Prrg4 (proline rich and Gla domain 4) - Rat Genome Database

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Gene: Prrg4 (proline rich and Gla domain 4) Rattus norvegicus
Analyze
Symbol: Prrg4
Name: proline rich and Gla domain 4
RGD ID: 1560542
Description: Predicted to enable WW domain binding activity and serine-type endopeptidase activity. Predicted to be involved in blood coagulation and proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space and plasma membrane. Orthologous to human PRRG4 (proline rich and Gla domain 4); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC499847; proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane); RGD1560542; similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4); similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4); transmembrane gamma-carboxyglutamic acid protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83111,669,508 - 111,698,205 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3111,673,582 - 111,698,205 (-)EnsemblGRCr8
mRatBN7.2391,214,646 - 91,243,347 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl391,214,653 - 91,243,273 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx394,712,887 - 94,737,746 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03103,311,955 - 103,336,813 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03101,141,949 - 101,166,975 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0394,783,866 - 94,808,861 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl394,784,008 - 94,808,861 (-)Ensemblrn6Rnor6.0
Rnor_5.03101,408,709 - 101,433,212 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4390,174,070 - 90,198,654 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera390,277,902 - 90,302,157 (-)NCBICelera
Cytogenetic Map3q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
D-glucose  (ISO)
DDE  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fructose  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydroxyurea  (ISO)
indole-3-methanol  (EXP)
lidocaine  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (EXP)
pirinixic acid  (EXP,ISO)
propan-2-ol  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification of key genes and pathways associated with cholangiocarcinoma development based on weighted gene correlation network analysis. Liu J, etal., PeerJ. 2019 Oct 31;7:e7968. doi: 10.7717/peerj.7968. eCollection 2019.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Prrg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83111,669,508 - 111,698,205 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3111,673,582 - 111,698,205 (-)EnsemblGRCr8
mRatBN7.2391,214,646 - 91,243,347 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl391,214,653 - 91,243,273 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx394,712,887 - 94,737,746 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03103,311,955 - 103,336,813 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03101,141,949 - 101,166,975 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0394,783,866 - 94,808,861 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl394,784,008 - 94,808,861 (-)Ensemblrn6Rnor6.0
Rnor_5.03101,408,709 - 101,433,212 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4390,174,070 - 90,198,654 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera390,277,902 - 90,302,157 (-)NCBICelera
Cytogenetic Map3q33NCBI
PRRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381132,829,789 - 32,858,120 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1132,829,675 - 32,858,120 (+)Ensemblhg38GRCh38
GRCh371132,851,473 - 32,879,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361132,808,065 - 32,832,700 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341132,808,064 - 32,832,679NCBI
Celera1132,998,259 - 33,022,871 (+)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1132,545,744 - 32,573,986 (+)NCBIHuRef
CHM1_11132,850,987 - 32,879,156 (+)NCBICHM1_1
T2T-CHM13v2.01132,965,209 - 32,993,360 (+)NCBIT2T-CHM13v2.0
Prrg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392104,657,374 - 104,680,216 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2104,661,086 - 104,680,221 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382104,830,741 - 104,849,872 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2104,830,741 - 104,849,876 (-)Ensemblmm10GRCm38
MGSCv372104,670,898 - 104,690,007 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362104,631,580 - 104,650,513 (-)NCBIMGSCv36mm8
MGSCv362105,736,083 - 105,755,370 (-)NCBIMGSCv36mm8
Celera2106,068,620 - 106,087,797 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.98NCBI
Prrg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,305,549 - 13,326,964 (-)Ensembl
ChiLan1.0NW_00495542213,305,422 - 13,327,188 (-)NCBIChiLan1.0ChiLan1.0
PRRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2935,036,988 - 35,062,204 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11135,042,876 - 35,066,781 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01132,790,274 - 32,816,067 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11132,678,175 - 32,702,877 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1132,678,175 - 32,702,862 (+)EnsemblpanPan2panpan1.1
PRRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11834,755,824 - 34,772,516 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1834,756,080 - 34,772,917 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1834,366,413 - 34,384,074 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01835,365,853 - 35,383,537 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1835,367,097 - 35,383,768 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11834,934,214 - 34,951,871 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01834,518,273 - 34,535,927 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01835,152,840 - 35,170,507 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Prrg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494731,907,850 - 31,928,950 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365335,032,581 - 5,053,529 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365335,032,718 - 5,053,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl228,062,626 - 28,081,249 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1228,061,598 - 28,081,376 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2230,549,353 - 30,569,161 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1132,368,966 - 32,391,490 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl132,364,771 - 32,390,977 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038129,530,230 - 129,553,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prrg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476714,334,465 - 14,387,270 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476714,335,265 - 14,387,271 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Prrg4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1582,740,014 - 82,763,580 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Prrg4
312 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:62
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000038464
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
D3Got42  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83111,696,446 - 111,696,569 (+)Marker Load Pipeline
mRatBN7.2391,241,588 - 91,241,711 (+)MAPPERmRatBN7.2
Rnor_6.0394,807,103 - 94,807,225NCBIRnor6.0
Rnor_5.03101,431,454 - 101,431,576UniSTSRnor5.0
RGSC_v3.4390,196,895 - 90,197,018RGDRGSC3.4
RGSC_v3.4390,196,896 - 90,197,018UniSTSRGSC3.4
Celera390,300,399 - 90,300,521UniSTS
RGSC_v3.1390,093,324 - 90,093,446RGD
RH 3.4 Map3728.5UniSTS
RH 3.4 Map3728.5RGD
RH 2.0 Map3467.1RGD
Cytogenetic Map3q32UniSTS
D3Got44  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2391,241,579 - 91,241,711 (+)MAPPERmRatBN7.2
Rnor_6.0394,807,094 - 94,807,225NCBIRnor6.0
Rnor_5.03101,431,445 - 101,431,576UniSTSRnor5.0
RGSC_v3.4390,196,886 - 90,197,018RGDRGSC3.4
RGSC_v3.4390,196,887 - 90,197,018UniSTSRGSC3.4
Celera390,300,390 - 90,300,521UniSTS
RGSC_v3.1390,093,315 - 90,093,446RGD
RH 3.4 Map3733.6UniSTS
RH 3.4 Map3733.6RGD
RH 2.0 Map3468.0RGD
Cytogenetic Map3q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 158 91 90 59 78 59 6 341 177 11 137 81 92 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000038464   ⟹   ENSRNOP00000032611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3111,673,582 - 111,698,205 (-)Ensembl
mRatBN7.2 Ensembl391,218,587 - 91,243,273 (-)Ensembl
Rnor_6.0 Ensembl394,784,008 - 94,808,861 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116413   ⟹   ENSRNOP00000081249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl391,214,653 - 91,243,264 (-)Ensembl
RefSeq Acc Id: NM_001109203   ⟹   NP_001102673
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83111,673,573 - 111,698,205 (-)NCBI
mRatBN7.2391,218,714 - 91,243,347 (-)NCBI
Rnor_6.0394,783,999 - 94,808,861 (-)NCBI
Rnor_5.03101,408,709 - 101,433,212 (-)NCBI
RGSC_v3.4390,174,070 - 90,198,654 (-)RGD
Celera390,277,902 - 90,302,157 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234655   ⟹   XP_006234717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83111,669,508 - 111,698,158 (-)NCBI
mRatBN7.2391,214,646 - 91,243,308 (-)NCBI
Rnor_6.0394,783,866 - 94,808,558 (-)NCBI
Rnor_5.03101,408,709 - 101,433,212 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001102673 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234717 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79704 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000032611
  ENSRNOP00000032611.4
RefSeq Acc Id: NP_001102673   ⟸   NM_001109203
- Peptide Label: precursor
- UniProtKB: D3ZZA9 (UniProtKB/TrEMBL),   A0A8I5ZRJ1 (UniProtKB/TrEMBL),   A6HNV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234717   ⟸   XM_006234655
- Peptide Label: isoform X1
- UniProtKB: D3ZZA9 (UniProtKB/TrEMBL),   A0A8I5ZRJ1 (UniProtKB/TrEMBL),   A6HNV3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032611   ⟸   ENSRNOT00000038464
Ensembl Acc Id: ENSRNOP00000081249   ⟸   ENSRNOT00000116413
Protein Domains
Gla

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZA9-F1-model_v2 AlphaFold D3ZZA9 1-226 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692264
Promoter ID:EPDNEW_R2789
Type:single initiation site
Name:Prrg4_1
Description:proline rich and Gla domain 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0394,808,787 - 94,808,847EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560542 AgrOrtholog
BioCyc Gene G2FUF-48529 BioCyc
Ensembl Genes ENSRNOG00000022710 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038464 ENTREZGENE
  ENSRNOT00000038464.6 UniProtKB/TrEMBL
Gene3D-CATH 4.10.740.10 UniProtKB/TrEMBL
InterPro Coagulation_fac_subgr_Gla_dom UniProtKB/TrEMBL
  GLA-like_dom_SF UniProtKB/TrEMBL
  GLA_domain UniProtKB/TrEMBL
  Peptidase_S1_coag_factors UniProtKB/TrEMBL
KEGG Report rno:499847 UniProtKB/TrEMBL
NCBI Gene 499847 ENTREZGENE
PANTHER COAGULATION FACTOR UniProtKB/TrEMBL
  TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 4 UniProtKB/TrEMBL
Pfam Gla UniProtKB/TrEMBL
PhenoGen Prrg4 PhenoGen
PRINTS GLABLOOD UniProtKB/TrEMBL
PROSITE GLA_1 UniProtKB/TrEMBL
  GLA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022710 RatGTEx
SMART GLA UniProtKB/TrEMBL
Superfamily-SCOP VitK_dep_GLA UniProtKB/TrEMBL
UniProt A0A8I5ZRJ1 ENTREZGENE
  A6HNV3 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZA9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Prrg4  proline rich and Gla domain 4  Prrg4  proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-28 Prrg4  proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)  RGD1560542_predicted  similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-10 RGD1560542_predicted  similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (predicted)    similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1560542_predicted  similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4) (predicted)  LOC499847  similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499847  similar to Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline-rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4)      Symbol and Name status set to provisional 70820 PROVISIONAL