Ccdc183 (coiled-coil domain containing 183) - Rat Genome Database

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Gene: Ccdc183 (coiled-coil domain containing 183) Rattus norvegicus
Analyze
Symbol: Ccdc183
Name: coiled-coil domain containing 183
RGD ID: 1560370
Description: Orthologous to human CCDC183 (coiled-coil domain containing 183); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); atrazine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: coiled-coil domain-containing protein 183; hypothetical protein LOC499754; LOC499754; uncharacterized protein LOC499754
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,826,918 - 28,837,072 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl328,826,921 - 28,835,326 (-)EnsemblGRCr8
mRatBN7.238,428,784 - 8,438,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,428,787 - 8,437,194 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,533,942 - 11,542,346 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,120,168 - 20,128,572 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,310,015 - 18,318,420 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,832,893 - 2,843,050 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,832,847 - 2,841,331 (-)Ensemblrn6Rnor6.0
Rnor_5.032,814,306 - 2,824,463 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.433,780,803 - 3,789,206 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera33,253,733 - 3,262,136 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Ccdc183
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,826,918 - 28,837,072 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl328,826,921 - 28,835,326 (-)EnsemblGRCr8
mRatBN7.238,428,784 - 8,438,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,428,787 - 8,437,194 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,533,942 - 11,542,346 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,120,168 - 20,128,572 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,310,015 - 18,318,420 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,832,893 - 2,843,050 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,832,847 - 2,841,331 (-)Ensemblrn6Rnor6.0
Rnor_5.032,814,306 - 2,824,463 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.433,780,803 - 3,789,206 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera33,253,733 - 3,262,136 (-)NCBICelera
Cytogenetic Map3p13NCBI
CCDC183
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,796,338 - 136,807,741 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,796,338 - 136,807,741 (+)Ensemblhg38GRCh38
GRCh379139,690,790 - 139,702,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,810,623 - 138,822,014 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349136,969,703 - 136,978,029NCBI
Celera9110,204,424 - 110,215,961 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,149,676 - 109,161,483 (+)NCBIHuRef
CHM1_19139,839,524 - 139,850,724 (+)NCBICHM1_1
T2T-CHM13v2.09149,029,219 - 149,041,903 (+)NCBIT2T-CHM13v2.0
Ccdc183
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,498,641 - 25,507,690 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,498,647 - 25,507,690 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38225,608,629 - 25,617,678 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,608,635 - 25,617,678 (-)Ensemblmm10GRCm38
MGSCv37225,464,149 - 25,473,198 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36225,430,499 - 25,439,668 (-)NCBIMGSCv36mm8
Celera225,336,828 - 25,345,950 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.54NCBI
Ccdc183
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,897,359 - 4,904,559 (+)Ensembl
ChiLan1.0NW_0049555134,897,359 - 4,904,559 (+)NCBIChiLan1.0ChiLan1.0
CCDC183
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,594,041 - 2,608,033 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,596,345 - 2,610,358 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,853,783 - 107,865,565 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,824,266 - 136,835,166 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,824,266 - 136,835,166 (+)EnsemblpanPan2panpan1.1
CCDC183
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,768,012 - 48,775,191 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,981,625 - 47,988,820 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0949,646,181 - 49,653,357 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1948,422,269 - 48,429,493 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,720,963 - 48,728,165 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,767,947 - 48,775,157 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CCDC183
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21313,881,608 - 313,890,325 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC183
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,379,961 - 1,391,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660583,882,262 - 3,894,240 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc183
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,029,257 - 1,037,821 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247601,029,318 - 1,038,375 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ccdc183
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1511,561,546 - 11,570,058 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ccdc183
66 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:37
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000061874
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 9 47 121 58 57 26 55 26 6 237 130 7 95 63 80 31 7 7

Sequence


Ensembl Acc Id: ENSRNOT00000061874   ⟹   ENSRNOP00000058590
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl328,826,921 - 28,835,326 (-)Ensembl
mRatBN7.2 Ensembl38,428,787 - 8,437,194 (-)Ensembl
Rnor_6.0 Ensembl32,832,847 - 2,841,331 (-)Ensembl
RefSeq Acc Id: NM_001025040   ⟹   NP_001020211
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,826,918 - 28,835,326 (-)NCBI
mRatBN7.238,428,784 - 8,437,194 (-)NCBI
Rnor_6.032,832,893 - 2,841,296 (-)NCBI
Rnor_5.032,814,306 - 2,824,463 (-)NCBI
RGSC_v3.433,780,803 - 3,789,206 (-)RGD
Celera33,253,733 - 3,262,136 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233635   ⟹   XP_006233697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,826,918 - 28,837,072 (-)NCBI
mRatBN7.238,428,784 - 8,438,948 (-)NCBI
Rnor_6.032,832,893 - 2,843,050 (-)NCBI
Rnor_5.032,814,306 - 2,824,463 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105661   ⟹   XP_038961589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,826,918 - 28,837,072 (-)NCBI
mRatBN7.238,428,784 - 8,438,948 (-)NCBI
RefSeq Acc Id: XM_039105663   ⟹   XP_038961591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,826,918 - 28,834,839 (-)NCBI
mRatBN7.238,428,786 - 8,437,110 (-)NCBI
RefSeq Acc Id: XR_010064682
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,827,674 - 28,837,072 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001020211 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233697 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961589 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961591 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI60897 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000058590
  ENSRNOP00000058590.2
RefSeq Acc Id: NP_001020211   ⟸   NM_001025040
- UniProtKB: B1H281 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233697   ⟸   XM_006233635
- Peptide Label: isoform X1
- UniProtKB: B1H281 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000058590   ⟸   ENSRNOT00000061874
RefSeq Acc Id: XP_038961589   ⟸   XM_039105661
- Peptide Label: isoform X1
- UniProtKB: B1H281 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961591   ⟸   XM_039105663
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1H281-F1-model_v2 AlphaFold B1H281 1-534 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691886
Promoter ID:EPDNEW_R2410
Type:initiation region
Name:Ccdc183_1
Description:coiled-coil domain containing 183
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.032,841,336 - 2,841,396EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560370 AgrOrtholog
BioCyc Gene G2FUF-50436 BioCyc
Ensembl Genes ENSRNOG00000017044 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061874 ENTREZGENE
  ENSRNOT00000061874.5 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7453119 IMAGE-MGC_LOAD
InterPro CCDC183 UniProtKB/TrEMBL
KEGG Report rno:499754 UniProtKB/TrEMBL
MGC_CLONE MGC:188339 IMAGE-MGC_LOAD
NCBI Gene 499754 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 183 UniProtKB/TrEMBL
  PTHR47115 UniProtKB/TrEMBL
PhenoGen Ccdc183 PhenoGen
RatGTEx ENSRNOG00000017044 RatGTEx
UniProt B1H281 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-12-18 Ccdc183  coiled-coil domain containing 183  LOC499754  hypothetical protein LOC499754  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC499754  hypothetical protein LOC499754      Symbol and Name status set to provisional 70820 PROVISIONAL