Magea13 (MAGE family member A13) - Rat Genome Database

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Gene: Magea13 (MAGE family member A13) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Magea13
Name: MAGE family member A13
RGD ID: 1359246
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEA13P (MAGE family member A13, pseudogene); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC302845; LOC302845; Magea11; melanoma antigen family A, 11; melanoma-associated antigen 11; similar to mage-k1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X142,106,603 - 142,112,462 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX142,106,603 - 142,112,457 (+)EnsemblGRCr8
mRatBN7.2X137,070,707 - 137,076,566 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX136,856,787 - 137,076,564 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX139,270,969 - 139,276,880 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X142,802,607 - 142,808,516 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X140,387,416 - 140,393,329 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X141,847,092 - 141,855,448 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX141,847,092 - 141,855,443 (+)Ensemblrn6Rnor6.0
Rnor_5.0X141,875,018 - 141,880,229 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X144,114,832 - 144,120,821 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX133,180,011 - 133,185,772 (+)NCBICelera
RGSC_v3.1X144,188,264 - 144,194,249 (+)NCBI
Cytogenetic MapXq36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Variants

.
Variants in Magea13
15 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:83
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000004684
Prediction methods:Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1 8 49 80 34 28 20 14 20 130 74 2 71 27 60 8 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000004684   ⟹   ENSRNOP00000004684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX142,106,603 - 142,112,457 (+)Ensembl
mRatBN7.2 EnsemblX137,070,632 - 137,076,564 (+)Ensembl
Rnor_6.0 EnsemblX141,847,092 - 141,855,443 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094741   ⟹   ENSRNOP00000087133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX136,856,787 - 137,076,564 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096869   ⟹   ENSRNOP00000083685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX142,108,844 - 142,112,457 (+)Ensembl
mRatBN7.2 EnsemblX137,073,293 - 137,076,564 (+)Ensembl
RefSeq Acc Id: NM_001013962   ⟹   NP_001013984
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X142,106,603 - 142,112,462 (+)NCBI
mRatBN7.2X137,070,707 - 137,076,566 (+)NCBI
Rnor_6.0X141,847,092 - 141,855,448 (+)NCBI
Rnor_5.0X141,875,018 - 141,880,229 (+)NCBI
RGSC_v3.4X144,114,832 - 144,120,821 (+)RGD
CeleraX133,180,011 - 133,185,772 (+)RGD
Sequence:
RefSeq Acc Id: XM_039099679   ⟹   XP_038955607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X142,108,518 - 142,112,462 (+)NCBI
mRatBN7.2X137,073,280 - 137,076,566 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001013984 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955607 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83676 (Get FASTA)   NCBI Sequence Viewer  
  EDL86163 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004684
  ENSRNOP00000004684.5
  ENSRNOP00000083685
  ENSRNOP00000083685.1
  ENSRNOP00000099532.1
RefSeq Acc Id: NP_001013984   ⟸   NM_001013962
- UniProtKB: Q5XIK4 (UniProtKB/TrEMBL),   A0A8I6G9C6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004684   ⟸   ENSRNOT00000004684
RefSeq Acc Id: XP_038955607   ⟸   XM_039099679
- Peptide Label: isoform X1
- UniProtKB: Q5XIK4 (UniProtKB/TrEMBL),   A0A8I6G9C6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083685   ⟸   ENSRNOT00000096869
Ensembl Acc Id: ENSRNOP00000087133   ⟸   ENSRNOT00000094741
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIK4-F1-model_v2 AlphaFold Q5XIK4 1-314 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359246 AgrOrtholog
BioCyc Gene G2FUF-887 BioCyc
Ensembl Genes ENSRNOG00000003532 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000076083 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004684 ENTREZGENE
  ENSRNOT00000004684.7 UniProtKB/TrEMBL
  ENSRNOT00000096869 ENTREZGENE
  ENSRNOT00000096869.2 UniProtKB/TrEMBL
  ENSRNOT00000135160.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135789 IMAGE-MGC_LOAD
InterPro MAGE UniProtKB/TrEMBL
  MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
KEGG Report rno:302845 UniProtKB/TrEMBL
MGC_CLONE MGC:94523 IMAGE-MGC_LOAD
NCBI Gene 302845 ENTREZGENE
PANTHER MAGE DOMAIN-CONTAINING PROTEIN MAGEA13P-RELATED UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PhenoGen Magea13 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003532 RatGTEx
  ENSRNOG00000076083 RatGTEx
SMART MAGE UniProtKB/TrEMBL
UniProt A0A8I6G9C6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KXQ8_RAT UniProtKB/TrEMBL
  Q5XIK4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-08-06 Magea13  MAGE family member A13  Magea11  melanoma antigen family A, 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-23 Magea11  melanoma antigen family A, 11  LOC302845  similar to mage-k1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 LOC302845  similar to mage-k1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference