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Gene: Sertad1 (SERTA domain containing 1) Rattus norvegicus

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Symbol:

Sertad1

Name:

SERTA domain containing 1

RGD ID:

1549778

Description:

Predicted to enable transcription coactivator activity. Predicted to act upstream of or within negative regulation of cell growth and positive regulation of transcription by RNA polymerase II. Predicted to be located in sarcoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERTAD1 (SERTA domain containing 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

MGC72577; SERTA domain-containing protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SERTAD1 (SERTA domain containing 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SERTAD1 (SERTA domain containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sertad1 (SERTA domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sertad1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	91,903,297 - 91,906,565 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	91,891,814 - 91,907,001 (+)	Ensembl				GRCr8
mRatBN7.2	1	82,775,692 - 82,778,961 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	82,775,252 - 82,779,091 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	88,178,575 - 88,181,840 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	96,665,649 - 96,668,920 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	89,934,440 - 89,937,705 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	84,293,102 - 84,296,370 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	84,293,102 - 84,296,367 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	85,510,198 - 85,513,466 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	82,565,982 - 82,569,250 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	77,190,476 - 77,193,744 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colonic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

azathioprine (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

beta-lapachone (ISO)

bis(2-chloroethyl) sulfide (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

cidofovir anhydrous (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cocaine (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

cytarabine (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

diethyl malate (ISO)

diethyl maleate (ISO)

dioxygen (ISO)

disulfiram (ISO)

dorsomorphin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenofibrate (EXP)

fenpyroximate (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (ISO)

ifosfamide (ISO)

indometacin (ISO)

irinotecan (ISO)

Licochalcone B (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

metformin (EXP)

methamphetamine (EXP)

methapyrilene (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

N-Nitrosopyrrolidine (ISO)

naled (ISO)

nickel atom (ISO)

Nutlin-3 (ISO)

ochratoxin A (ISO)

okadaic acid (ISO)

orphenadrine (EXP)

oxaliplatin (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

pamidronate (ISO)

paracetamol (EXP,ISO)

pentanal (ISO)

phenobarbital (ISO)

picoxystrobin (ISO)

pirinixic acid (ISO)

potassium bromate (ISO)

potassium chromate (ISO)

pyrimidifen (ISO)

quercetin (ISO)

quercitrin (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

SB 431542 (ISO)

SCH 23390 (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

Soman (EXP)

sunitinib (ISO)

tebufenpyrad (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

triphenyl phosphate (ISO)

troglitazone (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell growth (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

Cellular Component

cytoplasm (IBA,ISO)

nucleus (IBA,ISO)

Molecular Function

protein binding (ISO)

transcription coactivator activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:16098148	PMID:24211589

Genomics

Comparative Map Data

Sertad1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	91,903,297 - 91,906,565 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	91,891,814 - 91,907,001 (+)	Ensembl				GRCr8
mRatBN7.2	1	82,775,692 - 82,778,961 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	82,775,252 - 82,779,091 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	88,178,575 - 88,181,840 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	96,665,649 - 96,668,920 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	89,934,440 - 89,937,705 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	84,293,102 - 84,296,370 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	84,293,102 - 84,296,367 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	85,510,198 - 85,513,466 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	82,565,982 - 82,569,250 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	77,190,476 - 77,193,744 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

SERTAD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	40,421,589 - 40,425,992 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	40,421,589 - 40,425,992 (-)	Ensembl			hg38	GRCh38
GRCh37	19	40,927,496 - 40,931,899 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	45,620,248 - 45,623,772 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	45,620,256 - 45,623,738	NCBI
Celera	19	37,727,962 - 37,731,486 (-)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	37,363,411 - 37,366,935 (-)	NCBI		HuRef
CHM1_1	19	40,928,060 - 40,931,584 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	43,242,229 - 43,246,633 (-)	NCBI		T2T-CHM13v2.0

Sertad1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	27,186,378 - 27,189,741 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	27,186,335 - 27,189,741 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	27,486,953 - 27,490,316 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	27,486,910 - 27,490,316 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	28,271,972 - 28,275,333 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	27,195,713 - 27,199,074 (+)	NCBI		MGSCv36	mm8
Celera	7	22,069,329 - 22,072,690 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	15.91	NCBI

Sertad1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955578	848,486 - 852,557 (+)	Ensembl
ChiLan1.0	NW_004955578	848,920 - 852,193 (+)	NCBI	ChiLan1.0	ChiLan1.0

SERTAD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	46,685,563 - 46,689,085 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	48,556,224 - 48,559,746 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	37,471,006 - 37,474,528 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	45,981,064 - 45,984,554 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

SERTAD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	113,270,199 - 113,273,112 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	113,272,051 - 113,272,764 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	112,672,133 - 112,675,051 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	113,868,553 - 113,871,471 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	113,868,588 - 113,871,465 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	113,427,849 - 113,430,769 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	113,060,334 - 113,063,252 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	114,054,300 - 114,057,219 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sertad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	14,364,432 - 14,366,054 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	2,792,850 - 2,793,590 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	2,792,501 - 2,793,901 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SERTAD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	48,698,849 - 48,702,400 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	48,698,881 - 48,702,448 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	44,447,205 - 44,450,392 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SERTAD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	34,878,783 - 34,882,548 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	34,879,118 - 34,879,834 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	12,975,982 - 12,979,752 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sertad1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624925	414,158 - 417,570 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624925	414,158 - 417,592 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sertad1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	168,455,654 - 168,459,066 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sertad1
15 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	46
Interacting mature miRNAs:	55
Transcripts:	ENSRNOT00000028468
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

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alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007735	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000028468 ⟹ ENSRNOP00000028451

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	91,902,810 - 91,906,698 (+)	Ensembl
mRatBN7.2 Ensembl	1	82,775,252 - 82,779,091 (+)	Ensembl
Rnor_6.0 Ensembl	1	84,293,102 - 84,296,367 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000133258 ⟹ ENSRNOP00000112204

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	91,891,814 - 91,907,001 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000145758 ⟹ ENSRNOP00000102776

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	91,901,262 - 91,906,571 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154482 ⟹ ENSRNOP00000111304

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	91,904,366 - 91,906,571 (+)	Ensembl

RefSeq Acc Id:

NM_001007735 ⟹ NP_001007736

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,903,297 - 91,906,565 (+)	NCBI
mRatBN7.2	1	82,775,692 - 82,778,961 (+)	NCBI
Rnor_6.0	1	84,293,102 - 84,296,370 (+)	NCBI
Rnor_5.0	1	85,510,198 - 85,513,466 (+)	NCBI
RGSC_v3.4	1	82,565,982 - 82,569,250 (+)	RGD
Celera	1	77,190,476 - 77,193,744 (+)	RGD

Sequence:

show sequence

CGTCCCAGGTGTCGGTTGCTGGAGCCCAGCGAGCTAGCGATGCTACGGCAGCCGCTTCCTGATT
GGCTGCGTGTGGCTCCCTCTTCGTTCTGATTGGTCGGGAGTGATCTGGAGGATGCTGAGCAAAG
GTCTGAAGCGCAAGCGGGAGGAGGAAGAAACAATGGAGTCCCTCTCAGTGGACTCGTGGTGGTT
GGATCAAAGCCGCCCAGCAGTGGCACAGACCCCAGCAACCGTGGCTTCTAGCTCTCTCTTTGAC
CTCTCGGTGGTCAAGCTCCACCACAGCCTTCGGCAGAGCGAACCAGACCTCCGACACCTGGTGC
TTGTGGTGAACACACTGAGACGAATTCAGGCGTCCATGGAGCCTACGACCGTCCTGCCACCTGA
GCCCATTCAGCCCACAGCCCCCTCTGTGGCAGATAACTTTCTGTCTAGCTCAGACGCCGGCCTC
TCAGCCTCCATGGCCAGCCTCCTGGAAGATCTCAGTCATATTGAGGACCTGAACCAGGTCCCCC
AACCCCAAGCAGACGAGGGGCCTCCAGGCCGCTCTGTCGGGGGTGTCCTGCCCAACCTGGGTGC
CTTGGACTTGCTAGGCCCAGCCACGGGCTGTCTGTTGGACGATGGACTGGAGGGTTTGTTTGAG
GACATTGATACCTCCATGTATGACAGTGAACTTTGGTTACCAGCCTCTGAGGGTCTCAAACCTG
TCCCTGAGAATGGCCCAGCCAAGGAGGAAACTCCAGAGTTGGATGAGGCTGAGCTGGACTACCT
CATGGATGTACTAGTAGGCACACAGGCACTGGAACGGCCACCAGGACCTGGGCGCTGACCCTTA
GACCCAGGGATGATTGACTTGGATCTGAGTTGAGCCTGGTGGTTACACCAATCCACTTTGACGT
GACACAGATGGCTTCCCCTCACAGAGGAGACCCAGGGTCACTTTGGAGAGACAGTGCTGAGTCC
TGGAAACTTCACATCCATCCACCTGTCTTGGCCAGTGAGGGAGTTAGAAATAAGCTCCCAGTGG
TGAAATGACGGGACCCAGAGACAGCAATGGTGTTTGGGCTAGGCTGGGGGTTGGACTGGGATAA
TAGTCTGGGCTATCCCATCCTATTATCCCCAGTGTGGGAAGAGACCTCATAATTTTTGGAAATT
AAAACCAGCTTTGGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001007736	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH61808	(Get FASTA)	NCBI Sequence Viewer
	EDM07953	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000028451.3
	ENSRNOP00000102776
	ENSRNOP00000102776.1
	ENSRNOP00000111304.1
	ENSRNOP00000112204.1

RefSeq Acc Id:

NP_001007736 ⟸ NM_001007735

- UniProtKB:

Q6P771 (UniProtKB/TrEMBL), F7FG80 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSKGLKRKREEEETMESLSVDSWWLDQSRPAVAQTPATVASSSLFDLSVVKLHHSLRQSEPDL
RHLVLVVNTLRRIQASMEPTTVLPPEPIQPTAPSVADNFLSSSDAGLSASMASLLEDLSHIEDL
NQVPQPQADEGPPGRSVGGVLPNLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDSELWLPASE
GLKPVPENGPAKEETPELDEAELDYLMDVLVGTQALERPPGPGR

hide sequence

Ensembl Acc Id:

ENSRNOP00000028451 ⟸ ENSRNOT00000028468

Ensembl Acc Id:

ENSRNOP00000111304 ⟸ ENSRNOT00000154482

Ensembl Acc Id:

ENSRNOP00000102776 ⟸ ENSRNOT00000145758

Ensembl Acc Id:

ENSRNOP00000112204 ⟸ ENSRNOT00000133258

Protein Domains

SERTA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6P771-F1-model_v2	AlphaFold	Q6P771	1-236	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689852

Promoter ID:

EPDNEW_R377

Type:

single initiation site

Name:

Sertad1_1

Description:

SERTA domain containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	84,293,088 - 84,293,148	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1549778	AgrOrtholog
BioCyc Gene	G2FUF-60308	BioCyc
Ensembl Genes	ENSRNOG00000024363	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000028468.8	UniProtKB/TrEMBL
	ENSRNOT00000133258.1	UniProtKB/TrEMBL
	ENSRNOT00000145758	ENTREZGENE
	ENSRNOT00000145758.1	UniProtKB/TrEMBL
	ENSRNOT00000154482.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5598343	IMAGE-MGC_LOAD
InterPro	E2F-SERTA_domain_protein	UniProtKB/TrEMBL
	SERTA	UniProtKB/TrEMBL
KEGG Report	rno:361526	UniProtKB/TrEMBL
MGC_CLONE	MGC:72577	IMAGE-MGC_LOAD
NCBI Gene	361526	ENTREZGENE
PANTHER	CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	SERTA DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
Pfam	SERTA	UniProtKB/TrEMBL
PhenoGen	Sertad1	PhenoGen
PROSITE	SERTA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000024363	RatGTEx
UniProt	F7FG80	ENTREZGENE, UniProtKB/TrEMBL
	Q6P771	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Sertad1	SERTA domain containing 1			Symbol and Name status set to approved	1299863	APPROVED
2005-09-15	Sertad1	SERTA domain containing 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD