Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pdxdc1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Pdxdc1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PDXDC1 mRNA] | CTD | PMID:22206623 | Pdxdc1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of PDXDC1 mRNA | CTD | PMID:22206623 | Pdxdc1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of PDXDC1 mRNA | CTD | PMID:17555576 | Pdxdc1 | Rat | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Metribolone results in increased expression of PDXDC1 protein | CTD | PMID:17152098 | Pdxdc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PDXDC1 mRNA | CTD | PMID:21570461 | Pdxdc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PDXDC1 mRNA | CTD | PMID:32109520 | Pdxdc1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of PDXDC1 mRNA | CTD | PMID:39298647 | Pdxdc1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of PDXDC1 protein | CTD | PMID:34186270 | Pdxdc1 | Rat | acrolein | multiple interactions | ISO | PDXDC1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Pdxdc1 | Rat | aflatoxin B1 | decreases methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PDXDC1 gene; Aflatoxin B1 results in decreased methylation more ... | CTD | PMID:27153756|PMID:30157460 | Pdxdc1 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of PDXDC1 intron | CTD | PMID:30157460 | Pdxdc1 | Rat | all-trans-retinoic acid | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PDXDC1 mRNA | CTD | PMID:33167477 | Pdxdc1 | Rat | alpha-pinene | multiple interactions | ISO | PDXDC1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Pdxdc1 | Rat | arsenous acid | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PDXDC1 mRNA | CTD | PMID:22521957 | Pdxdc1 | Rat | avobenzone | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | avobenzone results in increased expression of PDXDC1 mRNA | CTD | PMID:31016361 | Pdxdc1 | Rat | benzo[a]pyrene | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PDXDC1 mRNA | CTD | PMID:22228805 | Pdxdc1 | Rat | benzo[a]pyrene | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PDXDC1 mRNA | CTD | PMID:32234424 | Pdxdc1 | Rat | benzo[a]pyrene | affects methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PDXDC1 intron | CTD | PMID:30157460 | Pdxdc1 | Rat | benzo[a]pyrene | decreases methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PDXDC1 3' UTR | CTD | PMID:27901495 | Pdxdc1 | Rat | benzo[e]pyrene | decreases methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of PDXDC1 intron | CTD | PMID:30157460 | Pdxdc1 | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of PDXDC1 mRNA | CTD | PMID:26377693 | Pdxdc1 | Rat | beta-lapachone | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of PDXDC1 mRNA | CTD | PMID:38218311 | Pdxdc1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PDXDC1 mRNA | CTD | PMID:25181051 | Pdxdc1 | Rat | bisphenol A | affects expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of PDXDC1 mRNA | CTD | PMID:30903817 | Pdxdc1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PDXDC1 mRNA | CTD | PMID:30816183|PMID:34947998 | Pdxdc1 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of PDXDC1 mRNA | CTD | PMID:33453195 | Pdxdc1 | Rat | caffeine | affects phosphorylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of PDXDC1 protein | CTD | PMID:35688186 | Pdxdc1 | Rat | carbon nanotube | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of PDXDC1 mRNA | CTD | PMID:25554681 | Pdxdc1 | Rat | clofibrate | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of PDXDC1 mRNA | CTD | PMID:17585979 | Pdxdc1 | Rat | copper(II) sulfate | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PDXDC1 mRNA | CTD | PMID:19549813 | Pdxdc1 | Rat | coumarin | affects phosphorylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of PDXDC1 protein | CTD | PMID:35688186 | Pdxdc1 | Rat | cyclosporin A | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PDXDC1 mRNA | CTD | PMID:25562108 | Pdxdc1 | Rat | diarsenic trioxide | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PDXDC1 mRNA | CTD | PMID:22521957 | Pdxdc1 | Rat | doxorubicin | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PDXDC1 mRNA | CTD | PMID:29803840 | Pdxdc1 | Rat | folic acid | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PDXDC1 mRNA | CTD | PMID:25629700 | Pdxdc1 | Rat | folic acid | multiple interactions | ISO | Pdxdc1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PDXDC1 mRNA] | CTD | PMID:22206623 | Pdxdc1 | Rat | glyphosate | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Glyphosate results in increased expression of PDXDC1 protein | CTD | PMID:36173347 | Pdxdc1 | Rat | GSK-J4 | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | GSK-J4 results in increased expression of PDXDC1 mRNA | CTD | PMID:29301935 | Pdxdc1 | Rat | hydrogen peroxide | multiple interactions | ISO | Pdxdc1 (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased phosphorylation of PDXDC1 protein | CTD | PMID:31494107 | Pdxdc1 | Rat | isoprenaline | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Isoproterenol results in decreased expression of PDXDC1 mRNA | CTD | PMID:20003209 | Pdxdc1 | Rat | ivermectin | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PDXDC1 protein | CTD | PMID:32959892 | Pdxdc1 | Rat | menadione | affects expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of PDXDC1 mRNA | CTD | PMID:20044591 | Pdxdc1 | Rat | methapyrilene | decreases methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of PDXDC1 intron | CTD | PMID:30157460 | Pdxdc1 | Rat | ochratoxin A | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | ochratoxin A results in increased expression of PDXDC1 protein | CTD | PMID:39638853 | Pdxdc1 | Rat | ozone | multiple interactions | ISO | PDXDC1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Pdxdc1 | Rat | paracetamol | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PDXDC1 mRNA | CTD | PMID:21420995 | Pdxdc1 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of PDXDC1 mRNA | CTD | PMID:37995155 | Pdxdc1 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of PDXDC1 mRNA | CTD | PMID:28903501 | Pdxdc1 | Rat | propiconazole | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | propiconazole results in increased expression of PDXDC1 mRNA | CTD | PMID:21278054 | Pdxdc1 | Rat | resveratrol | multiple interactions | ISO | PDXDC1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PDXDC1 mRNA | CTD | PMID:23557933 | Pdxdc1 | Rat | sodium arsenite | affects expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of PDXDC1 mRNA | CTD | PMID:29319823 | Pdxdc1 | Rat | sodium arsenite | decreases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PDXDC1 protein | CTD | PMID:30528433 | Pdxdc1 | Rat | sodium arsenite | multiple interactions | ISO | PDXDC1 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [PDXDC1 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | Pdxdc1 | Rat | sodium arsenite | increases expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PDXDC1 mRNA | CTD | PMID:38568856 | Pdxdc1 | Rat | tamoxifen | affects expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of PDXDC1 mRNA | CTD | PMID:17555576 | Pdxdc1 | Rat | testosterone | multiple interactions | ISO | Pdxdc1 (Mus musculus) | 6480464 | 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane inhibits the reaction [Testosterone deficiency results in decreased expression of PDXDC1 mRNA] | CTD | PMID:33848595 | Pdxdc1 | Rat | testosterone | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Testosterone deficiency results in decreased expression of PDXDC1 mRNA | CTD | PMID:33848595 | Pdxdc1 | Rat | titanium dioxide | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PDXDC1 mRNA | CTD | PMID:23557971|PMID:29128614|PMID:29264374 | Pdxdc1 | Rat | titanium dioxide | decreases methylation | ISO | Pdxdc1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PDXDC1 promoter | CTD | PMID:35295148 | Pdxdc1 | Rat | triphenyl phosphate | affects expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PDXDC1 mRNA | CTD | PMID:37042841 | Pdxdc1 | Rat | triptonide | increases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | triptonide results in increased expression of PDXDC1 mRNA | CTD | PMID:33045310 | Pdxdc1 | Rat | valproic acid | decreases methylation | ISO | PDXDC1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PDXDC1 gene | CTD | PMID:29154799 | Pdxdc1 | Rat | valproic acid | affects expression | ISO | PDXDC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PDXDC1 mRNA | CTD | PMID:25979313 | Pdxdc1 | Rat | zearalenone | decreases expression | ISO | Pdxdc1 (Mus musculus) | 6480464 | Zearalenone results in decreased expression of PDXDC1 protein | CTD | PMID:36252740 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















