Kiaa1755 (KIAA1755 ortholog) - Rat Genome Database

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Gene: Kiaa1755 (KIAA1755 ortholog) Rattus norvegicus
Analyze
Symbol: Kiaa1755
Name: KIAA1755 ortholog
RGD ID: 1563354
Description: Orthologous to human KIAA1755 (KIAA1755); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC311592; RGD1563354; similar to hypothetical protein D630003M21; uncharacterized protein KIAA1755 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,270,476 - 167,305,337 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3167,192,612 - 167,304,240 (-)EnsemblGRCr8
mRatBN7.23146,850,558 - 146,884,238 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,850,557 - 146,884,871 (-)EnsemblmRatBN7.2
Rnor_6.03154,682,369 - 154,716,261 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,682,282 - 154,716,239 (-)Ensemblrn6Rnor6.0
Rnor_5.03160,889,775 - 160,923,691 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43148,911,549 - 148,936,434 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3145,551,958 - 145,585,630 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Kiaa1755
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,270,476 - 167,305,337 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3167,192,612 - 167,304,240 (-)EnsemblGRCr8
mRatBN7.23146,850,558 - 146,884,238 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,850,557 - 146,884,871 (-)EnsemblmRatBN7.2
Rnor_6.03154,682,369 - 154,716,261 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,682,282 - 154,716,239 (-)Ensemblrn6Rnor6.0
Rnor_5.03160,889,775 - 160,923,691 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43148,911,549 - 148,936,434 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3145,551,958 - 145,585,630 (-)NCBICelera
Cytogenetic Map3q42NCBI
KIAA1755
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,210,503 - 38,260,735 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,210,503 - 38,261,039 (-)Ensemblhg38GRCh38
GRCh372036,838,905 - 36,889,137 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,272,321 - 36,322,588 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2033,547,688 - 33,597,961 (-)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,575,996 - 33,626,528 (-)NCBIHuRef
CHM1_12036,742,595 - 36,792,858 (-)NCBICHM1_1
T2T-CHM13v2.02039,936,620 - 39,986,885 (-)NCBIT2T-CHM13v2.0
D630003M21Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,024,453 - 158,071,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2158,024,453 - 158,071,142 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382158,182,533 - 158,229,929 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,182,533 - 158,229,222 (-)Ensemblmm10GRCm38
MGSCv372158,008,269 - 158,054,958 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362157,887,192 - 157,920,663 (-)NCBIMGSCv36mm8
Celera2164,127,452 - 164,165,689 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
Kiaa1755
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544518,460,205 - 18,496,637 (+)Ensembl
ChiLan1.0NW_00495544518,461,126 - 18,497,134 (+)NCBIChiLan1.0ChiLan1.0
KIAA1755
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22143,936,756 - 43,985,404 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12043,929,870 - 43,978,461 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,536,041 - 34,584,652 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12035,646,173 - 35,696,042 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,646,743 - 35,695,769 (-)EnsemblpanPan2panpan1.1
KIAA1755
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,705,880 - 26,746,206 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,705,877 - 26,746,295 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2426,351,783 - 26,392,061 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02427,402,317 - 27,442,592 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,402,321 - 27,442,736 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,676,735 - 26,716,943 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,784,566 - 26,824,851 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,272,967 - 27,313,254 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kiaa1755
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,612,592 - 175,650,086 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,099,392 - 3,136,966 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,099,398 - 3,136,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIAA1755
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,275,505 - 41,329,143 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11741,275,501 - 41,321,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,681,171 - 46,715,759 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KIAA1755
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,490,719 - 25,540,750 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,504,610 - 25,540,756 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605074,331,043 - 74,379,849 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kiaa1755
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248421,405,394 - 1,444,144 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248421,405,407 - 1,443,755 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Kiaa1755
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15137,539,953 - 137,573,152 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kiaa1755
118 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:74
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000019453, ENSRNOT00000074976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3160357340167835660Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 148 91 90 59 72 59 6 336 172 11 127 81 92 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000019453   ⟹   ENSRNOP00000019453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,850,557 - 146,884,385 (-)Ensembl
Rnor_6.0 Ensembl3154,682,282 - 154,716,239 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112825   ⟹   ENSRNOP00000088583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,850,572 - 146,884,871 (-)Ensembl
RefSeq Acc Id: XM_006235462   ⟹   XP_006235524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83167,270,476 - 167,304,154 (-)NCBI
mRatBN7.23146,850,558 - 146,884,238 (-)NCBI
Rnor_6.03154,682,369 - 154,716,261 (-)NCBI
Rnor_5.03160,889,775 - 160,923,691 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235463   ⟹   XP_006235525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83167,270,476 - 167,305,337 (-)NCBI
mRatBN7.23146,850,558 - 146,884,238 (-)NCBI
Rnor_6.03154,682,369 - 154,716,260 (-)NCBI
Rnor_5.03160,889,775 - 160,923,691 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592275   ⟹   XP_017447764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83167,270,476 - 167,298,928 (-)NCBI
mRatBN7.23146,850,558 - 146,879,009 (-)NCBI
Rnor_6.03154,682,369 - 154,709,458 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006235524   ⟸   XM_006235462
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006235525   ⟸   XM_006235463
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447764   ⟸   XM_017592275
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A850 (UniProtKB/TrEMBL),   A6JWV3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019453   ⟸   ENSRNOT00000019453
Ensembl Acc Id: ENSRNOP00000088583   ⟸   ENSRNOT00000112825

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M4P5-F1-model_v2 AlphaFold F1M4P5 1-1198 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563354 AgrOrtholog
BioCyc Gene G2FUF-47036 BioCyc
Ensembl Genes ENSRNOG00000014424 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019453 ENTREZGENE
  ENSRNOT00000019453.7 UniProtKB/TrEMBL
  ENSRNOT00000112825 ENTREZGENE
  ENSRNOT00000112825.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.60 UniProtKB/TrEMBL
InterPro Rho_GEF_signaling-related UniProtKB/TrEMBL
KEGG Report rno:311592 UniProtKB/TrEMBL
NCBI Gene 311592 ENTREZGENE
PANTHER RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED UniProtKB/TrEMBL
  SIMILAR TO HYPOTHETICAL PROTEIN D630003M21 UniProtKB/TrEMBL
PhenoGen Kiaa1755 PhenoGen
RatGTEx ENSRNOG00000014424 RatGTEx
UniProt A0A8I6A850 ENTREZGENE, UniProtKB/TrEMBL
  A6JWV3 ENTREZGENE, UniProtKB/TrEMBL
  F1M4P5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-28 Kiaa1755  KIAA1755 ortholog  RGD1563354  similar to hypothetical protein D630003M21  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1563354  similar to hypothetical protein D630003M21   RGD1563354_predicted  similar to hypothetical protein D630003M21 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563354_predicted  similar to hypothetical protein D630003M21 (predicted)  LOC311592  similar to hypothetical protein D630003M21  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC311592  similar to hypothetical protein D630003M21      Symbol and Name status set to provisional 70820 PROVISIONAL