Pdhb (pyruvate dehydrogenase E1 subunit beta) - Rat Genome Database

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Gene: Pdhb (pyruvate dehydrogenase E1 subunit beta) Rattus norvegicus
Analyze
Symbol: Pdhb
Name: pyruvate dehydrogenase E1 subunit beta
RGD ID: 1359146
Description: Enables pyruvate dehydrogenase (acetyl-transferring) activity. Involved in pyruvate decarboxylation to acetyl-CoA. Part of pyruvate dehydrogenase complex. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHB (pyruvate dehydrogenase E1 subunit beta); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; Leigh disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC94149; PDHE1-B; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 beta subunit; pyruvate dehydrogenase E1 component subunit beta, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bmd62
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81519,182,789 - 19,188,731 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1519,181,208 - 19,188,976 (+)EnsemblGRCr8
mRatBN7.21516,752,561 - 16,758,503 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1516,750,980 - 16,758,500 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1518,927,415 - 18,933,373 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01519,885,878 - 19,891,836 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01518,140,784 - 18,146,742 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01518,540,826 - 18,546,855 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,539,210 - 18,546,854 (+)Ensemblrn6Rnor6.0
Rnor_5.01522,507,861 - 22,513,890 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41518,737,449 - 18,743,391 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1516,710,789 - 16,716,731 (+)NCBICelera
RGSC_v3.11518,737,448 - 18,743,390 (+)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
aspartame  (ISO)
Azaspiracid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
chromium trinitrate  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
Diosbulbin B  (ISO)
doxorubicin  (EXP,ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
eugenol  (EXP)
ferric ammonium citrate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glucose  (EXP)
glyphosate  (ISO)
heparin  (EXP)
isoniazide  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
methamphetamine  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
monosodium L-glutamate  (ISO)
morphine  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oxidopamine  (ISO)
paracetamol  (ISO)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
quartz  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sarin  (EXP,ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
sulforaphane  (EXP)
T-2 toxin  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mutations in the gene for the E1beta subunit: a novel cause of pyruvate dehydrogenase deficiency. Brown RM, etal., Hum Genet. 2004 Jul;115(2):123-7. Epub 2004 May 11.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Characterization of two cDNA clones for pyruvate dehydrogenase E1 beta subunit and its regulation in tricarboxylic acid cycle-deficient fibroblast. Huh TL, etal., J Biol Chem 1990 Aug 5;265(22):13320-6.
4. Pretranslational regulation of pyruvate dehydrogenase complex subunits in white adipose tissue during the suckling-weaning transition in the rat. Maury J, etal., Biochem J. 1995 Oct 15;311 ( Pt 2):531-5.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases. Patel MS and Korotchkina LG, Exp Mol Med. 2001 Dec 31;33(4):191-7.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:2025639   PMID:14651853   PMID:15489334   PMID:18164639   PMID:18614015   PMID:19081061   PMID:21630459   PMID:22569713   PMID:23376485   PMID:25002582   PMID:25451023   PMID:26316108  
PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Pdhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81519,182,789 - 19,188,731 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1519,181,208 - 19,188,976 (+)EnsemblGRCr8
mRatBN7.21516,752,561 - 16,758,503 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1516,750,980 - 16,758,500 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1518,927,415 - 18,933,373 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01519,885,878 - 19,891,836 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01518,140,784 - 18,146,742 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01518,540,826 - 18,546,855 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,539,210 - 18,546,854 (+)Ensemblrn6Rnor6.0
Rnor_5.01522,507,861 - 22,513,890 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41518,737,449 - 18,743,391 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1516,710,789 - 16,716,731 (+)NCBICelera
RGSC_v3.11518,737,448 - 18,743,390 (+)NCBI
Cytogenetic Map15p14NCBI
PDHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38358,427,630 - 58,433,832 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl358,427,630 - 58,434,012 (-)Ensemblhg38GRCh38
GRCh37358,413,357 - 58,419,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36358,388,394 - 58,394,605 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34358,388,397 - 58,394,594NCBI
Celera358,427,174 - 58,433,398 (-)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef358,509,470 - 58,515,692 (-)NCBIHuRef
CHM1_1358,363,623 - 58,369,848 (-)NCBICHM1_1
T2T-CHM13v2.0358,468,008 - 58,474,213 (-)NCBIT2T-CHM13v2.0
Pdhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391414,296,470 - 14,303,782 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1414,296,748 - 14,303,777 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38148,165,991 - 8,173,303 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl148,165,996 - 8,173,025 (-)Ensemblmm10GRCm38
MGSCv37148,998,505 - 9,005,506 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36146,956,612 - 6,964,490 (-)NCBIMGSCv36mm8
Celera143,789,851 - 3,797,024 (-)NCBICelera
Cytogenetic Map14A1NCBI
cM Map144.74NCBI
Pdhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554301,707,615 - 1,713,541 (+)Ensembl
ChiLan1.0NW_0049554301,707,615 - 1,713,541 (+)NCBIChiLan1.0ChiLan1.0
PDHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2258,398,731 - 58,405,135 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1358,403,507 - 58,409,861 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0358,359,753 - 58,366,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1359,776,216 - 59,782,461 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl359,776,618 - 59,782,411 (-)EnsemblpanPan2panpan1.1
PDHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12032,185,420 - 32,191,592 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2032,110,558 - 32,116,683 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02032,453,097 - 32,459,222 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2032,453,107 - 32,459,214 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12031,909,791 - 31,915,922 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02032,266,176 - 32,272,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02032,438,275 - 32,444,406 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pdhb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,442,034 - 169,447,686 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364732,580,618 - 2,586,266 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364732,580,642 - 2,586,266 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1340,160,568 - 40,167,476 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11340,161,519 - 40,167,502 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21344,121,821 - 44,127,805 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12219,718,610 - 19,725,037 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2219,718,353 - 19,725,036 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041147,098,867 - 147,105,329 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdhb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248225,482,173 - 5,488,287 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248225,482,177 - 5,488,218 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pdhb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11278,585,523 - 78,591,411 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pdhb
45 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:38
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000010545
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat

Markers in Region
RH127408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21516,758,210 - 16,758,390 (+)MAPPERmRatBN7.2
Rnor_6.01518,546,563 - 18,546,742NCBIRnor6.0
Rnor_5.01522,513,598 - 22,513,777UniSTSRnor5.0
RGSC_v3.41518,743,099 - 18,743,278UniSTSRGSC3.4
Celera1516,716,439 - 16,716,618UniSTS
RH 3.4 Map15145.48UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010545   ⟹   ENSRNOP00000010545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1519,183,102 - 19,188,729 (+)Ensembl
mRatBN7.2 Ensembl1516,752,873 - 16,758,499 (+)Ensembl
Rnor_6.0 Ensembl1518,540,913 - 18,546,854 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083212   ⟹   ENSRNOP00000075450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1519,181,208 - 19,188,976 (+)Ensembl
mRatBN7.2 Ensembl1516,750,980 - 16,758,500 (+)Ensembl
Rnor_6.0 Ensembl1518,539,210 - 18,546,673 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107037   ⟹   ENSRNOP00000090069
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1519,181,208 - 19,188,976 (+)Ensembl
mRatBN7.2 Ensembl1516,750,980 - 16,758,499 (+)Ensembl
RefSeq Acc Id: NM_001007620   ⟹   NP_001007621
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,182,789 - 19,188,731 (+)NCBI
mRatBN7.21516,752,561 - 16,758,503 (+)NCBI
Rnor_6.01518,540,913 - 18,546,855 (+)NCBI
Rnor_5.01522,507,861 - 22,513,890 (+)NCBI
RGSC_v3.41518,737,449 - 18,743,391 (+)RGD
Celera1516,710,789 - 16,716,731 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001007621 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79137 (Get FASTA)   NCBI Sequence Viewer  
  EDL94164 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010545
GenBank Protein P49432 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007621   ⟸   NM_001007620
- Peptide Label: precursor
- UniProtKB: Q6AY95 (UniProtKB/Swiss-Prot),   P49432 (UniProtKB/Swiss-Prot),   A0A8L2Q513 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010545   ⟸   ENSRNOT00000010545
Ensembl Acc Id: ENSRNOP00000075450   ⟸   ENSRNOT00000083212
Ensembl Acc Id: ENSRNOP00000090069   ⟸   ENSRNOT00000107037
Protein Domains
Transketolase-like pyrimidine-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49432-F1-model_v2 AlphaFold P49432 1-359 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699589
Promoter ID:EPDNEW_R10112
Type:multiple initiation site
Name:Pdhb_1
Description:pyruvate dehydrogenase E1 beta subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01518,541,210 - 18,541,270EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359146 AgrOrtholog
BioCyc Gene G2FUF-14288 BioCyc
BioCyc Pathway PYRUVDEHYD-PWY [pyruvate decarboxylation to acetyl CoA I] BioCyc
BioCyc Pathway Image PYRUVDEHYD-PWY BioCyc
Ensembl Genes ENSRNOG00000007895 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010545 ENTREZGENE
Gene3D-CATH 3.40.50.920 UniProtKB/Swiss-Prot
  3.40.50.970 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127701 IMAGE-MGC_LOAD
InterPro PDHB UniProtKB/Swiss-Prot
  THDP-binding UniProtKB/Swiss-Prot
  Transketo_C/PFOR_II UniProtKB/Swiss-Prot
  Transketolase-like_Pyr-bd UniProtKB/Swiss-Prot
  Transketolase_C UniProtKB/Swiss-Prot
KEGG Report rno:289950 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94149 IMAGE-MGC_LOAD
NCBI Gene 289950 ENTREZGENE
PANTHER PTHR11624 UniProtKB/Swiss-Prot
  PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam Transket_pyr UniProtKB/Swiss-Prot
  Transketolase_C UniProtKB/Swiss-Prot
PhenoGen Pdhb PhenoGen
RatGTEx ENSRNOG00000007895 RatGTEx
SMART Transket_pyr UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52518 UniProtKB/Swiss-Prot
  SSF52922 UniProtKB/Swiss-Prot
UniProt A0A0G2KAM3_RAT UniProtKB/TrEMBL
  A0A8I6A8K3_RAT UniProtKB/TrEMBL
  A0A8L2Q513 ENTREZGENE, UniProtKB/TrEMBL
  A6K0B7_RAT UniProtKB/TrEMBL
  ODPB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6AY95 ENTREZGENE
UniProt Secondary Q6AY95 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Pdhb  pyruvate dehydrogenase E1 subunit beta  Pdhb  pyruvate dehydrogenase E1 beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-08-22 Pdhb  pyruvate dehydrogenase E1 beta subunit  Pdhb  pyruvate dehydrogenase (lipoamide) beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Pdhb  pyruvate dehydrogenase (lipoamide) beta      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Pdhb  pyruvate dehydrogenase (lipoamide) beta      Symbol and Name status set to provisional 70820 PROVISIONAL