Symbol:
Pcnp
Name:
PEST proteolytic signal containing nuclear protein
RGD ID:
1563775
Description:
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be active in nucleus. Orthologous to human PCNP (PEST proteolytic signal containing nuclear protein); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Ab2-416; liver regeneration-related protein LRRG084; LOC288165; PEST proteolytic signal-containing nuclear protein; PEST-containing nuclear protein; similar to PEST-containing nuclear protein
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 11 58,061,885 - 58,076,436 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 11 58,061,570 - 58,076,436 (+) Ensembl GRCr8 mRatBN7.2 11 44,592,766 - 44,607,372 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 11 44,592,742 - 44,607,348 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 11 53,369,115 - 53,383,652 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 11 46,030,729 - 46,045,266 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 11 45,154,893 - 45,169,429 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 11 47,055,641 - 47,070,319 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 11 47,061,354 - 47,068,648 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 11 50,237,656 - 50,252,209 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 11 45,572,442 - 45,580,616 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 11 44,348,073 - 44,356,228 (+) NCBI Celera Cytogenetic Map 11 q12 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Pcnp Rat (1->4)-beta-D-glucan multiple interactions ISO Pcnp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PCNP mRNA CTD PMID:36331819 Pcnp Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Pcnp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pcnp Rat 1,2-dichloroethane decreases expression ISO Pcnp (Mus musculus) 6480464 ethylene dichloride results in decreased expression of PCNP mRNA CTD PMID:28960355 Pcnp Rat 1,2-dimethylhydrazine multiple interactions ISO Pcnp (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PCNP mRNA CTD PMID:22206623 Pcnp Rat 1,2-dimethylhydrazine decreases expression ISO Pcnp (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of PCNP mRNA CTD PMID:22206623 Pcnp Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pcnp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pcnp Rat 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO PCNP (Homo sapiens) 6480464 [2,2',4,4'-tetrabromodiphenyl ether affects the methylation of PCNP gene] which affects the expression of PCNP mRNA CTD PMID:32653021 Pcnp Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Pcnp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pcnp Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Pcnp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pcnp Rat 2,6-dimethoxyphenol multiple interactions ISO PCNP (Homo sapiens) 6480464 [Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of PCNP protein; [Sodium more ... CTD PMID:38598786 Pcnp Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... CTD PMID:36041667 Pcnp Rat acetylsalicylic acid increases expression ISO PCNP (Homo sapiens) 6480464 Aspirin results in increased expression of PCNP mRNA CTD PMID:15928584 Pcnp Rat aflatoxin B1 increases expression ISO PCNP (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of PCNP mRNA CTD PMID:27153756 Pcnp Rat aristolochic acid A decreases expression ISO PCNP (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PCNP mRNA CTD PMID:33212167 Pcnp Rat arsenite(3-) multiple interactions ISO PCNP (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to PCNP mRNA] CTD PMID:32406909 Pcnp Rat benzatropine increases expression ISO PCNP (Homo sapiens) 6480464 Benztropine results in increased expression of PCNP protein CTD PMID:34122009 Pcnp Rat beta-lapachone increases expression ISO PCNP (Homo sapiens) 6480464 beta-lapachone results in increased expression of PCNP mRNA CTD PMID:38218311 Pcnp Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PCNP mRNA CTD PMID:25181051 Pcnp Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... CTD PMID:36041667 Pcnp Rat bisphenol A increases expression ISO PCNP (Homo sapiens) 6480464 bisphenol A results in increased expression of PCNP mRNA CTD PMID:33670352 Pcnp Rat bisphenol A decreases expression ISO Pcnp (Mus musculus) 6480464 bisphenol A results in decreased expression of PCNP mRNA CTD PMID:33221593 Pcnp Rat Bisphenol B increases expression ISO PCNP (Homo sapiens) 6480464 bisphenol B results in increased expression of PCNP protein CTD PMID:34186270 Pcnp Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... CTD PMID:36041667 Pcnp Rat Brodifacoum decreases expression EXP 6480464 bromfenacoum results in decreased expression of PCNP protein CTD PMID:28903499 Pcnp Rat cadmium atom increases expression ISO PCNP (Homo sapiens) 6480464 Cadmium results in increased expression of PCNP mRNA CTD PMID:24376830 Pcnp Rat cadmium dichloride decreases expression ISO PCNP (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of PCNP mRNA CTD PMID:38568856 Pcnp Rat caffeine decreases phosphorylation ISO PCNP (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of PCNP protein CTD PMID:35688186 Pcnp Rat chloropicrin affects expression ISO PCNP (Homo sapiens) 6480464 chloropicrin affects the expression of PCNP mRNA CTD PMID:26352163 Pcnp Rat choline multiple interactions ISO Pcnp (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 Pcnp Rat clofibrate increases expression ISO Pcnp (Mus musculus) 6480464 Clofibrate results in increased expression of PCNP mRNA CTD PMID:17585979 Pcnp Rat clozapine increases expression ISO PCNP (Homo sapiens) 6480464 Clozapine results in increased expression of PCNP protein CTD PMID:34122009 Pcnp Rat copper(II) sulfate decreases expression ISO PCNP (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of PCNP mRNA CTD PMID:19549813 Pcnp Rat cyclosporin A decreases expression ISO PCNP (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PCNP mRNA CTD PMID:25562108 Pcnp Rat dextran sulfate decreases expression ISO Pcnp (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of PCNP protein CTD PMID:32272095 Pcnp Rat dextran sulfate multiple interactions ISO Pcnp (Mus musculus) 6480464 Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PCNP protein] CTD PMID:32272095 Pcnp Rat dioxygen multiple interactions ISO Pcnp (Mus musculus) 6480464 [sulforaphane affects the susceptibility to Oxygen] which affects the expression of PCNP mRNA CTD PMID:30529165 Pcnp Rat diquat decreases expression ISO Pcnp (Mus musculus) 6480464 Diquat results in decreased expression of PCNP protein CTD PMID:36851058 Pcnp Rat diuron decreases expression ISO PCNP (Homo sapiens) 6480464 Diuron results in decreased expression of PCNP mRNA CTD PMID:35967413 Pcnp Rat erianin multiple interactions ISO Pcnp (Mus musculus) 6480464 Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PCNP protein] CTD PMID:32272095 Pcnp Rat ethanol affects splicing ISO Pcnp (Mus musculus) 6480464 Ethanol affects the splicing of PCNP mRNA CTD PMID:30319688 Pcnp Rat ethyl methanesulfonate increases expression ISO PCNP (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of PCNP mRNA CTD PMID:23649840 Pcnp Rat folic acid multiple interactions ISO Pcnp (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PCNP mRNA; [Methionine deficiency co-treated more ... CTD PMID:20938992|PMID:22206623 Pcnp Rat formaldehyde decreases expression ISO PCNP (Homo sapiens) 6480464 Formaldehyde results in decreased expression of PCNP mRNA CTD PMID:23649840 Pcnp Rat FR900359 affects phosphorylation ISO PCNP (Homo sapiens) 6480464 FR900359 affects the phosphorylation of PCNP protein CTD PMID:37730182 Pcnp Rat furfural multiple interactions ISO PCNP (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of PCNP protein CTD PMID:38598786 Pcnp Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PCNP mRNA CTD PMID:33387578 Pcnp Rat hexadecanoic acid decreases phosphorylation ISO PCNP (Homo sapiens) 6480464 Palmitic Acid results in decreased phosphorylation of PCNP protein CTD PMID:28073184 Pcnp Rat ivermectin decreases expression ISO PCNP (Homo sapiens) 6480464 Ivermectin results in decreased expression of PCNP protein CTD PMID:32959892 Pcnp Rat ketoconazole decreases expression ISO PCNP (Homo sapiens) 6480464 Ketoconazole results in decreased expression of PCNP mRNA CTD PMID:36621641 Pcnp Rat L-methionine multiple interactions ISO Pcnp (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 Pcnp Rat manganese atom multiple interactions ISO PCNP (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of PCNP more ... CTD PMID:39836092 Pcnp Rat manganese(0) multiple interactions ISO PCNP (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of PCNP more ... CTD PMID:39836092 Pcnp Rat manganese(II) chloride multiple interactions ISO PCNP (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of PCNP more ... CTD PMID:39836092 Pcnp Rat mercury dichloride decreases expression ISO PCNP (Homo sapiens) 6480464 Mercuric Chloride results in decreased expression of PCNP mRNA CTD PMID:27188386 Pcnp Rat methidathion decreases expression ISO Pcnp (Mus musculus) 6480464 methidathion results in decreased expression of PCNP mRNA CTD PMID:34813904 Pcnp Rat methyl methanesulfonate increases expression ISO PCNP (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of PCNP mRNA CTD PMID:23649840 Pcnp Rat ozone multiple interactions ISO PCNP (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of PCNP mRNA CTD PMID:35430440 Pcnp Rat paracetamol increases expression ISO PCNP (Homo sapiens) 6480464 Acetaminophen results in increased expression of PCNP mRNA CTD PMID:22230336 Pcnp Rat PCB138 multiple interactions ISO Pcnp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pcnp Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Pcnp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PCNP mRNA CTD PMID:36331819 Pcnp Rat propiconazole decreases expression ISO Pcnp (Mus musculus) 6480464 propiconazole results in decreased expression of PCNP mRNA CTD PMID:21278054 Pcnp Rat rotenone increases expression EXP 6480464 Rotenone results in increased expression of PCNP mRNA CTD PMID:19013527 Pcnp Rat sodium arsenite decreases expression ISO PCNP (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PCNP mRNA; sodium arsenite results in decreased expression more ... CTD PMID:38228842|PMID:38568856 Pcnp Rat sodium chloride multiple interactions ISO PCNP (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of PCNP protein; [Sodium Chloride co-treated more ... CTD PMID:38598786 Pcnp Rat sulforaphane multiple interactions ISO Pcnp (Mus musculus) 6480464 [sulforaphane affects the susceptibility to Oxygen] which affects the expression of PCNP mRNA CTD PMID:30529165 Pcnp Rat sunitinib increases expression ISO PCNP (Homo sapiens) 6480464 Sunitinib results in increased expression of PCNP mRNA CTD PMID:31533062 Pcnp Rat thimerosal decreases expression ISO PCNP (Homo sapiens) 6480464 Thimerosal results in decreased expression of PCNP mRNA CTD PMID:27188386 Pcnp Rat titanium dioxide increases methylation ISO Pcnp (Mus musculus) 6480464 titanium dioxide results in increased methylation of PCNP promoter CTD PMID:35295148 Pcnp Rat triphenyl phosphate affects expression ISO PCNP (Homo sapiens) 6480464 triphenyl phosphate affects the expression of PCNP mRNA CTD PMID:37042841 Pcnp Rat triptonide increases expression ISO Pcnp (Mus musculus) 6480464 triptonide results in increased expression of PCNP mRNA CTD PMID:33045310 Pcnp Rat valproic acid affects expression ISO PCNP (Homo sapiens) 6480464 Valproic Acid affects the expression of PCNP mRNA CTD PMID:25979313 Pcnp Rat valproic acid decreases expression ISO PCNP (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PCNP mRNA CTD PMID:23179753|PMID:27188386 Pcnp Rat vorinostat decreases expression ISO PCNP (Homo sapiens) 6480464 vorinostat results in decreased expression of PCNP mRNA CTD PMID:27188386