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Gene: Etaa1 (ETAA1 activator of ATR kinase) Rattus norvegicus

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Symbol:

Etaa1 (Ensembl: Etaa1-ps1)

Name:

ETAA1 activator of ATR kinase (Ensembl:ETAA1 activator of ATR kinase, pseudogene 1)

RGD ID:

1560957

Description:

Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in DNA damage response; regulation of DNA damage checkpoint; and replication fork processing. Predicted to act upstream of or within G2/M transition of mitotic cell cycle and mitotic G2/M transition checkpoint. Predicted to be active in nuclear replication fork. Orthologous to human ETAA1 (ETAA1 activator of ATR kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Etaa1l1; Ewing tumor-associated antigen 1; Ewing tumor-associated antigen 1-like 1; Ewing's tumor-associated antigen 1; ewing's tumor-associated antigen 1 homolog; LOC103693794; LOC498420; RGD1560957; similar to ETAA16 protein; similar to RIKEN cDNA 5730466H23

RGD Orthologs

Human

Mouse

Black Rat

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ETAA1 (ETAA1 activator of ATR kinase)	RGD	RGD
Mus musculus (house mouse):	Etaa1 (Ewing tumor-associated antigen 1)	RGD	RGD
Rattus rattus (black rat):	Etaa1 (ETAA1 activator of ATR kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Etaa1 (Ewing tumor-associated antigen 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ETAA1 (ETAA1 activator of ATR kinase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	etaa1b	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	etaa1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

Etaa1-ps1

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	96,500,899 - 96,515,617 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	96,500,899 - 96,517,796 (-)	Ensembl				GRCr8
mRatBN7.2	14	92,298,461 - 92,314,044 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	92,299,553 - 92,314,104 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	96,598,264 - 96,612,991 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	97,842,571 - 97,857,298 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	94,307,596 - 94,322,323 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	97,196,079 - 97,199,067 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	14	96,994,880 - 96,997,282 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	14	100,886,177 - 100,886,881 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	98,807,365 - 98,822,369 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	91,335,388 - 91,349,568 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pancreatic cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin M1 (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

folic acid (ISO)

FR900359 (ISO)

iron dichloride (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

okadaic acid (ISO)

p-chloromercuribenzoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenethyl isothiocyanate (EXP)

phenobarbital (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

Salinomycin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

testosterone (ISO)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IBA,ISO)

mitotic G2/M transition checkpoint (ISO)

positive regulation of protein serine/threonine kinase activity (ISO)

regulation of DNA damage checkpoint (IBA,ISO)

replication fork processing (IBA,ISO)

Cellular Component

nuclear replication fork (IBA,ISO)

nuclear speck (ISO)

nucleoplasm (ISO)

Molecular Function

protein binding (ISO)

protein serine/threonine kinase activator activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Etaa1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	96,500,899 - 96,515,617 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	96,500,899 - 96,517,796 (-)	Ensembl				GRCr8
mRatBN7.2	14	92,298,461 - 92,314,044 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	92,299,553 - 92,314,104 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	96,598,264 - 96,612,991 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	97,842,571 - 97,857,298 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	94,307,596 - 94,322,323 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	97,196,079 - 97,199,067 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	14	96,994,880 - 96,997,282 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	14	100,886,177 - 100,886,881 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	98,807,365 - 98,822,369 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	91,335,388 - 91,349,568 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

ETAA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	67,397,333 - 67,412,089 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	67,397,322 - 67,412,089 (+)	Ensembl			hg38	GRCh38
GRCh37	2	67,624,465 - 67,639,221 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	67,477,946 - 67,491,037 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	67,473,171 - 67,486,260 (+)	NCBI		Celera
Cytogenetic Map	2	p14	NCBI
HuRef	2	67,362,342 - 67,375,379 (+)	NCBI		HuRef
CHM1_1	2	67,555,586 - 67,568,671 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	67,407,046 - 67,421,800 (+)	NCBI		T2T-CHM13v2.0

Etaa1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	17,888,753 - 17,903,875 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	17,888,756 - 17,903,875 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	17,938,753 - 17,953,875 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	17,938,756 - 17,953,875 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	17,838,752 - 17,853,878 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	17,839,895 - 17,853,851 (-)	NCBI		MGSCv36	mm8
Celera	11	20,118,628 - 20,133,382 (-)	NCBI		Celera
Cytogenetic Map	11	A3.1	NCBI
cM Map	11	10.44	NCBI

Etaa1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	86,322,721 - 86,337,233 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Etaa1
218 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631213	Bw60	Body weight QTL60	4.51		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	84164970	100078267	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	59848686	104848686	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	77914838	104348525	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	74255551	109089856	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	77640071	96755654	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	62398852	107398852	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	100078267	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	60854936	105854936	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	74255551	109089856	Rat
4889951	Bss92	Bone structure and strength QTL 92	3.9		tibia area (VT:1000281)	tibia-fibula cortical bone total cross-sectional area (CMO:0001721)	14	86271332	100078267	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	77640071	96755654	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	59848686	104848686	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42616258	99224555	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	65920283	99224555	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	18	52	67	138	95	11	51	36	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC062001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000008135 ⟹ ENSRNOP00000008135

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	92,299,553 - 92,314,104 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097260 ⟹ ENSRNOP00000093008

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	92,299,553 - 92,313,696 (-)	Ensembl

RefSeq Acc Id:

NM_001109094 ⟹ NP_001102564

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	96,500,899 - 96,515,617 (-)	NCBI
mRatBN7.2	14	92,299,314 - 92,314,032 (-)	NCBI
Rnor_6.0	14	97,196,079 - 97,199,067 (-)	NCBI
Rnor_5.0	14	100,886,177 - 100,886,881 (-)	NCBI
RGSC_v3.4	14	98,807,365 - 98,822,369 (-)	RGD
Celera	14	91,335,388 - 91,349,568 (-)	RGD

Sequence:

show sequence

CGACTTGCAAAGATGGCGGTGATCGGTGGCGCGCGGCCTCTTAGCGGAGCGGTTGTCCCGCTCC
TCCGTAGCAAGATGTGAATGCGGCTGAAGGACGGTGCCACGGGAATGAGTCGGCGAAGGAAGCA
TGCGGACAGCCCTGTGCGGACGCGCAGGGCGGGTGCCGAGAACTGCTGCTCGGCAGCGGAACTG
TGGCCCCGGGCGTCCAGGGCGGCCCGCAGCTCCCAGCCCAGCCGGGCGGGAACGCGGTCTGCGC
TGCGGTCGCAACGGCGGGCAGCGGCTGACGGCGGGCGGAGCCCGGGGGAAAAGGAGACACCAAC
ACAAGTTCTGAAAGTGAATTTATTGTCCTGTACCTTCAGTTCTCCAAATGATCCAGATGGACAG
ACTGATATCTTCTGGGATCAAAATTCTCCAATGACAAAACAGTTAGGTAAAAGAAGAACAAAGC
GGATTTCCAGTGCATACAGTGATGAGATTTCACATATTGTTAATCGTATTGCTCCTCAGGATGA
AAAACCAGTGACAAACTCCATGCTGGGTGTATGGATTGGTGACACTGCTATTCCTTGTACTCCT
AGTGTTGCAAAAGAAAAGTCAAGAGTGAAAATCAGCTGCACAAAGTTAAAAACAAAAAATCGAG
AAAAAGAACTTATGAAATTGGCCCAACAGTTTGATAAAAATATGGAAGAACTTGATGTGATTCA
AGAGCAAGATGGGAAGAATCATGATTTTATCCAGATGACTTCAGAAATGGGACATTTACATAAC
CATAAAAATTCTGTGCAGATGGCATCAGATGATATAGTTCCTGAAGTCAGTTATACTCCAATAA
AGAAGCAAGTGGAGGGAGACAGCAGAATATCTCTGGGAAAGGGGCAAGACAGCAGTCAGAGACC
CTTTGACCGAAATGTTGAAGCAGCCTTTAATGCTATTTTTGATGGTTCCACTCAGATGTGTAGT
GGACAGCTAAGCCAGGAGCTGTCAGATACTTTTTTGAACAATAGTAAAACTTCCATGAAAAAGG
AAAATGTCTTACTACAAGAGGAAATCATTACTACTGAAACTCTGCTCACAGACAACCTGCTAAA
TAAAACTCCAATATCATCTTCCCCTCAAGTAGATACTACCATAATACTAAAATCATGTGTGACT
CCCAGTCCTAAGACTCCAGTAGCACCTAATAAGCATCTTGATGAATTGACTGCTAATGATTTTG
AGGATGATTGGGAAAGCTTACTAAGCAGTGAACCCTTCCTTATGGAGAATGCTGAAATGCTTGA
ACTCTTTCCCTCTACAACTGCTCAAGGTACTGGTCAGAAGGCAGTTTGTACCTCCATTGGGGAA
AATGATACAATCACATCAAGAGCAAATATGAATCTAGGTGGAAGGTTAAGAGACTCAAAAGTAA
CACTGGATCTTCCTTCAAAGACACGAAGCAGAGAACTAAAAAATGCTGGAGAATGTAGGTTTTC
ACCACATCCAGGTGATGAACCAAGGAAGTTCCCATTCATTGGGAATAAAGTGAGGTTTGAGAAA
TCTGTCACTAACTTTGTTAGTAAAAATGAAGATTATGTTGCTGTCTCTAACCTTACAAAAGTGA
AAGAAGATGGTCATGGTAAGGGCATACTTAATGCCTCTAACAAGTCTGTTTCATACACAAGGTA
TCCTAATGAACAAAATCACAAGCTTGGTGTTAACCTGCCTTTGAAAGTACCCACTACTGACCCA
TTTGATTCTGTGTTCGTGGGCAAAGAAAACATTGTGTGTAACACAAATCAGTCTCATGGATCAA
AGTTCAGTTCTCCCTTTGATGACTGGAATGACCCACTGTTGGCCAGTGAAATGATTAAAGCATG
CCATCAATTAGAAACTACCTGGGAAGCAGATGATGTAGATGATGATTTGTTATATCAGGCTTGT
GATGACATCGAAAGACTAACTCAGCAAGAAAACAAGGGCAGCAAGGAGTCAGAAAGTAAAAGTA
ATACTTCCATACATGGATCCAGAAATACTTGTTCTGCATCTGAACAAGGAAGTCAGTTGGTGTC
GTCTAAACATTGGAATCTTGTCAGTTCTCCAATGCCATTGTCTTTAACAAATAAATCACAGATA
AATAAGCCAGTGACAGTAGAGAAAAGAAACATATGTGGAGATTGTCCCAATATTTTGGATGCTA
CAAATTTGTCTGTGTGCTCTAAGAATTCAAGTGATAATCAGCATGTACCAGTACAGGTGAATAG
CTCAAACTCTGTTCTTGTAGGAAGTTCACATCTGAAAGTTAATTTGGGTCCTGTGAGCACAAAG
ATCGCTACTAATACGAAGTTTAGTACTGCTCAGCTGTCCCACCACAGCTTAGCAGATACAGCTC
AGAGTGACAGCAAAATACTGAAGTCATCAAAATTCACATTTAAAAAGAAGAACCCTCAGTTTCT
TTCTGAGTTAAATCAAAATCCTCTAGCAGGAAGTATGCCTGTTAGTAAAATCTCACAGGACTTA
GGAAAAAGGGAAACTGTCAATTCATGGCCTGAAGCTAATCAAAAACATTCTGAGTCTTTGAAAC
CATCTTCCCCAGACGAAGAAGAGAGAAACAGGAAGTATTCTCCTGAAGAAATTCGGCGGAAAAG
GCAGGAAGCACTGGTTCGAAGAAAGGCCAAAGCGTTGCACACTGTGCAGTCAGCTCCTGTTTCA
CTGCCTTGGTGAAAGCCGAGTGAGCCGGTTTGACAGCTGTGAGAACTATCTGTGATAGGACTTC
GTTCTGATTTCTCCGTGAGAAGTTTACTGCTGAGTTTTTAGCATGAGCTACTTTATTATTTAAT
AAATCACTGTTTACAATGGTAAATGAAACCTTCTCATATGTATGTGAATCATGTATATAAGTTT
TTGAAAAGTTAGCAGTTATGTATATACAGAGGAAAAGTACTTGTCTTTATAAATAGGGTAGCAG
ATGAGCATCAAAATAACTGTATAGCTTCTGTAGAAGACTTTTTCTAGCACAAATATTAAAATTG
CTAAGTAAACAGTAACTTGGTTTTGTAGTGTCATTTTCAGTTAGTGTTTTTATACATTGTCAGT
TTTTAACTAATAGTCCCGTATTCTCACTGGTATTGCTGAAAGGTAGAAAGTTTTTGTTTATTTT
GAAGAAAACTGTGTTTAATTGCTATCCAGAAGTAGGTAATTTTAATATTTCTAAAATGTGATTG
AATTTGAATACATTTCACTATTAGGAAAAGCACAGACTAGGCATTAAGTTTAGATTAGCA

hide sequence

RefSeq Acc Id:

XM_039092321 ⟹ XP_038948249

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	96,501,136 - 96,515,441 (-)	NCBI
mRatBN7.2	14	92,298,461 - 92,313,866 (-)	NCBI

RefSeq Acc Id:

XM_039092323 ⟹ XP_038948251

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	96,501,136 - 96,515,441 (-)	NCBI
mRatBN7.2	14	92,298,461 - 92,313,866 (-)	NCBI

RefSeq Acc Id:

XM_039092324 ⟹ XP_038948252

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	96,501,136 - 96,510,032 (-)	NCBI
mRatBN7.2	14	92,298,461 - 92,313,910 (-)	NCBI

RefSeq Acc Id:

XM_063273495 ⟹ XP_063129565

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	96,501,136 - 96,515,453 (-)	NCBI

RefSeq Acc Id:

XM_063273496 ⟹ XP_063129566

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	96,501,136 - 96,515,453 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102564	(Get FASTA)	NCBI Sequence Viewer
	XP_038948249	(Get FASTA)	NCBI Sequence Viewer
	XP_038948251	(Get FASTA)	NCBI Sequence Viewer
	XP_038948252	(Get FASTA)	NCBI Sequence Viewer
	XP_063129565	(Get FASTA)	NCBI Sequence Viewer
	XP_063129566	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL97918	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000008135
	ENSRNOP00000008135.6
	ENSRNOP00000093008.2

RefSeq Acc Id:

NP_001102564 ⟸ NM_001109094

- UniProtKB:

D3ZQ67 (UniProtKB/TrEMBL), A6JQ01 (UniProtKB/TrEMBL), A0A8I6AIP4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRLKDGATGMSRRRKHADSPVRTRRAGAENCCSAAELWPRASRAARSSQPSRAGTRSALRSQRR
AAADGGRSPGEKETPTQVLKVNLLSCTFSSPNDPDGQTDIFWDQNSPMTKQLGKRRTKRISSAY
SDEISHIVNRIAPQDEKPVTNSMLGVWIGDTAIPCTPSVAKEKSRVKISCTKLKTKNREKELMK
LAQQFDKNMEELDVIQEQDGKNHDFIQMTSEMGHLHNHKNSVQMASDDIVPEVSYTPIKKQVEG
DSRISLGKGQDSSQRPFDRNVEAAFNAIFDGSTQMCSGQLSQELSDTFLNNSKTSMKKENVLLQ
EEIITTETLLTDNLLNKTPISSSPQVDTTIILKSCVTPSPKTPVAPNKHLDELTANDFEDDWES
LLSSEPFLMENAEMLELFPSTTAQGTGQKAVCTSIGENDTITSRANMNLGGRLRDSKVTLDLPS
KTRSRELKNAGECRFSPHPGDEPRKFPFIGNKVRFEKSVTNFVSKNEDYVAVSNLTKVKEDGHG
KGILNASNKSVSYTRYPNEQNHKLGVNLPLKVPTTDPFDSVFVGKENIVCNTNQSHGSKFSSPF
DDWNDPLLASEMIKACHQLETTWEADDVDDDLLYQACDDIERLTQQENKGSKESESKSNTSIHG
SRNTCSASEQGSQLVSSKHWNLVSSPMPLSLTNKSQINKPVTVEKRNICGDCPNILDATNLSVC
SKNSSDNQHVPVQVNSSNSVLVGSSHLKVNLGPVSTKIATNTKFSTAQLSHHSLADTAQSDSKI
LKSSKFTFKKKNPQFLSELNQNPLAGSMPVSKISQDLGKRETVNSWPEANQKHSESLKPSSPDE
EERNRKYSPEEIRRKRQEALVRRKAKALHTVQSAPVSLPW

hide sequence

RefSeq Acc Id:	XP_038948252 ⟸ XM_039092324
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AIP4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948251 ⟸ XM_039092323
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AIP4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948249 ⟸ XM_039092321
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AIP4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000008135 ⟸ ENSRNOT00000008135

Ensembl Acc Id:

ENSRNOP00000093008 ⟸ ENSRNOT00000097260

RefSeq Acc Id:	XP_063129566 ⟸ XM_063273496
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AIP4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129565 ⟸ XM_063273495
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AIP4 (UniProtKB/TrEMBL)

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560957	AgrOrtholog
BioCyc Gene	G2FUF-14920	BioCyc
Ensembl Genes	ENSRNOG00000006185	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000008135	ENTREZGENE
	ENSRNOT00000008135.8	UniProtKB/TrEMBL
	ENSRNOT00000097260.2	UniProtKB/TrEMBL
InterPro	ETAA1	UniProtKB/TrEMBL
KEGG Report	rno:498420	UniProtKB/TrEMBL
NCBI Gene	498420	ENTREZGENE
PANTHER	EWING'S TUMOR-ASSOCIATED ANTIGEN 1	UniProtKB/TrEMBL
	PTHR16434	UniProtKB/TrEMBL
Pfam	ETAA1	UniProtKB/TrEMBL
PhenoGen	Etaa1	PhenoGen
RatGTEx	ENSRNOG00000006185	RatGTEx
UniProt	A0A8I6AIP4	ENTREZGENE, UniProtKB/TrEMBL
	A6JQ01	ENTREZGENE, UniProtKB/TrEMBL
	D3ZQ67	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-08-10	Etaa1	ETAA1 activator of ATR kinase	Etaa1	Ewing tumor-associated antigen 1	Name changed	629549	APPROVED
2023-08-10	Etaa1	Ewing tumor-associated antigen 1	Etaa1l1	Ewing tumor-associated antigen 1-like 1	Name and Symbol changed	629549	APPROVED
2021-03-09	Etaa1l1	Ewing tumor-associated antigen 1-like 1	LOC103693794	ewing's tumor-associated antigen 1 homolog	Data merged from RGD:9426181	737654	PROVISIONAL
2014-08-25	LOC103693794	ewing's tumor-associated antigen 1 homolog			Symbol and Name status set to provisional	70820	PROVISIONAL
2014-07-18	Etaa1l1	Ewing tumor-associated antigen 1-like 1	Etaa1	Ewing tumor-associated antigen 1	Name and Symbol changed	629549	APPROVED
2013-05-24	Etaa1	Ewing tumor-associated antigen 1	LOC680614	similar to ETAA16 protein	Data merged from RGD:1589462	1643240	APPROVED
2008-10-23	Etaa1	Ewing tumor-associated antigen 1	Etaa1	Ewing's tumor-associated antigen 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-28	Etaa1	Ewing's tumor-associated antigen 1	RGD1560957_predicted	similar to RIKEN cDNA 5730466H23 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC680614	similar to ETAA16 protein			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1560957_predicted	similar to RIKEN cDNA 5730466H23 (predicted)	LOC498420	similar to RIKEN cDNA 5730466H23	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498420	similar to RIKEN cDNA 5730466H23			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD