Jam2 (junctional adhesion molecule 2) - Rat Genome Database

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Gene: Jam2 (junctional adhesion molecule 2) Rattus norvegicus
Analyze
Symbol: Jam2
Name: junctional adhesion molecule 2
RGD ID: 1561692
Description: Predicted to enable integrin binding activity. Predicted to be involved in several processes, including hematopoietic stem cell migration to bone marrow; leukocyte tethering or rolling; and negative regulation of myelination. Predicted to act upstream of or within negative regulation of cell adhesion. Predicted to be located in cell-cell contact zone and somatodendritic compartment. Predicted to be part of protein complex involved in cell adhesion. Predicted to be active in cell surface; plasma membrane; and tight junction. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human JAM2 (junctional adhesion molecule 2); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: junction adhesion molecule 2; junctional adhesion molecule B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,316,287 - 37,366,517 (+)NCBIGRCr8
mRatBN7.21123,830,820 - 23,880,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,831,106 - 23,880,063 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,537,340 - 32,586,308 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,237,747 - 25,286,715 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,426,449 - 24,475,421 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,235,310 - 24,285,279 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,266,345 - 24,285,275 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01127,864,652 - 27,913,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41124,310,704 - 24,315,219 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1123,670,522 - 23,719,259 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cannabidiol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
cytarabine  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzofurans  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
folic acid  (ISO)
fonofos  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
mercaptopurine  (EXP)
mercury dibromide  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
naphthalene  (EXP)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
purine-6-thiol  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
sotorasib  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
tributylstannane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. Ludwig RJ, etal., J Invest Dermatol. 2005 Nov;125(5):969-76.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11590146   PMID:11823489   PMID:12070135   PMID:12239159   PMID:15372036   PMID:16093349   PMID:19740376   PMID:24357068   PMID:27499083  


Genomics

Comparative Map Data
Jam2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,316,287 - 37,366,517 (+)NCBIGRCr8
mRatBN7.21123,830,820 - 23,880,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,831,106 - 23,880,063 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,537,340 - 32,586,308 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,237,747 - 25,286,715 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,426,449 - 24,475,421 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,235,310 - 24,285,279 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,266,345 - 24,285,275 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01127,864,652 - 27,913,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41124,310,704 - 24,315,219 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1123,670,522 - 23,719,259 (+)NCBICelera
Cytogenetic Map11q11NCBI
JAM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382125,639,258 - 25,717,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2125,639,258 - 25,717,562 (+)EnsemblGRCh38hg38GRCh38
GRCh372127,011,570 - 27,089,874 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362125,933,460 - 26,009,106 (+)NCBINCBI36Build 36hg18NCBI36
Build 342125,933,459 - 26,009,106NCBI
Celera2112,195,003 - 12,270,650 (+)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2112,414,742 - 12,493,008 (+)NCBIHuRef
CHM1_12126,572,234 - 26,650,529 (+)NCBICHM1_1
T2T-CHM13v2.02123,996,799 - 24,075,106 (+)NCBIT2T-CHM13v2.0
Jam2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,571,011 - 84,623,268 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1684,571,011 - 84,622,816 (+)EnsemblGRCm39 Ensembl
GRCm381684,774,123 - 84,826,380 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,774,123 - 84,825,928 (+)EnsemblGRCm38mm10GRCm38
MGSCv371684,774,368 - 84,823,129 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361684,657,025 - 84,707,359 (+)NCBIMGSCv36mm8
Celera1684,978,233 - 85,028,276 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1646.92NCBI
Jam2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540725,571,570 - 25,599,551 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540725,531,891 - 25,599,551 (+)NCBIChiLan1.0ChiLan1.0
JAM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22221,832,762 - 21,912,523 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12116,690,714 - 16,769,718 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02112,084,083 - 12,162,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12125,442,054 - 25,518,987 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2125,441,765 - 25,519,304 (+)Ensemblpanpan1.1panPan2
JAM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13121,137,378 - 21,198,278 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3121,137,363 - 21,197,668 (+)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3121,194,569 - 21,197,958 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03121,191,218 - 21,252,072 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3121,191,320 - 21,253,587 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13121,209,766 - 21,270,172 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03121,210,940 - 21,271,401 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03121,686,386 - 21,746,819 (+)NCBIUU_Cfam_GSD_1.0
Jam2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497121,697,079 - 21,751,432 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366401,929,255 - 1,984,872 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366401,930,450 - 1,984,438 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,165,975 - 189,275,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,199,789 - 189,275,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,074,626 - 199,167,813 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JAM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1266,557,271 - 66,635,937 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl266,559,820 - 66,635,339 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605086,918,147 - 86,997,127 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jam2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474513,704,652 - 13,776,172 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474513,704,031 - 13,778,749 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Jam2
91 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:356
Count of miRNA genes:234
Interacting mature miRNAs:268
Transcripts:ENSRNOT00000046973
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111897620824697116Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111283104625121472Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat

Markers in Region
BF387369  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,861,495 - 23,861,668 (+)MAPPERmRatBN7.2
Rnor_6.01124,266,715 - 24,266,887NCBIRnor6.0
Rnor_5.01127,894,504 - 27,894,676UniSTSRnor5.0
Celera1123,700,703 - 23,700,875UniSTS
RH 3.4 Map11113.0UniSTS
Cytogenetic Map11q11UniSTS
RH130790  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,879,704 - 23,879,909 (+)MAPPERmRatBN7.2
Rnor_6.01124,284,917 - 24,285,121NCBIRnor6.0
Rnor_5.01127,912,913 - 27,913,117UniSTSRnor5.0
RGSC_v3.41124,314,857 - 24,315,061UniSTSRGSC3.4
Celera1123,718,897 - 23,719,101UniSTS
RH 3.4 Map11105.9UniSTS
Cytogenetic Map11q11UniSTS
RH131165  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,833,877 - 23,834,085 (+)MAPPERmRatBN7.2
Rnor_6.01124,238,082 - 24,238,289NCBIRnor6.0
Rnor_5.01127,867,424 - 27,867,631UniSTSRnor5.0
Celera1123,673,294 - 23,673,501UniSTS
RH 3.4 Map11102.3UniSTS
Cytogenetic Map11q11UniSTS
RH133736  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,878,718 - 23,878,928 (+)MAPPERmRatBN7.2
Rnor_6.01124,283,931 - 24,284,140NCBIRnor6.0
Rnor_5.01127,911,927 - 27,912,136UniSTSRnor5.0
RGSC_v3.41124,313,871 - 24,314,080UniSTSRGSC3.4
Celera1123,717,911 - 23,718,120UniSTS
RH 3.4 Map11108.1UniSTS
Cytogenetic Map11q11UniSTS
RH143705  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,877,444 - 23,877,563 (+)MAPPERmRatBN7.2
Rnor_6.01124,282,657 - 24,282,775NCBIRnor6.0
Rnor_5.01127,910,653 - 27,910,771UniSTSRnor5.0
RGSC_v3.41124,312,597 - 24,312,715UniSTSRGSC3.4
Celera1123,716,637 - 23,716,755UniSTS
RH 3.4 Map1199.2UniSTS
Cytogenetic Map11q11UniSTS
BE117177  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,841,327 - 23,841,526 (+)MAPPERmRatBN7.2
Rnor_6.01124,245,530 - 24,245,728NCBIRnor6.0
Rnor_5.01127,874,872 - 27,875,070UniSTSRnor5.0
Celera1123,680,742 - 23,680,940UniSTS
Cytogenetic Map11q11UniSTS
JAM2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,876,888 - 23,877,010 (+)MAPPERmRatBN7.2
Rnor_6.01124,282,101 - 24,282,222NCBIRnor6.0
Rnor_5.01127,910,097 - 27,910,218UniSTSRnor5.0
RGSC_v3.41124,312,041 - 24,312,162UniSTSRGSC3.4
Celera1123,716,081 - 23,716,202UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 35 20 5 18 5 7 8 74 24 36 11 7
Low 1 8 37 36 1 36 1 3 11 5 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000046973   ⟹   ENSRNOP00000049564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1123,831,106 - 23,880,063 (+)Ensembl
Rnor_6.0 Ensembl1124,266,345 - 24,285,275 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094504   ⟹   ENSRNOP00000092709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1123,860,422 - 23,880,063 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119888   ⟹   ENSRNOP00000096179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1123,856,161 - 23,871,223 (+)Ensembl
RefSeq Acc Id: NM_001034004   ⟹   NP_001029176
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,317,560 - 37,366,517 (+)NCBI
mRatBN7.21123,831,106 - 23,880,067 (+)NCBI
Rnor_6.01124,235,310 - 24,285,279 (+)NCBI
Rnor_5.01127,864,652 - 27,913,275 (+)NCBI
RGSC_v3.41124,310,704 - 24,315,219 (+)RGD
Celera1123,670,522 - 23,719,259 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088608   ⟹   XP_038944536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,316,287 - 37,366,517 (+)NCBI
mRatBN7.21123,830,820 - 23,880,071 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001029176   ⟸   NM_001034004
- Peptide Label: precursor
- UniProtKB: Q3MHC0 (UniProtKB/TrEMBL),   F1M065 (UniProtKB/TrEMBL),   A6JL57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000049564   ⟸   ENSRNOT00000046973
RefSeq Acc Id: XP_038944536   ⟸   XM_039088608
- Peptide Label: isoform X1
- UniProtKB: A6JL57 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096179   ⟸   ENSRNOT00000119888
RefSeq Acc Id: ENSRNOP00000092709   ⟸   ENSRNOT00000094504
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M065-F1-model_v2 AlphaFold F1M065 1-257 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561692 AgrOrtholog
BioCyc Gene G2FUF-22083 BioCyc
Ensembl Genes ENSRNOG00000042848 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046973 ENTREZGENE
  ENSRNOT00000046973.6 UniProtKB/TrEMBL
  ENSRNOT00000094504.1 UniProtKB/TrEMBL
  ENSRNOT00000119888.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192610 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  JAM2 UniProtKB/TrEMBL
KEGG Report rno:619374 UniProtKB/TrEMBL
MGC_CLONE MGC:124988 IMAGE-MGC_LOAD
NCBI Gene 619374 ENTREZGENE
PANTHER JUNCTIONAL ADHESION MOLECULE B UniProtKB/TrEMBL
  PTHR44663 UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Jam2 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042848 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I6AEF6_RAT UniProtKB/TrEMBL
  A0A8I6ANZ9_RAT UniProtKB/TrEMBL
  A6JL57 ENTREZGENE, UniProtKB/TrEMBL
  A6JL58_RAT UniProtKB/TrEMBL
  F1M065 ENTREZGENE
  Q3MHC0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1M065 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-06 Jam2  junctional adhesion molecule 2  Jam2  junction adhesion molecule 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Jam2  junction adhesion molecule 2      Symbol and Name status set to provisional 70820 PROVISIONAL