTTTTTTTAAAGACCAGAAAGAATTAGAAATAAAAAGGCCCCCCTG
GAGGCATGAATAGCACGCACATGCACATGCACACGTGTACACACACACACACACACACACAC

hide sequence

RefSeq Acc Id:

XM_039094567 ⟹ XP_038950495

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	173,272,738 - 173,341,323 (-)	NCBI
mRatBN7.2	1	163,837,953 - 163,899,925 (-)	NCBI

RefSeq Acc Id:

XM_063271300 ⟹ XP_063127370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	173,264,862 - 173,341,320 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001414533	(Get FASTA)	NCBI Sequence Viewer
	XP_006230067	(Get FASTA)	NCBI Sequence Viewer
	XP_006230068	(Get FASTA)	NCBI Sequence Viewer
	XP_038950495	(Get FASTA)	NCBI Sequence Viewer
	XP_063127370	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM17886	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045001
	ENSRNOP00000045001.4
	ENSRNOP00000069415
	ENSRNOP00000069415.3

RefSeq Acc Id:

XP_006230067 ⟸ XM_006230005

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGVAGCGRPSEARALLLLLLLLLPPPLPLLASAVPPDQGRTNGPPEDMDECDNALNGGCVHDCL
NIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCTNVMGSYECRCKEGFFLSDNQHTC
IHRSEEGLSCMNKDHGCAHICKEAPRGSIACECRPGFELAKNQRDCILTCNHGNGGCQHSCEDT
AEGPECSCHPHYRLHADGRSCLEQEGTMLEGTESNATSVADGDKRVKRRLLMETCAVNNGGCDR
TCKDTSTGVHCSCPSGFTLQLDGKTCKDIDECQTRNGGCNHFCKNTVGSFDCSCRKGFKLLTDE
KSCQDVDECSLERTCDHSCINHPGTFTCACNRGYTLYSFTHCGDTNECSVNNGGCQQVCVNTVG
GYECQCHPGYKLHWNKKDCVEVKGVLPTSTTPRVSLHCGKSGGGDRCFLRCHSGIHLSSGLQEA
YSVTCGSPSLRSRQQKSNDSAFGDVVTVRTSVTFKLNEGKCSLQKAKLSPEGLRPALPERHSSV
KESFHYANLTCSPGKQVLGALGRPNAPKEMFITVEFERETYQKEVTASCNLSCVVKRTEKRLRK
AVRTLKKAAHREQFHLQLSGTDLDVAKKFPRVSGQQEETCGVGQGREESQCGLCQPGEYSADGF
APCQPCALGTFQPDVGRTSCLPCGGGLPTKHLGATSFHDCETRVQCSPGHFYNTTTHRCIRCPL
GTYQPEFGKNNCVSCPGNTTTDFDGSTNITQCKNRKCGGELGDFTGYIESPNYPGNYPANSECT
WTINPPPKRRILIVVPEIFLPIEDDCGDYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLW
IQFKSNEGNSARGFQVPYVTYDEDYQELIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHP
QNYFKYTAQESREMFPRSFIRLLRSKVSRFLRPYK

hide sequence

RefSeq Acc Id:	XP_006230068 ⟸ XM_006230006
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2JVB2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGVAGCGRPSEARALLLLLLLLLPPPLPLLASAVPPDQGRTNGPPEDVDECAQGLDDCHADALC QNTPTSYKCSCKPGYQGEGRQCEDMDECDNALNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC LDVDECLENNGGCQHTCTNVMGSYECRCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCAHICKE APRGSIACECRPGFELAKNQRDCILTCNHGNGGCQHSCEDTAEGPECSCHPHYRLHADGRSCLE QEGTMLEGTESNATSVADGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPSGFTLQLDG KTCKDIDECQTRNGGCNHFCKNTVGSFDCSCRKGFKLLTDEKSCQDVDECSLERTCDHSCINHP GTFTCACNRGYTLYSFTHCGDTNECSVNNGGCQQVCVNTVGGYECQCHPGYKLHWNKKDCVASC NLSCVVKRTEKRLRKAVRTLKKAAHREQFHLQLSGTDLDVAKKFPRVSGQQEETCGVGQGREES QCGLCQPGEYSADGFAPCQPCALGTFQPDVGRTSCLPCGGGLPTKHLGATSFHDCETRVQCSPG HFYNTTTHRCIRCPLGTYQPEFGKNNCVSCPGNTTTDFDGSTNITQCKNRKCGGELGDFTGYIE SPNYPGNYPANSECTWTINPPPKRRILIVVPEIFLPIEDDCGDYLVMRKTSSSNSVTTYETCQT YERPIAFTSRSKKLWIQFKSNEGNSARGFQVPYVTYDEDYQELIEDIVRDGRLYASENHQEILK DKKLIKALFDVLAHPQNYFKYTAQESREMFPRSFIRLLRSKVSRFLRPYK hide sequence

Ensembl Acc Id:

ENSRNOP00000069415 ⟸ ENSRNOT00000086349

Ensembl Acc Id:

ENSRNOP00000045001 ⟸ ENSRNOT00000052377

RefSeq Acc Id:	XP_038950495 ⟸ XM_039094567
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063127370 ⟸ XM_063271300
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2JVB2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001414533 ⟸ NM_001427604
- Peptide Label:	precursor
- UniProtKB:	D4AC02 (UniProtKB/TrEMBL)

Protein Domains

CUB EGF-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JVB2-F1-model_v2	AlphaFold	A0A0G2JVB2	1-1000	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690316

Promoter ID:

EPDNEW_R831

Type:

single initiation site

Name:

Scube2_1

Description:

signal peptide, CUB domain and EGF like domain containing 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	174,495,219 - 174,495,279	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563998	AgrOrtholog
BioCyc Gene	G2FUF-57853	BioCyc
Ensembl Genes	ENSRNOG00000013123	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000052377	ENTREZGENE
	ENSRNOT00000052377.6	UniProtKB/TrEMBL
	ENSRNOT00000086349	ENTREZGENE
	ENSRNOT00000086349.3	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.290	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
	Tumor Necrosis Factor Receptor, subunit A, domain 2	UniProtKB/TrEMBL
InterPro	cEGF	UniProtKB/TrEMBL
	CUB	UniProtKB/TrEMBL
	EG-like_dom	UniProtKB/TrEMBL
	EGF-like_Ca-bd	UniProtKB/TrEMBL
	EGF-type_Asp/Asn_hydroxyl_site	UniProtKB/TrEMBL
	EGF_Ca-bd_CS	UniProtKB/TrEMBL
	EGF_dom	UniProtKB/TrEMBL
	Growth_fac_rcpt	UniProtKB/TrEMBL
	NOTCH1_EGF-like	UniProtKB/TrEMBL
	SCUB_EGF-like_domain	UniProtKB/TrEMBL
	sperma_CUB_dom	UniProtKB/TrEMBL
	Tyr-kin_ephrin_A/B_rcpt-like	UniProtKB/TrEMBL
NCBI Gene	499241	ENTREZGENE
PANTHER	SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING	UniProtKB/TrEMBL
	SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
Pfam	cEGF	UniProtKB/TrEMBL
	CUB	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	FXa_inhibition	UniProtKB/TrEMBL
	GCC2_GCC3	UniProtKB/TrEMBL
PhenoGen	Scube2	PhenoGen
PROSITE	ASX_HYDROXYL	UniProtKB/TrEMBL
	CUB	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013123	RatGTEx
SMART	CUB	UniProtKB/TrEMBL
	EGF	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	Ephrin_rec_like	UniProtKB/TrEMBL
Superfamily-SCOP	CUB	UniProtKB/TrEMBL
	EGF/Laminin	UniProtKB/TrEMBL
	Grow_fac_recept	UniProtKB/TrEMBL
UniProt	A0A0G2JVB2	ENTREZGENE, UniProtKB/TrEMBL
	D4AC02	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-27	Scube2	signal peptide, CUB domain and EGF like domain containing 2	Scube2	signal peptide, CUB domain, EGF-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-03-07	Scube2	signal peptide, CUB domain, EGF-like 2	Scube2-ps1	signal peptide, CUB domain, EGF-like 2, pseudogene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-06-09	Scube2-ps1	signal peptide, CUB domain, EGF-like 2, pseudogene 1	Scube2	signal peptide, CUB domain, EGF-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Scube2	signal peptide, CUB domain, EGF-like 2	RGD1563998_predicted	similar to Cegp1 protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1563998_predicted	similar to Cegp1 protein (predicted)	LOC499241	similar to Cegp1 protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC499241	similar to Cegp1 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message