Akap8l (A-kinase anchoring protein 8 like) - Rat Genome Database

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Pathways
Gene: Akap8l (A-kinase anchoring protein 8 like) Rattus norvegicus
Analyze
Symbol: Akap8l
Name: A-kinase anchoring protein 8 like
RGD ID: 1359200
Description: Predicted to enable histone deacetylase binding activity; lamin binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including cell cycle G2/M phase transition; mitotic chromosome condensation; and regulation of mRNA export from nucleus. Predicted to be located in chromatin; cytoplasm; and nuclear speck. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nuclear matrix. Orthologous to human AKAP8L (A-kinase anchoring protein 8 like); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: A kinase (PRKA) anchor protein 8-like; A-kinase anchor protein 8-like; LOC299569; similar to NAKAP95
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,983,215 - 12,012,843 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl711,982,721 - 12,012,811 (-)EnsemblGRCr8
mRatBN7.2711,332,671 - 11,362,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,332,672 - 11,362,275 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx714,151,159 - 14,180,750 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0716,028,581 - 16,058,168 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,900,096 - 13,929,674 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0714,340,168 - 14,369,835 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl714,340,170 - 14,369,821 (-)Ensemblrn6Rnor6.0
Rnor_5.0714,494,264 - 14,524,003 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4712,889,649 - 12,919,236 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera79,443,795 - 9,473,308 (-)NCBICelera
RGSC_v3.1712,889,649 - 12,919,236 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
imidacloprid  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
nefazodone  (EXP)
nitrates  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thiabendazole  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (IEA,ISO)
cytoplasm  (IEA,ISO)
nuclear matrix  (IBA,IEA,ISO)
nuclear speck  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
ribonucleoprotein complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11034899   PMID:11402034   PMID:11884601   PMID:16391387   PMID:16980585   PMID:17594903   PMID:22658674   PMID:22681889   PMID:31505169  


Genomics

Comparative Map Data
Akap8l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,983,215 - 12,012,843 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl711,982,721 - 12,012,811 (-)EnsemblGRCr8
mRatBN7.2711,332,671 - 11,362,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,332,672 - 11,362,275 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx714,151,159 - 14,180,750 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0716,028,581 - 16,058,168 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,900,096 - 13,929,674 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0714,340,168 - 14,369,835 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl714,340,170 - 14,369,821 (-)Ensemblrn6Rnor6.0
Rnor_5.0714,494,264 - 14,524,003 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4712,889,649 - 12,919,236 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera79,443,795 - 9,473,308 (-)NCBICelera
RGSC_v3.1712,889,649 - 12,919,236 (-)NCBI
Cytogenetic Map7q11NCBI
AKAP8L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,380,050 - 15,418,988 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,380,050 - 15,419,141 (-)Ensemblhg38GRCh38
GRCh371915,490,861 - 15,529,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,351,859 - 15,390,833 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341915,351,858 - 15,390,833NCBI
Celera1915,386,496 - 15,425,477 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1915,058,829 - 15,097,763 (-)NCBIHuRef
CHM1_11915,490,499 - 15,529,470 (-)NCBICHM1_1
T2T-CHM13v2.01915,505,027 - 15,543,979 (-)NCBIT2T-CHM13v2.0
Akap8l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391732,540,398 - 32,569,589 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1732,540,398 - 32,569,581 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381732,321,424 - 32,350,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1732,321,424 - 32,350,607 (-)Ensemblmm10GRCm38
MGSCv371732,458,369 - 32,487,522 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361732,053,032 - 32,082,199 (-)NCBIMGSCv36mm8
Celera1733,242,263 - 33,271,406 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.5NCBI
Akap8l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,839,339 - 7,874,432 (+)Ensembl
ChiLan1.0NW_0049554957,839,339 - 7,874,432 (+)NCBIChiLan1.0ChiLan1.0
AKAP8L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22020,293,841 - 20,332,210 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11919,296,597 - 19,334,983 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,912,960 - 14,950,479 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,897,896 - 15,936,684 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,897,969 - 15,936,486 (-)EnsemblpanPan2panpan1.1
AKAP8L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,773,585 - 46,800,544 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2046,747,062 - 46,817,240 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2046,621,143 - 46,648,110 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02047,260,225 - 47,287,202 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,232,152 - 47,287,197 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,495,088 - 46,522,051 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,911,738 - 46,938,694 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,185,246 - 47,212,220 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Akap8l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,539,079 - 205,574,596 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,088,361 - 5,123,649 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,088,260 - 5,123,735 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP8L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,184,763 - 62,221,935 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1262,184,735 - 62,241,631 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2261,760,062 - 61,797,260 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AKAP8L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,987,731 - 14,023,130 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,987,736 - 14,023,148 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660745,484,922 - 5,520,168 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Akap8l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,472,029 - 2,508,129 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249012,471,957 - 2,508,248 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Akap8l
260 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:71
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000008560
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
RH133817  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2711,332,819 - 11,333,001 (+)MAPPERmRatBN7.2
Rnor_6.0714,340,317 - 14,340,498NCBIRnor6.0
Rnor_5.0714,494,413 - 14,494,594UniSTSRnor5.0
RGSC_v3.4712,889,797 - 12,889,978UniSTSRGSC3.4
Celera79,443,943 - 9,444,124UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC085785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000008560   ⟹   ENSRNOP00000008560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl711,982,721 - 12,012,811 (-)Ensembl
mRatBN7.2 Ensembl711,332,672 - 11,362,275 (-)Ensembl
Rnor_6.0 Ensembl714,340,170 - 14,369,821 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090673   ⟹   ENSRNOP00000071522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl711,332,672 - 11,356,629 (-)Ensembl
Rnor_6.0 Ensembl714,340,236 - 14,364,178 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110147   ⟹   ENSRNOP00000092015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl711,983,028 - 12,007,068 (-)Ensembl
mRatBN7.2 Ensembl711,332,672 - 11,356,529 (-)Ensembl
RefSeq Acc Id: NM_001013946   ⟹   NP_001013968
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,983,216 - 12,012,811 (-)NCBI
mRatBN7.2711,332,672 - 11,362,273 (-)NCBI
Rnor_6.0714,340,169 - 14,369,821 (-)NCBI
Rnor_5.0714,494,264 - 14,524,003 (-)NCBI
RGSC_v3.4712,889,649 - 12,919,236 (-)RGD
Celera79,443,795 - 9,473,308 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241054   ⟹   XP_006241116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,983,215 - 12,012,843 (-)NCBI
mRatBN7.2711,332,671 - 11,362,287 (-)NCBI
Rnor_6.0714,340,168 - 14,369,835 (-)NCBI
Rnor_5.0714,494,264 - 14,524,003 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241055   ⟹   XP_006241117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,984,382 - 12,012,843 (-)NCBI
mRatBN7.2711,339,206 - 11,362,287 (-)NCBI
Rnor_6.0714,346,563 - 14,369,835 (-)NCBI
Rnor_5.0714,494,264 - 14,524,003 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078627   ⟹   XP_038934555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,995,395 - 12,012,843 (-)NCBI
mRatBN7.2711,344,769 - 11,362,287 (-)NCBI
RefSeq Acc Id: XM_039078629   ⟹   XP_038934557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,996,710 - 12,012,843 (-)NCBI
mRatBN7.2711,345,958 - 11,362,287 (-)NCBI
RefSeq Acc Id: XM_063263156   ⟹   XP_063119226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,984,382 - 12,012,843 (-)NCBI
RefSeq Acc Id: XM_063263157   ⟹   XP_063119227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,996,710 - 12,012,843 (-)NCBI
RefSeq Acc Id: XM_063263158   ⟹   XP_063119228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,996,060 - 12,012,843 (-)NCBI
RefSeq Acc Id: XM_063263159   ⟹   XP_063119229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,996,710 - 12,012,843 (-)NCBI
RefSeq Acc Id: XR_001838673
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,983,726 - 12,012,843 (-)NCBI
mRatBN7.2711,332,671 - 11,362,287 (-)NCBI
Rnor_6.0714,340,168 - 14,369,835 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005486554
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,984,382 - 12,012,843 (-)NCBI
mRatBN7.2711,339,206 - 11,362,287 (-)NCBI
RefSeq Acc Id: XR_010052949
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,995,395 - 12,012,843 (-)NCBI
RefSeq Acc Id: XR_010052950
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,995,395 - 12,012,843 (-)NCBI
RefSeq Acc Id: NP_001013968   ⟸   NM_001013946
- UniProtKB: Q5U306 (UniProtKB/TrEMBL),   F1LP74 (UniProtKB/TrEMBL),   A0A9K3Y6N0 (UniProtKB/TrEMBL),   A0A0G2K0P0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241116   ⟸   XM_006241054
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0P0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241117   ⟸   XM_006241055
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000008560   ⟸   ENSRNOT00000008560
Ensembl Acc Id: ENSRNOP00000071522   ⟸   ENSRNOT00000090673
RefSeq Acc Id: XP_038934555   ⟸   XM_039078627
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934557   ⟸   XM_039078629
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000092015   ⟸   ENSRNOT00000110147
RefSeq Acc Id: XP_063119226   ⟸   XM_063263156
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063119228   ⟸   XM_063263158
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063119229   ⟸   XM_063263159
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063119227   ⟸   XM_063263157
- Peptide Label: isoform X4
Protein Domains
C2H2 AKAP95-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0P0-F1-model_v2 AlphaFold A0A0G2K0P0 1-641 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695067
Promoter ID:EPDNEW_R5592
Type:initiation region
Name:Akap8l_1
Description:A-kinase anchoring protein 8 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0714,369,788 - 14,369,848EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359200 AgrOrtholog
BioCyc Gene G2FUF-34828 BioCyc
Ensembl Genes ENSRNOG00000006355 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008560 ENTREZGENE
  ENSRNOT00000008560.9 UniProtKB/TrEMBL
  ENSRNOT00000110147 ENTREZGENE
  ENSRNOT00000110147.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7108413 IMAGE-MGC_LOAD
InterPro AKAP95 UniProtKB/TrEMBL
  ZF_C2H2_AKAP95 UniProtKB/TrEMBL
KEGG Report rno:299569 UniProtKB/TrEMBL
MGC_CLONE MGC:93758 IMAGE-MGC_LOAD
NCBI Gene 299569 ENTREZGENE
PANTHER A-KINASE ANCHOR PROTEIN 8-LIKE UniProtKB/TrEMBL
  AKAP95 UniProtKB/TrEMBL
Pfam AKAP95 UniProtKB/TrEMBL
PhenoGen Akap8l PhenoGen
PROSITE ZF_C2H2_AKAP95 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006355 RatGTEx
UniProt A0A0G2K0P0 ENTREZGENE
  A0A8I6AV30_RAT UniProtKB/TrEMBL
  A0A9K3Y6N0 ENTREZGENE, UniProtKB/TrEMBL
  A6K946_RAT UniProtKB/TrEMBL
  F1LP74 ENTREZGENE
  Q5U306 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LP74 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Akap8l  A-kinase anchoring protein 8 like  Akap8l  A kinase (PRKA) anchor protein 8-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Akap8l  A kinase (PRKA) anchor protein 8-like      Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC299569  similar to NAKAP95      Symbol and Name status set to provisional 70820 PROVISIONAL