Lmnb2 (lamin B2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Lmnb2 (lamin B2) Rattus norvegicus
Analyze
Symbol: Lmnb2
Name: lamin B2
RGD ID: 1563803
Description: Predicted to enable identical protein binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including heterochromatin formation; nucleus organization; and protein localization to nuclear envelope. Predicted to be located in lamin filament and nuclear membrane. Predicted to be active in nuclear lamina. Human ortholog(s) of this gene implicated in autosomal dominant primary microcephaly 27; partial lipodystrophy; and progressive myoclonus epilepsy 9. Orthologous to human LMNB2 (lamin B2); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lamin-B2; LOC299625; RGD1563803; similar to Lmnb2 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,443,308 - 9,459,468 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl79,440,128 - 9,459,342 (+)EnsemblGRCr8
mRatBN7.278,792,628 - 8,808,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,789,314 - 8,808,665 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx711,676,600 - 11,692,579 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,552,108 - 13,568,087 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,418,629 - 11,434,610 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd712,198,771 - 12,214,752 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive712,362,053 - 12,378,034 (+)NCBILyon_Normotensive
Lyon_Hypertensive712,437,067 - 12,453,048 (+)NCBILyon_Hypertensive
F344_StmMcwi710,803,079 - 10,819,060 (+)NCBIF344_StmMcwi
Rnor_6.0711,657,870 - 11,676,936 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,660,934 - 11,675,472 (+)Ensemblrn6Rnor6.0
Rnor_5.0711,828,299 - 11,844,456 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4710,303,626 - 10,326,068 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera76,976,982 - 6,993,012 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-nitrophenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
AM-251  (ISO)
aminoglutethimide  (ISO)
amphetamine  (EXP)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-carotene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
fenthion  (ISO)
flavone  (ISO)
FR900359  (ISO)
furfural  (ISO)
genistein  (EXP,ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
poly(vinylpyrrolidone)  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8032679   PMID:16364897   PMID:20457914   PMID:21842415   PMID:22349700   PMID:25002582  


Genomics

Comparative Map Data
Lmnb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,443,308 - 9,459,468 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl79,440,128 - 9,459,342 (+)EnsemblGRCr8
mRatBN7.278,792,628 - 8,808,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,789,314 - 8,808,665 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx711,676,600 - 11,692,579 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,552,108 - 13,568,087 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,418,629 - 11,434,610 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd712,198,771 - 12,214,752 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive712,362,053 - 12,378,034 (+)NCBILyon_Normotensive
Lyon_Hypertensive712,437,067 - 12,453,048 (+)NCBILyon_Hypertensive
F344_StmMcwi710,803,079 - 10,819,060 (+)NCBIF344_StmMcwi
Rnor_6.0711,657,870 - 11,676,936 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,660,934 - 11,675,472 (+)Ensemblrn6Rnor6.0
Rnor_5.0711,828,299 - 11,844,456 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4710,303,626 - 10,326,068 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera76,976,982 - 6,993,012 (+)NCBICelera
Cytogenetic Map7q11NCBI
LMNB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,428,166 - 2,456,959 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,427,638 - 2,456,992 (-)Ensemblhg38GRCh38
GRCh37192,428,164 - 2,456,957 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,379,164 - 2,407,958 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34192,379,164 - 2,407,958NCBI
Celera192,365,655 - 2,394,449 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef192,200,214 - 2,228,845 (-)NCBIHuRef
CHM1_1192,427,662 - 2,456,465 (-)NCBICHM1_1
T2T-CHM13v2.0192,403,957 - 2,432,750 (-)NCBIT2T-CHM13v2.0
Lmnb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,737,197 - 80,754,079 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,737,037 - 80,754,079 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381080,901,363 - 80,918,245 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,901,203 - 80,918,245 (-)Ensemblmm10GRCm38
MGSCv371080,364,108 - 80,380,990 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361080,304,492 - 80,321,334 (-)NCBIMGSCv36mm8
Celera1081,920,184 - 81,937,066 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Lmnb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,828,638 - 4,851,928 (-)Ensembl
ChiLan1.0NW_0049554954,826,653 - 4,851,984 (-)NCBIChiLan1.0ChiLan1.0
LMNB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2206,812,942 - 6,842,561 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,042,206 - 6,071,356 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0191,440,462 - 1,469,601 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1192,406,296 - 2,430,568 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,406,296 - 2,430,568 (-)EnsemblpanPan2panpan1.1
LMNB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,652,183 - 56,663,476 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,652,750 - 56,670,278 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2056,441,797 - 56,459,358 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02057,379,149 - 57,396,719 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2057,376,730 - 57,399,644 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12056,431,395 - 56,448,956 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,916,504 - 56,934,153 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,116,796 - 57,134,399 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lmnb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,369,489 - 216,386,878 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,448,277 - 1,465,376 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,448,195 - 1,465,332 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMNB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,125,927 - 76,146,558 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1276,125,932 - 76,146,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2276,677,404 - 76,698,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LMNB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,207,096 - 2,234,258 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl62,209,989 - 2,234,215 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660816,428,694 - 6,452,779 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lmnb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,633,191 - 5,648,240 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248285,630,328 - 5,648,231 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lmnb2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11153,965,498 - 153,983,162 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lmnb2
43 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:751
Count of miRNA genes:256
Interacting mature miRNAs:324
Transcripts:ENSRNOT00000022336, ENSRNOT00000075183
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
RH140520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,808,435 - 8,808,575 (+)MAPPERmRatBN7.2
Rnor_6.0711,676,707 - 11,676,846NCBIRnor6.0
Rnor_5.0711,844,227 - 11,844,366UniSTSRnor5.0
RGSC_v3.4710,319,326 - 10,319,465UniSTSRGSC3.4
Celera76,992,783 - 6,992,922UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022336   ⟹   ENSRNOP00000022336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,443,301 - 9,459,341 (+)Ensembl
mRatBN7.2 Ensembl78,792,628 - 8,808,665 (+)Ensembl
Rnor_6.0 Ensembl711,660,934 - 11,675,472 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094689   ⟹   ENSRNOP00000079276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,443,301 - 9,459,341 (+)Ensembl
mRatBN7.2 Ensembl78,792,628 - 8,808,665 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109213   ⟹   ENSRNOP00000086789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,440,128 - 9,459,342 (+)Ensembl
mRatBN7.2 Ensembl78,789,314 - 8,808,665 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114820   ⟹   ENSRNOP00000080459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,452,621 - 9,459,341 (+)Ensembl
mRatBN7.2 Ensembl78,802,878 - 8,808,665 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135093   ⟹   ENSRNOP00000105917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,445,988 - 9,459,342 (+)Ensembl
RefSeq Acc Id: NM_001305235   ⟹   NP_001292164
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,443,308 - 9,459,342 (+)NCBI
mRatBN7.278,792,628 - 8,808,665 (+)NCBI
Dahl_SR_JrHsd712,198,771 - 12,214,752 (+)NCBI
Lyon_Normotensive712,362,053 - 12,378,034 (+)NCBI
Lyon_Hypertensive712,437,067 - 12,453,048 (+)NCBI
F344_StmMcwi710,803,079 - 10,819,060 (+)NCBI
Rnor_6.0711,660,902 - 11,676,936 (+)NCBI
Celera76,976,982 - 6,993,012 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241035   ⟹   XP_006241097
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,453,299 - 9,459,468 (+)NCBI
mRatBN7.278,802,413 - 8,808,665 (+)NCBI
Rnor_6.0711,670,624 - 11,675,342 (+)NCBI
Rnor_5.0711,828,299 - 11,844,456 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263176   ⟹   XP_063119246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,448,625 - 9,459,468 (+)NCBI
RefSeq Acc Id: XP_006241097   ⟸   XM_006241035
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZPN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001292164   ⟸   NM_001305235
- UniProtKB: D3ZLC1 (UniProtKB/TrEMBL),   A0A8I5ZMS1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022336   ⟸   ENSRNOT00000022336
Ensembl Acc Id: ENSRNOP00000080459   ⟸   ENSRNOT00000114820
Ensembl Acc Id: ENSRNOP00000079276   ⟸   ENSRNOT00000094689
Ensembl Acc Id: ENSRNOP00000086789   ⟸   ENSRNOT00000109213
RefSeq Acc Id: XP_063119246   ⟸   XM_063263176
- Peptide Label: isoform X2
- UniProtKB: A6K8E0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105917   ⟸   ENSRNOT00000135093
Protein Domains
IF rod   LTD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLC1-F1-model_v2 AlphaFold D3ZLC1 1-616 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695008
Promoter ID:EPDNEW_R5521
Type:single initiation site
Name:Lmnb2_1
Description:lamin B2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,660,929 - 11,660,989EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563803 AgrOrtholog
BioCyc Gene G2FUF-34979 BioCyc
Ensembl Genes ENSRNOG00000025742 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022336 ENTREZGENE
  ENSRNOT00000022336.10 UniProtKB/TrEMBL
  ENSRNOT00000094689.2 UniProtKB/TrEMBL
  ENSRNOT00000109213.2 UniProtKB/TrEMBL
  ENSRNOT00000114820 ENTREZGENE
  ENSRNOT00000114820.2 UniProtKB/TrEMBL
  ENSRNOT00000135093.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  2.60.40.1260 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro IF_rod_dom UniProtKB/TrEMBL
  Lamin_tail_dom UniProtKB/TrEMBL
  Lamin_tail_dom_sf UniProtKB/TrEMBL
KEGG Report rno:299625 UniProtKB/TrEMBL
NCBI Gene 299625 ENTREZGENE
PANTHER LAMIN DM0-RELATED UniProtKB/TrEMBL
  LAMIN-B2 UniProtKB/TrEMBL
Pfam Filament UniProtKB/TrEMBL
  LTD UniProtKB/TrEMBL
PhenoGen Lmnb2 PhenoGen
PROSITE IF_ROD_2 UniProtKB/TrEMBL
  LTD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025742 RatGTEx
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/TrEMBL
  SSF74853 UniProtKB/TrEMBL
UniProt A0A8I5ZMS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPN1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A308_RAT UniProtKB/TrEMBL
  A0ABK0L756_RAT UniProtKB/TrEMBL
  A6K8E0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZLC1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Lmnb2  lamin B2  RGD1563803_predicted  similar to Lmnb2 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563803_predicted  similar to Lmnb2 protein (predicted)  LOC299625  similar to Lmnb2 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC299625  similar to Lmnb2 protein      Symbol and Name status set to provisional 70820 PROVISIONAL