Ddx59 (DEAD-box helicase 59) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ddx59 (DEAD-box helicase 59) Rattus norvegicus
Analyze
Symbol: Ddx59
Name: DEAD-box helicase 59
RGD ID: 1359520
Description: Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in orofaciodigital syndrome V. Orthologous to human DDX59 (DEAD-box helicase 59); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DEAD (Asp-Glu-Ala-Asp) box polypeptide 59; DEAD box protein 59; MGC93714; probable ATP-dependent RNA helicase DDX59; similar to RIKEN cDNA 1210002B07; zinc finger HIT domain-containing protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81350,427,940 - 50,452,893 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1350,427,936 - 50,453,208 (+)EnsemblGRCr8
mRatBN7.21347,876,258 - 47,901,214 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1347,876,261 - 47,901,214 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1350,484,328 - 50,509,278 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01351,772,422 - 51,797,372 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01349,039,092 - 49,064,038 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01353,299,872 - 53,324,824 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1353,299,872 - 53,324,824 (+)Ensemblrn6Rnor6.0
Rnor_5.01358,350,167 - 58,375,119 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41349,463,559 - 49,488,659 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1348,187,527 - 48,212,481 (+)NCBICelera
RGSC_v3.11349,477,638 - 49,502,738 (+)NCBI
Cytogenetic Map13q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. null JRS Domain-based curation
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334  


Genomics

Comparative Map Data
Ddx59
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81350,427,940 - 50,452,893 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1350,427,936 - 50,453,208 (+)EnsemblGRCr8
mRatBN7.21347,876,258 - 47,901,214 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1347,876,261 - 47,901,214 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1350,484,328 - 50,509,278 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01351,772,422 - 51,797,372 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01349,039,092 - 49,064,038 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01353,299,872 - 53,324,824 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1353,299,872 - 53,324,824 (+)Ensemblrn6Rnor6.0
Rnor_5.01358,350,167 - 58,375,119 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41349,463,559 - 49,488,659 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1348,187,527 - 48,212,481 (+)NCBICelera
RGSC_v3.11349,477,638 - 49,502,738 (+)NCBI
Cytogenetic Map13q13NCBI
DDX59
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381200,640,805 - 200,669,907 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1200,623,896 - 200,670,049 (-)Ensemblhg38GRCh38
GRCh371200,609,933 - 200,639,035 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361198,859,647 - 198,905,749 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1173,735,739 - 173,761,697 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1171,779,572 - 171,805,597 (-)NCBIHuRef
CHM1_11202,035,807 - 202,061,751 (-)NCBICHM1_1
T2T-CHM13v2.01199,897,729 - 199,926,835 (-)NCBIT2T-CHM13v2.0
Ddx59
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391136,343,009 - 136,384,019 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1136,343,009 - 136,367,896 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381136,415,271 - 136,456,192 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1136,415,271 - 136,440,158 (+)Ensemblmm10GRCm38
MGSCv371138,311,848 - 138,336,728 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361138,231,682 - 138,256,562 (+)NCBIMGSCv36mm8
Celera1139,053,386 - 139,076,977 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map159.73NCBI
Ddx59
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540636,861,259 - 36,885,746 (-)Ensembl
ChiLan1.0NW_00495540636,861,420 - 36,885,746 (-)NCBIChiLan1.0ChiLan1.0
DDX59
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2148,710,017 - 48,756,977 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1148,674,013 - 48,720,484 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01176,227,065 - 176,270,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11180,549,382 - 180,574,699 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1180,532,445 - 180,571,460 (-)EnsemblpanPan2panpan1.1
DDX59
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.172,448,991 - 2,530,076 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl72,501,195 - 2,530,069 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha72,134,545 - 2,209,019 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.072,096,602 - 2,170,953 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl72,148,048 - 2,176,559 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.172,080,622 - 2,155,112 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.072,182,117 - 2,256,638 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.072,213,129 - 2,287,634 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ddx59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934474,422,962 - 74,444,600 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365673,658,230 - 3,679,130 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365673,657,687 - 3,679,276 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX59
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1023,198,798 - 23,221,067 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11023,198,879 - 23,222,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21027,675,641 - 27,699,378 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DDX59
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12528,730,217 - 28,755,879 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2528,730,718 - 28,756,034 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605529,527,920 - 29,561,483 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx59
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248079,951,988 - 9,986,312 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248079,951,423 - 9,985,656 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddx59
340 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:39
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000042846, ENSRNOT00000043798
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134627292251216694Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000042846   ⟹   ENSRNOP00000047251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1350,427,940 - 50,452,893 (+)Ensembl
mRatBN7.2 Ensembl1347,876,261 - 47,901,214 (+)Ensembl
Rnor_6.0 Ensembl1353,299,872 - 53,324,824 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000043798   ⟹   ENSRNOP00000049858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1350,427,940 - 50,452,893 (+)Ensembl
mRatBN7.2 Ensembl1347,876,261 - 47,901,214 (+)Ensembl
Rnor_6.0 Ensembl1353,299,872 - 53,324,824 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115434   ⟹   ENSRNOP00000095305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1350,427,936 - 50,453,208 (+)Ensembl
mRatBN7.2 Ensembl1347,877,846 - 47,901,205 (+)Ensembl
RefSeq Acc Id: NM_001005535   ⟹   NP_001005535
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81350,427,940 - 50,452,893 (+)NCBI
mRatBN7.21347,876,261 - 47,901,214 (+)NCBI
Rnor_6.01353,299,872 - 53,324,824 (+)NCBI
Rnor_5.01358,350,167 - 58,375,119 (+)NCBI
RGSC_v3.41349,463,559 - 49,488,659 (+)RGD
Celera1348,187,527 - 48,212,481 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001190820   ⟹   NP_001177749
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81350,427,940 - 50,452,893 (+)NCBI
mRatBN7.21347,876,261 - 47,901,214 (+)NCBI
Rnor_6.01353,299,872 - 53,324,824 (+)NCBI
Rnor_5.01358,350,167 - 58,375,119 (+)NCBI
Celera1348,187,527 - 48,212,481 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090613   ⟹   XP_038946541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81350,428,007 - 50,452,889 (+)NCBI
mRatBN7.21347,876,258 - 47,901,210 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001005535 (Get FASTA)   NCBI Sequence Viewer  
  NP_001177749 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946541 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81871 (Get FASTA)   NCBI Sequence Viewer  
  EDM09659 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047251
  ENSRNOP00000049858
  ENSRNOP00000049858.2
GenBank Protein Q66HG7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001005535   ⟸   NM_001005535
- Peptide Label: isoform 2
- UniProtKB: Q66HG7 (UniProtKB/Swiss-Prot),   A0A8I6B2D5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001177749   ⟸   NM_001190820
- Peptide Label: isoform 1
- UniProtKB: D4A2T7 (UniProtKB/TrEMBL),   A6ICI8 (UniProtKB/TrEMBL),   A0A8I6B2D5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049858   ⟸   ENSRNOT00000043798
Ensembl Acc Id: ENSRNOP00000047251   ⟸   ENSRNOT00000042846
RefSeq Acc Id: XP_038946541   ⟸   XM_039090613
- Peptide Label: isoform X1
- UniProtKB: D4A2T7 (UniProtKB/TrEMBL),   A6ICI8 (UniProtKB/TrEMBL),   A0A8I6B2D5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095305   ⟸   ENSRNOT00000115434
Protein Domains
DEAD-box RNA helicase Q   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HG7-F1-model_v2 AlphaFold Q66HG7 1-589 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698856
Promoter ID:EPDNEW_R9381
Type:initiation region
Name:Ddx59_1
Description:DEAD-box helicase 59
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01353,299,892 - 53,299,952EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359520 AgrOrtholog
BioCyc Gene G2FUF-18173 BioCyc
Ensembl Genes ENSRNOG00000042451 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042846 ENTREZGENE
  ENSRNOT00000043798 ENTREZGENE
  ENSRNOT00000043798.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.60.220 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7106377 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DEAD_box_RNA_helicase UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  RNA_helicase_DEAD_Q_motif UniProtKB/Swiss-Prot
  Znf_HIT UniProtKB/Swiss-Prot
KEGG Report rno:289402 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93714 IMAGE-MGC_LOAD
NCBI Gene 289402 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBPA UniProtKB/Swiss-Prot
  ATP-DEPENDENT RNA HELICASE RHLE-RELATED UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  zf-HIT UniProtKB/Swiss-Prot
PhenoGen Ddx59 PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
  Q_MOTIF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000042451 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6B2D5 ENTREZGENE, UniProtKB/TrEMBL
  A6ICI8 ENTREZGENE, UniProtKB/TrEMBL
  D4A2T7 ENTREZGENE, UniProtKB/TrEMBL
  DDX59_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Ddx59  DEAD-box helicase 59  Ddx59  DEAD (Asp-Glu-Ala-Asp) box polypeptide 59  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ddx59  DEAD (Asp-Glu-Ala-Asp) box polypeptide 59  MGC93714  similar to RIKEN cDNA 1210002B07  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC93714  similar to RIKEN cDNA 1210002B07      Symbol and Name status set to provisional 70820 PROVISIONAL