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Gene: Heatr5b (HEAT repeat containing 5B) Rattus norvegicus

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Symbol:

Heatr5b

Name:

HEAT repeat containing 5B

RGD ID:

1359216

Description:

Predicted to be involved in endocytosis; intracellular protein localization; and retrograde transport, endosome to Golgi. Predicted to be located in clathrin-coated vesicle and cytosol. Predicted to be active in Golgi apparatus and endocytic vesicle. Orthologous to human HEATR5B (HEAT repeat containing 5B); INTERACTS WITH bisphenol A; methapyrilene; N,N-diethyl-m-toluamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

HEAT repeat-containing protein 5B; LOC362683; similar to RIKEN cDNA D330050P16 gene

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HEATR5B (HEAT repeat containing 5B)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Heatr5b (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Heatr5b (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HEATR5B (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HEATR5B (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Heatr5b (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HEATR5B (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HEATR5B (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Heatr5b (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Heatr5b (HEAT repeat containing 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Heatr5b (HEAT repeat containing 5B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	HEATR5B (HEAT repeat containing 5B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	heatr5b (HEAT repeat containing 5B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG2747	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	LAA1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	soap-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	heatr5b	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	21,995,558 - 22,075,582 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	21,995,602 - 22,075,582 (+)	Ensembl				GRCr8
mRatBN7.2	6	16,243,424 - 16,323,444 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	16,243,461 - 16,323,435 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	16,552,685 - 16,632,177 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	16,874,893 - 16,954,386 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	16,355,859 - 16,435,342 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	1,330,314 - 1,410,339 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	1,330,314 - 1,410,339 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	1,321,469 - 1,401,571 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	1,539,966 - 1,619,714 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	15,898,618 - 15,976,907 (+)	NCBI		Celera
RGSC_v3.1	6	1,539,967 - 1,561,789 (-)	NCBI
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cerebellar Atrophy with Seizures and Variable Developmental Delay (ISO)

pontocerebellar hypoplasia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

chlorpyrifos (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

eugenol (ISO)

folic acid (ISO)

FR900359 (ISO)

hydralazine (ISO)

isoprenaline (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP,ISO)

N,N-diethyl-m-toluamide (EXP)

nickel sulfate (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

potassium chromate (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endocytosis (IBA)

intracellular protein localization (IBA)

protein transport (IEA)

retrograde transport, endosome to Golgi (IBA)

Cellular Component

clathrin-coated vesicle (IEA)

cytoplasmic vesicle (IEA)

cytosol (IEA)

endocytic vesicle (IBA)

Golgi apparatus (IBA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:19946888	PMID:23376485

Genomics

Comparative Map Data

Heatr5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	21,995,558 - 22,075,582 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	21,995,602 - 22,075,582 (+)	Ensembl				GRCr8
mRatBN7.2	6	16,243,424 - 16,323,444 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	16,243,461 - 16,323,435 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	16,552,685 - 16,632,177 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	16,874,893 - 16,954,386 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	16,355,859 - 16,435,342 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	1,330,314 - 1,410,339 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	1,330,314 - 1,410,339 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	1,321,469 - 1,401,571 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	1,539,966 - 1,619,714 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	15,898,618 - 15,976,907 (+)	NCBI		Celera
RGSC_v3.1	6	1,539,967 - 1,561,789 (-)	NCBI
Cytogenetic Map	6	q12	NCBI

HEATR5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	36,980,895 - 37,084,372 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	36,968,383 - 37,084,398 (-)	Ensembl			hg38	GRCh38
GRCh37	2	37,208,038 - 37,311,515 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	37,061,657 - 37,164,989 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	37,049,173 - 37,152,514 (-)	NCBI		Celera
Cytogenetic Map	2	p22.2	NCBI
HuRef	2	36,948,407 - 37,051,685 (-)	NCBI		HuRef
CHM1_1	2	37,137,490 - 37,240,830 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	36,988,032 - 37,091,507 (-)	NCBI		T2T-CHM13v2.0

Heatr5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	79,060,335 - 79,142,810 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	79,060,327 - 79,142,793 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	78,752,906 - 78,835,381 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	78,752,898 - 78,835,364 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	79,152,246 - 79,234,721 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	78,657,962 - 78,740,439 (-)	NCBI		MGSCv36	mm8
Celera	17	83,070,802 - 83,151,994 (-)	NCBI		Celera
Cytogenetic Map	17	E3	NCBI
cM Map	17	49.54	NCBI

Heatr5b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	4,791,317 - 4,879,324 (-)	Ensembl
ChiLan1.0	NW_004955441	4,791,317 - 4,879,318 (-)	NCBI	ChiLan1.0	ChiLan1.0

HEATR5B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	89,397,063 - 89,499,937 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	89,401,039 - 89,506,690 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	37,007,229 - 37,110,082 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	37,772,743 - 37,874,883 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	37,772,743 - 37,874,493 (-)	Ensembl			panPan2	panpan1.1

HEATR5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	29,378,668 - 29,478,394 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	29,378,790 - 29,477,310 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	29,193,273 - 29,292,978 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	30,028,762 - 30,128,507 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	30,028,769 - 30,128,494 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	29,256,384 - 29,356,066 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	29,318,392 - 29,419,108 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	29,537,431 - 29,637,196 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Heatr5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	42,511,729 - 42,593,480 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936663	1,178,221 - 1,258,280 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936663	1,177,283 - 1,245,840 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HEATR5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	103,112,058 - 103,230,551 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	103,112,022 - 103,230,550 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	109,691,754 - 109,810,072 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HEATR5B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	70,314,005 - 70,422,407 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	70,313,203 - 70,425,561 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	41,531,765 - 41,638,239 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Heatr5b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	18,595,841 - 18,696,379 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624738	18,592,274 - 18,696,519 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Heatr5b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	14,401,742 - 14,483,118 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Heatr5b
308 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	69
Count of miRNA genes:	56
Interacting mature miRNAs:	65
Transcripts:	ENSRNOT00000035905
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1975879	46975879	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1975879	46975879	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	44788383	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1975879	46975879	Rat
8693699	Alc37	Alcohol consumption QTL 37	2.6	0.224	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	13717169	27053860	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	1	25740059	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1975879	46975879	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	3239989	48239989	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	3239989	48239989	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	1	40163351	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	14599473	63457687	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	3239989	48239989	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	16089372	61967788	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	3239989	48239989	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1975879	46975879	Rat
8693690	Alc35	Alcohol consumption QTL 35	2.2	0.606	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	13717169	27053860	Rat

Markers in Region

RH137245

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	16,322,970 - 16,323,167 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	1,330,582 - 1,330,778	NCBI	Rnor6.0
Rnor_5.0	6	1,321,737 - 1,321,933	UniSTS	Rnor5.0
RGSC_v3.4	6	1,540,234 - 1,540,430	UniSTS	RGSC3.4
Celera	6	15,976,443 - 15,976,639	UniSTS
RH 3.4 Map	6	31.9	UniSTS
Cytogenetic Map	6	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001414953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000035905 ⟹ ENSRNOP00000035203

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	21,995,602 - 22,075,582 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,243,461 - 16,323,435 (+)	Ensembl
Rnor_6.0 Ensembl	6	1,330,314 - 1,410,339 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098374 ⟹ ENSRNOP00000092384

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	21,995,602 - 22,075,582 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,243,461 - 16,323,435 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000125128 ⟹ ENSRNOP00000104079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	21,995,673 - 22,075,582 (+)	Ensembl

RefSeq Acc Id:

NM_001191064 ⟹ NP_001177993

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	21,995,602 - 22,075,582 (+)	NCBI
mRatBN7.2	6	16,243,459 - 16,323,444 (+)	NCBI
Rnor_6.0	6	1,330,314 - 1,410,339 (-)	NCBI
Rnor_5.0	6	1,321,469 - 1,401,571 (-)	NCBI
Celera	6	15,898,618 - 15,976,907 (+)	NCBI

Sequence:

show sequence

CCGGGTCCCTCGGCAGTGCGGAGCTCAGCTGGTCGGCCCAGACTAGTCTAGGAGGTGTGAAGTA
AGAACATCAATAATGGAGTTAGCTCACAGTTTATTGCTAAATGAAGAAGCGTTGGCTCAGATCA
CGGAAGCAAAGAGACCAGTGTTTATCTTCGAATGGTTAAGATTTCTTGACAAAGTCCTAGTTGC
TGCTAACAAGACAGATGTAAAAGAAAAACAGAAAAAGCTTGTTGAACAATTAACTGGACTAATA
AGCAGCTCGCCTGGACCACCTACTCGAAAACTGTTAGCTAAAAACCTCGCAGCCCTCTATAGCA
TTGGGGATACTTACACAGTTTTCCAGACACTGGATAAATGTAACGACATTATCAGAAGTAAGGA
TGACACTGCGGCCTACTTGCCAACAAAATTGGCAGCAGTGGCTTGTGTTGGAGCATTCTACGAG
AAGATGGGAAGGATGCTGGGCAGTGCATTTCCAGAGACAGTGAACAATCTGTTGAAATCTCTGA
AAAGCGCAGAGTCTCAAGGGCGAAGTGAGATCTTAATGAGTCTGCGGAAAGTGTTGACTGGATT
GGGTGGTGCAGCAGCTTCCTCTCATCGAGACATTTACAAGAACGCTCGATCCCTCCTCACCGAC
AGGTCGATGGCTGTCCGATGTGCAGTGGCCAAGTGCCTTCTGGAACTACAGAATGAAGCTGTTT
TCATGTGGACTGCTGAACTAGAAAATATAGCTACCCTCTGCTTCAAGGCTCTGGAAAACTCAAA
TTATGGGGTGCGAGTCGCAGTGTCCAAACTCCTAGGGACAGTCATGGCTACAGCACTGATGCCA
AAGCAGGCAACAGTCATGCGTCAGAACGTGAAGCGAGCAACGTTTGATGAAGTCTTGGAACTCA
TGGCCACGGGATTTCTGCGTGGAGGGTCAGGTTTCCTAAAGAGTGGTGGAGAAATGTTGAAAGT
TGGAGGGTCTGTTAATCGGGAAGTGAGAGTTGGAGTGACACAGGCCTATGTTGTCTTCGTGACG
ACTTTGGGTGGCCAGTGGCTGGAGCGTAGCTTTGCCACGTTCTTGTCCCACGTACTGGATCTGG
TTTCCCATCCTCGAGCAACACAAACACATGTGGACGCTGTGTACTCAAGGCGATGTGTCTCCTT
CATCCTGAGAGCCACTGTGGGCAGTTTGCTGGGTGAGAAAGCCCAGATAGCAGCTGCCAAGGAA
ATCTGCCAGGCCATCGGGAAGCAGATGAAAGCCGTGGAAGCAGTAGTGAACGATACAAGCAGTG
AGAACAAGTCTGGGGCCGCAGACATCGCCGCCAGCCAGCACGTCATGGTCTGTGCCCTGCAGGA
GCTCGGGAGCCTGGTGCAGAGCCTGAACGCCACCGCCTCCCCTCTTATTCAGGAAGCATCCATA
GGGCTTTTGGAGATTGTGACCTCAGTGCTCCTTCACCCAAGCATGGCTGCTCGGCTGGCTGCTG
CATGGTGTCTGCGTTGTGTGGCGGTGGCCTTGCCTTTCCAGTTGACACCATTTCTGGATAGATG
TGCAGAGCGGCTCAACAACCTCAAGACGTCCCCAGAAGCTGTTAGTGGATACAGTTTTGCAATG
GCTGCTTTGTTGGGAGGCGTGCATCAGTGTCCGTTGGGCATTCCTCACGCCAAAGGAAAGATGG
TGGTCAGCATTGCTGAAGATCTCTTACGAACTGCTGCTCAAAACAGCAGGCTGTCCCTGCAGCG
CACTCAGGCTGGCTGGCTTCTTCTGGGAGCACTCATGACTTTAGGACCATCGGTTGTCCGTTAC
CACCTACCCAAGATGCTGCTGCTGTGGCGGAATGTGTTCCCTCGCTCCCTGAAGGAGCTGGAGG
CTGAGAAGGCCCGAGGGGATTCTTTTACCTGGCAGGTAACTCTGGAAGGTCGTGCTGGAGCTCT
ATGTGCCATGAGGAGTTTTGTTGCGCACTGTCCTGAGCTGCTCACTGAGGATGCGGTTAGGAAA
TTGATGACTCCTATTGAATGTGCCATGACCATGATGTCACACATTCCATCTGTAATTAAGGCCC
ATGGAGCCCACCTGAAAGCTAGTGCTGCAATGGTCCGCTTAAGGCTCTATGATATCCTGGCTTT
ATTACCTCCAAAAACCTATGAAGATCAAGAATCTCAGGTAAAGAGAGCATTTACCTACGTGTTA
GAGCTGCTCCAGCCAAACAGTGCGTCTGGAAGCGGGGCTCTGGAACACGACCCTTCCTCCATTT
ACCTACGCATACCTGCTGGTGAAGCCGTGCCGGGTCCTCTCCCCCTCGGGGTCTCCGTGATTGA
CGCATCCGTGGCTCTTTTTGGGGTTGTGTTTCCACATGTTTCTTATAAACACAGGTTGCAAATG
CTGGATCACTTTGCTGAATGTGTTAAGCAAGCCAAAGGTGTCCGCCAGCAGGCTGTGCAACTCA
ATATATTTACTGCTGTTCTTAGTGCACTGAAGGGCTTAGCTGAAAACAAGAGTACTTTAGGACC
TGAGGAAGTTCGTAAGTCTGCTCTGACACTGGTTATGGGAGCTCTTGACAACCCAAACCCCATC
TTACGGTGTGCAGCAGGAGAAGCCCTTGGAAGAATGGCTCAGGTGGTGGGAGAAGCATCTTTTA
TTGCCCGAATGGCCCAATATAGCTTTGACAAGTTGAAGTCAGCTCGAGATGTTGTATCCAGGAC
TGGTCATTCACTGGCCCTCGGTTGTTTACATCGTTATGTTGGTGGCATAGGATCAGGACAACAC
CTAAAGACCAGTGTCAGCATTTTACTGGCTCTCGCTCAAGATGGGACATCCCCTGAAGTTCAGA
CTTGGTCTCTTCATTCACTTGCTCTGATAGTGGATTCTAGTGGCCCAATGTACCGTGGGTACGT
GGAGCCCACGCTGTCCCTGGTTCTCACCCTGCTGCTGACAGTCCCACCTTCACACACGGAAGTG
CACCAGTGTTTGGGCAGATGCTTGGGGGCGATCATAACTACTGTTGGACCTGAGCTGCAGGGAA
ATGCAGCGACCATTTCCACCATCCGCTCCTCTTGCTTGGTGGGTTGTGCCATCACCCAGGACCA
CTCTGACTCTCTAGTGCAGGCAGCCGCCATCTCTTGCCTTCAACAGCTTCACATGTTTGCCCCA
CGACATGTCAATCTGTCCAGCCTTGTCCCTAGCCTTTGTGTTCACCTATGCAGCTCCCATCTGT
TGCTCCGTCGAGCGGCTGTGGCCTGTCTCCGGCAACTTGCACAAAGAGAAGCAGCAGAAGTGTG
TGAATATGCCATGAGCCTGGCGAAGAATGCAGGGGACAAAGAGATCAGCGGTGGCAATGTCAGT
CCTTTCGCACCTGGAGTTAGTTCTCGCAGTGACATCCATTGCCGGCACCAGGGTGTTAATATCA
CAGACACGGGGCTTGAGGGACTTCTTTTTGGAATGCTAGATCGAGAGACCGACCGAAAACTGTG
CTCTGATATTCACGACACGCTGGGGCACATGCTTTCTTCCCTGGCAGTCGAGAAGCTCTCTCAC
TGGTTACCGCTCTGTAAAGACGTCTTAGCAGCTTCCAGTGATATGAGTGCGGCAACGCTCTTAA
GCAGTGGGAAAGATGAAGAGTCTGAGAAGAAAGATGAGATGGATGACGACGCCATGTTCACCAC
ACTAGGCGAGGAGGACAAGTCAAAGCCTTTCGTGGCTCCTCGATGGGCCACTCGGGTGTTTGCC
GCAGACTGCCTATGCCGAATCATCAACCTGTGTGAGAACGCAGACCAGGCTCACTTCGATCTTG
CCTTGGCACGGTCTGCTAAACTACGAAACCCAAAAAATGACCTCTTGGTATTACATCTCTCTGA
CCTGATTCGAATGGCATTCATGGCTGCAACTGATCATAGCAACCAACTGCGAATGGCTGGGCTC
CAGGCACTTGAAGACATTATCAAGAAATTTGCATCTGTGCCTGAGCCAGAATTTCCAGGTCATG
TGATCCTGGAGCAGTATCAAGCTAATGTGGGAGCTGCCCTAAGACCAGCTTTTTCACAAGATAC
GCCATCAGACATAATAGCAAAAGCTTGCCAGGTGTGCAGCACGTGGATTGGAAGTGGTGTTGTC
AGCGATCTCAATGACCTCCGTCGGGTGCATAATCTACTCGTTTCCTCTCTGGACAAAGTTCAGG
CTGGAAAGGGATCTCCTAGTCAACTGTACCGAGAGAGTGCCACCACCATGGAGAAGCTGGCTGT
TCTTAAGGCGTGGGCAGAGGTATATGTGGTTGCTATGAATATTAAGAAAGAAGCAGAGTCAAAA
CCGAAGAGAGCAATGAAAAATACTGATGATGATGATGATGACTTTGGCACCATAGACGAACTAC
CTCCCGACAGTTTAATAACCCTAGTGCAGCCCGAGCTGCCAACTCTCAGCCGCCTGTGGCTGGC
CGCGTTGAAAGACTACGCACTTCTGACTTTACCAGCTGAGTTCTCTAGTCAGCTTCCCCCAGAT
GGAGGAGCATTTTACACTCCCGAGACCATCGATACAGCGAGACTTCACTACCGGAACTCCTGGG
CCCCAATTCTCCATGCAGTGGCACTTTGGTTAAACAGCACAGGATTTACATGTCAGGAGTCCAC
AGAAGCCACAGCTGTATCTGGAGGACAGAAGCGCTCCCCGGCTGTCAGTTTAAACCAGGTTCCA
GGAGCCATGGCTAGTGCTAAACCCCTGCCAGAAGTTAACAAAGACAGAATGCACCTGATCCTAG
GTGTGAGTATACAGTTTCTTTGTTCCCCTCGACCAGAGGAGCCCATTGAACACGTTACAGCATG
CCTGCAGGCCTTACACACCTTACTGGGCTCTCCTTATGCACGAATACACATTGCAGAAGATCAG
CTGATTGGTGTTGAGTTGCTAAGTGTCCTGCACCGCCTGTTACTGACCTGGAACCCACCGTCCA
TCCAACTGCTGGTCACTGGAGTCGTGCAGCAGATTGTCAGGGCCGCGCAGGACTATCTACAAGA
AAAGAGAAGTGCTCTAAATGAAGAGGATATGGAAAAAGAGTCCTGTCCTGCACTAGGAGAAGGG
GGTGACACCGGCGGCCTCATTCCTGGAAAGTCCCTTGTGTTTGCAACCATGGAGCTGCTGATGT
TCATTTTAGTACGGCATATGCCACACCTGAGTACCAAGATGTCGGACTCTCCAAGTCACGTGGC
CACAAAGACTCACCTGTCCGAAGAAAGCGCTCGCTTGGTGGCAGCCACAGTGACCATTCTCTCA
GACTTGCCATCACTCTGTTCACCAGCTGGATGTATGACAATCCTGCCTACAATTCTGTTCTTAA
TTGCAAGAATATTGAAAGACACAGCAATAAAATCTGTGGACAACCATGTTTCTCCCCCAGTCAG
TGCAGCTCTTCAGGGGATAAAAAGTATTGTGACACTTTCTATGGCCAAAACAGAGGAAACTCAG
AAACAGTGGACAGCTCTAATCCGGAGCACTCTTGCCTGCATCCTGGAATATTCCCAACCAGATG
ACTGTATGCCCGCACCGGATGAAGTGAGCACACTTACAGCCATTGCGCTCTTCCTGTGGTCTGC
CAGCAGTGAGATAATAGGAGTGCAGTCCCTACAGAACGGCTGCATGAACAGATTTAAAAGTGCC
CTGAACTCGTGTGACCCATGGGTTCAAGCCAAATGCTACCAGCTTCTCCTCTCAGTCTTCCAGC
ATTCCAACCGTGCGCTCTCGACTCCCTACATCCACTCCTTAGCTCCACTAGTGGTCGGGAAGCT
GAAAGCTGTGGAGAGAGACAGACCAGCCAGTAGCACGGAACTTCTGGCTGTCCAAGAAGGAATT
AAAGTTCTTGAAACATTGGTTGCTCTTGGGGAAGAACAGAACAGAGTCCAGTTACTCGCTCTTC
TGGTGCCCACTTTGATCTCCTACCTGCTGGACGAAAACTCATTCGCCTCAGCAAGTTCCATCTC
CAAAGATCTTCATGAGTTTGCACTCCAGAACTTAATGCATATTGGACCTCTGTACCCACACGCT
TTCAAGACGGTAATGGGGGCTGCTCCTGAGCTGAAAGCGCGACTAGAAACCGCTGTCCGAGCCA
GCCAGGCGAGCAAAGCCAAAGCAGCCGCGAGGCAGCCTGCCCCTGCCACGCACTCCGCACCAAC
CATTAAGCTGAAAACAAGCTTTTTCTAGTGCGTCCTTCCCTTCACCTGCATTTACATTCCATGG
AGTTAGTGACAACCCCACGTCATTCCAGGCCGTGGACTGTTTTATCTGTATATCGGAATTATAA
TGCTTTGCAGTTGGTTAAGTGAAATAGTGTTTATACCTCTTACTGATTTTTAAAAATCATGTGG
TAAATATATTTTCATTTTTATCCTAATGATATTTCTCTTTTGTTGATTTATTTTTGTTGTTCCT
GTTGGGGTTTTGTTTCTGGTTTTTGGTACAGGTAACTGGACCCAGAGCCTTGCTCATTGTAAGC
ATGCACTGGACTGTCATATGCCCCTAGACCCTAATTAACTTATTGGTTTTAACTCTAAGCCATG
GTGTTTTAAATTTGTTAGAATAGAATTGTATCATGTAGTTGGGCAGCCATTGGATAGTATCAAG
AAAAGAAAATGGGTCAATTTTTAGCGTTTGTCATGATAAGTTAATTGAAAAGCAAACAGATTAT
AAGTTGGAAGTGACTCAAATAACAGAAAAGTCTGTTTTATGGCAAATATCCTATGAATAAAATC
ACATTTTCTAACCAT

hide sequence

RefSeq Acc Id:

NM_001414953 ⟹ NP_001401882

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	21,995,602 - 22,075,582 (+)	NCBI
mRatBN7.2	6	16,243,459 - 16,323,444 (+)	NCBI

RefSeq Acc Id:

XM_039112448 ⟹ XP_038968376

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	21,995,558 - 22,074,671 (+)	NCBI
mRatBN7.2	6	16,243,424 - 16,322,507 (+)	NCBI

RefSeq Acc Id:

XM_039112449 ⟹ XP_038968377

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	21,995,558 - 22,072,679 (+)	NCBI
mRatBN7.2	6	16,243,424 - 16,320,539 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001177993	(Get FASTA)	NCBI Sequence Viewer
	NP_001401882	(Get FASTA)	NCBI Sequence Viewer
	XP_038968376	(Get FASTA)	NCBI Sequence Viewer
	XP_038968377	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79335	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000035203
	ENSRNOP00000035203.6
	ENSRNOP00000092384
	ENSRNOP00000092384.1
	ENSRNOP00000104079.1

RefSeq Acc Id:	NP_001177993 ⟸ NM_001191064
- Peptide Label:	isoform 2
- UniProtKB:	F1LST0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELAHSLLLNEEALAQITEAKRPVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSP GPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAAYLPTKLAAVACVGAFYEKMGR MLGSAFPETVNNLLKSLKSAESQGRSEILMSLRKVLTGLGGAAASSHRDIYKNARSLLTDRSMA VRCAVAKCLLELQNEAVFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQAT VMRQNVKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGG QWLERSFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQA IGKQMKAVEAVVNDTSSENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLE IVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALL GGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPK MLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAVRKLMTP IECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEDQESQVKRAFTYVLELLQ PNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHF AECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDNPNPILRCA AGEALGRMAQVVGEASFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTS VSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCL GRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVN LSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKEISGGNVSPFAP GVSSRSDIHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLPL CKDVLAASSDMSAATLLSSGKDEESEKKDEMDDDAMFTTLGEEDKSKPFVAPRWATRVFAADCL CRIINLCENADQAHFDLALARSAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALE DIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLN DLRRVHNLLVSSLDKVQAGKGSPSQLYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRA MKNTDDDDDDFGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAF YTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCQESTEATAVSGGQKRSPAVSLNQVPGAMA SAKPLPEVNKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLGSPYARIHIAEDQLIGV ELLSVLHRLLLTWNPPSIQLLVTGVVQQIVRAAQDYLQEKRSALNEEDMEKESCPALGEGGDTG GLIPGKSLVFATMELLMFILVRHMPHLSTKMSDSPSHVATKTHLSEESARLVAATVTILSDLPS LCSPAGCMTILPTILFLIARILKDTAIKSVDNHVSPPVSAALQGIKSIVTLSMAKTEETQKQWT ALIRSTLACILEYSQPDDCMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSC DPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPLVVGKLKAVERDRPASSTELLAVQEGIKVLE TLVALGEEQNRVQLLALLVPTLISYLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTV MGAAPELKARLETAVRASQASKAKAAARQPAPATHSAPTIKLKTSFF hide sequence

Ensembl Acc Id:

ENSRNOP00000035203 ⟸ ENSRNOT00000035905

RefSeq Acc Id:	XP_038968376 ⟸ XM_039112448
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038968377 ⟸ XM_039112449
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000092384 ⟸ ENSRNOT00000098374

RefSeq Acc Id:	NP_001401882 ⟸ NM_001414953
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I6GJQ5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000104079 ⟸ ENSRNOT00000125128

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LST0-F1-model_v2	AlphaFold	F1LST0	1-2030	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694352

Promoter ID:

EPDNEW_R4877

Type:

multiple initiation site

Name:

Heatr5b_1

Description:

HEAT repeat containing 5B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	1,410,341 - 1,410,401	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359216	AgrOrtholog
BioCyc Gene	G2FUF-38486	BioCyc
Ensembl Genes	ENSRNOG00000025926	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000035905	ENTREZGENE
	ENSRNOT00000035905.7	UniProtKB/TrEMBL
	ENSRNOT00000098374	ENTREZGENE
	ENSRNOT00000098374.2	UniProtKB/TrEMBL
	ENSRNOT00000125128.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7097335	IMAGE-MGC_LOAD
InterPro	ARM-like	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	Laa1/Sip1/HEATR5-like_HEAT	UniProtKB/TrEMBL
	Laa1/Sip1/HEATR5/SWEETIE	UniProtKB/TrEMBL
MGC_CLONE	MGC:94766	IMAGE-MGC_LOAD
NCBI Gene	362683	ENTREZGENE
PANTHER	HEAT REPEAT-CONTAINING PROTEIN 5B	UniProtKB/TrEMBL
	PTHR21663	UniProtKB/TrEMBL
Pfam	HEAT_HEATR5A	UniProtKB/TrEMBL
	Laa1_Sip1_HTR5	UniProtKB/TrEMBL
	TPR_LAA1_C	UniProtKB/TrEMBL
PhenoGen	Heatr5b	PhenoGen
RatGTEx	ENSRNOG00000025926	RatGTEx
Superfamily-SCOP	ARM-type_fold	UniProtKB/TrEMBL
UniProt	A0A8I6GJQ5	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LGW6_RAT	UniProtKB/TrEMBL
	F1LST0	ENTREZGENE, UniProtKB/TrEMBL
	Q6AXS6_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-05	Heatr5b	HEAT repeat containing 5B	LOC362683	similar to RIKEN cDNA D330050P16 gene	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC362683	similar to RIKEN cDNA D330050P16 gene	LOC362684	similar to KIAA1414 protein	Data merged from RGD:1583830	1643240	APPROVED
2006-11-19	LOC362684	similar to KIAA1414 protein			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-07-29	LOC362683	similar to RIKEN cDNA D330050P16 gene			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar