Zdhhc9 (zDHHC palmitoyltransferase 9) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Zdhhc9 (zDHHC palmitoyltransferase 9) Rattus norvegicus
Analyze
Symbol: Zdhhc9
Name: zDHHC palmitoyltransferase 9 (Ensembl:zinc finger DHHC-type palmitoyltransferase 9)
RGD ID: 1561389
Description: Predicted to enable Ras palmitoyltransferase activity. Predicted to be involved in host-mediated activation of viral process; positive regulation of defense response; and protein targeting to membrane. Predicted to act upstream of or within several processes, including cGAS/STING signaling pathway; non-canonical inflammasome complex assembly; and proteolysis involved in protein catabolic process. Predicted to be located in Golgi membrane. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Orthologous to human ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC302808; membrane-associated DHHC9 zinc finger protein; palmitoyltransferase ZDHHC9; zinc finger DHHC-type palmitoyltransferase 9; zinc finger, DHHC domain containing 9; zinc finger, DHHC-type containing 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X132,230,243 - 132,266,139 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX132,230,245 - 132,266,139 (-)EnsemblGRCr8
mRatBN7.2X127,352,340 - 127,388,245 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,352,345 - 127,388,245 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX129,478,111 - 129,514,060 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X133,048,918 - 133,084,810 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X130,575,263 - 130,611,214 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X135,005,171 - 135,041,207 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,005,123 - 135,041,027 (-)Ensemblrn6Rnor6.0
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X134,537,438 - 134,573,364 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX126,302,789 - 126,338,662 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16000296   PMID:16647879   PMID:23034182  


Genomics

Comparative Map Data
Zdhhc9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X132,230,243 - 132,266,139 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX132,230,245 - 132,266,139 (-)EnsemblGRCr8
mRatBN7.2X127,352,340 - 127,388,245 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,352,345 - 127,388,245 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX129,478,111 - 129,514,060 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X133,048,918 - 133,084,810 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X130,575,263 - 130,611,214 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X135,005,171 - 135,041,207 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,005,123 - 135,041,027 (-)Ensemblrn6Rnor6.0
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X134,537,438 - 134,573,364 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX126,302,789 - 126,338,662 (-)NCBICelera
Cytogenetic MapXq36NCBI
ZDHHC9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X129,803,288 - 129,843,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX129,803,288 - 129,844,215 (-)Ensemblhg38GRCh38
GRCh37X128,937,264 - 128,977,862 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X128,766,593 - 128,805,554 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X128,664,449 - 128,703,408NCBI
CeleraX129,323,767 - 129,364,414 (-)NCBICelera
Cytogenetic MapXq26.1NCBI
HuRefX118,338,764 - 118,378,757 (-)NCBIHuRef
CHM1_1X128,848,613 - 128,889,262 (-)NCBICHM1_1
T2T-CHM13v2.0X128,122,064 - 128,162,666 (-)NCBIT2T-CHM13v2.0
Zdhhc9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X47,260,844 - 47,297,792 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX47,260,846 - 47,297,755 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X48,171,967 - 48,208,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX48,171,969 - 48,208,878 (-)Ensemblmm10GRCm38
MGSCv37X45,525,148 - 45,561,879 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X44,416,598 - 44,453,310 (-)NCBIMGSCv36mm8
CeleraX35,674,299 - 35,710,725 (-)NCBICelera
Cytogenetic MapXA4NCBI
cM MapX25.55NCBI
Zdhhc9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554735,174,563 - 5,208,767 (+)Ensembl
ChiLan1.0NW_0049554735,174,575 - 5,208,767 (+)NCBIChiLan1.0ChiLan1.0
ZDHHC9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X129,228,185 - 129,266,847 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X129,230,131 - 129,270,455 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X118,932,986 - 118,973,238 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X129,230,556 - 129,270,665 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX129,230,571 - 129,270,665 (-)EnsemblpanPan2panpan1.1
ZDHHC9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,011,072 - 101,096,394 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX100,996,607 - 101,043,228 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX87,184,996 - 87,270,387 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X102,862,545 - 102,948,146 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX102,864,567 - 102,896,674 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X100,280,828 - 100,366,232 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,127,017 - 102,212,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X101,904,811 - 101,990,352 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Zdhhc9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X99,244,189 - 99,275,735 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364791,711,713 - 1,741,167 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364791,711,756 - 1,743,306 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZDHHC9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX106,401,245 - 106,436,014 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X106,397,139 - 106,436,103 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X122,170,189 - 122,205,037 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZDHHC9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X105,082,531 - 105,120,802 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606542,495,912 - 42,536,963 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zdhhc9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247979,023,833 - 9,060,855 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247979,027,316 - 9,060,321 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Zdhhc9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X110,201,898 - 110,237,261 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zdhhc9
112 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:723
Count of miRNA genes:287
Interacting mature miRNAs:375
Transcripts:ENSRNOT00000006484
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X120028026141353710Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X120028026141353710Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006484   ⟹   ENSRNOP00000006484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX132,230,245 - 132,266,139 (-)Ensembl
mRatBN7.2 EnsemblX127,352,345 - 127,388,245 (-)Ensembl
Rnor_6.0 EnsemblX135,005,123 - 135,041,027 (-)Ensembl
RefSeq Acc Id: NM_001039016   ⟹   NP_001034105
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X132,230,243 - 132,266,139 (-)NCBI
mRatBN7.2X127,352,343 - 127,388,245 (-)NCBI
Rnor_6.0X135,005,171 - 135,040,996 (-)NCBI
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBI
RGSC_v3.4X134,537,438 - 134,573,364 (-)RGD
CeleraX126,302,789 - 126,338,662 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257521   ⟹   XP_006257583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X132,230,243 - 132,265,930 (-)NCBI
mRatBN7.2X127,352,340 - 127,387,957 (-)NCBI
Rnor_6.0X135,005,171 - 135,040,730 (-)NCBI
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034105 (Get FASTA)   NCBI Sequence Viewer  
  XP_006257583 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI29071 (Get FASTA)   NCBI Sequence Viewer  
  AAX73388 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006484
  ENSRNOP00000006484.7
RefSeq Acc Id: NP_001034105   ⟸   NM_001039016
- UniProtKB: A1L1I1 (UniProtKB/TrEMBL),   F7F533 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257583   ⟸   XM_006257521
- Peptide Label: isoform X1
- UniProtKB: Q2TGJ9 (UniProtKB/TrEMBL),   F7F533 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006484   ⟸   ENSRNOT00000006484
Protein Domains
Palmitoyltransferase DHHC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2TGJ9-F1-model_v2 AlphaFold Q2TGJ9 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702010
Promoter ID:EPDNEW_R12534
Type:initiation region
Name:Zdhhc9_1
Description:zinc finger, DHHC-type containing 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X135,041,012 - 135,041,072EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561389 AgrOrtholog
BioCyc Gene G2FUF-1138 BioCyc
Ensembl Genes ENSRNOG00000004581 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006484 ENTREZGENE
  ENSRNOT00000006484.8 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7461054 IMAGE-MGC_LOAD
InterPro PFA4/ZDH16/20/ERF2-like UniProtKB/TrEMBL
  Znf_DHHC UniProtKB/TrEMBL
KEGG Report rno:302808 UniProtKB/TrEMBL
MGC_CLONE MGC:156472 IMAGE-MGC_LOAD
NCBI Gene 302808 ENTREZGENE
PANTHER PTHR22883:SF71 UniProtKB/TrEMBL
  ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam zf-DHHC UniProtKB/TrEMBL
PhenoGen Zdhhc9 PhenoGen
PROSITE DHHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004581 RatGTEx
UniProt A1L1I1 ENTREZGENE, UniProtKB/TrEMBL
  F7F533 ENTREZGENE
  Q2TGJ9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7F533 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Zdhhc9  zDHHC palmitoyltransferase 9  Zdhhc9  zinc finger DHHC-type palmitoyltransferase 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-11-11 Zdhhc9  zinc finger DHHC-type palmitoyltransferase 9  Zdhhc9  zinc finger, DHHC-type containing 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-17 Zdhhc9  zinc finger, DHHC-type containing 9  Zdhhc9  zinc finger, DHHC domain containing 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Zdhhc9  zinc finger, DHHC domain containing 9  LOC302808  membrane-associated DHHC9 zinc finger protein  Symbol and Name updated 1299863 APPROVED
2006-02-09 LOC302808  membrane-associated DHHC9 zinc finger protein      Symbol and Name status set to provisional 70820 PROVISIONAL