Ubr1 (ubiquitin protein ligase E3 component n-recognin 1) - Rat Genome Database

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Gene: Ubr1 (ubiquitin protein ligase E3 component n-recognin 1) Rattus norvegicus
Analyze
Symbol: Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
RGD ID: 1562326
Description: Predicted to enable L-leucine binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular response to L-leucine; negative regulation of TOR signaling; and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome complex and ubiquitin ligase complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Johanson-Blizzard syndrome and cardiovascular system disease. Orthologous to human UBR1 (ubiquitin protein ligase E3 component n-recognin 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase UBR1; LOC499877; RGD1562326; similar to ubiquitin-protein ligase E3-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83128,265,160 - 128,377,830 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3128,265,115 - 128,375,671 (-)EnsemblGRCr8
mRatBN7.23107,813,721 - 107,921,701 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,811,392 - 107,922,204 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3111,487,521 - 111,595,462 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03120,083,088 - 120,191,024 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,743,477 - 117,851,413 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,800,557 - 112,910,038 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,800,557 - 112,876,773 (-)Ensemblrn6Rnor6.0
Rnor_5.03119,343,521 - 119,453,073 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43107,632,668 - 107,746,611 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3106,718,636 - 106,826,666 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
proteasome complex  (IEA,ISO)
ubiquitin ligase complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Johanson-Blizzard syndrome caused by identical UBR1 mutations in two unrelated girls, one with a cardiomyopathy. Elting M, etal., Am J Med Genet A. 2008 Dec 1;146A(23):3058-61. doi: 10.1002/ajmg.a.32566.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Recurrent Johanson-Blizzard syndrome in a triplet pregnancy complicated by urethral obstruction sequence: a clinical, molecular, and immunohistochemical approach. Schoner K, etal., Pediatr Dev Pathol. 2012 Jan-Feb;15(1):50-7. doi: 10.2350/11-04-1020-OA.1. Epub 2011 Jun 28.
7. Aberrantly Methylated-Differentially Expressed Genes Identify Novel Atherosclerosis Risk Subtypes. Xue Y, etal., Front Genet. 2020 Dec 14;11:569572. doi: 10.3389/fgene.2020.569572. eCollection 2020.
Additional References at PubMed
PMID:11689692   PMID:14585983   PMID:20298436   PMID:26514267   PMID:37094938  


Genomics

Comparative Map Data
Ubr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83128,265,160 - 128,377,830 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3128,265,115 - 128,375,671 (-)EnsemblGRCr8
mRatBN7.23107,813,721 - 107,921,701 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,811,392 - 107,922,204 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3111,487,521 - 111,595,462 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03120,083,088 - 120,191,024 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,743,477 - 117,851,413 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,800,557 - 112,910,038 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,800,557 - 112,876,773 (-)Ensemblrn6Rnor6.0
Rnor_5.03119,343,521 - 119,453,073 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43107,632,668 - 107,746,611 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3106,718,636 - 106,826,666 (-)NCBICelera
Cytogenetic Map3q35NCBI
UBR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,942,897 - 43,106,038 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1542,942,897 - 43,106,113 (-)Ensemblhg38GRCh38
GRCh371543,235,095 - 43,398,236 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361541,022,387 - 41,185,578 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341541,024,818 - 41,185,512NCBI
Celera1520,005,916 - 20,169,100 (-)NCBICelera
Cytogenetic Map15q15.2NCBI
HuRef1520,083,513 - 20,246,655 (-)NCBIHuRef
CHM1_11543,353,443 - 43,517,124 (-)NCBICHM1_1
T2T-CHM13v2.01540,750,009 - 40,913,326 (-)NCBIT2T-CHM13v2.0
Ubr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,690,753 - 120,801,246 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,690,750 - 120,801,196 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382120,860,272 - 120,970,760 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,860,269 - 120,970,715 (-)Ensemblmm10GRCm38
MGSCv372120,686,008 - 120,796,451 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362120,553,087 - 120,662,156 (-)NCBIMGSCv36mm8
Celera2121,999,127 - 122,120,067 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
Ubr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554169,572,171 - 9,731,453 (-)Ensembl
ChiLan1.0NW_0049554169,571,628 - 9,731,551 (-)NCBIChiLan1.0ChiLan1.0
UBR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21632,190,048 - 32,371,922 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11536,351,852 - 36,533,727 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,899,611 - 22,064,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11540,057,680 - 40,223,042 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1540,060,111 - 40,221,725 (-)EnsemblpanPan2panpan1.1
UBR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,869,769 - 10,006,994 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl309,870,021 - 10,006,947 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha309,926,950 - 10,066,799 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03010,005,751 - 10,143,458 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3010,005,841 - 10,143,085 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,920,878 - 10,060,694 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03010,043,912 - 10,181,675 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03010,161,091 - 10,301,368 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ubr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864088,324,766 - 88,475,149 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364716,171,593 - 6,313,937 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364716,171,655 - 6,313,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,319,311 - 128,474,302 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11128,319,311 - 128,474,330 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,202,498 - 143,318,189 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12639,851,630 - 40,026,817 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048100,976,727 - 101,133,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480410,036,225 - 10,225,571 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462480410,035,122 - 10,225,640 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ubr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1598,983,091 - 99,094,560 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ubr1
583 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:36
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000015086
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3122654702136118980Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)3125814931139636791Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
BE102818  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,844,350 - 107,844,531 (+)MAPPERmRatBN7.2
Rnor_6.03112,831,230 - 112,831,410NCBIRnor6.0
Rnor_5.03119,373,907 - 119,374,087UniSTSRnor5.0
RGSC_v3.43107,666,170 - 107,666,350UniSTSRGSC3.4
Celera3106,749,303 - 106,749,483UniSTS
RH 3.4 Map3944.4UniSTS
Cytogenetic Map3q35UniSTS
BF405998  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,844,909 - 107,845,063 (+)MAPPERmRatBN7.2
Rnor_6.03112,831,789 - 112,831,942NCBIRnor6.0
Rnor_5.03119,374,466 - 119,374,619UniSTSRnor5.0
RGSC_v3.43107,666,729 - 107,666,882UniSTSRGSC3.4
Celera3106,749,862 - 106,750,015UniSTS
RH 3.4 Map3944.4UniSTS
Cytogenetic Map3q35UniSTS
BF387584  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,817,324 - 107,817,493 (+)MAPPERmRatBN7.2
Rnor_6.03112,804,160 - 112,804,328NCBIRnor6.0
Rnor_5.03119,347,124 - 119,347,292UniSTSRnor5.0
RGSC_v3.43107,638,613 - 107,638,781UniSTSRGSC3.4
Celera3106,722,239 - 106,722,407UniSTS
RH 3.4 Map3948.2UniSTS
Cytogenetic Map3q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015086   ⟹   ENSRNOP00000015086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3128,265,115 - 128,375,671 (-)Ensembl
mRatBN7.2 Ensembl3107,811,392 - 107,888,440 (-)Ensembl
Rnor_6.0 Ensembl3112,800,557 - 112,876,773 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108697   ⟹   ENSRNOP00000084477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3128,265,115 - 128,375,671 (-)Ensembl
mRatBN7.2 Ensembl3107,811,392 - 107,922,204 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109471   ⟹   ENSRNOP00000076942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3128,265,115 - 128,372,024 (-)Ensembl
mRatBN7.2 Ensembl3107,811,392 - 107,911,366 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165786   ⟹   ENSRNOP00000100894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3128,265,115 - 128,375,671 (-)Ensembl
RefSeq Acc Id: NM_001178072   ⟹   NP_001171543
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83128,267,444 - 128,375,472 (-)NCBI
mRatBN7.23107,813,721 - 107,921,701 (-)NCBI
Rnor_6.03112,800,557 - 112,910,038 (-)NCBI
Rnor_5.03119,343,521 - 119,453,073 (-)NCBI
Celera3106,718,636 - 106,826,666 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063284367   ⟹   XP_063140437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83128,265,160 - 128,377,830 (-)NCBI
RefSeq Acc Id: XM_063284368   ⟹   XP_063140438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83128,265,160 - 128,347,711 (-)NCBI
RefSeq Acc Id: XM_063284369   ⟹   XP_063140439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83128,265,160 - 128,327,429 (-)NCBI
RefSeq Acc Id: NP_001171543   ⟸   NM_001178072
- UniProtKB: D5MTG9 (UniProtKB/TrEMBL),   A0A8I5ZZN6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015086   ⟸   ENSRNOT00000015086
Ensembl Acc Id: ENSRNOP00000084477   ⟸   ENSRNOT00000108697
Ensembl Acc Id: ENSRNOP00000076942   ⟸   ENSRNOT00000109471
RefSeq Acc Id: XP_063140437   ⟸   XM_063284367
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140438   ⟸   XM_063284368
- Peptide Label: isoform X2
- UniProtKB: D3ZQC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140439   ⟸   XM_063284369
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000100894   ⟸   ENSRNOT00000165786
Protein Domains
UBR-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQC6-F1-model_v2 AlphaFold D3ZQC6 1-1329 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562326 AgrOrtholog
BioCyc Gene G2FUF-48152 BioCyc
Ensembl Genes ENSRNOG00000037207 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015086 ENTREZGENE
  ENSRNOT00000015086.8 UniProtKB/TrEMBL
  ENSRNOT00000108697 ENTREZGENE
  ENSRNOT00000108697.2 UniProtKB/TrEMBL
  ENSRNOT00000109471.2 UniProtKB/TrEMBL
  ENSRNOT00000165786.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.110.30 UniProtKB/TrEMBL
  3.30.1390.10 UniProtKB/TrEMBL
InterPro ClpS_core UniProtKB/TrEMBL
  E3_ligase_UBR-like_C UniProtKB/TrEMBL
  Ribosomal_L7/12_C/ClpS-like UniProtKB/TrEMBL
  UBR-box_UBR1 UniProtKB/TrEMBL
  UBR1-like UniProtKB/TrEMBL
  UBR1-like_winged-helix UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
  Znf_N-recognin UniProtKB/TrEMBL
KEGG Report rno:499877 UniProtKB/TrEMBL
NCBI Gene 499877 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR1 UniProtKB/TrEMBL
  PTHR21497 UniProtKB/TrEMBL
Pfam ClpS UniProtKB/TrEMBL
  PRT6_C UniProtKB/TrEMBL
  UBR1-like_wing UniProtKB/TrEMBL
  zf-UBR UniProtKB/TrEMBL
PhenoGen Ubr1 PhenoGen
PROSITE ZF_UBR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000037207 RatGTEx
SMART ZnF_UBR1 UniProtKB/TrEMBL
Superfamily-SCOP Ribosomal_L7/12_C/ClpS-like UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A8I5ZK69_RAT UniProtKB/TrEMBL
  A0A8I5ZZN6 ENTREZGENE
  A0ABK0L990_RAT UniProtKB/TrEMBL
  D3ZQC6 ENTREZGENE, UniProtKB/TrEMBL
  D5MTG9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8I5ZZN6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 RGD1562326  similar to ubiquitin-protein ligase E3-alpha   RGD1562326_predicted  similar to ubiquitin-protein ligase E3-alpha (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562326_predicted  similar to ubiquitin-protein ligase E3-alpha (predicted)  LOC499877  similar to ubiquitin-protein ligase E3-alpha  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499877  similar to ubiquitin-protein ligase E3-alpha      Symbol and Name status set to provisional 70820 PROVISIONAL