Tc2n (tandem C2 domains, nuclear) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Tc2n (tandem C2 domains, nuclear) Rattus norvegicus
Analyze
Symbol: Tc2n
Name: tandem C2 domains, nuclear
RGD ID: 1563876
Description: Predicted to be active in nucleus. Orthologous to human TC2N (tandem C2 domains, nuclear); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: membrane targeting (tandem) C2 domain containing 1; Mtac2d1; Tac2-N
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,526,006 - 126,622,163 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6126,526,009 - 126,614,215 (-)EnsemblGRCr8
mRatBN7.26120,761,112 - 120,856,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,761,119 - 120,849,326 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6120,902,128 - 120,998,937 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06121,198,818 - 121,295,627 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,533,692 - 120,630,507 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,437,767 - 125,601,408 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,437,775 - 125,590,049 (-)Ensemblrn6Rnor6.0
Rnor_5.06134,651,335 - 134,813,686 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46125,871,936 - 125,975,388 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6118,263,473 - 118,355,476 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
clofibric acid  (EXP)
cobalt atom  (ISO)
coumestrol  (ISO)
D-glucose  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
fructose  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glucose  (ISO)
glycitein  (ISO)
glycitin  (ISO)
glyphosate  (EXP)
indole-3-methanol  (EXP)
lead diacetate  (EXP)
lead(0)  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
ozone  (ISO)
panobinostat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11526914   PMID:21810271  


Genomics

Comparative Map Data
Tc2n
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,526,006 - 126,622,163 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6126,526,009 - 126,614,215 (-)EnsemblGRCr8
mRatBN7.26120,761,112 - 120,856,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,761,119 - 120,849,326 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6120,902,128 - 120,998,937 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06121,198,818 - 121,295,627 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,533,692 - 120,630,507 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,437,767 - 125,601,408 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,437,775 - 125,590,049 (-)Ensemblrn6Rnor6.0
Rnor_5.06134,651,335 - 134,813,686 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46125,871,936 - 125,975,388 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6118,263,473 - 118,355,476 (-)NCBICelera
Cytogenetic Map6q32NCBI
TC2N
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381491,779,746 - 91,867,536 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1491,779,746 - 91,867,536 (-)Ensemblhg38GRCh38
GRCh371492,246,090 - 92,333,880 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361491,316,279 - 91,372,436 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341491,316,278 - 91,372,436NCBI
Celera1472,298,880 - 72,386,499 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1472,426,963 - 72,514,634 (-)NCBIHuRef
CHM1_11492,184,339 - 92,271,959 (-)NCBICHM1_1
T2T-CHM13v2.01486,009,200 - 86,097,026 (-)NCBIT2T-CHM13v2.0
Tc2n
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912101,611,705 - 101,685,178 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12101,611,702 - 101,684,782 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812101,645,446 - 101,718,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12101,645,443 - 101,718,523 (-)Ensemblmm10GRCm38
MGSCv3712102,886,812 - 102,956,712 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612102,047,613 - 102,112,955 (-)NCBIMGSCv36mm8
Celera12102,856,104 - 102,924,262 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.26NCBI
Tc2n
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543814,000,322 - 14,047,415 (-)Ensembl
ChiLan1.0NW_00495543814,012,199 - 14,047,174 (-)NCBIChiLan1.0ChiLan1.0
TC2N
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21592,927,742 - 92,995,133 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11492,144,251 - 92,211,642 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,404,915 - 72,471,347 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11491,750,265 - 91,815,703 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1491,750,265 - 91,815,703 (-)EnsemblpanPan2panpan1.1
TC2N
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,088,618 - 1,160,322 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,093,201 - 1,133,626 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha81,108,421 - 1,179,516 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.081,138,284 - 1,209,449 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl81,140,398 - 1,183,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.181,076,424 - 1,147,466 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,032,477 - 1,103,930 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.081,153,646 - 1,224,733 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tc2n
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,360,791 - 13,396,425 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493673372,304 - 99,767 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493673370,608 - 106,247 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TC2N
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7113,337,035 - 113,389,588 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17113,337,815 - 113,389,663 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27119,945,860 - 119,997,695 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TC2N
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12469,538,975 - 69,624,868 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2469,537,693 - 69,593,341 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605356,787,917 - 56,843,315 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tc2n
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473410,889,439 - 10,912,189 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473410,877,974 - 10,912,859 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tc2n
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17120,108,626 - 120,161,081 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tc2n
789 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:102
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000006371
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 148 91 90 59 26 59 6 289 125 11 127 81 92 31 11 11

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU240047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000006371   ⟹   ENSRNOP00000006371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6126,526,009 - 126,614,215 (-)Ensembl
mRatBN7.2 Ensembl6120,761,119 - 120,849,326 (-)Ensembl
Rnor_6.0 Ensembl6125,437,775 - 125,590,049 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098176   ⟹   ENSRNOP00000077072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6126,526,009 - 126,614,215 (-)Ensembl
mRatBN7.2 Ensembl6120,761,119 - 120,849,326 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000140300   ⟹   ENSRNOP00000105439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6126,526,009 - 126,614,215 (-)Ensembl
RefSeq Acc Id: NM_001025152   ⟹   NP_001020323
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,637 (-)NCBI
mRatBN7.26120,761,116 - 120,856,750 (-)NCBI
Rnor_6.06125,437,767 - 125,601,316 (-)NCBI
Rnor_5.06134,651,335 - 134,813,686 (-)NCBI
RGSC_v3.46125,871,936 - 125,975,388 (-)RGD
Celera6118,263,473 - 118,355,476 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764836   ⟹   XP_008763058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,722 (-)NCBI
mRatBN7.26120,761,116 - 120,856,835 (-)NCBI
Rnor_6.06125,437,767 - 125,601,408 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112744   ⟹   XP_038968672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,622,163 (-)NCBI
mRatBN7.26120,761,112 - 120,856,835 (-)NCBI
RefSeq Acc Id: XM_039112745   ⟹   XP_038968673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,722 (-)NCBI
mRatBN7.26120,761,112 - 120,856,835 (-)NCBI
RefSeq Acc Id: XM_039112746   ⟹   XP_038968674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,613,983 (-)NCBI
mRatBN7.26120,761,112 - 120,849,045 (-)NCBI
RefSeq Acc Id: XM_039112747   ⟹   XP_038968675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,722 (-)NCBI
mRatBN7.26120,761,112 - 120,856,835 (-)NCBI
RefSeq Acc Id: XM_039112750   ⟹   XP_038968678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,729 (-)NCBI
mRatBN7.26120,761,112 - 120,856,835 (-)NCBI
RefSeq Acc Id: XM_039112753   ⟹   XP_038968681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,607,893 (-)NCBI
mRatBN7.26120,761,112 - 120,842,931 (-)NCBI
RefSeq Acc Id: XM_039112754   ⟹   XP_038968682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,587,427 (-)NCBI
mRatBN7.26120,761,112 - 120,822,508 (-)NCBI
RefSeq Acc Id: XM_063262322   ⟹   XP_063118392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,622,004 (-)NCBI
RefSeq Acc Id: XM_063262323   ⟹   XP_063118393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262324   ⟹   XP_063118394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262325   ⟹   XP_063118395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262326   ⟹   XP_063118396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262327   ⟹   XP_063118397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262328   ⟹   XP_063118398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262329   ⟹   XP_063118399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262330   ⟹   XP_063118400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,542,011 - 126,621,722 (-)NCBI
RefSeq Acc Id: XM_063262331   ⟹   XP_063118401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,622,004 (-)NCBI
RefSeq Acc Id: XM_063262332   ⟹   XP_063118402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,526,006 - 126,621,722 (-)NCBI
RefSeq Acc Id: NP_001020323   ⟸   NM_001025152
- UniProtKB: Q5M7U8 (UniProtKB/TrEMBL),   E9PTC2 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763058   ⟸   XM_008764836
- Peptide Label: isoform X2
- UniProtKB: Q5M7U8 (UniProtKB/TrEMBL),   E9PTC2 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006371   ⟸   ENSRNOT00000006371
RefSeq Acc Id: XP_038968678   ⟸   XM_039112750
- Peptide Label: isoform X2
- UniProtKB: E9PTC2 (UniProtKB/TrEMBL),   Q5M7U8 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968672   ⟸   XM_039112744
- Peptide Label: isoform X2
- UniProtKB: E9PTC2 (UniProtKB/TrEMBL),   Q5M7U8 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968675   ⟸   XM_039112747
- Peptide Label: isoform X2
- UniProtKB: E9PTC2 (UniProtKB/TrEMBL),   Q5M7U8 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968673   ⟸   XM_039112745
- Peptide Label: isoform X2
- UniProtKB: E9PTC2 (UniProtKB/TrEMBL),   Q5M7U8 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968674   ⟸   XM_039112746
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038968681   ⟸   XM_039112753
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038968682   ⟸   XM_039112754
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000077072   ⟸   ENSRNOT00000098176
RefSeq Acc Id: XP_063118401   ⟸   XM_063262331
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118402   ⟸   XM_063262332
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118399   ⟸   XM_063262329
- Peptide Label: isoform X2
- UniProtKB: E9PTC2 (UniProtKB/TrEMBL),   Q5M7U8 (UniProtKB/TrEMBL),   A0A8I5Y9B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118392   ⟸   XM_063262322
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118393   ⟸   XM_063262323
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118395   ⟸   XM_063262325
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118394   ⟸   XM_063262324
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118397   ⟸   XM_063262327
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118398   ⟸   XM_063262328
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118400   ⟸   XM_063262330
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118396   ⟸   XM_063262326
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000105439   ⟸   ENSRNOT00000140300
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M7U8-F1-model_v2 AlphaFold Q5M7U8 1-489 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563876 AgrOrtholog
BioCyc Gene G2FUF-36468 BioCyc
Ensembl Genes ENSRNOG00000004754 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006371 ENTREZGENE
  ENSRNOT00000006371.9 UniProtKB/TrEMBL
  ENSRNOT00000098176.2 UniProtKB/TrEMBL
  ENSRNOT00000140300.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7124658 IMAGE-MGC_LOAD
InterPro C2_Ca-dep UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2A_Tac2-N UniProtKB/TrEMBL
  C2B_Tac2-N UniProtKB/TrEMBL
  Tac2-N UniProtKB/TrEMBL
KEGG Report rno:500707 UniProtKB/TrEMBL
MGC_CLONE MGC:95063 IMAGE-MGC_LOAD
NCBI Gene 500707 ENTREZGENE
PANTHER PTHR46887 UniProtKB/TrEMBL
  TANDEM C2 DOMAINS NUCLEAR PROTEIN UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PhenoGen Tc2n PhenoGen
PROSITE PS50004 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004754 RatGTEx
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8I5Y9B0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LQR3_RAT UniProtKB/TrEMBL
  E9PTC2 ENTREZGENE
  Q5M7U8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PTC2 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Tc2n  tandem C2 domains, nuclear  Mtac2d1  membrane targeting (tandem) C2 domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Mtac2d1  membrane targeting (tandem) C2 domain containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL